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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyclothiazide
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Accession:CHEBI:31448 term browser browse the term
Definition:3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
Synonyms:exact_synonym: 3-(bicyclo[2.2.1]hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
 related_synonym: 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide;   6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;   6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide;   Formula=C14H16ClN3O4S2;   InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20);   InChIKey=BOCUKUHCLICSIY-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C2CC3CC2C=C3)cc1Cl;   ciclotiazida;   cyclothiazidum
 alt_id: CHEBI:47361;   CHEBI:598653
 xref: Beilstein:722843;   CAS:2259-96-3;   DrugBank:DB00606;   Drug_Central:761;   KEGG:C12685;   KEGG:D01256;   LINCS:LSM-4421
 xref_mesh: MESH:C004639
 xref: PDBeChem:CYZ;   PMID:19338354;   Patent:US3275625;   Wikipedia:Cyclothiazide


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Term Annotations click to browse term
  CHEBI ontology 879
    role 859
      application 496
        pharmaceutical 435
          drug 435
            diuretic 7
              cyclothiazide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 879
    subatomic particle 864
      composite particle 864
        hadron 864
          baryon 864
            nucleon 864
              atomic nucleus 864
                atom 864
                  main group element atom 854
                    p-block element atom 851
                      carbon group element atom 827
                        carbon atom 826
                          organic molecular entity 826
                            organic molecule 738
                              organic cyclic compound 647
                                organic heterocyclic compound 362
                                  organonitrogen heterocyclic compound 221
                                    thiazide 0
                                      benzothiadiazine 0
                                        cyclothiazide 0
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