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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethylestrenol
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Accession:CHEBI:31578 term browser browse the term
Definition:A 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used to promote growth in boys with delayed bone growth.
Synonyms:exact_synonym: (17alpha)-19-norpregn-4-en-17-ol
 related_synonym: 17alpha-ethyl-17beta-hydroxy-4-estrene;   17alpha-ethylestr-4-en-17beta-ol;   17beta-hydroxy-17alpha-ethyl-19-nor-4-androstene;   19-nor-17alpha-pregn-4-en-17beta-ol;   Durabolin-O;   Duraboral;   Formula=C20H32O;   InChI=1S/C20H32O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h6,15-18,21H,3-5,7-13H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1;   InChIKey=AOXRBFRFYPMWLR-XGXHKTLJSA-N;   Maxibalin;   Maxibolin;   Neodurabolin;   Orabolin;   Orgabolin;   Orgaboral;   SMILES=CC[C@]1(O)CC[C@H]2[C@@H]3CCC4=CCCC[C@@H]4[C@H]3CC[C@]12C;   ethylestrenolum;   ethylnandrol;   etilestrenol
 xref: CAS:965-90-2;   DrugBank:DB01493;   Drug_Central:1094;   KEGG:D01414
 xref_mesh: MESH:D005032
 xref: PMID:10406207;   PMID:14001307;   PMID:14482850;   PMID:3865482;   PMID:637620;   PMID:7193965;   PMID:7233967;   PMID:7233968;   Patent:US2878267;   Reaxys:3140841;   Wikipedia:Ethylestrenol



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ethylestrenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Ethylestrenol inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      biological role 19746
        molecular messenger 18298
          hormone 18081
            anabolic agent 484
              ethylestrenol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic molecule 19545
                              organic cyclic compound 19339
                                organic polycyclic compound 16569
                                  steroid 13347
                                    hydroxy steroid 12976
                                      17-hydroxy steroid 12534
                                        17beta-hydroxy steroid 11399
                                          ethylestrenol 1
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