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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Falecalcitriol
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Accession:CHEBI:31590 term browser browse the term
Synonyms:related_synonym: (+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol;   Falecalcitoriol;   Formula=C27H38F6O3;   Hornel (TN);   InChI=1S/C27H38F6O3/c1-16(6-4-13-25(36,26(28,29)30)27(31,32)33)21-10-11-22-18(7-5-12-24(21,22)3)8-9-19-14-20(34)15-23(35)17(19)2/h8-9,16,20-23,34-36H,2,4-7,10-15H2,1,3H3/b18-8+,19-9+/t16-,20-,21-,22+,23+,24-/m1/s1;   InChIKey=XPYGGHVSFMUHLH-WSRTYSJNSA-N;   SMILES=C\\1(/C[C@H](C[C@@H](C1=C)O)O)=C/C=C/2\\CCC[C@]3([C@]2(CC[C@@]3([C@](C)(CCCC(C(F)(F)F)(O)C(F)(F)F)[H])[H])[H])C;   flocacitriol;   flocalcitriol;   flocalcitrol
 xref: CAS:83805-11-2;   Drug_Central:1127;   KEGG:D01662
 xref_mesh: MESH:C040488


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Falecalcitriol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of ALPL mRNA CTD PMID:12016462 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of BGLAP mRNA CTD PMID:12016462 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein] CTD PMID:16059639 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein] CTD PMID:16059639 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 results in increased expression of SPP1 mRNA CTD PMID:12016462 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Vdr vitamin D receptor multiple interactions
increases activity
ISO 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to MED1 protein]; 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog promotes the reaction [VDR protein mutant form binds to NCOA2 protein]
26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 analog results in increased activity of VDR protein mutant form
CTD PMID:16059639 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Falecalcitriol 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Falecalcitriol 6
paths to the root

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