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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethylestrenol
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Accession:CHEBI:31578 term browser browse the term
Definition:A 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used to promote growth in boys with delayed bone growth.
Synonyms:exact_synonym: (17alpha)-19-norpregn-4-en-17-ol
 related_synonym: 17alpha-ethyl-17beta-hydroxy-4-estrene;   17alpha-ethylestr-4-en-17beta-ol;   17beta-hydroxy-17alpha-ethyl-19-nor-4-androstene;   19-nor-17alpha-pregn-4-en-17beta-ol;   Durabolin-O;   Duraboral;   Formula=C20H32O;   InChI=1S/C20H32O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h6,15-18,21H,3-5,7-13H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1;   InChIKey=AOXRBFRFYPMWLR-XGXHKTLJSA-N;   Maxibalin;   Maxibolin;   Neodurabolin;   Orabolin;   Orgabolin;   Orgaboral;   SMILES=CC[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCC[C@@H]4[C@H]3CC[C@]12C;   ethylestrenolum;   ethylnandrol;   etilestrenol
 xref: CAS:965-90-2;   DrugBank:DB01493;   Drug_Central:1094;   KEGG:D01414
 xref_mesh: MESH:D005032
 xref: PMID:10406207;   PMID:14001307;   PMID:14482850;   PMID:3865482;   PMID:637620;   PMID:7193965;   PMID:7233967;   PMID:7233968;   Patent:US2878267;   Reaxys:3140841;   Wikipedia:Ethylestrenol


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ethylestrenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Ethylestrenol inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        molecular messenger 18249
          hormone 17998
            anabolic agent 481
              ethylestrenol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic polycyclic compound 16384
                                  steroid 12788
                                    hydroxy steroid 12371
                                      17-hydroxy steroid 11855
                                        17beta-hydroxy steroid 10575
                                          ethylestrenol 1
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