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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Falecalcitriol
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Accession:CHEBI:31590 term browser browse the term
Synonyms:related_synonym: (+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol;   Falecalcitoriol;   Formula=C27H38F6O3;   Hornel (TN);   InChI=1S/C27H38F6O3/c1-16(6-4-13-25(36,26(28,29)30)27(31,32)33)21-10-11-22-18(7-5-12-24(21,22)3)8-9-19-14-20(34)15-23(35)17(19)2/h8-9,16,20-23,34-36H,2,4-7,10-15H2,1,3H3/b18-8+,19-9+/t16-,20-,21-,22+,23+,24-/m1/s1;   InChIKey=XPYGGHVSFMUHLH-WSRTYSJNSA-N;   SMILES=C\\1(/C[C@H](C[C@@H](C1=C)O)O)=C/C=C/2\\CCC[C@]3([C@]2(CC[C@@]3([C@](C)(CCCC(C(F)(F)F)(O)C(F)(F)F)[H])[H])[H])C;   flocacitriol;   flocalcitriol;   flocalcitrol
 xref: CAS:83805-11-2;   Drug_Central:1127;   KEGG:D01662
 xref_mesh: MESH:C040488


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Falecalcitriol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of ALPL mRNA CTD PMID:12016462 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of BGLAP mRNA CTD PMID:12016462 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein] CTD PMID:16059639 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein] CTD PMID:16059639 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of SPP1 mRNA CTD PMID:12016462 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Vdr vitamin D receptor multiple interactions
increases activity		 ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein]; 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein]
26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog results in increased activity of VDR protein mutant form		 CTD PMID:16059639 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          carbon atom 19698
            organic molecular entity 19698
              Falecalcitriol 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            Falecalcitriol 6
paths to the root