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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cloxazolam
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Accession:CHEBI:31426 term browser browse the term
Definition:An oxazolobenzodiazepine that has formula C17H14Cl2N2O2.
Synonyms:related_synonym: Formula=C17H14Cl2N2O2;   InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22);   InChIKey=ZIXNZOBDFKSQTC-UHFFFAOYSA-N;   SMILES=Clc1ccc2NC(=O)CN3CCOC3(c3ccccc3Cl)c2c1;   cloxazolazepam
 xref: CAS:24166-13-0;   Drug_Central:721;   KEGG:D01268
 xref_mesh: MESH:C005522


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cloxazolam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c18 aldo-keto reductase family 1, member C18 decreases activity ISO cloxazolam results in decreased activity of AKR1C3 protein CTD PMID:11995921 PMID:12604236 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653 		JBrowse link
G Akr1c20 aldo-keto reductase family 1, member C20 decreases activity ISO cloxazolam results in decreased activity of AKR1C1 protein CTD PMID:12604236 NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344 		JBrowse link
G Akr1c21 aldo-keto reductase family 1, member C21 decreases activity ISO cloxazolam results in decreased activity of AKR1C2 protein CTD PMID:12604236 NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540 		JBrowse link
G Akr1c6 aldo-keto reductase family 1, member C6 decreases activity ISO cloxazolam results in decreased activity of AKR1C4 protein CTD PMID:12604236 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        NMR chemical shift reference compound 18719
          ammonia 18425
            organic amino compound 18425
              hemiaminal ether 665
                cloxazolam 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  azane 18426
                                    ammonia 18425
                                      organic amino compound 18425
                                        hemiaminal 736
                                          hemiaminal ether 665
                                            cloxazolam 4
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