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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:indocyanine green
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Accession:CHEBI:31696 term browser browse the term
Definition:A benzoindole that has formula C43H47N2NaO6S2.
Synonyms:exact_synonym: sodium 4-(2-{7-[1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indolium-2-yl]hepta-2,4,6-trien-1-ylidene}-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)butane-1-sulfonate
 related_synonym: Cardio-Green;   Formula=C43H47N2NaO6S2;   Fox Green;   InChI=1S/C43H48N2O6S2.Na/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1;   InChIKey=MOFVSTNWEDAEEK-UHFFFAOYSA-M;   SMILES=[Na+].[H]C(=C([H])C([H])=C([H])C1=[N+](CCCCS([O-])(=O)=O)c2ccc3ccccc3c2C1(C)C)C([H])=C([H])C([H])=C1N(CCCCS([O-])(=O)=O)c2ccc3ccccc3c2C1(C)C
 xref: Beilstein:4115884;   CAS:3599-32-4;   KEGG:D01342
 xref_mesh: MESH:D007208
 xref: Wikipedia:Indocyanine_Green



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indocyanine green term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Indocyanine Green inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Indocyanine Green results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 affects export ISO ABCB4 protein affects the export of Indocyanine Green CTD PMID:11302927 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Indocyanine Green results in increased expression of BAX mRNA; Indocyanine Green results in increased expression of BAX protein CTD PMID:23675521 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Casp9 caspase 9 increases expression ISO Indocyanine Green results in increased expression of CASP9 mRNA; Indocyanine Green results in increased expression of CASP9 protein CTD PMID:23675521 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases uptake
multiple interactions
ISO SLC10A1 protein results in increased uptake of Indocyanine Green
Nifedipine promotes the reaction [SLC10A1 protein results in increased uptake of Indocyanine Green]; Taurocholic Acid inhibits the reaction [SLC10A1 protein results in increased uptake of Indocyanine Green]
CTD PMID:32209977 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases uptake ISO SLC10A2 protein results in increased uptake of Indocyanine Green CTD PMID:32209977 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO Indocyanine Green inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO Indocyanine Green inhibits the reaction [SLC22A7 protein results in increased uptake of Glutarates] CTD PMID:12065749 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP Indocyanine Green inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:10224140 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        dye 2970
          cyanine dye 11
            indocyanine green 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      chalcogen 19612
                        oxygen atom 19586
                          oxygen molecular entity 19586
                            oxide 12769
                              oxoanion 10311
                                chalcogen oxoanion 659
                                  sulfur oxoanion 657
                                    sulfonate 113
                                      organosulfonate oxoanion 113
                                        alkanesulfonate oxoanion 9
                                          1,1-diunsubstituted alkanesulfonate 9
                                            indocyanine green 9
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