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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:droxidopa
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Accession:CHEBI:31524 term browser browse the term
Definition:A serine derivative that is L-serine substituted at the beta-position by a 3,4-dihydroxyphenyl group. A prodrug for noradrenalone, it is used for treatment of neurogenic orthostatic hypotension
Synonyms:exact_synonym: (betaR)-beta,3-dihydroxy-L-tyrosine
 related_synonym: (-)-(2S,3R)-2-amino-3-hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid;   (2S,3R)-3,4-dihydroxy-phenylserine;   Dops;   Droxydopa;   Formula=C9H11NO5;   InChI=1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1;   InChIKey=QXWYKJLNLSIPIN-JGVFFNPUSA-N;   L-DOPS;   L-Dihydroxyphenylserine;   L-Threodops;   L-threo-dihydroxyphenylserine;   Northera;   SM 5688;   SMILES=N[C@@H]([C@H](O)c1ccc(O)c(O)c1)C(O)=O;   droxidopum;   threo-Dopaserine
 xref: CAS:23651-95-8;   DrugBank:DB06262;   Drug_Central:971;   HMDB:HMDB0015627;   KEGG:D01277;   PMID:11710796;   PMID:20063034;   PMID:20207766;   PMID:20220040;   PMID:21705113;   PMID:22561478;   PMID:22610782;   PMID:23224983;   PMID:24224390;   PMID:24326693;   PMID:24517276;   PMID:24644107;   PMID:24729712;   PMID:24883005;   PMID:24944260;   PMID:24958960;   Patent:JP2005247828;   Patent:NZ579368;   Patent:US2008221170;   Patent:US2012010293;   Patent:US2013253061;   Reaxys:7112431;   Wikipedia:Droxidopa



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      application 19675
        pro-agent 11550
          prodrug 11310
            droxidopa 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    main group molecular entity 19804
                      s-block molecular entity 19637
                        hydrogen molecular entity 19618
                          hydrides 19124
                            organic hydride 18697
                              organic fundamental parent 18697
                                hydrocarbon 18440
                                  cyclic hydrocarbon 17234
                                    monocyclic hydrocarbon 6148
                                      annulene 5799
                                        aromatic annulene 5799
                                          benzene 5799
                                            alkylbenzene 3516
                                              methylbenzene 3370
                                                toluene 3242
                                                  benzyl group 2651
                                                    phenylalanine 2651
                                                      phenylalanine derivative 2617
                                                        tyrosine derivative 461
                                                          L-tyrosine derivative 6
                                                            droxidopa 0
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