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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluocinolone acetonide
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Accession:CHEBI:31623 term browser browse the term
Definition:A fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatment of various skin disorders.
Synonyms:exact_synonym: (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
 related_synonym: 6alpha,9alpha-difluoro-16alpha-hydroxyprednisolone 16,17-acetonide;   6alpha-fluorotriamcinolone acetonide;   Coriphate;   Cortiplastol;   Derma-Smoothe/FS;   Dermalar;   Flucinar;   Flucort;   Fluocet;   Fluonid;   Fluotrex;   Fluovitif;   Flupollon;   Fluzon;   Formula=C24H30F2O6;   Iluvien;   InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1;   InChIKey=FEBLZLNTKCEFIT-VSXGLTOVSA-N;   Jellin;   Localyn;   Omniderm;   Percutina;   Prodermin;   Radiocin;   Retisert;   SMILES=CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO;   Sinalar;   Synalar;   Synamol;   Synandone;   Synandrone;   Synemol;   Synotic;   Synsac;   Tefunote;   acetonide de fluocinolone;   acetonido de fluocinolona;   fluocinolone 16,17-acetonide;   fluocinoloni acetonidum
 xref: CAS:67-73-2;   DrugBank:DB00591;   Drug_Central:1204;   HMDB:HMDB0014729;   KEGG:D01825
 xref_mesh: MESH:D005446
 xref: PMID:21238799;   PMID:21277557;   PMID:21459216;   PMID:23321234;   PMID:23323586;   Patent:US3014938;   Patent:US3126375;   Reaxys:1358396;   Wikipedia:Fluocinolone_acetonide

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fluocinolone acetonide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha multiple interactions ISO Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] CTD PMID:8435107 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:3677084 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19908
    role 19883
      application 19717
        anti-inflammatory agent 16527
          anti-inflammatory drug 14957
            fluocinolone acetonide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19908
    subatomic particle 19906
      composite particle 19906
        hadron 19906
          baryon 19906
            nucleon 19906
              atomic nucleus 19906
                atom 19906
                  main group element atom 19853
                    p-block element atom 19853
                      carbon group element atom 19799
                        carbon atom 19794
                          organic molecular entity 19794
                            organic group 18960
                              organic divalent group 18941
                                organodiyl group 18941
                                  carbonyl group 18893
                                    carbonyl compound 18893
                                      ketone 17190
                                        oxyketone 8827
                                          alpha-oxyketone 8827
                                            alpha-hydroxy ketone 8827
                                              primary alpha-hydroxy ketone 7708
                                                fluocinolone acetonide 2
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