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ONTOLOGY REPORT - ANNOTATIONS


Term:crotamiton
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Accession:CHEBI:31439 term browser browse the term
Definition:An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.
Synonyms:exact_synonym: N-ethyl-N-(2-methylphenyl)but-2-enamide
 related_synonym: Formula=C13H17NO;   InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3;   InChIKey=DNTGGZPQPQTDQF-UHFFFAOYSA-N;   N-ethyl-o-crotonotoluidide;   SMILES=CCN(C(=O)C=CC)c1ccccc1C;   crotalgin;   crotamitone;   crotamitonum;   crotonyl-N-ethyl-o-toluidine
 xref: Beilstein:3275497 "Beilstein";   CAS:483-63-6 "ChemIDplus";   CAS:483-63-6 "KEGG DRUG";   CAS:483-63-6 "NIST Chemistry WebBook";   DrugBank:DB00265;   Drug_Central:744 "DrugCentral";   KEGG:D01381;   LINCS:LSM-3274
 xref_mesh: MESH:C005553
 xref: Patent:GB615137


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crotamiton term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pesticide 15800
          acaricide 8864
            scabicide 453
              crotamiton 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                alpha,beta-unsaturated carboxylic acid amide 4750
                                                  enamide 4750
                                                    crotamiton 1
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