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ONTOLOGY REPORT - ANNOTATIONS


Term:emtricitabine
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Accession:CHEBI:31536 term browser browse the term
Definition:An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection.
Synonyms:related_synonym: (-)-2'-deoxy-5-fluoro-3'-thiacytidine;   (-)-FTC;   (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine;   (-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one;   (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone;   4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one;   5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine;   Formula=C8H10FN3O3S;   InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1;   InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N;   SMILES=Nc1nc(=O)n(cc1F)[C@@H]1CS[C@H](CO)O1
 alt_id: CHEBI:174911
 xref: Beilstein:5908714 "Beilstein";   CAS:143491-57-0 "ChemIDplus";   CAS:143491-57-0 "KEGG COMPOUND";   DrugBank:DB00879;   Drug_Central:1003 "DrugCentral";   KEGG:C12599;   KEGG:D01199
 xref_mesh: MESH:D000068679
 xref: PDBeChem:ETV;   PMID:11491420 "Europe PMC";   PMID:14609348 "Europe PMC";   PMID:14693538 "Europe PMC";   PMID:15206508 "Europe PMC";   PMID:15249567 "Europe PMC";   PMID:15588339 "Europe PMC";   PMID:15875341 "Europe PMC";   PMID:15977972 "Europe PMC";   PMID:16034488 "Europe PMC";   PMID:16323102 "Europe PMC";   PMID:16401810 "Europe PMC";   PMID:17526857 "Europe PMC";   PMID:19493710 "Europe PMC";   PMID:22915463 "Europe PMC";   PMID:22917277 "Europe PMC";   PMID:22935078 "Europe PMC";   PMID:23337366 "Europe PMC";   PMID:23361642 "Europe PMC";   PMID:25017682 "Europe PMC";   Patent:US5538975;   Patent:WO9214743;   Wikipedia:Emtricitabine


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emtricitabine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Dck deoxycytidine kinase JBrowse link 14 20,935,442 20,952,939 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19614
    role 19557
      biological role 19550
        antimicrobial agent 17062
          antiviral agent 3597
            antiviral drug 1640
              emtricitabine 2
                Descovy 0
                Genvoya 0
                Odefsey 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19614
    subatomic particle 19610
      composite particle 19610
        hadron 19610
          baryon 19610
            nucleon 19610
              atomic nucleus 19610
                atom 19610
                  main group element atom 19489
                    p-block element atom 19489
                      carbon group element atom 19362
                        carbon atom 19354
                          organic molecular entity 19354
                            heteroorganic entity 18925
                              organochalcogen compound 18674
                                organooxygen compound 18582
                                  carbohydrates and carbohydrate derivatives 11697
                                    carbohydrate 11697
                                      carbohydrate derivative 11309
                                        glycosyl compound 10289
                                          N-glycosyl compound 4202
                                            nucleoside analogue 699
                                              emtricitabine 2
                                                Descovy 0
                                                Genvoya 0
                                                Odefsey 0
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