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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Falecalcitriol
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Accession:CHEBI:31590 term browser browse the term
Synonyms:related_synonym: (+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol;   Falecalcitoriol;   Formula=C27H38F6O3;   Hornel (TN);   InChI=1S/C27H38F6O3/c1-16(6-4-13-25(36,26(28,29)30)27(31,32)33)21-10-11-22-18(7-5-12-24(21,22)3)8-9-19-14-20(34)15-23(35)17(19)2/h8-9,16,20-23,34-36H,2,4-7,10-15H2,1,3H3/b18-8+,19-9+/t16-,20-,21-,22+,23+,24-/m1/s1;   InChIKey=XPYGGHVSFMUHLH-WSRTYSJNSA-N;   SMILES=C\\1(/C[C@H](C[C@@H](C1=C)O)O)=C/C=C/2\\CCC[C@]3([C@]2(CC[C@@]3([C@](C)(CCCC(C(F)(F)F)(O)C(F)(F)F)[H])[H])[H])C;   flocacitriol;   flocalcitriol;   flocalcitrol
 xref: CAS:83805-11-2;   Drug_Central:1127;   KEGG:D01662
 xref_mesh: MESH:C040488



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Falecalcitriol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of ALPL mRNA CTD PMID:12016462 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of BGLAP mRNA CTD PMID:12016462 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein] CTD PMID:16059639 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein] CTD PMID:16059639 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of SPP1 mRNA CTD PMID:12016462 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Vdr vitamin D receptor multiple interactions
increases activity
ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein]; 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein]
26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog results in increased activity of VDR protein mutant form
CTD PMID:16059639 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          carbon atom 19609
            organic molecular entity 19609
              Falecalcitriol 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            Falecalcitriol 6
paths to the root