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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethylestrenol
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Accession:CHEBI:31578 term browser browse the term
Definition:A 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used to promote growth in boys with delayed bone growth.
Synonyms:exact_synonym: (17alpha)-19-norpregn-4-en-17-ol
 related_synonym: 17alpha-ethyl-17beta-hydroxy-4-estrene;   17alpha-ethylestr-4-en-17beta-ol;   17beta-hydroxy-17alpha-ethyl-19-nor-4-androstene;   19-nor-17alpha-pregn-4-en-17beta-ol;   Durabolin-O;   Duraboral;   Formula=C20H32O;   InChI=1S/C20H32O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h6,15-18,21H,3-5,7-13H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1;   InChIKey=AOXRBFRFYPMWLR-XGXHKTLJSA-N;   Maxibalin;   Maxibolin;   Neodurabolin;   Orabolin;   Orgabolin;   Orgaboral;   SMILES=CC[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCC[C@@H]4[C@H]3CC[C@]12C;   ethylestrenolum;   ethylnandrol;   etilestrenol
 xref: CAS:965-90-2;   DrugBank:DB01493;   Drug_Central:1094;   KEGG:D01414
 xref_mesh: MESH:D005032
 xref: PMID:10406207;   PMID:14001307;   PMID:14482850;   PMID:3865482;   PMID:637620;   PMID:7193965;   PMID:7233967;   PMID:7233968;   Patent:US2878267;   Reaxys:3140841;   Wikipedia:Ethylestrenol



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ethylestrenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Ethylestrenol inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        molecular messenger 18682
          hormone 18528
            anabolic agent 495
              ethylestrenol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic polycyclic compound 17279
                                  steroid 14707
                                    hydroxy steroid 14451
                                      17-hydroxy steroid 14094
                                        17beta-hydroxy steroid 13342
                                          ethylestrenol 1
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