Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Ibudilast
go back to main search page
Accession:CHEBI:31684 term browser browse the term
Synonyms:related_synonym: Formula=C14H18N2O;   InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3;   InChIKey=ZJVFLBOZORBYFE-UHFFFAOYSA-N;   KP-305;   SMILES=CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C;   ketas
 alt_id: CHEBI:92295
 xref: CAS:50847-11-5;   Drug_Central:1406;   HMDB:HMDB0015614;   KEGG:D01385;   LINCS:LSM-2357
 xref_mesh: MESH:C038366


show annotations for term's descendants           Sort by:
 
Ibudilast term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma decreases expression ISO ibudilast results in decreased expression of IFNG protein CTD PMID:14664469 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il12a interleukin 12A decreases expression
multiple interactions
ISO ibudilast results in decreased expression of IL12A mRNA
ibudilast results in decreased expression of [IL12A protein binds to IL12B protein]
CTD PMID:14664469 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B decreases expression
multiple interactions
ISO ibudilast results in decreased expression of IL12B mRNA
ibudilast results in decreased expression of [IL12A protein binds to IL12B protein]
CTD PMID:14664469 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          nitrogen atom 18565
            nitrogen molecular entity 18565
              organonitrogen compound 18338
                organonitrogen heterocyclic compound 17485
                  pyrazolopyridine 7
                    Ibudilast 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      p-block molecular entity 19702
                        carbon group molecular entity 19608
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic heterocyclic compound 18432
                                  organic heteropolycyclic compound 17844
                                    organic heterobicyclic compound 16765
                                      pyrazolopyridine 7
                                        Ibudilast 3
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.