CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Ethyl icosapentate
Accession: CHEBI:31570
browse the term
Synonyms: related_synonym: Formula=C22H34O2
xref: CAS:73310-10-8; KEGG:D01892
xref_mesh: MESH:C035276
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Bax
BCL2 associated X, apoptosis regulator
decreases expression
ISO
eicosapentaenoic acid ethyl ester results in decreased expression of BAX mRNA
CTD
PMID:20868657
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Casp3
caspase 3
decreases expression
ISO
eicosapentaenoic acid ethyl ester results in decreased expression of CASP3 mRNA
CTD
PMID:20868657
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of CCL2 mRNA
CTD
PMID:23665937
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl5
C-C motif chemokine ligand 5
multiple interactions
ISO
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of CCL5 mRNA
CTD
PMID:23665937
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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F10
coagulation factor X
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F10 protein
CTD
PMID:14614217
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
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F11
coagulation factor XI
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F11 protein
CTD
PMID:14614217
NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
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F12
coagulation factor XII
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F12 protein
CTD
PMID:14614217
NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
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F2
coagulation factor II, thrombin
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F2 protein
CTD
PMID:14614217
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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F5
coagulation factor V
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F5 protein
CTD
PMID:14614217
NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
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F7
coagulation factor VII
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F7 protein
CTD
PMID:14614217
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
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F8
coagulation factor VIII
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F8 protein
CTD
PMID:14614217
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
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F9
coagulation factor IX
decreases activity
EXP
eicosapentaenoic acid ethyl ester results in decreased activity of F9 protein
CTD
PMID:14614217
NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835
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Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of ICAM1 mRNA
CTD
PMID:23665937
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Il1b
interleukin 1 beta
multiple interactions
ISO
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of IL1B mRNA
CTD
PMID:23665937
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Lep
leptin
multiple interactions increases expression increases secretion
ISO
Diazooxonorleucine inhibits the reaction [eicosapentaenoic acid ethyl ester results in increased expression of LEP mRNA]; Diazooxonorleucine inhibits the reaction [eicosapentaenoic acid ethyl ester results in increased secretion of LEP protein]
CTD
PMID:10753628
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Plat
plasminogen activator, tissue type
increases expression
EXP
eicosapentaenoic acid ethyl ester results in increased expression of PLAT protein
CTD
PMID:14614217
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plg
plasminogen
increases expression
EXP
eicosapentaenoic acid ethyl ester results in increased expression of PLG protein
CTD
PMID:14614217
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
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Scd
stearoyl-CoA desaturase
multiple interactions
ISO
eicosapentaenoic acid ethyl ester inhibits the reaction [[Sodium Cholate co-treated with Dietary Fats] results in increased expression of SCD1 mRNA]
CTD
PMID:23665937
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Serpine1
serpin family E member 1
decreases expression
EXP
eicosapentaenoic acid ethyl ester results in decreased expression of SERPINE1 protein
CTD
PMID:14614217
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpinf2
serpin family F member 2
decreases expression
EXP
eicosapentaenoic acid ethyl ester results in decreased expression of SERPINF2 protein
CTD
PMID:14614217
NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
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Soat2
sterol O-acyltransferase 2
multiple interactions
ISO
eicosapentaenoic acid ethyl ester inhibits the reaction [[Sodium Cholate co-treated with Dietary Fats] results in increased expression of SOAT2 mRNA]
CTD
PMID:23665937
NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
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