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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fulvestrant
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Accession:CHEBI:31638 term browser browse the term
Definition:A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.
Synonyms:exact_synonym: 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol
 related_synonym: (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol;   Faslodex;   Formula=C32H47F5O3S;   ICI-182780;   InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29?,30+,41?/m1/s1;   InChIKey=VWUXBMIQPBEWFH-WCCTWKNTSA-N;   SMILES=C=1C=C(C=C2C1[C@]3(CC[C@@]4([C@H](CC[C@]4([C@@]3([C@@H](C2)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F)[H])[H])O)C)[H])O;   fulvestrantum
 alt_id: CHEBI:87729
 xref: CAS:129453-61-8;   DrugBank:DB00947;   Drug_Central:1255;   KEGG:D01161;   LINCS:LSM-6504
 xref_mesh: MESH:C070081
 xref: PMID:18683044;   PMID:19369092;   PMID:21319872;   PMID:21699443;   PMID:25720568;   Wikipedia:Fulvestrant


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fulvestrant term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
ISO
EXP
fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCB1 protein]; fulvestrant inhibits the reaction [Genistein results in increased expression of ABCB1 protein]
Fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of ABCB1A mRNA]; Fulvestrant inhibits the reaction [tetrabromobisphenol A results in decreased expression of and results in decreased activity of ABCB1A protein]; Fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCB1A mRNA]
fulvestrant results in increased expression of ABCB1 protein
CTD PMID:23707492 PMID:24685904 PMID:30830211 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B multiple interactions EXP fulvestrant inhibits the reaction [estradiol 3-benzoate results in decreased expression of ABCB1B mRNA] CTD PMID:23707492 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
ISO
EXP
fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCC2 protein]; fulvestrant inhibits the reaction [Genistein results in increased expression of ABCC2 protein]
EGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]]; fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]
fulvestrant results in increased expression of ABCC2 protein
CTD PMID:24685904 PMID:25813982 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO fulvestrant results in increased expression of ABCC3 mRNA CTD PMID:15072547 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions EXP fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of ABCC4 mRNA]; fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC4 mRNA] CTD PMID:23707492 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases expression
multiple interactions
ISO
EXP
fulvestrant results in decreased expression of ABCC5 mRNA
fulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC5 mRNA]
CTD PMID:15072547 PMID:23707492 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
affects response to substance
ISO
EXP
fulvestrant affects the reaction [4-nonylphenol results in decreased expression of ABCG2 protein]; fulvestrant affects the reaction [bisphenol A results in decreased expression of ABCG2 protein]; fulvestrant affects the reaction [Estradiol results in decreased expression of ABCG2 protein]; fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]; fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]; fulvestrant inhibits the reaction [Estriol results in increased expression of ABCG2 mRNA]; fulvestrant inhibits the reaction [Estriol results in increased expression of ABCG2 protein]; fulvestrant inhibits the reaction [Genistein results in decreased expression of ABCG2 protein]
fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCG2 protein]
ABCG2 affects the susceptibility to fulvestrant
CTD PMID:17823853 PMID:24169358 PMID:24945792 PMID:26850786 PMID:27036933 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression ISO fulvestrant results in decreased expression of ABHD2 mRNA CTD PMID:26865669 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
JBrowse link
G Acvr2b activin A receptor type 2B multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in decreased expression of ACVR2B mRNA] CTD PMID:14994273 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Adora1 adenosine A1 receptor decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of ADORA1 mRNA
Fulvestrant inhibits the reaction [arsenite results in increased expression of ADORA1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of ADORA1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ADORA1 mRNA]
CTD PMID:31646340 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of AGER protein] CTD PMID:15878629 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member affects response to substance ISO AGR2 protein affects the susceptibility to fulvestrant CTD PMID:20525379 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371
JBrowse link
G Agt angiotensinogen multiple interactions ISO
EXP
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of AGT mRNA]
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of AGT mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of AGT protein]
CTD PMID:30677511 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO fulvestrant results in decreased expression of AHNAK mRNA CTD PMID:16514628 NCBI chr 1:205,882,223...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression
increases activity
ISO [fulvestrant results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; fulvestrant inhibits the reaction [Estradiol results in increased expression of AHR protein]; fulvestrant promotes the reaction [formononetin results in increased activity of AHR protein]
Fulvestrant results in increased expression of AHR mRNA
CTD PMID:19901195 PMID:28618207 PMID:28985473 PMID:31646340 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akap1 A-kinase anchoring protein 1 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of AKAP1 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of AKAP1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of AKAP1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of AKAP1 mRNA]
CTD PMID:31646340 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
[Fulvestrant co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with ESR1 protein] results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [puerarin results in increased phosphorylation of AKT1 protein]
fulvestrant results in increased phosphorylation of AKT1 protein
fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]
[Estradiol co-treated with Fulvestrant] results in increased phosphorylation of AKT1 protein; Fulvestrant inhibits the reaction [Promegestone results in increased phosphorylation of AKT1 protein]
CTD PMID:16020483 PMID:16168102 PMID:16951259 PMID:17125913 PMID:18767177 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase increases expression ISO fulvestrant results in increased expression of ALAD mRNA CTD PMID:26865669 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO fulvestrant inhibits the reaction [[6-(1,1-dimethylallyl)naringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[8-prenylnaringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[Coumestrol binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[Estradiol binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[naringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of AP3B1 mRNA
arsenite inhibits the reaction [Fulvestrant results in decreased expression of AP3B1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of AP3B1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in decreased expression of AP3B1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of AP3B1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of AP3B1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of AP3B1 mRNA]
CTD PMID:31646340 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
JBrowse link
G Aplf aprataxin and PNKP like factor increases expression
multiple interactions
ISO Fulvestrant results in increased expression of APLF mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of APLF mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of APLF mRNA]
CTD PMID:31646340 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO fulvestrant inhibits the reaction [Quercetin results in increased secretion of APOA1 protein] CTD PMID:24963805 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apod apolipoprotein D increases expression ISO fulvestrant results in increased expression of APOD mRNA CTD PMID:16514628 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP fulvestrant inhibits the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form] CTD PMID:25461682 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
decreases expression
decreases activity
ISO
EXP
Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to AR protein]]; Fulvestrant inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Fulvestrant inhibits the reaction [Estradiol results in increased activity of AR protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of AR mRNA]
fulvestrant inhibits the reaction [Testosterone results in increased expression of AR mRNA]
fulvestrant results in increased expression of AR protein
fulvestrant results in decreased expression of AR mRNA
fulvestrant results in decreased activity of AR protein
CTD PMID:11867264 PMID:15026081 PMID:15316697 PMID:15925091 PMID:17823853 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Areg amphiregulin increases expression
multiple interactions
decreases expression
ISO fulvestrant results in increased expression of AREG mRNA
Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of AREG mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of AREG mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of AREG mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of AREG mRNA]
Fulvestrant results in decreased expression of AREG mRNA
CTD PMID:15072547 PMID:16202921 PMID:16514628 PMID:26865669 PMID:31059536 More... NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg1 arginase 1 multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol F results in decreased expression of ARG1 mRNA]; Fulvestrant inhibits the reaction [bisphenol F results in decreased expression of ARG1 protein] CTD PMID:32044397 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arid1a AT-rich interaction domain 1A increases expression
decreases response to substance
ISO fulvestrant results in increased expression of ARID1A protein
ARID1A gene mutant form results in decreased susceptibility to Fulvestrant
CTD PMID:24169358 PMID:31932695 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 increases expression ISO fulvestrant results in increased expression of ARNT2 mRNA CTD PMID:16514628 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
JBrowse link
G Artn artemin multiple interactions
decreases response to substance
ISO ARTN protein inhibits the reaction [fulvestrant inhibits the reaction [Estradiol results in increased expression of BCL2 protein]]; fulvestrant inhibits the reaction [Estradiol results in increased expression of ARTN mRNA]; YC137 inhibits the reaction [ARTN protein inhibits the reaction [fulvestrant inhibits the reaction [Estradiol results in increased expression of BCL2 protein]]]
ARTN protein results in decreased susceptibility to fulvestrant
CTD PMID:20305694 NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of ASNS mRNA
fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ASNS mRNA]; fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ASNS mRNA]
CTD PMID:16467188 PMID:16514628 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ATF4 mRNA]; fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ATF4 mRNA] CTD PMID:16467188 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO fulvestrant results in increased expression of ATP5F1B mRNA CTD PMID:20211987 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Aurka aurora kinase A decreases expression ISO fulvestrant results in decreased expression of AURKA mRNA CTD PMID:16514628 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Aurkb aurora kinase B multiple interactions
decreases expression
ISO [Fulvestrant co-treated with Sirolimus] results in decreased expression of AURKB mRNA; Fulvestrant inhibits the reaction [arsenite results in increased expression of AURKB mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of AURKB mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of AURKB mRNA]
Fulvestrant results in decreased expression of AURKB mRNA
CTD PMID:19016759 PMID:31646340 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in decreased expression of BAD protein modified form]] CTD PMID:23419388 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] inhibits the reaction [Estradiol results in decreased expression of BAX protein]; [Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BAX protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of BAX protein]; Fulvestrant inhibits the reaction [Methoxychlor results in decreased expression of BAX mRNA]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in decreased expression of BAX protein]; Fulvestrant inhibits the reaction [Triclosan results in decreased expression of BAX mRNA] CTD PMID:15870704 PMID:24835555 PMID:33484789 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member affects response to substance
multiple interactions
increases expression
ISO BCAR1 affects the susceptibility to fulvestrant
Fulvestrant inhibits the reaction [Estradiol results in decreased expression of BCAR1 mRNA]
Fulvestrant results in increased expression of BCAR1 mRNA
CTD PMID:24169358 PMID:31646340 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member affects response to substance ISO BCAR3 affects the susceptibility to Fulvestrant CTD PMID:24169358 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
[Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] inhibits the reaction [Estradiol results in increased expression of BCL2 protein]; ARTN protein inhibits the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased expression of BCL2 protein]]; Fulvestrant inhibits the reaction [[aluminum chlorhydrate results in increased abundance of Aluminum] which results in decreased expression of BCL2 protein]; Fulvestrant inhibits the reaction [alachlor results in increased expression of BCL2 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of BCL2 protein]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of BCL2 protein]; YC137 inhibits the reaction [ARTN protein inhibits the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased expression of BCL2 protein]]]
fulvestrant results in increased expression of BCL2 protein
[fulvestrant co-treated with Estradiol] results in increased expression of BCL2 protein
CTD PMID:10545406 PMID:15870704 PMID:16951259 PMID:20305694 PMID:31945389 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of BCL2L1 protein]] CTD PMID:23419388 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of BCL2L2 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of BCL2L2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of BCL2L2 mRNA] CTD PMID:31646340 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of BDNF mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of BDNF mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of BDNF mRNA] CTD PMID:31646340 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estradiol results in increased expression of BGLAP mRNA]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of BGLAP mRNA]; fulvestrant inhibits the reaction [resveratrol results in increased expression of BGLAP mRNA]
fulvestrant inhibits the reaction [naringin results in increased secretion of BGLAP protein]
CTD PMID:17689939 PMID:23596885 PMID:26362186 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO
EXP
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased expression of BIRC5 protein]]; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]]; [Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in decreased expression of BIRC5 protein; [Fulvestrant co-treated with Sirolimus] results in decreased expression of BIRC5 mRNA; Fulvestrant inhibits the reaction [Estradiol results in increased expression of BIRC5 protein]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]; Fulvestrant promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Estradiol results in increased expression of BIRC5 protein]]; Fulvestrant promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of BIRC5 protein]]
fulvestrant results in decreased expression of BIRC5 mRNA
CTD PMID:19016759 PMID:21980073 PMID:33484789 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blm BLM RecQ like helicase multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of BLM mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of BLM mRNA] CTD PMID:17268063 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]; fulvestrant inhibits the reaction [resveratrol results in increased expression of BMP2 mRNA]
fulvestrant inhibits the reaction [naringin results in increased secretion of BMP2 protein]
CTD PMID:17513867 PMID:23596885 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions
increases expression
ISO Cadmium inhibits the reaction [Fulvestrant results in increased expression of BMP4 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of BMP4 mRNA] CTD PMID:31646340 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [bisphenol A results in decreased expression of BMP7 mRNA]
Fulvestrant results in increased expression of BMP7 mRNA
CTD PMID:14994273 PMID:31646340 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of BRCA1 mRNA
Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of BRCA1 mRNA]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BRCA1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of BRCA1 mRNA]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of BRCA1 mRNA]
CTD PMID:12473173 PMID:20206645 PMID:31646340 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of BUB1 mRNA
fulvestrant results in decreased expression of BUB1 mRNA
CTD PMID:19016759 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of BUB1B mRNA
fulvestrant results in decreased expression of BUB1B mRNA
CTD PMID:19016759 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C3 complement C3 multiple interactions
decreases expression
increases expression
EXP
ISO
fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of C3 mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA]; fulvestrant inhibits the reaction [Triclosan results in increased expression of C3 mRNA]
arsenite inhibits the reaction [Fulvestrant results in decreased expression of C3 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of C3 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in decreased expression of C3 mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of C3 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of C3 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of C3 mRNA]
fulvestrant results in increased expression of C3 mRNA; fulvestrant results in increased expression of C3 protein
CTD PMID:11086226 PMID:12858169 PMID:16639590 PMID:22062131 PMID:31646340 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions
decreases expression
ISO fulvestrant inhibits the reaction [Genistein results in increased expression of CA12 mRNA]; fulvestrant promotes the reaction [Dexamethasone inhibits the reaction [Genistein results in increased expression of CA12 mRNA]]
fulvestrant results in decreased expression of CA12 mRNA
CTD PMID:25136773 PMID:26865669 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of CAD mRNA] CTD PMID:16675542 NCBI chr 6:25,292,133...25,315,176
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Capn1 calpain 1 multiple interactions ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [fulvestrant promotes the reaction [CAPN1 protein results in increased cleavage of and results in increased activity of CAPN1 protein]]; fulvestrant promotes the reaction [CAPN1 protein results in increased cleavage of and results in increased activity of CAPN1 protein]; GPER1 protein affects the reaction [fulvestrant promotes the reaction [CAPN1 protein results in increased cleavage of and results in increased activity of CAPN1 protein]] CTD PMID:24440569 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of CARM1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of CARM1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of CARM1 mRNA] CTD PMID:31646340 NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
JBrowse link
G Casp3 caspase 3 multiple interactions EXP fulvestrant affects the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased cleavage of and results in increased activity of CASP3 protein]]; fulvestrant inhibits the reaction [Estradiol results in increased activity of CASP3 protein] CTD PMID:23419388 PMID:23788033 PMID:25461682 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO fulvestrant results in increased expression of CASP4 mRNA CTD PMID:12154049 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Estradiol co-treated with Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased cleavage of CASP9 protein; [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased cleavage of CASP9 protein; Fulvestrant inhibits the reaction [[aluminum chlorhydrate results in increased abundance of Aluminum] which results in decreased expression of CASP9 protein] CTD PMID:31945389 PMID:33484789 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cav1 caveolin 1 multiple interactions
decreases expression
EXP
ISO
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 protein]
arsenite inhibits the reaction [Fulvestrant results in decreased expression of CAV1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of CAV1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in decreased expression of CAV1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of CAV1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of CAV1 mRNA]
CTD PMID:17091190 PMID:31646340 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbx1 chromobox 1 decreases expression ISO fulvestrant results in decreased expression of CBX1 mRNA CTD PMID:16514628 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Cckar cholecystokinin A receptor multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CCKAR mRNA]; Fulvestrant inhibits the reaction [Genistein results in increased expression of CCKAR mRNA]; Fulvestrant inhibits the reaction [isoliquiritigenin results in increased expression of CCKAR mRNA] CTD PMID:26789235 PMID:27702603 PMID:31593742 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [arsenite results in decreased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; Fulvestrant inhibits the reaction [Estradiol results in decreased activity of CCL2 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; Fulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased activity of CCL2 protein]
Fulvestrant results in increased expression of CCL2 mRNA
CTD PMID:10614622 PMID:17006379 PMID:31217279 PMID:31646340 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO fulvestrant results in increased expression of CCL20 mRNA CTD PMID:16298037 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO fulvestrant results in increased expression of CCL5 mRNA CTD PMID:12154049 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of CCN2 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of CCN2 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of CCN2 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of CCN2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CCN2 mRNA]
CTD PMID:31646340 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Fulvestrant results in increased expression of CCN3 mRNA; Fulvestrant results in increased expression of CCN3 protein CTD PMID:15072547 PMID:18984771 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccn5 cellular communication network factor 5 multiple interactions
increases expression
ISO Cadmium inhibits the reaction [Fulvestrant results in increased expression of CCN5 mRNA]; Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CCN5 mRNA]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of CCN5 mRNA]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of CCN5 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CCN5 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CCN5 mRNA] CTD PMID:10944450 PMID:17872378 PMID:29389661 PMID:31646340 NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636
JBrowse link
G Ccna1 cyclin A1 multiple interactions ISO [CDK6 affects the susceptibility to fulvestrant] which affects the expression of CCNA1 protein CTD PMID:24169358 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of CCNA2 mRNA; fulvestrant promotes the reaction [RB1 protein binds to CCNA2 promoter]; fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]; RB1 mutant form inhibits the reaction [fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]]
Fulvestrant results in decreased expression of CCNA2 mRNA; Fulvestrant results in decreased expression of CCNA2 protein
CTD PMID:15072547 PMID:19016759 PMID:21367843 PMID:31646340 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression
increases expression
ISO
EXP
fulvestrant inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]
fulvestrant results in decreased expression of CCNB1 mRNA
fulvestrant results in increased expression of CCNB1 mRNA
CTD PMID:12154049 PMID:17445807 PMID:21980073 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 multiple interactions
decreases expression
ISO
EXP
[Fulvestrant co-treated with Sirolimus] results in decreased expression of CCNB2 mRNA; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of CCNB2 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of CCNB2 mRNA]
fulvestrant results in decreased expression of CCNB2 mRNA
CTD PMID:19016759 PMID:21980073 PMID:31646340 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
[Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] inhibits the reaction [Estradiol results in increased expression of CCND1 protein]; arsenite inhibits the reaction [Fulvestrant results in decreased expression of CCND1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in decreased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [2,4-dihydroxybenzophenone results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [2,4-dihydroxybenzophenone results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [cyhalothrin affects the expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [cypermethrin results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [cyprodinil results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [FGF2 protein results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [fludioxonil results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [Methoxychlor results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCND1 protein]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [Triclosan results in increased expression of CCND1 mRNA]
Fulvestrant results in decreased expression of CCND1 mRNA; Fulvestrant results in decreased expression of CCND1 protein
fulvestrant results in decreased expression of CCND1 mRNA
Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of CCND1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Fulvestrant co-treated with bisphenol A] results in decreased expression of CCND1 mRNA]; [Fulvestrant co-treated with bisphenol A] results in decreased expression of CCND1 mRNA; Fulvestrant inhibits the reaction [Estradiol affects the expression of CCND1 mRNA]; GPER1 protein affects the reaction [[Fulvestrant co-treated with bisphenol A] results in decreased expression of CCND1 mRNA]; RTKI cpd inhibits the reaction [[Fulvestrant co-treated with bisphenol A] results in decreased expression of CCND1 mRNA]
CTD PMID:9094091 PMID:9705214 PMID:19361625 PMID:20179196 PMID:20206645 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estradiol affects the expression of CCND3 mRNA]
fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of CCND3 mRNA]; fulvestrant inhibits the reaction [Cadmium results in increased expression of CCND3 mRNA]
CTD PMID:9094091 PMID:24236210 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of CCNE1 mRNA
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased expression of CCNE1 protein]]; [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with Fulvestrant] inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [cyprodinil results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [fludioxonil results in increased expression of CCNE1 protein]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CCNE1 protein]
CTD PMID:20215421 PMID:26344002 PMID:27539251 PMID:28808208 PMID:33484789 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of CCNE2 mRNA
[fulvestrant co-treated with Sirolimus] results in decreased expression of CCNE2 mRNA
CTD PMID:19016759 PMID:31646340 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 increases expression ISO fulvestrant results in increased expression of CCNG2 mRNA CTD PMID:26865669 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cd24 CD24 molecule increases expression ISO fulvestrant results in increased expression of CD24 mRNA CTD PMID:16514628 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions
ISO fulvestrant results in increased expression of CD36 protein
Tamoxifen inhibits the reaction [fulvestrant results in increased expression of CD36 protein]
CTD PMID:27358406 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
decreases expression
ISO fulvestrant inhibits the reaction [Genistein results in increased expression of CD44 mRNA]
fulvestrant results in decreased expression of CD44 mRNA
CTD PMID:22553218 PMID:26865669 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD86 protein]] CTD PMID:21538406 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of CDC20 mRNA
fulvestrant results in decreased expression of CDC20 mRNA
CTD PMID:19016759 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25b cell division cycle 25B multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of CDC25B protein] CTD PMID:20208560 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [AG 1879 co-treated with Fulvestrant] inhibits the reaction [Chlorpyrifos results in decreased expression of and affects the localization of CDH1 protein]; Fulvestrant inhibits the reaction [2,4-dihydroxybenzophenone results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [[afimoxifene co-treated with EGF protein] results in increased expression of CDH1 protein]; Fulvestrant inhibits the reaction [afimoxifene results in increased expression of CDH1 protein]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of CDH1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CDH1 protein]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of CDH1 protein]; Fulvestrant inhibits the reaction [Chlorpyrifos results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [fludioxonil results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [nonylphenol results in decreased expression of CDH1 protein]; Fulvestrant inhibits the reaction [Triclosan results in decreased expression of CDH1 protein] CTD PMID:19593637 PMID:25690688 PMID:26407941 PMID:27145024 PMID:27539251 More... NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO fulvestrant inhibits the reaction [2,4-dihydroxybenzophenone results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [bisphenol F results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [fludioxonil results in increased expression of CDH2 protein]; fulvestrant inhibits the reaction [Triclosan results in increased expression of CDH2 protein] CTD PMID:27145024 PMID:27539251 PMID:28284859 PMID:28808208 PMID:28844962 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
ISO [Fulvestrant co-treated with Sirolimus] results in decreased expression of CDK1 mRNA; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of CDK1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of CDK1 mRNA] CTD PMID:19016759 PMID:31646340 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk12 cyclin-dependent kinase 12 affects response to substance ISO CDK12 affects the susceptibility to fulvestrant CTD PMID:19651820 NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression
multiple interactions
ISO fulvestrant results in increased expression of CDK2 mRNA
fulvestrant inhibits the reaction [DDT results in increased phosphorylation of and results in increased activity of CDK2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of CDK2 protein]
CTD PMID:9049186 PMID:20215421 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of CDK4 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CDK4 protein] CTD PMID:19361625 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 affects response to substance
increases expression
multiple interactions
ISO CDK6 affects the susceptibility to fulvestrant
fulvestrant results in increased expression of CDK6 protein
[CDK6 affects the susceptibility to fulvestrant] which affects the expression of CCNA1 protein; [CDK6 affects the susceptibility to fulvestrant] which affects the phosphorylation of RB1 protein
CTD PMID:24169358 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
affects response to substance
increases expression
ISO fulvestrant inhibits the reaction [ESR1 protein binds to CDKN1A promoter]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of CDKN1A protein]; fulvestrant inhibits the reaction [fludioxonil results in decreased expression of CDKN1A protein]; fulvestrant inhibits the reaction [Methoxychlor results in decreased expression of CDKN1A mRNA]; fulvestrant inhibits the reaction [Triclosan results in decreased expression of CDKN1A mRNA]
CDKN1A affects the susceptibility to fulvestrant
fulvestrant results in increased expression of CDKN1A mRNA
CTD PMID:12154049 PMID:12473173 PMID:15870704 PMID:20696891 PMID:24169358 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO [Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of CDKN1B protein; Fulvestrant inhibits the reaction [Estradiol results in increased degradation of CDKN1B protein]
fulvestrant results in increased expression of CDKN1B protein
CTD PMID:17283133 PMID:21367843 PMID:23029392 PMID:33484789 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP fulvestrant results in increased expression of CEBPD mRNA CTD PMID:21980073 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cenpa centromere protein A decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of CENPA mRNA
Cadmium inhibits the reaction [Fulvestrant results in decreased expression of CENPA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CENPA mRNA]
CTD PMID:16514628 PMID:31646340 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions ISO fulvestrant inhibits the reaction [bifenthrin results in increased secretion of CGA protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CGA protein]; fulvestrant inhibits the reaction [Zearalenone results in increased expression of CGA protein] CTD PMID:19580841 PMID:24938463 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of CHEK2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of CHEK2 protein] CTD PMID:23788033 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein] CTD PMID:26220752 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Fulvestrant results in increased expression of CITED2 mRNA] CTD PMID:31646340 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Ckb creatine kinase B multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CKB mRNA]
Fulvestrant results in increased expression of CKB mRNA
CTD PMID:31646340 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO fulvestrant results in increased expression of CLK1 mRNA CTD PMID:12154049 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clmn calmin increases expression ISO fulvestrant results in increased expression of CLMN mRNA CTD PMID:26865669 NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272
JBrowse link
G Clstn1 calsyntenin 1 decreases expression ISO fulvestrant results in decreased expression of CLSTN1 mRNA CTD PMID:16514628 NCBI chr 5:160,031,235...160,094,585
Ensembl chr 5:160,031,308...160,094,583
JBrowse link
G Clu clusterin multiple interactions EXP
ISO
fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of CLU mRNA]
fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [Doxorubicin results in increased expression of CLU mRNA]]
CTD PMID:16639590 PMID:26320837 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein increases expression ISO fulvestrant results in increased expression of CNBP mRNA CTD PMID:12154049 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in increased expression of COL1A1 mRNA] CTD PMID:27025157 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in increased expression of COL3A1 mRNA] CTD PMID:27025157 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of COMT mRNA]; Fulvestrant inhibits the reaction [butylbenzyl phthalate results in decreased expression of COMT mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of COMT mRNA]; Fulvestrant inhibits the reaction [daidzein results in decreased expression of COMT mRNA]; Fulvestrant inhibits the reaction [Dibutyl Phthalate results in decreased expression of COMT mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of COMT mRNA]; Fulvestrant inhibits the reaction [Genistein results in decreased expression of COMT mRNA]
Fulvestrant results in increased expression of COMT mRNA
CTD PMID:18192686 PMID:18497090 PMID:24040167 PMID:31646340 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Copb2 COPI coat complex subunit beta 2 decreases expression ISO fulvestrant results in decreased expression of COPB2 mRNA CTD PMID:16514628 NCBI chr 8:99,161,324...99,183,452 JBrowse link
G Crb2 crumbs cell polarity complex component 2 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of CRB2 mRNA
Cadmium inhibits the reaction [Fulvestrant results in increased expression of CRB2 mRNA]
CTD PMID:31646340 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294
JBrowse link
G Crebbp CREB binding protein multiple interactions EXP
ISO
fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]
fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [CREBBP protein binds to IL6 promoter]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]]
CTD PMID:18511507 PMID:24771768 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO fulvestrant results in increased expression of CSF1 mRNA CTD PMID:12154049 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD86 protein]]; fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein]] CTD PMID:21538406 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression ISO fulvestrant results in decreased expression of CSF3 mRNA CTD PMID:16298037 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csta cystatin A decreases expression ISO fulvestrant results in decreased expression of CSTA mRNA CTD PMID:15072547 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Ctbp1 C-terminal binding protein 1 decreases expression ISO Fulvestrant results in decreased expression of CTBP1 mRNA CTD PMID:31646340 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO fulvestrant inhibits the reaction [dioscin results in increased expression of CTNNB1 mRNA]
[AG 1879 co-treated with Fulvestrant] inhibits the reaction [Chlorpyrifos results in decreased expression of and affects the localization of CTNNB1 protein]; Fulvestrant inhibits the reaction [Chlorpyrifos results in decreased expression of CTNNB1 protein]
CTD PMID:24742230 PMID:32956863 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B multiple interactions ISO fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of CTSB protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSB protein]; fulvestrant inhibits the reaction [Triclosan results in increased expression of CTSB protein] CTD PMID:23219593 PMID:28844962 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D increases expression
decreases expression
multiple interactions
ISO fulvestrant results in increased expression of CTSD mRNA
fulvestrant results in decreased expression of CTSD mRNA
Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [Benzo(a)pyrene analog results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [Benzo(a)pyrene results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [ESR1 protein binds to CTSD promoter]]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of CTSD protein]; Fulvestrant inhibits the reaction [cyprodinil results in increased expression of CTSD protein]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSD protein]; Fulvestrant inhibits the reaction [Eucalyptol results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [fludioxonil results in increased expression of CTSD protein]; Fulvestrant inhibits the reaction [lavender oil results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [Limonene results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [linalool results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of CTSD protein]; Fulvestrant inhibits the reaction [nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of CTSD protein]; Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [Triclosan results in increased expression of CTSD protein]
CTD PMID:14750165 PMID:15072547 PMID:19365803 PMID:19654927 PMID:23219593 More... NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsh cathepsin H increases expression ISO fulvestrant results in increased expression of CTSH mRNA CTD PMID:16514628 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ctso cathepsin O increases expression
multiple interactions
ISO Fulvestrant results in increased expression of CTSO mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of CTSO mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of CTSO mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of CTSO mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of CTSO mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of CTSO mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CTSO mRNA]
CTD PMID:31646340 NCBI chr 2:167,230,407...167,254,761 JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP fulvestrant inhibits the reaction [resveratrol results in decreased expression of CXCL1 protein] CTD PMID:18277952 PMID:21192278 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO fulvestrant inhibits the reaction [bazedoxifene inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of CXCL10 mRNA]]; fulvestrant inhibits the reaction [Ospemifene inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]]
fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL10 mRNA]
CTD PMID:15557169 PMID:19533603 PMID:23943137 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL11 mRNA] CTD PMID:15557169 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression
ISO fulvestrant inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 mRNA]; fulvestrant inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CXCL12 protein]; fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of CXCL12 mRNA]; fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of CXCL12 mRNA]; fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased secretion of CXCL12 protein]; fulvestrant inhibits the reaction [CXCL12 protein results in increased expression of CXCL12 mRNA]; fulvestrant inhibits the reaction [CXCL12 protein results in increased expression of EB1 mRNA]; fulvestrant inhibits the reaction [CXCL12 protein results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCL12 protein]; fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 mRNA]; fulvestrant inhibits the reaction [Genistein results in increased expression of CXCL12 protein]
fulvestrant results in decreased expression of CXCL12 mRNA
CTD PMID:17872378 PMID:19584281 PMID:22549810 PMID:26435001 PMID:26865669 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of CXCL2 mRNA]]
fulvestrant inhibits the reaction [resveratrol results in decreased expression of CXCL2 protein]
CTD PMID:18277952 PMID:21192278 PMID:21501669 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of CXCL1 mRNA]] CTD PMID:21501669 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of CXCR4 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CXCR4 protein]; fulvestrant inhibits the reaction [Triclosan results in increased expression of CXCR4 protein] CTD PMID:28844962 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
ISO
EXP
fulvestrant inhibits the reaction [Diethylstilbestrol affects the localization of CYCS protein]; fulvestrant inhibits the reaction [Estradiol affects the localization of CYCS protein]; fulvestrant inhibits the reaction [Genistein affects the localization of CYCS protein]; fulvestrant inhibits the reaction [Tamoxifen affects the localization of CYCS protein]
fulvestrant inhibits the reaction [Estradiol results in increased expression of CYCS protein]
fulvestrant results in increased expression of CYCS mRNA
CTD PMID:15994367 PMID:16924424 PMID:20211987 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP
ISO
Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CYP11A1 mRNA]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]; Fulvestrant inhibits the reaction [FSHB protein results in increased expression of CYP11A1 protein]
fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased expression of CYP11A1 protein]]
CTD PMID:18511507 PMID:23209616 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO fulvestrant results in increased expression of CYP17A1 mRNA
fulvestrant inhibits the reaction [DDT results in increased expression of CYP17A1 mRNA]
CTD PMID:17158782 PMID:23684557 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO fulvestrant results in decreased activity of CYP19A1 protein
Fulvestrant results in increased expression of CYP19A1 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of CYP19A1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of CYP19A1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of CYP19A1 mRNA]; Fulvestrant inhibits the reaction [Dronabinol results in increased expression of CYP19A1 protein]
CTD PMID:11850205 PMID:15976552 PMID:31646340 PMID:32647869 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [Fulvestrant results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; Fulvestrant inhibits the reaction [daidzein results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1A1 protein]; Fulvestrant inhibits the reaction [Genistein results in decreased expression of CYP1A1 mRNA]; Fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1A1 promoter]]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [formononetin results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
fulvestrant inhibits the reaction [Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]]
Fulvestrant results in increased expression of CYP1A1 mRNA
CTD PMID:10619402 PMID:12093619 PMID:19460354 PMID:19901195 PMID:21513769 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1B1 mRNA]; fulvestrant inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]; fulvestrant inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1B1 mRNA]; fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]; fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; fulvestrant promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
fulvestrant results in increased expression of CYP1B1 mRNA
CTD PMID:16280380 PMID:19460354 PMID:20093341 PMID:21513769 PMID:28985473 More... NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [Androstanols co-treated with fulvestrant] inhibits the reaction [DDT results in increased expression of CYP2B10 mRNA] CTD PMID:23684557 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP fulvestrant results in increased expression of CYP2C11 mRNA CTD PMID:16837770 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP2C29 mRNA]; fulvestrant inhibits the reaction [Methoxychlor results in increased expression of CYP2C29 mRNA] CTD PMID:16280380
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP2E1 mRNA] CTD PMID:29362861 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP fulvestrant results in increased expression of CYP3A2 mRNA CTD PMID:16837770 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddx21 DExD-box helicase 21 decreases expression ISO fulvestrant results in decreased expression of DDX21 mRNA CTD PMID:16514628 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Ddx3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 decreases expression ISO Fulvestrant results in decreased expression of DDX3Y mRNA CTD PMID:16514628 NCBI chr  Y:1,115,095...1,135,754
Ensembl chr  Y:1,116,309...1,135,706
JBrowse link
G Dek DEK proto-oncogene multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of DEK protein] CTD PMID:23071688 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Depp1 DEPP1, autophagy regulator decreases expression ISO fulvestrant results in decreased expression of DEPP1 mRNA CTD PMID:16298037 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dhh desert hedgehog signaling molecule multiple interactions EXP fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of DHH mRNA] CTD PMID:17109907 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO fulvestrant results in decreased expression of DHX9 mRNA CTD PMID:16514628 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions ISO fulvestrant inhibits the reaction [cyhalothrin results in increased expression of DLG4 protein] CTD PMID:26969072 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression
multiple interactions
ISO
EXP
fulvestrant results in increased expression of DMBT1 mRNA
fulvestrant inhibits the reaction [Estrone results in increased expression of DMBT1 mRNA]
CTD PMID:15564322 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO fulvestrant results in decreased expression of DNAJA1 mRNA CTD PMID:16514628 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of DNMT1 mRNA
Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT1 mRNA]
fulvestrant results in decreased expression of DNMT1 mRNA
CTD PMID:19016759 PMID:22131059 PMID:30892605 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT3A mRNA] CTD PMID:22131059 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT3B mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT3B mRNA] CTD PMID:22131059 PMID:30892605 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dnmt3l DNA methyltransferase 3 like multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT3L mRNA] CTD PMID:22131059 NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Dst dystonin increases expression ISO fulvestrant results in increased expression of DST mRNA CTD PMID:16202921 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dynll1 dynein light chain LC8-type 1 increases expression ISO fulvestrant results in increased expression of DYNLL1 mRNA CTD PMID:12154049 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 increases expression ISO fulvestrant results in increased expression of DYRK2 mRNA CTD PMID:26865669 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of E2F1 mRNA
fulvestrant inhibits the reaction [DDT results in increased expression of E2F1 mRNA]
CTD PMID:20215421 PMID:23684557 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Ebag9 estrogen receptor binding site associated, antigen, 9 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [Cadmium results in increased expression of EBAG9 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of EBAG9 mRNA]
Fulvestrant results in decreased expression of EBAG9 mRNA
CTD PMID:31646340 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Ece1 endothelin converting enzyme 1 multiple interactions ISO [fulvestrant co-treated with Tamoxifen co-treated with ZD4054] results in decreased expression of ECE1 mRNA CTD PMID:19943105 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [fulvestrant co-treated with Tamoxifen co-treated with ZD4054] results in decreased expression of EDN1 mRNA CTD PMID:19943105 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO [fulvestrant co-treated with Tamoxifen co-treated with ZD4054] results in decreased expression of EDNRA mRNA CTD PMID:19943105 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Efna1 ephrin A1 increases expression ISO Fulvestrant results in increased expression of EFNA1 mRNA CTD PMID:15072547 PMID:26865669 PMID:31646340 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Efna5 ephrin A5 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of EFNA5 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of EFNA5 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of EFNA5 mRNA] CTD PMID:31646340 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
JBrowse link
G Egf epidermal growth factor affects activity
multiple interactions
ISO
EXP
fulvestrant affects the activity of EGF protein
fulvestrant inhibits the reaction [[afimoxifene co-treated with EGF protein] results in increased expression of CDH1 protein]; fulvestrant inhibits the reaction [EGF protein results in increased expression of PLAUR protein]; fulvestrant inhibits the reaction [EGF protein results in increased expression of TFF1 mRNA]
EGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]]
CTD PMID:19395996 PMID:19593637 PMID:20206645 PMID:25813982 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to AR protein]]; Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to ESR2 protein]]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of EGFR protein]; Fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of EGFR protein]; Fulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 PMID:29383186 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of EGR1 mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of EGR1 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of EGR1 mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of EGR1 protein] CTD PMID:25461906 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr3 early growth response 3 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of EGR3 mRNA
Cadmium inhibits the reaction [Fulvestrant results in decreased expression of EGR3 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of EGR3 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA]
CTD PMID:26865669 PMID:31646340 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases expression ISO fulvestrant results in decreased expression of EIF2S1 mRNA CTD PMID:16514628 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO fulvestrant results in decreased expression of EIF5 mRNA CTD PMID:16514628
G Elob elongin B decreases expression ISO fulvestrant results in decreased expression of ELOB mRNA CTD PMID:16514628 NCBI chr10:12,848,830...12,853,897
Ensembl chr10:12,848,827...12,853,635
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO fulvestrant results in decreased expression of ELOVL5 mRNA CTD PMID:16514628 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Epha1 Eph receptor A1 increases expression ISO fulvestrant results in increased expression of EPHA1 mRNA CTD PMID:12154049 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Epha4 Eph receptor A4 increases expression ISO fulvestrant results in increased expression of EPHA4 mRNA CTD PMID:26865669 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases expression
multiple interactions
affects response to substance
ISO Fulvestrant results in increased expression of ERBB2 mRNA
Fulvestrant inhibits the reaction [arsenite results in decreased expression of ERBB2 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of ERBB2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of ERBB2 mRNA]
ERBB2 affects the susceptibility to fulvestrant
CTD PMID:15072547 PMID:24169358 PMID:31646340 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of and results in increased phosphorylation of ERBB3 protein]
Fulvestrant results in decreased expression of ERBB3 mRNA
CTD PMID:31059536 PMID:31646340 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Ereg epiregulin multiple interactions EXP fulvestrant inhibits the reaction [Estradiol results in decreased expression of EREG mRNA] CTD PMID:23209616 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of ESPL1 mRNA
[fulvestrant co-treated with Sirolimus] results in decreased expression of ESPL1 mRNA
CTD PMID:19016759 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Esr1 estrogen receptor 1 affects expression
increases expression
increases ubiquitination
multiple interactions
decreases expression
affects response to substance
affects binding
affects activity
increases degradation
decreases activity
ISO
EXP
fulvestrant affects the expression of ESR1 mRNA
Fulvestrant results in increased expression of ESR1 mRNA
fulvestrant results in increased ubiquitination of ESR1 protein
5-OH-BDE-47 promotes the reaction [Fulvestrant results in decreased expression of ESR1 protein]; 6-OH-BDE-47 promotes the reaction [Fulvestrant results in decreased expression of ESR1 protein]; [Estradiol co-treated with Fulvestrant co-treated with ESR1 protein] results in increased expression of KCNH1 mRNA; [Fulvestrant binds to and results in decreased activity of ESR1 protein] inhibits the reaction [Drugs, Chinese Herbal results in increased activity of ESR1 protein]; [Fulvestrant binds to and results in decreased activity of ESR1 protein] inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; [Fulvestrant binds to and results in decreased activity of ESR1 protein] inhibits the reaction [icaritin results in increased activity of ESR1 protein]; [Fulvestrant binds to and results in decreased activity of ESR1 protein] inhibits the reaction [Quercetin results in increased activity of ESR1 protein]; [Fulvestrant binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Equol; [Fulvestrant binds to and results in decreased activity of ESR1 protein] which results in decreased susceptibility to Genistein; [Fulvestrant binds to and results in increased activity of ESR1 protein] which results in increased expression of HSPB1 mRNA; [Fulvestrant co-treated with ESR1 protein] results in increased expression of KCNH1 mRNA; [Fulvestrant results in decreased expression of ESR1 protein] which results in decreased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; AG 1879 inhibits the reaction [Fulvestrant promotes the reaction [ESR1 protein binds to IGF1R protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fulvestrant results in decreased expression of ESR1 protein]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA]; Curcumin inhibits the reaction [Fulvestrant results in increased degradation of ESR1 protein]; Fulvestrant affects the folding of and affects the activity of ESR1 protein; Fulvestrant binds to and results in decreased activity of ESR1 protein; Fulvestrant inhibits the reaction [1,1-bis(4-hydroxyphenyl)cyclohexane results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [16 alpha-iodoestradiol binds to ESR1 protein]; Fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ESR1 protein]; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [4,4'-bisphenol F results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of and results in increased phosphorylation of ESR1 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [4-hydroxystilbene analog binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [[6-(1,1-dimethylallyl)naringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[8-prenylnaringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with ESR1 protein] results in increased phosphorylation of AKT1 protein]; Fulvestrant inhibits the reaction [[Coumestrol binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[Estradiol binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased expression of NOS3 mRNA]; Fulvestrant inhibits the reaction [[fenarimol co-treated with Estradiol] results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[naringenin binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein]; Fulvestrant inhibits the reaction [Androstane-3,17-diol analog binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Androstane-3,17-diol binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Androstenols results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [benz(a)anthracene promotes the reaction [Estradiol results in increased activity of ESR1 protein]]; Fulvestrant inhibits the reaction [Benzo(a)pyrene promotes the reaction [Estradiol results in increased activity of ESR1 protein]]; Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [ESR1 protein binds to CTSD promoter]]; Fulvestrant inhibits the reaction [bisphenol A results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol B results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [butylparaben results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [Coumestrol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Diethylstilbestrol binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Dithiothreitol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Equilin results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [ESR1 protein binds to CDKN1A promoter]; Fulvestrant inhibits the reaction [ESR1 protein binds to STUB1 protein]; Fulvestrant inhibits the reaction [ESR1 protein results in increased susceptibility to Resveratrol]; Fulvestrant inhibits the reaction [Estradiol affects the localization of ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [Estriol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Estrone results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [exemestane binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [fenarimol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [fluoranthene promotes the reaction [Estradiol results in increased activity of ESR1 protein]]; Fulvestrant inhibits the reaction [Genistein results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [glyphosate results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [luteolin-7-O-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR1 protein]]; Fulvestrant inhibits the reaction [Methylcholanthrene results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]]; Fulvestrant inhibits the reaction [o,p'-DDT results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [prochloraz results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [propylparaben results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Resveratrol analog binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Resveratrol binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Resveratrol promotes the reaction [ESR1 protein binds to BMP2 promoter]]; Fulvestrant inhibits the reaction [Tartrazine results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Testosterone results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1A1 promoter]]; Fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to HSD3B gene]]]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]]; Fulvestrant promotes the reaction [5-OH-BDE-47 affects the expression of ESR1 protein]; Fulvestrant promotes the reaction [6-OH-BDE-47 affects the expression of ESR1 protein]; Fulvestrant promotes the reaction [ESR1 protein binds to ESR1 protein]; Fulvestrant promotes the reaction [ESR1 protein binds to ESR2 protein]; Fulvestrant promotes the reaction [ESR1 protein binds to IGF1R protein]; Fulvestrant promotes the reaction [Estradiol results in decreased expression of ESR1 protein]; Fulvestrant promotes the reaction [Hexachlorobenzene results in decreased expression of ESR1 protein]; Fulvestrant results in decreased activity of and results in decreased expression of ESR1 protein; Fulvestrant results in increased degradation of and results in decreased expression of and results in decreased activity of ESR1 protein; KRT18 protein promotes the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]; KRT18 protein promotes the reaction [Fulvestrant results in increased degradation of ESR1 protein]; KRT8 protein promotes the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]; KRT8 protein promotes the reaction [Fulvestrant results in increased degradation of ESR1 protein]; RU 58668 promotes the reaction [Fulvestrant inhibits the reaction [Genistein results in increased activity of ESR1 protein]]; tyrphostin AG 1024 inhibits the reaction [Fulvestrant promotes the reaction [ESR1 protein binds to IGF1R protein]]
fulvestrant results in decreased expression of ESR1 protein
ESR1 protein mutant form affects the susceptibility to fulvestrant
fulvestrant binds to ESR1 protein
Fulvestrant results in decreased expression of ESR1; Fulvestrant results in decreased expression of ESR1 mRNA; Fulvestrant results in decreased expression of ESR1 protein
fulvestrant affects the activity of ESR1 protein
fulvestrant results in increased degradation of ESR1 protein
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Fulvestrant binds to and results in decreased activity of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fulvestrant results in increased degradation of ESR1 protein]; Fulvestrant binds to and results in decreased activity of ESR1 protein; Fulvestrant inhibits the reaction [[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A affects the expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A affects the expression of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of and affects the localization of ESR1 protein]; Fulvestrant inhibits the reaction [butylparaben results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in decreased expression of ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ESR1 protein]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to HSD3B gene]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]; Fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in decreased expression of ESR1 protein]; Fulvestrant inhibits the reaction [naringin results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [tributyltin affects the expression of ESR1 protein]
4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA]; [bisphenol A co-treated with Fulvestrant] results in increased expression of ESR1 mRNA; bisphenol A inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA]; Fulvestrant binds to and results in decreased activity of ESR1 protein; Fulvestrant binds to and results in increased activity of ESR1 protein mutant form; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [[notoginsenoside R1 co-treated with Lipopolysaccharides] results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [cyhalothrin results in increased expression of ESR1]; Fulvestrant inhibits the reaction [Diarylheptanoids binds to and affects the transport of ESR1 protein]; Fulvestrant inhibits the reaction [Diethylstilbestrol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [dioscin results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Fulvestrant inhibits the reaction [Estradiol binds to and affects the transport of ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [Estrogens results in increased expression of ESR1 protein]; Fulvestrant inhibits the reaction [octylphenol results in increased activity of ESR1 protein]; Fulvestrant inhibits the reaction [tributyltin results in decreased expression of ESR1 protein]; Fulvestrant promotes the reaction [bisphenol A results in decreased expression of ESR1 protein]; Fulvestrant promotes the reaction [Estradiol results in increased expression of ESR1 protein]
fulvestrant results in increased degradation of ESR1 mRNA; fulvestrant results in increased degradation of ESR1 protein
fulvestrant results in decreased activity of ESR1 protein
CTD PMID:9048584 PMID:11174852 PMID:11518614 PMID:11867264 PMID:12441364 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases response to substance
increases expression
decreases expression
affects binding
affects expression
multiple interactions
ISO
EXP
ESR2 protein results in increased susceptibility to fulvestrant
Fulvestrant results in increased expression of ESR2 mRNA; Fulvestrant results in increased expression of ESR2 protein
fulvestrant results in decreased expression of ESR2 mRNA alternative form
fulvestrant binds to ESR2 protein
fulvestrant affects the expression of ESR2 protein
fulvestrant binds to and results in decreased activity of ESR2 protein; fulvestrant inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]; fulvestrant inhibits the reaction [[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR2 mRNA]; fulvestrant inhibits the reaction [naringin results in increased expression of ESR2 mRNA]
Estradiol inhibits the reaction [Fulvestrant results in decreased expression of ESR2 mRNA alternative form]; Fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [dioscin results in increased expression of ESR2 protein]; Fulvestrant inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Fulvestrant inhibits the reaction [Estrogens results in increased activity of ESR2 protein polymorphism]; Fulvestrant inhibits the reaction [sodium arsenite results in increased expression of ESR2 mRNA]; Fulvestrant inhibits the reaction [sodium arsenite results in increased expression of ESR2 protein]
fulvestrant results in decreased expression of ESR2 protein
6-OH-BDE-47 promotes the reaction [Fulvestrant results in decreased expression of ESR2 protein]; Fulvestrant binds to and results in decreased activity of ESR2 protein; Fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ESR2 protein]; Fulvestrant inhibits the reaction [3,3',4,5'-tetrahydroxystilbene results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [[Estradiol co-treated with ESR2 protein] results in increased expression of NOS3 mRNA]; Fulvestrant inhibits the reaction [Androstane-3,17-diol analog binds to and results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [Androstane-3,17-diol binds to and results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to ESR2 protein]]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of ESR2 mRNA]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of ESR2 protein]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of ESR2 mRNA]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [diarylpropionitrile results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [Dihydrotestosterone results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [Dihydrotestosterone results in increased localization of ESR2 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of ESR2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR2 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased localization of ESR2 protein]; Fulvestrant inhibits the reaction [Genistein results in increased expression of ESR2 protein]; Fulvestrant inhibits the reaction [luteolin-7-O-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of ESR2 protein]]; Fulvestrant inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]; Fulvestrant inhibits the reaction [Plant Preparations results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [prochloraz results in decreased expression of ESR2 mRNA]; Fulvestrant inhibits the reaction [Resveratrol results in increased activity of ESR2 protein]; Fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein]; Fulvestrant promotes the reaction [5-OH-BDE-47 results in decreased expression of ESR2 protein]; Fulvestrant promotes the reaction [6-OH-BDE-47 affects the expression of ESR2 protein]; Fulvestrant promotes the reaction [ESR1 protein binds to ESR2 protein]
CTD PMID:9048584 PMID:14742696 PMID:15103026 PMID:15130599 PMID:15171712 More... NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G Esrra estrogen related receptor, alpha multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Fulvestrant results in increased expression of ESRRA mRNA]; AG 1879 inhibits the reaction [Fulvestrant results in increased expression of ESRRA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of ESRRA mRNA]; Fulvestrant promotes the reaction [SP1 protein binds to ESRRA promoter]; Fulvestrant promotes the reaction [SP3 protein binds to ESRRA promoter]; GPER1 protein promotes the reaction [Fulvestrant results in increased expression of ESRRA mRNA]; Pertussis Toxin inhibits the reaction [Fulvestrant results in increased expression of ESRRA mRNA]
fulvestrant results in increased expression of ESRRA mRNA; fulvestrant results in increased expression of ESRRA protein
CTD PMID:15968320 PMID:20211987 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G F11r F11 receptor multiple interactions ISO Fulvestrant inhibits the reaction [diarylpropionitrile results in increased expression of F11R mRNA]; Fulvestrant inhibits the reaction [diarylpropionitrile results in increased expression of F11R protein]; Fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of F11R mRNA]; Fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of F11R protein] CTD PMID:19433574 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
JBrowse link
G F2r coagulation factor II (thrombin) receptor increases expression ISO fulvestrant results in increased expression of F2R mRNA CTD PMID:12154049 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of FABP4 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of FABP4 protein]
fulvestrant inhibits the reaction [bisphenol A glucuronide results in increased expression of FABP4 protein]; fulvestrant inhibits the reaction [Diosgenin results in decreased expression of FABP4 mRNA]
CTD PMID:24418828 PMID:26018136 PMID:26408789 PMID:27003841 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions ISO fulvestrant inhibits the reaction [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] CTD PMID:19576517 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fam102a family with sequence similarity 102, member A multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of FAM102A mRNA] CTD PMID:14605097 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643
JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 multiple interactions ISO Fulvestrant inhibits the reaction [afimoxifene results in increased expression of FARP1 mRNA] CTD PMID:16849584 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
JBrowse link
G Faslg Fas ligand decreases expression
increases expression
ISO fulvestrant results in decreased expression of FASLG mRNA
[fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of FASLG mRNA
CTD PMID:20145137 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO fulvestrant inhibits the reaction [Norethynodrel results in increased activity of FASN protein] CTD PMID:15870863 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo5 F-box protein 5 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of FBXO5 mRNA
fulvestrant results in decreased expression of FBXO5 mRNA
CTD PMID:19016759 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fgf18 fibroblast growth factor 18 multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol A results in increased expression of FGF18 mRNA] CTD PMID:30892605 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [FGF2 protein results in increased expression of CCND1 protein]
fulvestrant inhibits the reaction [naringin results in increased expression of FGF2 mRNA]
CTD PMID:20179196 PMID:23596885 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf9 fibroblast growth factor 9 decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of FGF9 mRNA
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of FGF9 mRNA]
CTD PMID:14602803 PMID:30892605 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fhl2 four and a half LIM domains 2 decreases expression ISO fulvestrant results in decreased expression of FHL2 mRNA CTD PMID:26865669 NCBI chr 9:45,388,979...45,462,530
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 mRNA; [Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 protein; [fulvestrant co-treated with Bucladesine] results in increased methylation of FKBP5 intron; bisphenol A promotes the reaction [[fulvestrant co-treated with Bucladesine] results in increased methylation of FKBP5 intron]; Estradiol inhibits the reaction [[Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 mRNA] CTD PMID:26427651 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fkbpl FKBP prolyl isomerase like increases response to substance ISO FKBPL protein results in increased susceptibility to fulvestrant CTD PMID:20103631 NCBI chr20:4,099,845...4,101,315
Ensembl chr20:4,099,806...4,101,368
JBrowse link
G Flg filaggrin multiple interactions ISO fulvestrant affects the reaction [bisphenol A affects the expression of FLG mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of FLG mRNA] CTD PMID:28701262 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Flnc filamin C decreases expression ISO fulvestrant results in decreased expression of FLNC mRNA CTD PMID:16514628 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of FOS mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of FOS mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of FOS mRNA]; Fulvestrant inhibits the reaction [Atrazine results in increased expression of FOS protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of FOS mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of FOS mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of FOS protein]; Fulvestrant inhibits the reaction [luteolin-7-O-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FOS protein]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]; [Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of FOS mRNA]; Fulvestrant inhibits the reaction [DDT results in increased expression of FOS mRNA]; GPER1 protein affects the reaction [[Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]; RTKI cpd inhibits the reaction [[Fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]
fulvestrant results in decreased expression of FOS mRNA
CTD PMID:10478842 PMID:15072547 PMID:17125913 PMID:20875696 PMID:21813366 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxa1 forkhead box A1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [arsenite results in decreased expression of FOXA1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of FOXA1 mRNA]
Fulvestrant results in increased expression of FOXA1 mRNA
CTD PMID:31646340 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxc1 forkhead box C1 decreases expression ISO fulvestrant results in decreased expression of FOXC1 mRNA CTD PMID:26865669 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
JBrowse link
G Foxm1 forkhead box M1 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of FOXM1 mRNA
Fulvestrant results in decreased expression of FOXM1 mRNA; Fulvestrant results in decreased expression of FOXM1 protein
CTD PMID:19016759 PMID:20208560 PMID:31646340 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of FOXO3 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of FOXO3 mRNA] CTD PMID:30682495 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp3 forkhead box P3 increases expression
multiple interactions
ISO fulvestrant results in increased expression of FOXP3 mRNA
TGFB1 protein promotes the reaction [fulvestrant results in increased expression of FOXP3 mRNA]
CTD PMID:20145137 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP
ISO
Fulvestrant inhibits the reaction [[Estradiol co-treated with FSHB protein] results in increased stability of and results in increased expression of TGFBR3 mRNA]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to HSD3B gene]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]; Fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]; Fulvestrant inhibits the reaction [FSHB protein results in increased abundance of Cyclic AMP]; Fulvestrant inhibits the reaction [FSHB protein results in increased expression of CYP11A1 protein]; Fulvestrant inhibits the reaction [FSHB protein results in increased expression of HSD3B protein]
fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to HSD3B gene]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased expression of CYP11A1 protein]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased expression of HSD3B protein]]
CTD PMID:15878966 PMID:18511507 PMID:25549949 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fst follistatin increases expression
multiple interactions
ISO Fulvestrant results in increased expression of FST mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of FST mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of FST mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of FST mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of FST mRNA]
CTD PMID:16298037 PMID:31646340 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Fyttd1 forty-two-three domain containing 1 decreases expression ISO fulvestrant results in decreased expression of FYTTD1 mRNA CTD PMID:16514628 NCBI chr11:67,877,967...67,907,565
Ensembl chr11:67,877,967...67,907,511
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of G6PDX mRNA]
Fulvestrant results in increased expression of G6PD mRNA
CTD PMID:10433208 PMID:31646340 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha increases expression ISO fulvestrant results in increased expression of GABPA mRNA CTD PMID:12154049 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of GAS6 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of GAS6 mRNA]; fulvestrant inhibits the reaction [Tamoxifen results in increased expression of GAS6 mRNA] CTD PMID:19429434 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gch1 GTP cyclohydrolase 1 multiple interactions EXP fulvestrant inhibits the reaction [resveratrol results in increased expression of GCH1 protein] CTD PMID:17666920 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein] CTD PMID:24437944 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of GH1 protein]; Fulvestrant inhibits the reaction [4-nonylphenol results in increased secretion of GH1 protein]; Fulvestrant inhibits the reaction [4-octylphenol results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of GH1 protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of GH1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of GH1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased secretion of GH1 protein] CTD PMID:19145065 PMID:19463694 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of GJA1 mRNA; fulvestrant results in decreased expression of GJA1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fulvestrant results in decreased expression of GJA1 protein]; Fulvestrant promotes the reaction [NEDD4 protein binds to and results in increased ubiquitination of GJA1 protein]; MAP2K3 promotes the reaction [Fulvestrant results in decreased expression of GJA1 protein]; MAP2K6 promotes the reaction [Fulvestrant results in decreased expression of GJA1 protein]; SB 203580 inhibits the reaction [Fulvestrant promotes the reaction [NEDD4 protein binds to and results in increased ubiquitination of GJA1 protein]]; SB 203580 inhibits the reaction [Fulvestrant results in decreased expression of GJA1 mRNA]; SB 203580 inhibits the reaction [Fulvestrant results in decreased expression of GJA1 protein]
CTD PMID:29180066 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gjb2 gap junction protein, beta 2 multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of GJB2 mRNA] CTD PMID:30187510 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in decreased expression of GLB1 protein] CTD PMID:17075048 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
JBrowse link
G Gli1 GLI family zinc finger 1 increases expression EXP fulvestrant results in increased expression of GLI1 mRNA CTD PMID:20232216 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gnaq G protein subunit alpha q multiple interactions EXP fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of GNAQ protein]] CTD PMID:23419388 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions
decreases expression
ISO fulvestrant affects the reaction [2,3',4,4',5-pentachlorobiphenyl affects the expression of GNRH1 protein]; fulvestrant affects the reaction [2,4,4',5-tetrachlorobiphenyl affects the expression of GNRH1 protein]; fulvestrant affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of GNRH1 protein]; fulvestrant inhibits the reaction [Chlorpyrifos results in increased secretion of GNRH1 protein]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of GNRH1 mRNA]; fulvestrant inhibits the reaction [Methoxychlor results in increased secretion of GNRH1 protein]
fulvestrant results in decreased expression of GNRH1 protein
CTD PMID:10537130 PMID:12088877 PMID:19362103 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Golga5 golgin A5 decreases expression ISO fulvestrant results in decreased expression of GOLGA5 mRNA CTD PMID:16514628 NCBI chr 6:121,612,389...121,640,552
Ensembl chr 6:121,612,529...121,640,413
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
increases expression
decreases response to substance
affects response to substance
ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [Fulvestrant results in increased expression of GPER1 mRNA]; [Fulvestrant co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] inhibits the reaction [bisphenol A results in increased expression of GPER1 mRNA]; [Fulvestrant co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] inhibits the reaction [Estradiol results in increased expression of GPER1 mRNA]; [Fulvestrant co-treated with 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline] inhibits the reaction [Estradiol results in increased expression of GPER1 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of GPER1 protein]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of GPER1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of GPER1 protein]; GPER1 protein affects the reaction [Fulvestrant promotes the reaction [CAPN1 protein results in increased cleavage of and results in increased activity of CAPN1 protein]]; GPER1 protein promotes the reaction [Fulvestrant results in increased expression of ESRRA mRNA]
GPER1 protein affects the reaction [[fulvestrant co-treated with bisphenol A] results in decreased expression of CCND1 mRNA]; GPER1 protein affects the reaction [[fulvestrant co-treated with bisphenol A] results in increased expression of FOS mRNA]
Fulvestrant results in increased expression of GPER1 mRNA; Fulvestrant results in increased expression of GPER1 protein
GPER1 mutant form results in decreased susceptibility to fulvestrant
GPER1 protein affects the susceptibility to fulvestrant
CTD PMID:20211987 PMID:24169358 PMID:24440569 PMID:25969534 PMID:27880919 More... NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
decreases expression
decreases response to substance
ISO Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [alpha-terpineol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Apigenin results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Arsenic Trioxide results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [butylparaben metabolite results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [chrysin results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Cyproterone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Eucalyptol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [isobutylparaben metabolite results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [isobutylparaben results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [kaempferol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [lavender oil results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Limonene results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [linalool results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Lynestrenol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Megestrol Acetate results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Mifepristone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Norethindrone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [oxybenzone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Resveratrol results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Spironolactone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of GREB1 mRNA]
Fulvestrant results in decreased expression of GREB1 mRNA
GREB1 mutant form results in decreased susceptibility to fulvestrant
CTD PMID:20846786 PMID:22558281 PMID:24169358 PMID:29389661 PMID:29945225 More... NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of GRIN1 protein]; fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased phosphorylation of GRIN1 protein] CTD PMID:21763338 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of GRIN2B protein]; fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased phosphorylation of GRIN2B protein] CTD PMID:20858508 PMID:21763338 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP
ISO
fulvestrant inhibits the reaction [gypenoside analog results in increased phosphorylation of GSK3B protein]; fulvestrant inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]
CTD PMID:23170834 PMID:24726523 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gzmb granzyme B increases expression
decreases expression
ISO [fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of GZMB mRNA
fulvestrant results in decreased expression of GZMB mRNA; fulvestrant results in decreased expression of GZMB protein
CTD PMID:20145137 NCBI chr15:30,343,361...30,346,792 JBrowse link
G H2ax H2A.X variant histone multiple interactions EXP
ISO
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of H2AX protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of H2AX protein]
Fulvestrant inhibits the reaction [Estradiol results in increased expression of H2AX protein modified form]; Fulvestrant inhibits the reaction [oxybenzone results in increased expression of H2AX protein modified form]; Fulvestrant inhibits the reaction [propylparaben results in increased expression of H2AX protein modified form]
CTD PMID:23788033 PMID:31939680 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2az1 H2A.Z variant histone 1 decreases expression ISO Fulvestrant results in decreased expression of H2AZ1 mRNA CTD PMID:20543978 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression ISO fulvestrant results in decreased expression of HMGB1 mRNA CTD PMID:16514628 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO
EXP
fulvestrant results in decreased expression of HMOX1 mRNA
fulvestrant inhibits the reaction [gypenoside analog results in increased expression of and results in increased activity of HMOX1 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; fulvestrant inhibits the reaction [Phytoestrogens results in increased expression of and results in increased activity of HMOX1 protein]; fulvestrant inhibits the reaction [resveratrol results in increased expression of HMOX1 protein]
fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]
CTD PMID:16298037 PMID:19781563 PMID:21192278 PMID:24437944 PMID:24726523 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1b HNF1 homeobox B decreases expression ISO Fulvestrant results in decreased expression of HNF1B mRNA CTD PMID:32623698 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in decreased expression of HNF4A mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA] CTD PMID:23184660 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO fulvestrant results in decreased expression of HNRNPA2B1 mRNA CTD PMID:16514628 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO fulvestrant results in decreased expression of HNRNPH1 mRNA CTD PMID:16514628 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U decreases expression ISO fulvestrant results in decreased expression of HNRNPU mRNA CTD PMID:16514628 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Hoxa10 homeobox A10 multiple interactions
increases expression
ISO 4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of HOXA10 mRNA]; [Fulvestrant co-treated with 4-tert-octylphenol] results in decreased expression of HOXA10 mRNA; [Fulvestrant co-treated with bisphenol A] results in decreased expression of HOXA10 mRNA; bisphenol A inhibits the reaction [Fulvestrant results in increased expression of HOXA10 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of HOXA10 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of HOXA10 mRNA] CTD PMID:30061528
G Hoxa13 homeo box A13 multiple interactions ISO fulvestrant inhibits the reaction [Genistein results in decreased expression of HOXA13 mRNA] CTD PMID:21810550 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091
JBrowse link
G Hoxa9 homeobox A9 multiple interactions ISO fulvestrant inhibits the reaction [Genistein results in decreased expression of HOXA9 mRNA] CTD PMID:21810550 NCBI chr 4:81,323,235...81,329,344 JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of HSF1 mRNA] CTD PMID:12927369 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of HSP90AA1 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of HSP90AA1 protein]
Fulvestrant results in increased expression of HSP90AA1 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of HSP90AA1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of HSP90AA1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of HSP90AA1 mRNA]
CTD PMID:11568360 PMID:31646340 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO fulvestrant results in decreased expression of HSP90AB1 mRNA CTD PMID:16514628 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of HSP90B1 mRNA
fulvestrant inhibits the reaction [bisphenol A results in increased expression of HSP90B1 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of HSP90B1 protein]
CTD PMID:11568360 PMID:16514628 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of HSPA1B mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of HSPA1B mRNA] CTD PMID:12927369 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO fulvestrant results in decreased expression of HSPA4 mRNA CTD PMID:16514628 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Chlordecone co-treated with fulvestrant] results in increased expression of HSPA5 protein CTD PMID:17640991 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO fulvestrant results in decreased expression of HSPA8 mRNA CTD PMID:16514628 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [fulvestrant binds to and results in increased activity of ESR1 protein] which results in increased expression of HSPB1 mRNA; fulvestrant inhibits the reaction [Estradiol results in increased expression of HSPB1 mRNA] CTD PMID:11174852 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO fulvestrant results in decreased expression of HSPD1 mRNA CTD PMID:16514628 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of ICAM1 mRNA]]
fulvestrant inhibits the reaction [resveratrol results in decreased expression of ICAM1 protein]
CTD PMID:18277952 PMID:21192278 PMID:21501669 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icam5 intercellular adhesion molecule 5 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in decreased expression of ICAM5 mRNA] CTD PMID:26789235 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of ID1 mRNA] CTD PMID:20031206 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO fulvestrant results in increased expression of ID3 mRNA CTD PMID:26865669 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO Fulvestrant inhibits the reaction [afimoxifene results in increased expression of IER3 mRNA] CTD PMID:16849584 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO fulvestrant results in decreased expression of IFRD1 mRNA CTD PMID:16514628 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP fulvestrant inhibits the reaction [naringin results in increased expression of IGF1 mRNA] CTD PMID:23596885 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions
increases phosphorylation
ISO
EXP
AG 1879 inhibits the reaction [fulvestrant promotes the reaction [ESR1 protein binds to IGF1R protein]]; fulvestrant inhibits the reaction [[Hexachlorobenzene co-treated with Estradiol] results in increased expression of IGF1R protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of IGF1R mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of IGF1R mRNA]; fulvestrant inhibits the reaction [Hexachlorobenzene results in increased expression of IGF1R protein]; fulvestrant promotes the reaction [ESR1 protein binds to IGF1R protein]; tyrphostin AG 1024 inhibits the reaction [fulvestrant promotes the reaction [ESR1 protein binds to IGF1R protein]]
fulvestrant inhibits the reaction [[Triclosan co-treated with Ethinyl Estradiol] results in increased expression of IGF1R mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of IGF1R mRNA]
fulvestrant results in increased phosphorylation of IGF1R protein
CTD PMID:19815064 PMID:19879930 PMID:23261820 PMID:23810794 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions EXP
ISO
fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in decreased expression of BAD protein modified form]]; fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased cleavage of and results in increased activity of CASP3 protein]]; fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of BCL2L1 protein]]; fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of GNAQ protein]]; fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of IGF2R protein]]; fulvestrant inhibits the reaction [dan-shen root extract results in decreased susceptibility to IGF2 protein mutant form]
Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of and affects the localization of NFATC4 protein]]; Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of NPPA protein]]; Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of NPPB protein]]; Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of PPP3CA protein]]
CTD PMID:23419388 PMID:32415908 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions ISO
EXP
fulvestrant inhibits the reaction [bisphenol A results in decreased methylation of IGF2R gene]
fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein mutant form results in increased expression of IGF2R protein]]
CTD PMID:22131059 PMID:23419388 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of IGFBP1 mRNA
Fulvestrant inhibits the reaction [arsenite results in decreased expression of IGFBP1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of IGFBP1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of IGFBP1 mRNA]
CTD PMID:31646340 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of IGFBP4 mRNA
Fulvestrant inhibits the reaction [arsenite results in increased expression of IGFBP4 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of IGFBP4 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of IGFBP4 mRNA]
CTD PMID:15072547 PMID:31646340 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of IGFBP5 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of IGFBP5 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of IGFBP5 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of IGFBP5 mRNA]
CTD PMID:31646340 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Ihh Indian hedgehog signaling molecule multiple interactions
decreases expression
EXP fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of IHH mRNA]
fulvestrant results in decreased expression of IHH mRNA
CTD PMID:17109907 PMID:20232216 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein] CTD PMID:26220752 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions ISO fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein] CTD PMID:25128825 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A multiple interactions ISO fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of IL17A protein]] CTD PMID:21501669 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17rb interleukin 17 receptor B multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of IL17RB mRNA
fulvestrant results in decreased expression of IL17RB mRNA
CTD PMID:19016759 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] CTD PMID:17850464 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; fulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]] CTD PMID:10614622 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO
EXP
fulvestrant results in increased expression of IL1B mRNA
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]
fulvestrant inhibits the reaction [bisphenol A results in increased expression of IL1B mRNA]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of IL1B mRNA]]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of IL1B mRNA]]
fulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]]
CTD PMID:16298037 PMID:20600708 PMID:21501669 PMID:23943137 PMID:25738436 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il24 interleukin 24 increases expression ISO fulvestrant results in increased expression of IL24 mRNA CTD PMID:16298037 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il4 interleukin 4 multiple interactions ISO fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD86 protein]]; fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein]] CTD PMID:21538406 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
fulvestrant results in increased expression of IL6 mRNA
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [resveratrol results in decreased expression of IL6 protein]
fulvestrant inhibits the reaction [bazedoxifene inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased secretion of IL6 protein]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; fulvestrant inhibits the reaction [Ospemifene inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]]; fulvestrant inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]
Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [CREBBP protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOA2 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOA3 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOR2 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NMNAT1 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [RCOR1 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [RELA protein modified form binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [SIRT1 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]
CTD PMID:16298037 PMID:18277952 PMID:19533603 PMID:21192278 PMID:21501669 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains decreases expression ISO Fulvestrant results in decreased expression of ILRUN mRNA CTD PMID:16514628 NCBI chr20:5,809,931...5,876,231
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Ins2 insulin 2 multiple interactions ISO fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of INS2 protein]; fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of INS2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of INS2 protein]
Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [INS protein results in increased uptake of Glucose]]; Fulvestrant inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; PPARG protein affects the reaction [Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [INS protein results in increased uptake of Glucose]]]
CTD PMID:18446233 PMID:26944108 PMID:28180948 PMID:32623698 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insr insulin receptor multiple interactions EXP fulvestrant inhibits the reaction [resveratrol results in increased phosphorylation of INSR protein] CTD PMID:18426865 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 decreases expression ISO fulvestrant results in decreased expression of IQGAP1 mRNA CTD PMID:16514628 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of IRS1 mRNA
Fulvestrant inhibits the reaction [[Hexachlorobenzene co-treated with Estradiol] results in increased phosphorylation of IRS1 protein]; Fulvestrant inhibits the reaction [arsenite results in increased expression of IRS1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of IRS1 mRNA]; Fulvestrant inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of IRS1 protein]
CTD PMID:15072547 PMID:19879930 PMID:31646340 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itgam integrin subunit alpha M decreases expression ISO fulvestrant results in decreased expression of ITGAM protein CTD PMID:28811679 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgax integrin subunit alpha X decreases expression ISO fulvestrant results in decreased expression of ITGAX protein CTD PMID:28811679 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression
multiple interactions
ISO fulvestrant results in increased expression of ITGB1 mRNA
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of ITGB1 protein]; Fulvestrant promotes the reaction [bisphenol A results in increased expression of ITGB1 protein]
CTD PMID:12154049 PMID:25534675 PMID:30611077 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Ivl involucrin multiple interactions ISO fulvestrant affects the reaction [bisphenol A affects the expression of IVL mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of IVL mRNA] CTD PMID:28701262 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jak2 Janus kinase 2 decreases expression
decreases phosphorylation
multiple interactions
ISO fulvestrant results in decreased expression of JAK2 mRNA
Fulvestrant results in decreased phosphorylation of JAK2 protein
Fulvestrant inhibits the reaction [bisphenol F results in increased phosphorylation of JAK2 protein]
CTD PMID:26865669 PMID:32044397 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of JUN mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of JUN mRNA]
fulvestrant results in increased expression of JUN mRNA
CTD PMID:12154049 PMID:17125913 PMID:30682495 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Cadmium inhibits the reaction [Fulvestrant results in increased expression of JUNB mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of JUNB mRNA] CTD PMID:31646340 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 multiple interactions
decreases expression
ISO [Estradiol co-treated with fulvestrant co-treated with ESR1 protein] results in increased expression of KCNH1 mRNA; [fulvestrant co-treated with ESR1 protein] results in increased expression of KCNH1 mRNA; fulvestrant inhibits the reaction [Estradiol results in increased expression of KCNH1 mRNA]
fulvestrant results in decreased expression of KCNH1 mRNA
CTD PMID:19351862 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions EXP fulvestrant inhibits the reaction [Estradiol results in decreased expression of KCNMA1 mRNA alternative form]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of KCNMA1 mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of KCNMA1 protein] CTD PMID:16102753 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Fulvestrant results in decreased expression of KIF20A mRNA CTD PMID:16514628 PMID:31646340 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions EXP fulvestrant inhibits the reaction [Estradiol results in increased expression of KLF4 protein] CTD PMID:21484412 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Kmt5a lysine methyltransferase 5A multiple interactions ISO [fulvestrant results in increased susceptibility to bisphenol A] which results in decreased expression of KMT5A mRNA; fulvestrant inhibits the reaction [bisphenol A results in decreased expression of KMT5A mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of KMT5A mRNA] CTD PMID:27114721 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression ISO fulvestrant results in decreased expression of KPNA2 mRNA CTD PMID:16514628 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression ISO fulvestrant results in decreased expression of KPNB1 mRNA CTD PMID:16514628 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt1 keratin 1 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A affects the expression of KRT1 mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of KRT1 mRNA] CTD PMID:28701262 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt10 keratin 10 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A affects the expression of KRT10 mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of KRT10 mRNA] CTD PMID:28701262 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt13 keratin 13 multiple interactions ISO Fulvestrant inhibits the reaction [afimoxifene results in increased expression of KRT13 mRNA] CTD PMID:16849584 NCBI chr10:85,052,122...85,056,032
Ensembl chr10:85,051,889...85,056,084
JBrowse link
G Krt18 keratin 18 multiple interactions ISO KRT18 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]; KRT18 protein promotes the reaction [fulvestrant results in increased degradation of ESR1 protein] CTD PMID:20061804 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 multiple interactions ISO KRT8 protein promotes the reaction [fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR1 protein]]; KRT8 protein promotes the reaction [fulvestrant results in increased degradation of ESR1 protein] CTD PMID:20061804 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Kynu kynureninase increases expression ISO fulvestrant results in increased expression of KYNU mRNA CTD PMID:26865669 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G L1cam L1 cell adhesion molecule increases expression ISO Fulvestrant results in increased expression of L1CAM mRNA CTD PMID:31646340 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lefty1 left right determination factor 1 multiple interactions ISO fulvestrant inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of LEFTY1 mRNA]] CTD PMID:25136773 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
JBrowse link
G Lgals1 galectin 1 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of LGALS1 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of LGALS1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of LGALS1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of LGALS1 mRNA]
CTD PMID:31646340 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of LIF mRNA
Fulvestrant promotes the reaction [Estradiol results in decreased expression of LIF mRNA]
CTD PMID:30061528 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lpl lipoprotein lipase multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [bisphenol A glucuronide results in increased expression of LPL protein]; Fulvestrant inhibits the reaction [ESR1 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Fulvestrant inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of LPL mRNA]
Fulvestrant results in decreased expression of LPL mRNA
fulvestrant results in decreased expression of LPL mRNA
CTD PMID:17974624 PMID:26018136 PMID:31646340 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp5 LDL receptor related protein 5 multiple interactions ISO fulvestrant inhibits the reaction [dioscin results in increased expression of LRP5 mRNA] CTD PMID:24742230 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 multiple interactions
decreases expression
ISO arsenite inhibits the reaction [Fulvestrant results in decreased expression of LTBP1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of LTBP1 mRNA] CTD PMID:31646340 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Ltf lactotransferrin multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of LTF mRNA]; Fulvestrant inhibits the reaction [Chlordecone results in increased expression of LTF mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of LTF mRNA]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of LTF mRNA]
Fulvestrant results in increased expression of LTF mRNA
Fulvestrant inhibits the reaction [arsenite results in decreased expression of LTF mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of LTF mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of LTF mRNA]
CTD PMID:9607801 PMID:10433208 PMID:17640991 PMID:19654927 PMID:31646340 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Ly75 lymphocyte antigen 75 multiple interactions ISO fulvestrant inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of LY75 protein]] CTD PMID:21538406 NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of MAD2L1 mRNA
fulvestrant results in decreased expression of MAD2L1 mRNA
CTD PMID:19016759 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions
increases expression
ISO Estradiol inhibits the reaction [Fulvestrant results in increased expression of MAFF mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of MAFF mRNA] CTD PMID:31646340 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor multiple interactions ISO fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of MANF mRNA]; fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MANF mRNA] CTD PMID:16467188 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 multiple interactions ISO MAP2K3 promotes the reaction [fulvestrant results in decreased expression of GJA1 protein] CTD PMID:29180066 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO MAP2K6 promotes the reaction [fulvestrant results in decreased expression of GJA1 protein] CTD PMID:29180066 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases expression ISO fulvestrant results in increased expression of MAP3K11 mRNA CTD PMID:12154049 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
[U 0126 results in decreased phosphorylation of [MAPK3 protein co-treated with MAPK1 protein]] which results in decreased susceptibility to Fulvestrant; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAPK1 protein modified form]; Fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Dibutyl Phthalate] results in decreased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Atrazine results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased activity of MAPK1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MAPK1 protein modified form]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased activity of MAPK1 protein]; Fulvestrant inhibits the reaction [luteolin-7-O-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK1 protein]]; Fulvestrant inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of MAPK1 protein]
fulvestrant results in increased phosphorylation of MAPK1 protein
[Estradiol co-treated with Fulvestrant] results in increased phosphorylation of MAPK1 protein; Fulvestrant inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Estriol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Promegestone results in increased phosphorylation of MAPK1 protein]
Fulvestrant affects the reaction [sodium arsenite affects the expression of MAPK1 mRNA]; Fulvestrant affects the reaction [sodium arsenite affects the expression of MAPK1 protein]; Fulvestrant inhibits the reaction [4-nonylphenol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased activity of MAPK1 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [octylphenol results in increased phosphorylation of MAPK1 protein]; Fulvestrant promotes the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]
CTD PMID:14710592 PMID:15319301 PMID:15531431 PMID:16020483 PMID:16951259 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
[U 0126 results in decreased phosphorylation of [MAPK3 protein co-treated with MAPK1 protein]] which results in decreased susceptibility to Fulvestrant; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAPK3 protein modified form]; Fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Dibutyl Phthalate] results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Atrazine results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MAPK3 protein modified form]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [luteolin-7-O-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
fulvestrant results in increased phosphorylation of MAPK3 protein
fulvestrant inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Promegestone results in increased phosphorylation of MAPK3 protein]
Fulvestrant affects the reaction [sodium arsenite affects the expression of MAPK3 mRNA]; Fulvestrant affects the reaction [sodium arsenite affects the expression of MAPK3 protein]; Fulvestrant inhibits the reaction [4-nonylphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [octylphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant promotes the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]
CTD PMID:15319301 PMID:15531431 PMID:16020483 PMID:17125913 PMID:17689939 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO fulvestrant results in decreased expression of MAPT protein CTD PMID:20579400 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Matr3 matrin 3 decreases expression ISO fulvestrant results in decreased expression of MATR3 mRNA CTD PMID:16514628 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166
JBrowse link
G Mbp myelin basic protein multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in decreased expression of MBP protein] CTD PMID:27364615 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Med1 mediator complex subunit 1 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of MED1 mRNA
Fulvestrant inhibits the reaction [arsenite results in increased expression of MED1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of MED1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MED1 mRNA]
CTD PMID:31646340 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mgp matrix Gla protein decreases expression ISO fulvestrant results in decreased expression of MGP mRNA CTD PMID:16514628 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 decreases expression ISO fulvestrant results in decreased expression of MICAL2 mRNA CTD PMID:26865669 NCBI chr 1:166,345,853...166,471,715
NCBI chr 1:166,491,721...166,530,575
Ensembl chr 1:166,345,859...166,471,719
JBrowse link
G Mir21 microRNA 21 multiple interactions
increases expression
ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [fulvestrant results in increased expression of MIR21 mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of MIR21 mRNA]; fulvestrant inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA]; fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA] CTD PMID:19264808 PMID:23052036 PMID:25969534 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir30d microRNA 30d decreases expression ISO fulvestrant results in decreased expression of MIR30D mRNA CTD PMID:27481218 NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of MKI67 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of MKI67 protein]
fulvestrant inhibits the reaction [bisphenol A results in decreased expression of MKI67 mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of MKI67 mRNA]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of MKI67 mRNA]
CTD PMID:19654927 PMID:27260121 PMID:28701262 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mme membrane metallo-endopeptidase increases expression ISO fulvestrant results in increased expression of MME mRNA CTD PMID:16202921 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]] CTD PMID:20600708 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression ISO fulvestrant results in increased expression of MMP15 mRNA CTD PMID:15072547 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [AG 1879 co-treated with Fulvestrant] inhibits the reaction [Chlorpyrifos results in increased expression of MMP2 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of MMP2 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of MMP2 protein]; Fulvestrant inhibits the reaction [Chlorpyrifos results in increased expression of MMP2 protein]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MMP2 mRNA]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MMP2 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of MMP2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of MMP2 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MMP2 protein]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of MMP2 protein]; Fulvestrant inhibits the reaction [Triclosan results in increased expression of MMP2 protein] CTD PMID:19956873 PMID:26407941 PMID:28390675 PMID:28844962 PMID:32956863 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MMP9 protein]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of MMP9 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MMP9 protein]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of MMP9 protein]; Fulvestrant inhibits the reaction [Triclosan results in increased expression of MMP9 protein]
Fulvestrant results in increased expression of MMP9 mRNA
CTD PMID:19956873 PMID:25534675 PMID:25690688 PMID:28390675 PMID:28844962 More... NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Fulvestrant inhibits the reaction [Resveratrol results in decreased activity of MPO protein]; Fulvestrant inhibits the reaction [Resveratrol results in decreased expression of MPO protein] CTD PMID:18277952 PMID:21192278 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mta1 metastasis associated 1 decreases expression ISO Fulvestrant results in decreased expression of MTA1 mRNA CTD PMID:31646340 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases response to substance
multiple interactions
ISO MTOR results in decreased susceptibility to fulvestrant
[Sirolimus results in decreased activity of MTOR protein] which results in increased susceptibility to fulvestrant; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MTOR protein]
CTD PMID:19016759 PMID:23000059 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions
increases expression
ISO bisphenol A inhibits the reaction [Fulvestrant results in increased expression of MUC1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MUC1 mRNA]; Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of MUC1 mRNA]
Fulvestrant results in increased expression of MUC1 mRNA; Fulvestrant results in increased expression of MUC1 protein
CTD PMID:30061528 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO fulvestrant results in decreased expression of MYB mRNA CTD PMID:26865669 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Mybl1 MYB proto-oncogene like 1 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of MYBL1 mRNA
Fulvestrant inhibits the reaction [Apigenin results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [chrysin results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Cyproterone results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [kaempferol results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Lynestrenol results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Norethindrone results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [oxybenzone results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased expression of MYBL1 mRNA]; Fulvestrant inhibits the reaction [Spironolactone results in increased expression of MYBL1 mRNA]
CTD PMID:26865669 PMID:33405908 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
ISO
EXP
fulvestrant inhibits the reaction [DDT results in increased expression of MYC mRNA]
Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of MYC mRNA]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of MYC mRNA]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of MYC protein]; Fulvestrant inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein]; Fulvestrant inhibits the reaction [arsenite results in increased expression of MYC mRNA]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of MYC mRNA]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of MYC protein]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of MYC mRNA]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of MYC mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MYC mRNA]
fulvestrant results in decreased expression of MYC mRNA
Fulvestrant results in decreased expression of MYC mRNA; Fulvestrant results in decreased expression of MYC protein
CTD PMID:15072547 PMID:19654927 PMID:20219890 PMID:21980073 PMID:23684557 More... NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh10 myosin heavy chain 10 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of MYH10 protein]; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MYH10 protein] CTD PMID:16901965 NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165
JBrowse link
G Myog myogenin multiple interactions ISO fulvestrant inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYOG protein] CTD PMID:24431215 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Nab2 Ngfi-A binding protein 2 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of NAB2 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of NAB2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of NAB2 mRNA] CTD PMID:31646340 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989
JBrowse link
G Nanog Nanog homeobox increases expression ISO fulvestrant results in increased expression of NANOG protein CTD PMID:27581495 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO Fulvestrant results in decreased expression of NARS1 mRNA CTD PMID:16514628 NCBI chr18:57,989,308...58,005,639
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO fulvestrant results in decreased expression of NCAPH mRNA CTD PMID:16514628 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncl nucleolin decreases expression ISO fulvestrant results in decreased expression of NCL mRNA CTD PMID:16514628 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions
increases expression
ISO
EXP
fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]]
Fulvestrant results in increased expression of NCOA1 mRNA
fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]
CTD PMID:18511507 PMID:31646340 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [NCOA2 protein binds to IL6 promoter]]
Fulvestrant results in increased expression of NCOA2 mRNA
CTD PMID:24771768 PMID:31646340 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [NCOA3 protein binds to IL6 promoter]]
Fulvestrant results in increased expression of NCOA3 mRNA
CTD PMID:24771768 PMID:31646340 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of NCOR1 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of NCOR1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of NCOR1 mRNA]; Fulvestrant promotes the reaction [NCOR1 protein binds to TFF2 promoter] CTD PMID:20696891 PMID:31646340 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of NCOR2 mRNA]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOR2 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of NCOR2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of NCOR2 mRNA] CTD PMID:24771768 PMID:31646340 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of NDC80 mRNA
[fulvestrant co-treated with Sirolimus] results in decreased expression of NDC80 mRNA
CTD PMID:19016759 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase multiple interactions ISO fulvestrant promotes the reaction [NEDD4 protein binds to and results in increased ubiquitination of GJA1 protein]; SB 203580 inhibits the reaction [fulvestrant promotes the reaction [NEDD4 protein binds to and results in increased ubiquitination of GJA1 protein]] CTD PMID:29180066 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nefh neurofilament heavy chain multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in decreased expression of NEFH protein] CTD PMID:27364615 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nek2 NIMA-related kinase 2 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of NEK2 mRNA
fulvestrant results in decreased expression of NEK2 mRNA
CTD PMID:19016759 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions ISO Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of and affects the localization of NFATC4 protein]] CTD PMID:32415908 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [ginsenoside Rb1 results in increased localization of NFE2L2 protein]
fulvestrant inhibits the reaction [gypenoside analog affects the localization of NFE2L2 protein]; fulvestrant inhibits the reaction [Phytoestrogens affects the localization of NFE2L2 protein]
CTD PMID:19781563 PMID:24726523 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression
multiple interactions
ISO fulvestrant results in decreased expression of NFKBIA mRNA
fulvestrant inhibits the reaction [bisphenol A results in decreased expression of NFKBIA protein]
fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]]
CTD PMID:16298037 PMID:23170834 PMID:27522653 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of NKX3-1 mRNA]
fulvestrant inhibits the reaction [Genistein results in decreased expression of NKX3-1 mRNA]
CTD PMID:17131305 PMID:21810550 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of NME1 mRNA
fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of NME1 mRNA]; fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NME1 mRNA]
fulvestrant results in decreased expression of NME1 mRNA
CTD PMID:16467188 PMID:19016759 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 multiple interactions ISO fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [NMNAT1 protein binds to IL6 promoter]] CTD PMID:24771768 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 decreases expression ISO fulvestrant results in decreased expression of NMRK1 mRNA CTD PMID:26865669 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of NOS2 mRNA]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of NOS2 protein]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
Fulvestrant inhibits the reaction [Estradiol results in increased expression of NOS2 protein]; Fulvestrant inhibits the reaction [Resveratrol results in increased activity of NOS2 protein]; Fulvestrant inhibits the reaction [sannoshashinto affects the expression of NOS2]
CTD PMID:11583108 PMID:12860292 PMID:15256495 PMID:17666920 PMID:23615023 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
ISO
EXP
[fulvestrant co-treated with MK-886] inhibits the reaction [resveratrol results in increased expression of NOS3 mRNA]; fulvestrant inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased expression of NOS3 mRNA]; fulvestrant inhibits the reaction [[Estradiol co-treated with ESR2 protein] results in increased expression of NOS3 mRNA]; fulvestrant inhibits the reaction [[puerarin results in increased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]; fulvestrant inhibits the reaction [amurensin G results in increased phosphorylation of NOS3 protein]; fulvestrant inhibits the reaction [puerarin results in increased phosphorylation of NOS3 protein]
fulvestrant inhibits the reaction [Estradiol results in increased expression of NOS3 protein]
fulvestrant results in decreased expression of NOS3 protein
CTD PMID:11583108 PMID:14742696 PMID:19962728 PMID:21791144 PMID:21884717 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO fulvestrant results in decreased expression of NPM1 mRNA CTD PMID:16514628 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP
ISO
fulvestrant inhibits the reaction [[Estradiol co-treated with Phenylephrine] results in increased expression of NPPA protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of NPPA mRNA]
Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of NPPA protein]]
CTD PMID:14718400 PMID:32415908 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of NPPB protein]] CTD PMID:32415908 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppc natriuretic peptide C multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of NPPC mRNA] CTD PMID:9435603 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein] CTD PMID:24437944 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of NR0B1 mRNA
Fulvestrant inhibits the reaction [arsenite results in decreased expression of NR0B1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of NR0B1 mRNA]
CTD PMID:31646340 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
decreases expression
ISO arsenite inhibits the reaction [Fulvestrant results in decreased expression of NR0B2 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in decreased expression of NR0B2 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in decreased expression of NR0B2 mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of NR0B2 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of NR0B2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of NR0B2 mRNA] CTD PMID:31646340 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO fulvestrant inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein]
Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of NR1H4 mRNA]
CTD PMID:25257666 PMID:30245210 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO fulvestrant results in increased activity of NR1I2 protein CTD PMID:15885729 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of NR2F6 mRNA
Estradiol inhibits the reaction [Fulvestrant results in increased expression of NR2F6 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of NR2F6 mRNA]
CTD PMID:31646340 NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression
multiple interactions
ISO Fulvestrant results in increased expression of NR3C1 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of NR3C1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of NR3C1 mRNA]
CTD PMID:31646340 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO fulvestrant results in increased expression of NR4A1 mRNA CTD PMID:16514628 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO Fulvestrant results in increased expression of NR5A2 mRNA CTD PMID:31646340 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions ISO fulvestrant inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of NRF1 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA]; fulvestrant inhibits the reaction [resveratrol results in increased expression of NRF1 mRNA] CTD PMID:22105178 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO fulvestrant inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] CTD PMID:26502914 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of NRIP1 mRNA
Fulvestrant inhibits the reaction [arsenite results in increased expression of NRIP1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of NRIP1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of NRIP1 mRNA]
CTD PMID:31646340 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nrp1 neuropilin 1 multiple interactions
decreases expression
ISO Cadmium inhibits the reaction [Fulvestrant results in decreased expression of NRP1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of NRP1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of NRP1 mRNA] CTD PMID:31646340 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit decreases expression ISO fulvestrant results in decreased expression of NUS1 mRNA CTD PMID:16514628 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
JBrowse link
G Ocln occludin multiple interactions ISO
EXP
Fulvestrant inhibits the reaction [diarylpropionitrile results in increased expression of OCLN mRNA]; Fulvestrant inhibits the reaction [diarylpropionitrile results in increased expression of OCLN protein]; Fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of OCLN mRNA]; Fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of OCLN protein]
fulvestrant inhibits the reaction [estradiol 3-benzoate results in increased expression of OCLN mRNA]
CTD PMID:19433574 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Odc1 ornithine decarboxylase 1 affects expression EXP fulvestrant affects the expression of ODC1 mRNA CTD PMID:15925091 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Olfm1 olfactomedin 1 decreases expression ISO fulvestrant results in decreased expression of OLFM1 mRNA CTD PMID:26865669 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased cleavage of PARP1 protein]; fulvestrant inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein] CTD PMID:21732360 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax5 paired box 5 increases expression ISO fulvestrant results in increased expression of PAX5 mRNA CTD PMID:12154049 NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO fulvestrant results in decreased expression of PCLAF mRNA CTD PMID:16514628 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression
ISO 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [Estradiol results in increased expression of PCNA protein]]; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]]; [Fulvestrant co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in decreased expression of PCNA protein; [Fulvestrant co-treated with Sirolimus] results in decreased expression of PCNA mRNA; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PCNA protein]; Fulvestrant inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]; Fulvestrant promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of PCNA protein]]
fulvestrant results in decreased expression of PCNA mRNA
fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of PCNA mRNA]; fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PCNA mRNA]
CTD PMID:15072547 PMID:16202921 PMID:16467188 PMID:19016759 PMID:33484789 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of PDGFA mRNA]; fulvestrant inhibits the reaction [Cadmium results in increased expression of PDGFA mRNA] CTD PMID:17125913 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha multiple interactions ISO fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of PDGFRA protein]; fulvestrant inhibits the reaction [Cadmium results in increased phosphorylation of PDGFRA protein] CTD PMID:17125913 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdzk1 PDZ domain containing 1 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [arsenite results in increased expression of PDZK1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of PDZK1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PDZK1 mRNA]
Fulvestrant results in decreased expression of PDZK1 mRNA
CTD PMID:14605097 PMID:26865669 PMID:31646340 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514
JBrowse link
G Pelp1 proline, glutamate and leucine rich protein 1 decreases expression ISO Fulvestrant results in decreased expression of PELP1 mRNA CTD PMID:31646340 NCBI chr10:55,094,798...55,111,833
Ensembl chr10:55,094,796...55,111,994
JBrowse link
G Per1 period circadian regulator 1 multiple interactions EXP fulvestrant inhibits the reaction [Estradiol results in increased expression of PER1 mRNA] CTD PMID:17761890 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pgr progesterone receptor multiple interactions
decreases expression
ISO
EXP
Fulvestrant binds to and results in decreased activity of PGR protein; Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [4-hydroxy-equilenin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [alternariol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [arsenite results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol A analog results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [chromous chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [chromous chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [cobaltous chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [cobaltous chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [CXCL12 protein results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [desmethylicaritin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Diethylstilbestrol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Estrogens results in increased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [Estrone results in decreased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [gamma-terpinene results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [icariin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [icaritin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [isobavachin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [isobavachin results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [lead chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [lead chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Limonene results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [linalool results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Mercuric Chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Mercuric Chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Mycotoxins results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [nickel chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [nickel chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [pentabrominated diphenyl ether 100 results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Vanadates results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Vanadates results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [zearalenol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Zearalenone results in increased expression of PGR protein]
Fulvestrant results in decreased expression of PGR mRNA
fulvestrant inhibits the reaction [bisphenol A results in increased expression of PGR protein]; fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR protein]; fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of PGR mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of PGR protein]; fulvestrant inhibits the reaction [isobutylparaben results in increased expression of PGR protein]; fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in increased expression of PGR protein]
bisphenol A promotes the reaction [Fulvestrant results in decreased expression of PGR mRNA]; Estradiol promotes the reaction [Fulvestrant results in decreased expression of PGR mRNA]; Fulvestrant affects the reaction [Chlordecone results in increased expression of PGR mRNA]; Fulvestrant promotes the reaction [Estradiol results in decreased expression of PGR mRNA]
Fulvestrant results in decreased expression of PGR mRNA; Fulvestrant results in decreased expression of PGR protein
CTD PMID:9607801 PMID:10411312 PMID:11014213 PMID:11391616 PMID:11867264 More... NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phb2 prohibitin 2 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of PHB2 mRNA
Estradiol inhibits the reaction [Fulvestrant results in decreased expression of PHB2 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of PHB2 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of PHB2 mRNA]
CTD PMID:31646340 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression ISO fulvestrant results in increased expression of PIK3R3 mRNA CTD PMID:26865669 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO fulvestrant results in increased expression of PIM1 mRNA CTD PMID:16298037 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pitx1 paired-like homeodomain 1 multiple interactions ISO fulvestrant inhibits the reaction [Genistein results in decreased expression of PITX1 mRNA]; fulvestrant inhibits the reaction [Genistein results in increased expression of PITX1 mRNA] CTD PMID:21810550 PMID:22553218 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of and affects the localization of PKM protein]; Fulvestrant inhibits the reaction [Glucose promotes the reaction [Estradiol results in increased phosphorylation of PKM protein]] CTD PMID:28284859 PMID:32078667 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions
decreases expression
ISO fulvestrant inhibits the reaction [EGF protein results in increased expression of PLAUR protein]
fulvestrant results in decreased expression of PLAUR mRNA
CTD PMID:19395996 PMID:26865669 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 increases expression ISO fulvestrant results in increased expression of PLEKHF2 mRNA CTD PMID:26865669 NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO Fulvestrant inhibits the reaction [Estradiol results in increased expression of PLK1 protein]; Fulvestrant promotes the reaction [RB1 protein binds to PLK1 promoter]; Fulvestrant promotes the reaction [SIN3B protein binds to PLK1 promoter]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to PLK1 promoter]] CTD PMID:20208560 PMID:21367843 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Polr2b RNA polymerase II subunit B decreases expression ISO fulvestrant results in decreased expression of POLR2B mRNA CTD PMID:16514628 NCBI chr14:30,797,228...30,834,916
Ensembl chr14:30,797,228...30,834,916
JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP fulvestrant inhibits the reaction [nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]] CTD PMID:20837582 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of POU5F1 mRNA] CTD PMID:22132214 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO fulvestrant inhibits the reaction [Diethylstilbestrol results in increased activity of PPARG protein]; fulvestrant inhibits the reaction [Diosgenin results in decreased expression of PPARG mRNA]
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]; PPARG protein affects the reaction [Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [INS protein results in increased uptake of Glucose]]]
CTD PMID:22710028 PMID:26408789 PMID:32623698 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO
EXP
Fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to CYP11A1 gene]]; Fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to HSD3B gene]]; Fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]]
fulvestrant inhibits the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]
CTD PMID:18511507 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D decreases expression ISO fulvestrant results in decreased expression of PPM1D mRNA CTD PMID:16514628 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B multiple interactions EXP fulvestrant inhibits the reaction [Dinoprostone results in decreased expression of PPP1R9B protein] CTD PMID:23054057 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions ISO Fulvestrant inhibits the reaction [dan-shen root extract inhibits the reaction [IGF2 protein modified form results in increased expression of PPP3CA protein]] CTD PMID:32415908 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Fulvestrant results in decreased expression of PRC1 mRNA CTD PMID:31646340 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prf1 perforin 1 decreases expression
increases expression
ISO Fulvestrant results in decreased expression of PRF1 mRNA; Fulvestrant results in decreased expression of PRF1 protein
[fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of PRF1 mRNA
CTD PMID:20145137 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO fulvestrant results in decreased expression of PRKDC mRNA CTD PMID:16514628 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prl prolactin multiple interactions
decreases expression
decreases secretion
ISO
EXP
[fulvestrant co-treated with Estradiol] results in increased secretion of PRL protein
Fulvestrant results in decreased expression of PRL mRNA; Fulvestrant results in decreased expression of PRL protein
fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of and results in increased secretion of PRL protein]; fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [4-nonylphenol results in increased secretion of PRL protein]; fulvestrant inhibits the reaction [4-octylphenol results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of PRL protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased secretion of PRL protein]; fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [Cadmium results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of and results in increased secretion of PRL protein]
fulvestrant results in decreased secretion of PRL protein
CTD PMID:15950373 PMID:17909072 PMID:19463694 PMID:20419096 PMID:24236210 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prss23 serine protease 23 decreases expression ISO fulvestrant results in decreased expression of PRSS23 mRNA CTD PMID:26865669 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091
JBrowse link
G Psen1 presenilin 1 multiple interactions EXP fulvestrant inhibits the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein] CTD PMID:25461682 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 decreases expression ISO fulvestrant results in decreased expression of PSMD14 mRNA CTD PMID:16514628 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
JBrowse link
G Psmd6 proteasome 26S subunit, non-ATPase 6 decreases expression ISO fulvestrant results in decreased expression of PSMD6 mRNA CTD PMID:16514628 NCBI chr15:11,102,208...11,112,180
Ensembl chr15:11,102,180...11,205,620
JBrowse link
G Psme4 proteasome activator subunit 4 decreases expression ISO fulvestrant results in decreased expression of PSME4 mRNA CTD PMID:16514628 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
JBrowse link
G Ptch1 patched 1 multiple interactions
increases expression
EXP
ISO
fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of PTCH1 mRNA]
Fulvestrant results in increased expression of PTCH1 mRNA
CTD PMID:17109907 PMID:31646340 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Pten phosphatase and tensin homolog increases response to substance
multiple interactions
ISO PTEN protein results in increased susceptibility to fulvestrant
fulvestrant inhibits the reaction [Quercetin results in increased expression of PTEN protein]
CTD PMID:19435893 PMID:21732360 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions ISO fulvestrant inhibits the reaction [resveratrol inhibits the reaction [TNF protein results in increased expression of PTGER4 mRNA]] CTD PMID:24771768 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO fulvestrant results in decreased expression of PTGES mRNA CTD PMID:26865669 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [bisphenol F results in increased expression of PTGS2 mRNA]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of PTGS2 protein]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]
Fulvestrant results in increased expression of PTGS2 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of PTGS2 mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of PTGS2 mRNA]; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PTGS2 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of PTGS2 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of PTGS2 mRNA]; Fulvestrant inhibits the reaction [Hexachlorobenzene results in increased expression of PTGS2 protein]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; Fulvestrant promotes the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]
CTD PMID:15256495 PMID:20951759 PMID:21513769 PMID:26546977 PMID:31646340 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 increases degradation ISO fulvestrant results in increased degradation of PTK2 protein CTD PMID:24440569 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G multiple interactions ISO Fulvestrant inhibits the reaction [afimoxifene results in increased expression of PTPRG mRNA] CTD PMID:16849584 NCBI chr15:12,872,284...13,552,186
Ensembl chr15:12,871,721...13,554,094
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of PTTG1 mRNA
fulvestrant results in decreased expression of PTTG1 mRNA; fulvestrant results in decreased expression of PTTG1 protein
CTD PMID:18984771 PMID:19016759 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rab2a RAB2A, member RAS oncogene family increases expression ISO fulvestrant results in increased expression of RAB2A mRNA CTD PMID:12154049 NCBI chr 5:21,676,219...21,738,833
Ensembl chr 5:21,676,129...21,739,899
JBrowse link
G Rab30 RAB30, member RAS oncogene family multiple interactions ISO Fulvestrant inhibits the reaction [afimoxifene results in increased expression of RAB30 mRNA] CTD PMID:16849584 NCBI chr 1:146,803,652...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO fulvestrant results in decreased expression of RACGAP1 mRNA CTD PMID:16514628 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad51 RAD51 recombinase multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of RAD51 mRNA
fulvestrant results in decreased expression of RAD51 mRNA
CTD PMID:19016759 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rala RAS like proto-oncogene A multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of RALA mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of RALA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of RALA mRNA] CTD PMID:31646340 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases expression ISO fulvestrant results in decreased expression of RAP1A mRNA CTD PMID:16514628 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rapgefl1 Rap guanine nucleotide exchange factor like 1 decreases expression ISO fulvestrant results in decreased expression of RAPGEFL1 mRNA CTD PMID:26865669 NCBI chr10:83,793,711...83,810,373
Ensembl chr10:83,793,694...83,810,371
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of RARA mRNA
Fulvestrant inhibits the reaction [arsenite results in increased expression of RARA mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of RARA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of RARA mRNA]
CTD PMID:31646340 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarres2 retinoic acid receptor responder 2 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in decreased expression of and results in decreased secretion of RARRES2 protein]; fulvestrant inhibits the reaction [tetrabromobisphenol A results in decreased expression of and results in decreased secretion of RARRES2 protein]; fulvestrant inhibits the reaction [tetrachlorodian results in decreased expression of and results in decreased secretion of RARRES2 protein] CTD PMID:29653259 NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
ISO [CDK6 affects the susceptibility to Fulvestrant] which affects the phosphorylation of RB1 protein; Fulvestrant inhibits the reaction [bis(4-hydroxyphenyl)sulfone results in increased phosphorylation of RB1 protein]; Fulvestrant promotes the reaction [RB1 protein binds to CCNA2 promoter]; Fulvestrant promotes the reaction [RB1 protein binds to PLK1 promoter]; Fulvestrant promotes the reaction [RB1 protein binds to RNR2 promoter]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to PLK1 promoter]]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to RNR2 promoter]]
fulvestrant results in decreased phosphorylation of RB1 protein
CTD PMID:21367843 PMID:24169358 PMID:30684532 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor decreases expression ISO fulvestrant results in decreased expression of RBBP7 mRNA CTD PMID:16514628 NCBI chr  X:31,913,080...31,931,245
Ensembl chr  X:31,913,081...31,931,226
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease decreases expression ISO fulvestrant results in decreased expression of RBBP8 mRNA CTD PMID:26865669 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 decreases expression ISO fulvestrant results in decreased expression of RCL1 mRNA CTD PMID:26865669 NCBI chr 1:226,824,524...226,869,046
Ensembl chr 1:226,824,534...226,902,315
JBrowse link
G Rcor1 REST corepressor 1 multiple interactions ISO fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [RCOR1 protein binds to IL6 promoter]] CTD PMID:24771768 NCBI chr 6:130,069,606...130,146,164
Ensembl chr 6:130,069,392...130,146,153
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [RELA protein modified form binds to IL6 promoter]]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of RELA protein]; fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of RELA protein]
Fulvestrant inhibits the reaction [sodium arsenite results in increased expression of RELA mRNA]; Fulvestrant inhibits the reaction [sodium arsenite results in increased expression of RELA protein]
CTD PMID:24771768 PMID:27522653 PMID:28390675 PMID:30684567 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rerg RAS-like, estrogen-regulated, growth-inhibitor affects response to substance ISO RERG affects the susceptibility to fulvestrant CTD PMID:24169358 NCBI chr 4:169,981,634...170,089,777
Ensembl chr 4:169,982,279...170,089,715
JBrowse link
G Ret ret proto-oncogene decreases expression ISO fulvestrant results in decreased expression of RET mRNA CTD PMID:26865669 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Retn resistin multiple interactions ISO fulvestrant inhibits the reaction [octylphenol results in increased expression of RETN mRNA] CTD PMID:18417718 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 increases expression ISO fulvestrant results in increased expression of RHBDF1 mRNA CTD PMID:26865669 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763
JBrowse link
G Rnf4 ring finger protein 4 multiple interactions ISO fulvestrant inhibits the reaction [Diethylstilbestrol results in increased expression of RNF4 mRNA] CTD PMID:14749358 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
JBrowse link
G Rpl6 ribosomal protein L6 decreases expression ISO fulvestrant results in decreased expression of RPL6 mRNA CTD PMID:16514628 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 decreases expression ISO fulvestrant results in decreased expression of RRM1 mRNA CTD PMID:16514628 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estradiol results in increased expression of RUNX2 mRNA]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of RUNX2 mRNA]; fulvestrant inhibits the reaction [resveratrol results in increased expression of RUNX2 mRNA]
fulvestrant inhibits the reaction [naringin results in increased expression of RUNX2 mRNA]
CTD PMID:17689939 PMID:23596885 PMID:26362186 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S100a5 S100 calcium binding protein A5 multiple interactions
increases expression
ISO arsenite inhibits the reaction [Fulvestrant results in increased expression of S100A5 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of S100A5 mRNA] CTD PMID:31646340 NCBI chr 2:176,095,332...176,099,546
Ensembl chr 2:176,097,539...176,099,546
JBrowse link
G S100g S100 calcium binding protein G multiple interactions ISO
EXP
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of S100G mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of S100G protein]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of S100G mRNA]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of S100G protein]; Fulvestrant inhibits the reaction [octylphenol results in increased expression of S100G mRNA]; Fulvestrant inhibits the reaction [octylphenol results in increased expression of S100G protein]; Fulvestrant inhibits the reaction [Progesterone results in increased expression of S100G mRNA]
fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of S100G protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of S100G protein]; fulvestrant inhibits the reaction [butylparaben results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [butylparaben results in increased expression of S100G protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of S100G protein]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of S100G protein]; fulvestrant inhibits the reaction [isobutylparaben results in increased expression of S100G protein]; fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in increased expression of S100G protein]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [octylphenol results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [Triclosan results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [Triclosan results in increased expression of S100G protein]
CTD PMID:15509668 PMID:17361017 PMID:17504770 PMID:19654335 PMID:22062131 More... NCBI chr  X:31,705,853...31,708,422
Ensembl chr  X:31,705,866...31,708,433
JBrowse link
G Safb scaffold attachment factor B increases expression
multiple interactions
ISO Fulvestrant results in increased expression of SAFB mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of SAFB mRNA]; Cadmium inhibits the reaction [Fulvestrant results in increased expression of SAFB mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of SAFB mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of SAFB mRNA]
CTD PMID:31646340 NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in decreased expression of SCNN1G protein] CTD PMID:27522653 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO fulvestrant results in increased expression of SERPINB2 mRNA CTD PMID:16298037 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Serpinb9 serpin family B member 9 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of SERPINB9 mRNA]; fulvestrant inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA] CTD PMID:10681578 PMID:17237823 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of SERPINE1 protein] CTD PMID:31230753 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO fulvestrant results in decreased expression of SFPQ mRNA CTD PMID:16514628 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression
multiple interactions
ISO Fulvestrant results in decreased expression of SGK1 mRNA
Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of SGK1 protein]; Fulvestrant inhibits the reaction [chrysin results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Cyproterone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Megestrol Acetate results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Norethindrone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [oxybenzone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Spironolactone results in increased expression of SGK1 mRNA]
CTD PMID:26865669 PMID:29605410 PMID:33405908 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 decreases expression ISO fulvestrant results in decreased expression of SGK3 mRNA CTD PMID:26865669 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO fulvestrant results in decreased expression of SIAH2 mRNA CTD PMID:26865669 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Sin3b SIN3 transcription regulator family member B multiple interactions ISO Fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]; Fulvestrant promotes the reaction [SIN3B protein binds to PLK1 promoter]; Fulvestrant promotes the reaction [SIN3B protein binds to RNR2 promoter]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to PLK1 promoter]]; RB1 mutant form inhibits the reaction [Fulvestrant promotes the reaction [SIN3B protein binds to RNR2 promoter]] CTD PMID:21367843 NCBI chr16:17,123,277...17,160,070
Ensembl chr16:17,123,434...17,159,978
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [SIRT1 protein binds to IL6 promoter]] CTD PMID:24771768 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Six1 SIX homeobox 1 multiple interactions ISO fulvestrant inhibits the reaction [Genistein results in decreased expression of SIX1 mRNA] CTD PMID:21810550 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Skil SKI-like proto-oncogene multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of SKIL protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of SKIL protein]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of SKIL protein] CTD PMID:26407941 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions EXP fulvestrant inhibits the reaction [bisphenol A results in decreased expression of SLC16A1 protein] CTD PMID:27364615 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
increases expression
EXP fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of SLC1A2 protein]; fulvestrant inhibits the reaction [diarylpropionitrile results in increased expression of SLC1A2 protein]
fulvestrant results in increased expression of SLC1A2 protein
CTD PMID:24782323 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc25a5 solute carrier family 25 member 5 multiple interactions ISO fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of SLC25A5 mRNA] CTD PMID:16467188 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO fulvestrant results in decreased expression of SLC26A2 mRNA CTD PMID:16514628 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP fulvestrant inhibits the reaction [[resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose] CTD PMID:18426865 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc39a6 solute carrier family 39 member 6 decreases expression ISO fulvestrant results in decreased expression of SLC39A6 mRNA CTD PMID:16514628 NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO fulvestrant results in decreased expression of SLC7A5 mRNA CTD PMID:26865669 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions EXP Fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of SLCO1A2 protein] CTD PMID:27090119 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions ISO fulvestrant inhibits the reaction [Genistein results in increased expression of SLPI mRNA] CTD PMID:22553218 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO fulvestrant inhibits the reaction [4-nonylphenol results in decreased phosphorylation of SMAD3 protein]; fulvestrant inhibits the reaction [benzophenone results in decreased phosphorylation of SMAD3 protein]; fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of SMAD3 protein]; fulvestrant inhibits the reaction [Estradiol results in decreased phosphorylation of SMAD3 protein]; fulvestrant inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein] CTD PMID:24308608 PMID:26407941 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 decreases expression ISO fulvestrant results in decreased expression of SMARCA4 protein CTD PMID:24169358 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 increases expression ISO fulvestrant results in increased expression of SMARCB1 protein CTD PMID:24169358 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 increases expression ISO fulvestrant results in increased expression of SMARCC1 protein CTD PMID:24169358 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 decreases expression ISO fulvestrant results in decreased expression of SMARCC2 protein CTD PMID:24169358 NCBI chr 7:881,844...910,090
Ensembl chr 7:881,421...909,978
JBrowse link
G Smox spermine oxidase decreases expression ISO fulvestrant results in decreased expression of SMOX mRNA CTD PMID:26865669 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [2,4-dihydroxybenzophenone results in increased expression of SNAI1 protein]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of SNAI1 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of SNAI1 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of SNAI1 protein]; fulvestrant inhibits the reaction [fludioxonil results in increased expression of SNAI1 protein]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of SNAI1 protein]; fulvestrant inhibits the reaction [Triclosan results in increased expression of SNAI1 protein]
Fulvestrant results in increased expression of SNAI1 mRNA
CTD PMID:25690688 PMID:27145024 PMID:27480627 PMID:27539251 PMID:28284859 More... NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO fulvestrant inhibits the reaction [2,4-dihydroxybenzophenone results in increased expression of SNAI2 protein]; fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of SNAI2 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of SNAI2 mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of SNAI2 mRNA]; fulvestrant inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of SNAI2 mRNA]; fulvestrant inhibits the reaction [Triclosan results in increased expression of SNAI2 protein] CTD PMID:25690688 PMID:27145024 PMID:28844962 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO Fulvestrant inhibits the reaction [afimoxifene results in increased expression of SOCS1 mRNA] CTD PMID:16849584 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [Estradiol results in increased expression of SOCS3 mRNA]; Fulvestrant inhibits the reaction [Genistein results in increased expression of SOCS3 mRNA]
Fulvestrant results in decreased expression of SOCS3 mRNA
Fulvestrant results in decreased expression of SOCS3 protein
Fulvestrant inhibits the reaction [bisphenol F results in increased expression of SOCS3 mRNA]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of SOCS3 protein]
CTD PMID:16055089 PMID:31646340 PMID:32044397 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO fulvestrant results in increased expression of SOD1 mRNA CTD PMID:12154049 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP
ISO
Fulvestrant inhibits the reaction [Estradiol results in increased expression of SOD2 mRNA]; Fulvestrant inhibits the reaction [sannoshashinto affects the activity of SOD2 protein]
fulvestrant inhibits the reaction [Coumestrol results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [daidzein results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [Genistein results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [kaempferol results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [polydatin results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [resveratrol results in increased expression of SOD2 protein]
fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of SOD2 protein]]
CTD PMID:12816884 PMID:20962025 PMID:21215799 PMID:23526725 PMID:23615023 More... NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP fulvestrant inhibits the reaction [Estradiol results in increased expression of SOD3 mRNA] CTD PMID:12816884 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO fulvestrant results in decreased expression of SON mRNA CTD PMID:16514628 NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO fulvestrant promotes the reaction [SP1 protein binds to ESRRA promoter] CTD PMID:20211987 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sp3 Sp3 transcription factor multiple interactions ISO fulvestrant promotes the reaction [SP3 protein binds to ESRRA promoter] CTD PMID:20211987 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estradiol results in increased expression of SP7 mRNA]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of SP7 mRNA]; fulvestrant inhibits the reaction [resveratrol results in increased expression of SP7 mRNA]
fulvestrant inhibits the reaction [naringin results in increased expression of SP7 mRNA]
CTD PMID:17689939 PMID:23596885 PMID:26362186 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions ISO fulvestrant inhibits the reaction [notoginsenoside R1 results in increased expression of SPARC mRNA] CTD PMID:26362186 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression
EXP
ISO
fulvestrant inhibits the reaction [naringin results in increased secretion of SPP1 protein]
Fulvestrant results in increased expression of SPP1 mRNA
Cadmium inhibits the reaction [Fulvestrant results in increased expression of SPP1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of SPP1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of SPP1 mRNA]
CTD PMID:23596885 PMID:31646340 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of SRC protein]; Fulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of SRC protein] CTD PMID:22552774 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO fulvestrant results in decreased expression of SRSF1 mRNA CTD PMID:16514628 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Ssbp2 single-stranded DNA binding protein 2 increases expression ISO fulvestrant results in increased expression of SSBP2 mRNA CTD PMID:26865669 NCBI chr 2:22,650,488...22,933,696
Ensembl chr 2:22,651,258...22,933,696
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP
ISO
fulvestrant inhibits the reaction [Estradiol results in decreased expression of STAR mRNA]
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of STAR protein]
CTD PMID:23209616 PMID:30206973 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO fulvestrant results in decreased expression of STAT1 mRNA CTD PMID:16514628 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation
ISO Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of STAT3 mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; Fulvestrant inhibits the reaction [luteolin-7-O-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of STAT3 protein]]
Fulvestrant inhibits the reaction [bisphenol F results in increased phosphorylation of STAT3 protein]
Fulvestrant results in decreased phosphorylation of STAT3 protein
CTD PMID:28284859 PMID:29362861 PMID:31381935 PMID:32044397 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stk26 serine/threonine kinase 26 decreases expression ISO fulvestrant results in decreased expression of STK26 mRNA CTD PMID:16514628 NCBI chr  X:130,310,855...130,375,677
Ensembl chr  X:130,310,885...130,374,291
JBrowse link
G Stk39 serine threonine kinase 39 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of STK39 mRNA] CTD PMID:17131305 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO fulvestrant results in decreased expression of STMN1 mRNA CTD PMID:16514628 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 multiple interactions ISO fulvestrant inhibits the reaction [ESR1 protein binds to STUB1 protein] CTD PMID:16037132 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions EXP fulvestrant inhibits the reaction [Estradiol results in decreased expression of SULT1E1 mRNA] CTD PMID:23209616 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Svil supervillin decreases expression ISO fulvestrant results in decreased expression of SVIL mRNA CTD PMID:26865669 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Tacc1 transforming, acidic coiled-coil containing protein 1 increases expression ISO fulvestrant results in increased expression of TACC1 mRNA; fulvestrant results in increased expression of TACC1 protein CTD PMID:15072547 PMID:18984771 NCBI chr16:66,812,232...66,895,736
Ensembl chr16:66,812,295...66,895,733
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 decreases expression
increases expression
ISO fulvestrant results in decreased expression of TAF9 mRNA
fulvestrant results in increased expression of TAF9 mRNA
CTD PMID:12154049 PMID:16514628 NCBI chr 2:31,794,316...31,798,324 JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO Fulvestrant results in decreased expression of TARS1 mRNA CTD PMID:16514628 NCBI chr 2:60,368,251...60,387,733
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tcf19 transcription factor 19 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of TCF19 mRNA
fulvestrant results in decreased expression of TCF19 mRNA
CTD PMID:19016759 NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271
JBrowse link
G Tcim transcriptional and immune response regulator increases expression
multiple interactions
ISO Fulvestrant results in increased expression of TCIM mRNA
Fulvestrant inhibits the reaction [Estradiol results in decreased expression of TCIM mRNA]
CTD PMID:31646340 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
decreases expression
ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
fulvestrant results in decreased expression of TERT mRNA alternative form
CTD PMID:19501078 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO Fulvestrant inhibits the reaction [Estradiol results in increased expression of TFAM mRNA]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of TFAM mRNA] CTD PMID:22105178 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression ISO fulvestrant results in increased expression of TFAP2A mRNA CTD PMID:26865669 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tfap2c transcription factor AP-2 gamma decreases expression ISO fulvestrant results in decreased expression of TFAP2C mRNA CTD PMID:26865669 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Tff1 trefoil factor 1 decreases secretion
increases expression
multiple interactions
decreases expression
ISO fulvestrant results in decreased secretion of TFF1 protein
Fulvestrant results in increased expression of TFF1 mRNA
arsenite inhibits the reaction [Fulvestrant results in increased expression of TFF1 mRNA]; Estradiol inhibits the reaction [Fulvestrant results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [4-hydroxy-equilenin results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [[Arsenic Trioxide results in increased expression of ESR1 protein] which results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Arsenic Trioxide results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Coumestrol results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [desmethylicaritin results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Dexamethasone results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [EGF protein results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Equilin results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of TFF1 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased secretion of TFF1 protein]; Fulvestrant inhibits the reaction [Estriol results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Estrone results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Flame Retardants results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Genistein results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [hexabromocyclododecane results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [icariin results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [isobavachin results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Methoxychlor results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Progesterone results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [propylparaben results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Rosiglitazone results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Tartrazine results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Testosterone results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]
fulvestrant results in decreased expression of TFF1 mRNA
CTD PMID:9276643 PMID:12473173 PMID:14750165 PMID:15072547 PMID:15525692 More... NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tff2 trefoil factor 2 multiple interactions
decreases expression
ISO fulvestrant promotes the reaction [NCOR1 protein binds to TFF2 promoter]
fulvestrant results in decreased expression of TFF2 mRNA
CTD PMID:20696891 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619
JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO fulvestrant results in decreased expression of TFF3 mRNA CTD PMID:16202921 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
JBrowse link
G Tfpi tissue factor pathway inhibitor multiple interactions
increases expression
decreases secretion
ISO
EXP
[Fulvestrant co-treated with Raloxifene Hydrochloride] results in increased secretion of TFPI protein; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of and results in decreased secretion of TFPI protein]
fulvestrant results in increased expression of TFPI mRNA
fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased activity of TFPI protein]; fulvestrant inhibits the reaction [norethindrone acetate results in decreased activity of TFPI protein]
fulvestrant results in decreased secretion of TFPI protein
CTD PMID:15857755 PMID:17029634 PMID:26865669 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Tfrc transferrin receptor increases expression ISO fulvestrant results in increased expression of TFRC mRNA CTD PMID:12154049 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tg thyroglobulin increases expression EXP fulvestrant results in increased expression of TG mRNA CTD PMID:23238275 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [4-hydroxy-equilenin results in increased expression of TGFA mRNA]; Fulvestrant inhibits the reaction [arsenite results in decreased expression of TGFA mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of TGFA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of TGFA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of TGFA mRNA]
Fulvestrant results in increased expression of TGFA mRNA
CTD PMID:20540524 PMID:31646340 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO
EXP
[fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of FASLG mRNA; [fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of GZMB mRNA; [fulvestrant results in increased expression of TGFB1 protein] which results in increased expression of PRF1 mRNA; fulvestrant results in increased expression of TGFB1 protein
fulvestrant inhibits the reaction [bisphenol A results in increased expression of TGFB1 mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]
fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [CREBBP protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [NCOA1 protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to CYP11A1 gene]]; fulvestrant inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] promotes the reaction [PPARGC1A protein binds to HSD3B gene]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CREBBP protein]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to CYP11A1 gene]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to HSD3B gene]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to NCOA1 protein]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein promotes the reaction [ESR1 protein binds to PPARGC1A protein]]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased abundance of Progesterone]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased expression of CYP11A1 protein]]; fulvestrant inhibits the reaction [TGFB1 protein promotes the reaction [FSHB protein results in increased expression of HSD3B protein]]; TGFB1 protein promotes the reaction [fulvestrant results in increased expression of FOXP3 mRNA]
fulvestrant inhibits the reaction [Estradiol results in decreased activity of TGFB1 protein]
CTD PMID:18511507 PMID:20145137 PMID:20962747 PMID:25128825 PMID:27025157 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression ISO Fulvestrant results in decreased expression of TGFB3 mRNA CTD PMID:31646340 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 multiple interactions EXP fulvestrant inhibits the reaction [[Estradiol co-treated with FSHB protein] results in increased stability of and results in increased expression of TGFBR3 mRNA] CTD PMID:15878966 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Fulvestrant results in increased expression of THBS1 mRNA CTD PMID:31646340 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thbs2 thrombospondin 2 decreases expression ISO fulvestrant results in decreased expression of THBS2 mRNA CTD PMID:16514628 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Timeless timeless circadian regulator multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of TIMELESS mRNA
fulvestrant results in decreased expression of TIMELESS mRNA
CTD PMID:19016759 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO fulvestrant inhibits the reaction [bisphenol A results in increased expression of TIMP2 mRNA]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of TIMP2 protein]; fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TIMP2 mRNA]; fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TIMP2 protein]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of TIMP2 mRNA]; fulvestrant inhibits the reaction [Estradiol results in decreased expression of TIMP2 protein] CTD PMID:19956873 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tlr9 toll-like receptor 9 decreases expression ISO fulvestrant results in decreased expression of TLR9 mRNA CTD PMID:28811679 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [arsenite results in decreased expression of TM4SF1 mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of TM4SF1 mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of TM4SF1 mRNA]
Fulvestrant results in increased expression of TM4SF1 mRNA
CTD PMID:31646340 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
JBrowse link
G Tmpo thymopoietin decreases expression ISO fulvestrant results in decreased expression of TMPO mRNA CTD PMID:16514628 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
[Fulvestrant results in decreased susceptibility to CpG ODN 1826] which results in decreased expression of TNF protein; Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]]; Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of TNF protein]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of TNF mRNA]]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of TNF mRNA]]; Fulvestrant inhibits the reaction [Estradiol results in decreased activity of TNF protein]; Fulvestrant inhibits the reaction [Estrogens inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Fulvestrant inhibits the reaction [Estrogens inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [CREBBP protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOA2 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOA3 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NCOR2 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [NMNAT1 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [RCOR1 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [RELA protein modified form binds to IL6 promoter]]; Fulvestrant inhibits the reaction [[TNF protein co-treated with Resveratrol] promotes the reaction [SIRT1 protein binds to IL6 promoter]]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of and results in increased secretion of TNF protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of TNF]; Fulvestrant inhibits the reaction [Estriol inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; Fulvestrant inhibits the reaction [Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of and results in increased secretion of TNF protein]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of TNF]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of PTGER4 mRNA]]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of TNFRSF11B mRNA]]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]
Fulvestrant inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]; Fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Fulvestrant inhibits the reaction [Resveratrol results in decreased expression of TNF protein]
CTD PMID:12547825 PMID:12860292 PMID:17850464 PMID:20056579 PMID:20962747 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Estradiol results in decreased expression of TNFRSF11B mRNA]; Fulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of TNFRSF11B mRNA]]
Fulvestrant results in increased expression of TNFRSF11B mRNA
Fulvestrant inhibits the reaction [dioscin results in increased expression of TNFRSF11B mRNA]; Fulvestrant inhibits the reaction [naringenin-6-C-glucoside results in increased expression of TNFRSF11B mRNA]
CTD PMID:21864313 PMID:24742230 PMID:24771768 PMID:31646340 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Fulvestrant inhibits the reaction [dioscin results in increased expression of TNFSF11 mRNA]; Fulvestrant inhibits the reaction [naringenin-6-C-glucoside results in decreased expression of TNFSF11 mRNA] CTD PMID:21864313 PMID:24742230 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnpo1 transportin 1 decreases expression ISO fulvestrant results in decreased expression of TNPO1 mRNA CTD PMID:16514628 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Top1 DNA topoisomerase I decreases expression ISO fulvestrant results in decreased expression of TOP1 mRNA CTD PMID:16514628 NCBI chr 3:149,293,658...149,375,405
Ensembl chr 3:149,293,403...149,376,623
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression ISO fulvestrant results in increased expression of TOP2A mRNA CTD PMID:12154049 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Top2b DNA topoisomerase II beta decreases expression ISO fulvestrant results in decreased expression of TOP2B mRNA CTD PMID:16514628 NCBI chr15:9,051,661...9,111,220
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of TP53 protein]; Fulvestrant inhibits the reaction [Estradiol affects the localization of TP53 protein]
fulvestrant results in decreased expression of TP53 protein
CTD PMID:15870704 PMID:24169358 PMID:29383186 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trak2 trafficking kinesin protein 2 decreases expression ISO fulvestrant results in decreased expression of TRAK2 mRNA CTD PMID:16514628 NCBI chr 9:60,348,531...60,414,036
Ensembl chr 9:60,350,012...60,413,996
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP fulvestrant inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:18617618 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO Fulvestrant promotes the reaction [bisphenol A results in increased expression of TRPV5 mRNA]; Fulvestrant promotes the reaction [Estradiol results in increased expression of TRPV5 protein] CTD PMID:30061528 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions
increases expression
ISO [Fulvestrant co-treated with bisphenol A] results in increased expression of TRPV6 mRNA; Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of TRPV6 mRNA]
Fulvestrant results in increased expression of TRPV6 protein
CTD PMID:30061528 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; fulvestrant inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]; fulvestrant promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA] CTD PMID:23183181 PMID:25136773 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ttk Ttk protein kinase multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of TTK mRNA
fulvestrant results in decreased expression of TTK mRNA
CTD PMID:19016759 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Tuba1b tubulin, alpha 1B increases expression ISO fulvestrant results in increased expression of TUBA1B mRNA CTD PMID:12154049 NCBI chr 7:130,090,669...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO fulvestrant inhibits the reaction [Estradiol results in increased expression of TUBB3 mRNA] CTD PMID:19466750 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression ISO fulvestrant results in decreased expression of TXNRD1 mRNA CTD PMID:16514628 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO fulvestrant results in increased expression of UGT1A1 mRNA CTD PMID:15072547 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ung uracil-DNA glycosylase decreases expression ISO fulvestrant results in decreased expression of UNG mRNA CTD PMID:16514628 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
JBrowse link
G Usp32 ubiquitin specific peptidase 32 decreases expression ISO fulvestrant results in decreased expression of USP32 mRNA CTD PMID:16514628 NCBI chr10:69,855,885...70,029,075
Ensembl chr10:69,855,885...70,029,137
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G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO
EXP
fulvestrant inhibits the reaction [Estriol inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; fulvestrant inhibits the reaction [Genistein inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]
fulvestrant inhibits the reaction [biochanin A results in decreased expression of VCAM1 protein]; fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of VCAM1 protein]
CTD PMID:12547825 PMID:16223672 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G Vdr vitamin D receptor multiple interactions
decreases expression
ISO Cadmium inhibits the reaction [Fulvestrant results in decreased expression of VDR mRNA]; Fulvestrant inhibits the reaction [Cadmium results in decreased expression of VDR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of VDR protein]; Fulvestrant inhibits the reaction [Genistein results in increased expression of VDR protein]; Fulvestrant inhibits the reaction [glycitein results in increased expression of VDR protein]
Fulvestrant results in decreased expression of VDR mRNA; Fulvestrant results in decreased expression of VDR protein
CTD PMID:15930183 PMID:17088408 PMID:31646340 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
ISO Fulvestrant affects the reaction [Chlorpyrifos results in increased expression of VEGFA protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [arsenite results in increased expression of VEGFA mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of VEGFA mRNA]; Fulvestrant inhibits the reaction [Dieldrin results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of VEGFA mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [Genistein results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [Hexachlorobenzene results in increased expression of VEGFA protein]
Fulvestrant results in decreased expression of VEGFA mRNA
CTD PMID:18252963 PMID:31646340 PMID:32526215 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G Vim vimentin multiple interactions