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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Iguratimod
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Accession:CHEBI:31689 term browser browse the term
Synonyms:related_synonym: Formula=C17H14N2O6S;   InChI=1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20);   InChIKey=ANMATWQYLIFGOK-UHFFFAOYSA-N;   SMILES=C1=C(C(=CC2=C1OC=C(C2=O)NC=O)OC3=CC=CC=C3)NS(C)(=O)=O;   T-614;   careram;   kolbet
 xref: CAS:123663-49-0;   Drug_Central:4894;   KEGG:D01146
 xref_mesh: MESH:C077313


show annotations for term's descendants           Sort by:
Iguratimod term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta decreases expression
multiple interactions		 EXP T 614 results in decreased expression of IL1B protein
Methotrexate promotes the reaction [T 614 results in decreased expression of IL1B protein]		 CTD PMID:19019215 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions		 EXP T 614 results in decreased expression of IL6 protein
Methotrexate promotes the reaction [T 614 results in decreased expression of IL6 protein]		 CTD PMID:19019215 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 EXP T 614 results in decreased expression of TNF protein
Methotrexate promotes the reaction [T 614 results in decreased expression of TNF protein]		 CTD PMID:19019215 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          carbon atom 19698
            organic molecular entity 19698
              Iguratimod 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            Iguratimod 3
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