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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Ibudilast
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Accession:CHEBI:31684 term browser browse the term
Synonyms:related_synonym: Formula=C14H18N2O;   InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3;   InChIKey=ZJVFLBOZORBYFE-UHFFFAOYSA-N;   KP-305;   SMILES=CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C;   ketas
 alt_id: CHEBI:92295
 xref: CAS:50847-11-5;   Drug_Central:1406;   HMDB:HMDB0015614;   KEGG:D01385;   LINCS:LSM-2357
 xref_mesh: MESH:C038366


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Ibudilast term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma decreases expression ISO ibudilast results in decreased expression of IFNG protein CTD PMID:14664469 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il12a interleukin 12A decreases expression
multiple interactions
ISO ibudilast results in decreased expression of IL12A mRNA
ibudilast results in decreased expression of [IL12A protein binds to IL12B protein]
CTD PMID:14664469 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B decreases expression
multiple interactions
ISO ibudilast results in decreased expression of IL12B mRNA
ibudilast results in decreased expression of [IL12A protein binds to IL12B protein]
CTD PMID:14664469 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          nitrogen atom 18565
            nitrogen molecular entity 18565
              organonitrogen compound 18335
                organonitrogen heterocyclic compound 17481
                  pyrazolopyridine 7
                    Ibudilast 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      p-block molecular entity 19696
                        carbon group molecular entity 19599
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteropolycyclic compound 17838
                                    organic heterobicyclic compound 16763
                                      pyrazolopyridine 7
                                        Ibudilast 3
paths to the root