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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bleomycin A2
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Accession:CHEBI:3139 term browser browse the term
Definition:A bleomycin that has formula C55H84N17O21S3.
Synonyms:exact_synonym: (betaR)-N(alpha)-{[6-amino-2-((1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl)-5-methylpyrimidin-4-yl]carbonyl}-beta-{2-O-[3-O-(aminocarbonyl)-alpha-D-mannopyranosyl]-alpha-L-gulopyranosyloxy}-N-[(1R,2S,3S)-5-({(1S,2R)-1-[({2-[4-({[3-(dimethylsulfonio)propyl]amino}carbonyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)carbonyl]-2-hydroxypropyl}amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl]-L-histidinamide
 related_synonym: Bleomycin;   Formula=C55H84N17O21S3;   InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-/m0/s1;   InChIKey=OYVAGSVQBOHSSS-UAPAGMARSA-O;   N(1)-[3-(dimethylsulfonio)propyl]bleomycinamide;   SMILES=[H][C@](C)(NC(=O)[C@@]([H])(NC(=O)c1nc(nc(N)c1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@]([H])(O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1c[nH]cn1)[C@@H](O)[C@H](C)C(=O)N[C@]([H])(C(=O)NCCc1nc(cs1)-c1nc(cs1)C(=O)NCCC[S+](C)C)[C@@]([H])(C)O
 alt_id: CHEBI:165316;   CHEBI:357107;   CHEBI:41102;   CHEBI:653800
 xref: Beilstein:4379083;   CAS:11056-06-7;   CAS:11116-31-7;   Gmelin:1667354;   KEGG:C06854;   KEGG:C15773;   KEGG:D07535;   KNApSAcK:C00018738
 xref_mesh: MESH:D001761
 xref: PDBeChem:BLM;   PMID:12477361;   Wikipedia:Bleomycin


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bleomycin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4921524L21Rik RIKEN cDNA 4921524L21 gene decreases expression ISO Bleomycin results in decreased expression of CCDC144NL mRNA CTD PMID:33770205 NCBI chr18:6,603,629...6,638,970
Ensembl chr18:6,603,629...6,638,970 		JBrowse link
G Abca3 ATP-binding cassette, sub-family A member 3 decreases expression ISO Bleomycin results in decreased expression of ABCA3 mRNA; Bleomycin results in decreased expression of ABCA3 protein CTD PMID:34425168 NCBI chr17:24,570,997...24,629,178
Ensembl chr17:24,570,924...24,629,175 		JBrowse link
G Ace angiotensin I converting enzyme decreases expression
multiple interactions		 ISO Bleomycin results in decreased expression of ACE protein
angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein]		 CTD PMID:20581171 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions
decreases expression		 ISO angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] CTD PMID:20581171 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta increases expression
multiple interactions
decreases expression		 EXP
ISO		 Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; celastrol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
Bleomycin results in decreased expression of ACTA2 protein
yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]		 CTD PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 More... NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990 		JBrowse link
G Actg1 actin, gamma, cytoplasmic 1 increases expression EXP Bleomycin results in increased expression of ACTG1 mRNA CTD PMID:36087614 NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368 		JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO Bleomycin results in decreased expression of ACTN1 protein CTD PMID:25933445 NCBI chr12:80,214,316...80,307,165
Ensembl chr12:80,214,321...80,307,145 		JBrowse link
G Actn4 actinin alpha 4 decreases expression ISO Bleomycin results in decreased expression of ACTN4 protein CTD PMID:25933445 NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765 		JBrowse link
G Actr10 ARP10 actin-related protein 10 increases expression EXP Bleomycin results in increased expression of ACTR10 mRNA CTD PMID:36087614 NCBI chr12:70,984,631...71,011,492
Ensembl chr12:70,984,631...71,011,492 		JBrowse link
G Actr3b ARP3 actin-related protein 3B increases expression EXP Bleomycin results in increased expression of ACTR3B mRNA CTD PMID:36087614 NCBI chr 5:25,964,960...26,055,686
Ensembl chr 5:25,964,995...26,055,686 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 multiple interactions EXP Bleomycin results in increased expression of and results in increased activity of ADAM17 protein CTD PMID:22687607 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adra1b adrenergic receptor, alpha 1b decreases expression ISO Bleomycin results in decreased expression of ADRA1B mRNA CTD PMID:15808516 NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression		 ISO protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] CTD PMID:25582705 PMID:25933445 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression
multiple interactions		 ISO Bleomycin results in increased expression of AGTR1 protein
angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein]		 CTD PMID:20581171 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression ISO Bleomycin results in increased expression of AHSG protein CTD PMID:25933445 NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 multiple interactions EXP 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]; Bleomycin affects the expression of and affects the localization of AIFM1 protein; Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein] CTD PMID:37783230 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation EXP Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607 PMID:26520185 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Alb albumin increases expression ISO Bleomycin results in increased expression of ALB protein CTD PMID:25933445 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 decreases expression ISO Bleomycin results in decreased expression of ALDH1A1 protein CTD PMID:25933445 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldoc aldolase C, fructose-bisphosphate multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein CTD PMID:29733421 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607 		JBrowse link
G Angptl3 angiopoietin-like 3 multiple interactions
increases expression		 EXP Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ANGPTL3 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ANGPTL3 protein] CTD PMID:30825431 NCBI chr 4:98,919,191...98,926,429
Ensembl chr 4:98,919,191...98,934,348 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression EXP Bleomycin results in increased expression of ANKRD1 mRNA CTD PMID:26345256 NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression ISO Bleomycin results in increased expression of ANP32E protein CTD PMID:25933445 NCBI chr 3:95,836,557...95,854,699
Ensembl chr 3:95,836,558...95,854,702 		JBrowse link
G Anxa2 annexin A2 decreases expression ISO Bleomycin results in decreased expression of ANXA2 protein CTD PMID:25933445 NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077 		JBrowse link
G Anxa3 annexin A3 decreases expression ISO Bleomycin results in decreased expression of ANXA3 protein CTD PMID:25933445 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825 		JBrowse link
G Anxa4 annexin A4 decreases expression ISO Bleomycin results in decreased expression of ANXA4 protein CTD PMID:25933445 NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566 		JBrowse link
G Anxa5 annexin A5 increases expression ISO Bleomycin results in increased expression of ANXA5 protein CTD PMID:25933445 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043 		JBrowse link
G Anxa6 annexin A6 decreases expression ISO Bleomycin results in decreased expression of ANXA6 protein CTD PMID:25933445 NCBI chr11:54,869,779...54,924,297
Ensembl chr11:54,869,934...54,924,271 		JBrowse link
G Anxa7 annexin A7 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201 		JBrowse link
G Aox2 aldehyde oxidase 2 increases expression EXP Bleomycin results in increased expression of AOX2 mRNA CTD PMID:36087614 NCBI chr 1:58,317,485...58,418,423
Ensembl chr 1:58,317,485...58,419,418 		JBrowse link
G Aqp1 aquaporin 1 decreases expression ISO Bleomycin results in decreased expression of AQP1 mRNA CTD PMID:15782499 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540 		JBrowse link
G Areg amphiregulin increases expression EXP Bleomycin results in increased expression of AREG mRNA CTD PMID:26817844 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291 		JBrowse link
G Arg1 arginase, liver increases expression
multiple interactions
decreases expression		 EXP Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ARG1 protein]		 CTD PMID:26345256 PMID:26526764 PMID:30825431 PMID:33647319 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression		 ISO pachymic acid inhibits the reaction [Bleomycin results in increased expression of ATF4 protein] CTD PMID:37163307 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
increases phosphorylation		 ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] CTD PMID:24933654 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO Bleomycin results in decreased expression of ATP5F1B protein CTD PMID:25933445 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression ISO Bleomycin results in increased expression of ATP5IF1 protein CTD PMID:25933445 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr 5:108,581,112...108,582,265
Ensembl chr 5:108,581,110...108,582,314 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression EXP Bleomycin results in decreased expression of ATP5PO protein CTD PMID:29733421 NCBI chr16:91,722,111...91,728,518
Ensembl chr16:91,722,102...91,728,575
Ensembl chr16:91,722,102...91,728,575 		JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of ATP6V1A protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein		 CTD PMID:29733421 NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression ISO Bleomycin results in decreased expression of AVPR1A mRNA CTD PMID:15808516 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Bleomycin results in increased expression of BASP1 protein CTD PMID:25933445 NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850 		JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases expression		 ISO
EXP		 allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]
Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein]		 CTD PMID:23656969 PMID:26093215 PMID:32278510 PMID:37783230 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA]
[Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]; Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]		 CTD PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624 		JBrowse link
G Bik BCL2-interacting killer increases expression EXP Bleomycin results in increased expression of BIK mRNA CTD PMID:36087614 NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance
increases expression		 ISO BIRC2 protein results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of BIRC2 protein		 CTD PMID:10815900 PMID:15371238 NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Bleomycin results in increased expression of BIRC5 mRNA CTD PMID:26345256 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Blmh bleomycin hydrolase affects response to substance ISO BLMH gene polymorphism affects the susceptibility to Bleomycin CTD PMID:12082022 NCBI chr11:76,836,482...76,878,215
Ensembl chr11:76,815,635...76,878,205 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression EXP Bleomycin results in decreased expression of BMP7 mRNA CTD PMID:29408570 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression EXP Bleomycin results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr19:8,814,831...8,826,047
Ensembl chr19:8,814,831...8,826,047 		JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide increases expression EXP Bleomycin results in increased expression of C1QB mRNA CTD PMID:26345256 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases expression EXP Bleomycin results in increased expression of CALCA mRNA CTD PMID:36087614 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Cald1 caldesmon 1 increases expression ISO Bleomycin results in increased expression of CALD1 protein CTD PMID:25933445 NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO Bleomycin results in decreased expression of CALML3 protein CTD PMID:25933445 NCBI chr13:3,852,893...3,854,318
Ensembl chr13:3,852,896...3,854,316 		JBrowse link
G Calr calreticulin increases expression ISO Bleomycin results in increased expression of CALR protein CTD PMID:25933445 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Calu calumenin increases expression ISO Bleomycin results in increased expression of CALU protein CTD PMID:25933445 NCBI chr 6:29,348,105...29,376,674
Ensembl chr 6:29,348,068...29,377,109 		JBrowse link
G Car1 carbonic anhydrase 1 decreases expression ISO Bleomycin results in decreased expression of CA1 protein CTD PMID:25933445 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression ISO Bleomycin results in decreased expression of CA2 protein CTD PMID:25933445 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 increases expression ISO Bleomycin results in increased expression of CARHSP1 protein CTD PMID:25933445 NCBI chr16:8,476,444...8,490,017
Ensembl chr16:8,476,444...8,490,019 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
increases cleavage		 ISO
EXP		 [Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA]
Bleomycin results in increased activity of CASP3 protein
Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA
Bleomycin results in increased cleavage of CASP3 protein
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]]; baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]		 CTD PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression		 ISO
EXP		 Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein; pachymic acid inhibits the reaction [Bleomycin results in increased expression of CASP9 protein]
Bleomycin results in increased activity of CASP9 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA		 CTD PMID:15371238 PMID:22687607 PMID:26800624 PMID:37163307 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cast calpastatin increases expression ISO Bleomycin results in increased expression of CAST protein CTD PMID:25933445 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Cat catalase increases response to substance
multiple interactions
increases expression
decreases activity		 ISO
EXP		 CAT protein results in increased susceptibility to Bleomycin
Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; Oils, Volatile inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
Bleomycin results in increased expression of CAT protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]
celastrol inhibits the reaction [Bleomycin results in decreased activity of CAT protein]; pachymic acid inhibits the reaction [Bleomycin results in decreased activity of CAT protein]		 CTD PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 PMID:28850077 More... NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cav1 caveolin 1, caveolae protein decreases expression
multiple interactions		 ISO Bleomycin results in decreased expression of CAV1 protein
Bleomycin results in decreased expression of CAV1 mRNA; Bleomycin results in decreased expression of CAV1 protein
yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 protein]		 CTD PMID:25933445 PMID:37898439 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Cavin2 caveolae associated 2 decreases expression ISO Bleomycin results in decreased expression of CAVIN2 protein CTD PMID:25933445 NCBI chr 1:51,328,285...51,342,119
Ensembl chr 1:51,328,285...51,342,119 		JBrowse link
G Cbx8 chromobox 8 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of CBX8 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA]		 CTD PMID:30825431 NCBI chr11:118,929,262...118,931,739
Ensembl chr11:118,927,131...118,931,795 		JBrowse link
G Cckar cholecystokinin A receptor decreases expression ISO Bleomycin results in decreased expression of CCKAR mRNA CTD PMID:15808516 NCBI chr 5:53,855,827...53,865,046
Ensembl chr 5:53,855,118...53,865,047 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
decreases response to substance
multiple interactions
decreases expression		 EXP Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein
CCL11 gene mutant form results in decreased susceptibility to Bleomycin
CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
Bleomycin results in decreased expression of CCL11 mRNA		 CTD PMID:16314464 PMID:29720568 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression
multiple interactions
decreases expression		 EXP Bleomycin results in increased expression of CCL12 mRNA
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA]
Bleomycin results in decreased expression of CCL12 mRNA		 CTD PMID:28434932 PMID:29720568 NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression EXP Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein CTD PMID:26345256 PMID:29175452 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
decreases expression		 EXP
ISO		 Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]
Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein
Bleomycin results in decreased expression of CCL2 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CCL2 protein		 CTD PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 More... NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Bleomycin results in increased expression of CCL3 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA]
Bleomycin results in decreased expression of CCL3 mRNA
Bleomycin results in decreased expression of CCL3 protein
[Bleomycin co-treated with Tobacco Smoke Pollution] affects the expression of CCL3 protein		 CTD PMID:26520185 PMID:29720568 PMID:32828905 PMID:33516805 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression EXP Bleomycin results in decreased expression of CCL4 mRNA CTD PMID:29720568 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of CCL5 mRNA
SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]		 CTD PMID:32828905 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 increases expression EXP Bleomycin results in increased expression of CCL6 protein CTD PMID:29175452 NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression EXP Bleomycin results in decreased expression of CCL7 mRNA CTD PMID:29720568 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351 		JBrowse link
G Ccl8 C-C motif chemokine ligand 8 decreases expression EXP Bleomycin results in decreased expression of CCL8 mRNA CTD PMID:29720568 NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression		 EXP [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]
Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein		 CTD PMID:19080365 PMID:26817844 PMID:27153807 PMID:28434932 PMID:32032644 More... NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP Bleomycin results in increased expression of CCNG1 mRNA CTD PMID:26345256 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases response to substance
increases expression		 EXP CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
CCR2 gene mutant form results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of CCR2 mRNA		 CTD PMID:14609568 PMID:29033951 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 increases expression EXP Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein CTD PMID:16314464 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 affects expression
multiple interactions
increases expression		 EXP Bleomycin affects the expression of CCR5 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA]		 CTD PMID:26345256 PMID:30825431 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr16:87,280,213...87,292,757
Ensembl chr16:87,280,214...87,292,761 		JBrowse link
G Cd14 CD14 antigen increases expression EXP Bleomycin results in increased expression of CD14 mRNA CTD PMID:36087614 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd2 CD2 antigen increases expression EXP Bleomycin results in increased expression of CD2 mRNA CTD PMID:36087614 NCBI chr 3:101,183,224...101,195,255
Ensembl chr 3:101,183,215...101,195,255 		JBrowse link
G Cd33 CD33 molecule multiple interactions
increases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA] CTD PMID:30825431 NCBI chr 7:43,176,823...43,186,679
Ensembl chr 7:43,173,640...43,193,852 		JBrowse link
G Cd34 CD34 antigen multiple interactions
decreases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CD34 protein] CTD PMID:30825431 NCBI chr 1:194,621,239...194,643,587
Ensembl chr 1:194,621,127...194,643,587 		JBrowse link
G Cd36 CD36 molecule decreases expression EXP Bleomycin results in decreased expression of CD36 mRNA CTD PMID:29408570 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd44 CD44 antigen increases expression
multiple interactions		 EXP Bleomycin results in increased expression of CD44 protein
honokiol inhibits the reaction [Bleomycin results in increased expression of CD44 protein]		 CTD PMID:32032644 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cd83 CD83 antigen increases expression EXP Bleomycin results in increased expression of CD83 mRNA CTD PMID:36087614 NCBI chr13:43,938,661...43,956,608
Ensembl chr13:43,938,251...43,956,608 		JBrowse link
G Cd86 CD86 antigen decreases expression EXP Bleomycin results in decreased expression of CD86 mRNA CTD PMID:29720568 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Cdc20 cell division cycle 20 increases expression EXP Bleomycin results in increased expression of CDC20 mRNA CTD PMID:26345256 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression		 EXP
ISO		 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; honokiol inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; pirfenidone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]
Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein		 CTD PMID:28300665 PMID:28694203 PMID:32032644 PMID:34425168 PMID:35472619 More... NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdh2 cadherin 2 multiple interactions
increases expression		 EXP OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein] CTD PMID:35654123 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression EXP Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256 PMID:29720568 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
decreases response to substance
multiple interactions
increases response to substance		 EXP Bleomycin results in increased expression of CEBPB mRNA
CEBPB gene mutant form results in decreased susceptibility to Bleomycin
CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]
CEBPB protein results in increased susceptibility to Bleomycin		 CTD PMID:17177178 PMID:21998664 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression ISO Bleomycin results in decreased expression of CEMIP2 mRNA CTD PMID:33770205 NCBI chr19:21,755,704...21,835,724
Ensembl chr19:21,755,706...21,835,724 		JBrowse link
G Cenpe centromere protein E multiple interactions
decreases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA] CTD PMID:30825431 NCBI chr 3:134,918,324...134,979,301
Ensembl chr 3:134,918,298...134,979,372 		JBrowse link
G Cert1 ceramide transporter 1 increases expression EXP Bleomycin results in increased expression of CERT1 mRNA CTD PMID:36087614 NCBI chr13:96,679,243...96,782,362
Ensembl chr13:96,679,243...96,776,675 		JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Cfl1 cofilin 1, non-muscle increases expression ISO Bleomycin results in increased expression of CFL1 protein CTD PMID:25933445 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions		 ISO Bleomycin results in increased phosphorylation of CHEK2 protein
resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein]		 CTD PMID:24933654 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Chil3 chitinase-like 3 increases expression EXP Bleomycin results in increased expression of CHIL3 protein CTD PMID:33647319 NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression ISO Bleomycin results in decreased expression of CHRNB2 mRNA CTD PMID:15808516 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939 		JBrowse link
G Ckb creatine kinase, brain increases expression ISO Bleomycin results in increased expression of CKB protein CTD PMID:25933445 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772 		JBrowse link
G Clcn5 chloride channel, voltage-sensitive 5 increases expression ISO Bleomycin results in increased expression of CLCN5 mRNA CTD PMID:15808516 NCBI chr  X:7,020,049...7,185,597
Ensembl chr  X:7,020,049...7,185,597 		JBrowse link
G Cldn4 claudin 4 increases expression EXP Bleomycin results in increased expression of CLDN4 mRNA CTD PMID:26345256 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788 		JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression ISO Bleomycin results in decreased expression of CLIC4 protein CTD PMID:25933445 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125 		JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression ISO Bleomycin results in decreased expression of CLIC5 protein CTD PMID:25933445 NCBI chr17:44,445,671...44,591,059
Ensembl chr17:44,445,659...44,591,059 		JBrowse link
G Cltc clathrin heavy chain decreases expression ISO Bleomycin results in decreased expression of CLTC protein CTD PMID:25933445 NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression ISO Bleomycin results in decreased expression of CNR1 mRNA CTD PMID:15808516 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Col11a2 collagen, type XI, alpha 2 increases expression EXP Bleomycin results in increased expression of COL11A2 mRNA CTD PMID:36087614 NCBI chr17:34,257,462...34,285,659
Ensembl chr17:34,258,411...34,285,659 		JBrowse link
G Col14a1 collagen, type XIV, alpha 1 increases expression EXP Bleomycin results in increased expression of COL14A1 mRNA CTD PMID:36087614 NCBI chr15:55,171,040...55,384,199
Ensembl chr15:55,171,146...55,384,199 		JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 increases expression EXP Bleomycin results in increased expression of COL18A1 mRNA CTD PMID:36087614 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382 		JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions
increases expression
decreases expression		 EXP
ISO		 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; [Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein
Bleomycin results in decreased expression of COL1A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]		 CTD PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 More... NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col1a2 collagen, type I, alpha 2 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Bleomycin results in increased expression of COL1A2 mRNA; Bleomycin results in increased expression of COL1A2 protein
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of COL1A2 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]
Bleomycin results in decreased expression of COL1A2 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein]		 CTD PMID:19147827 PMID:25933445 PMID:35472619 PMID:37163307 PMID:37307957 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544 		JBrowse link
G Col22a1 collagen, type XXII, alpha 1 increases expression EXP Bleomycin results in increased expression of COL22A1 mRNA CTD PMID:36087614 NCBI chr15:71,667,644...71,906,087
Ensembl chr15:71,667,644...71,906,076 		JBrowse link
G Col24a1 collagen, type XXIV, alpha 1 increases expression EXP Bleomycin results in increased expression of COL24A1 mRNA CTD PMID:36087614 NCBI chr 3:144,998,233...145,257,768
Ensembl chr 3:144,998,233...145,257,766 		JBrowse link
G Col3a1 collagen, type III, alpha 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Bleomycin results in decreased expression of COL3A1 protein
Bleomycin results in increased expression of COL3A1 mRNA; Bleomycin results in increased expression of COL3A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]
honokiol inhibits the reaction [Bleomycin results in increased expression of COL3A1 protein]		 CTD PMID:25933445 PMID:26817844 PMID:28726637 PMID:32032644 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866 		JBrowse link
G Col4a4 collagen, type IV, alpha 4 increases expression EXP Bleomycin results in increased expression of COL4A4 mRNA CTD PMID:36087614 NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570 		JBrowse link
G Col5a1 collagen, type V, alpha 1 decreases expression
increases expression		 ISO
EXP		 Bleomycin results in decreased expression of COL5A1 protein
Bleomycin results in increased expression of COL5A1 mRNA		 CTD PMID:25933445 PMID:36087614 NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526 		JBrowse link
G Col5a2 collagen, type V, alpha 2 increases expression EXP Bleomycin results in increased expression of COL5A2 mRNA CTD PMID:36087614 NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442 		JBrowse link
G Col5a3 collagen, type V, alpha 3 increases expression EXP Bleomycin results in increased expression of COL5A3 mRNA CTD PMID:36087614 NCBI chr 9:20,681,353...20,726,363
Ensembl chr 9:20,681,346...20,726,363 		JBrowse link
G Col6a3 collagen, type VI, alpha 3 increases expression EXP Bleomycin results in increased expression of COL6A3 mRNA CTD PMID:36087614 NCBI chr 1:90,694,582...90,771,710
Ensembl chr 1:90,693,645...90,771,693 		JBrowse link
G Col9a2 collagen, type IX, alpha 2 increases expression EXP Bleomycin results in increased expression of COL9A2 mRNA CTD PMID:36087614 NCBI chr 4:120,896,763...120,912,522
Ensembl chr 4:120,896,582...120,912,519 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression EXP Bleomycin results in increased expression of COLQ mRNA CTD PMID:36087614 NCBI chr14:31,245,039...31,299,820
Ensembl chr14:31,245,039...31,313,300 		JBrowse link
G Comp cartilage oligomeric matrix protein multiple interactions EXP [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein CTD PMID:29033951 NCBI chr 8:70,826,186...70,834,721
Ensembl chr 8:70,826,208...70,834,716 		JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression		 EXP tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] CTD PMID:12624602 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309 		JBrowse link
G Crip2 cysteine rich protein 2 affects expression ISO Bleomycin affects the expression of CRIP2 protein CTD PMID:25933445 NCBI chr12:113,103,856...113,109,126
Ensembl chr12:113,103,856...113,109,126 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) increases expression
decreases expression		 ISO
EXP		 Bleomycin results in increased expression of CSF2 protein
Bleomycin results in decreased expression of CSF2 mRNA		 CTD PMID:18684396 PMID:29720568 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) increases expression EXP Bleomycin results in increased expression of CSF2RB2 mRNA CTD PMID:36087614 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) decreases expression ISO Bleomycin results in decreased expression of CSF3 mRNA CTD PMID:15808516 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression ISO Bleomycin results in increased expression of CSRP1 protein CTD PMID:25933445 NCBI chr 1:135,614,650...135,679,970
Ensembl chr 1:135,647,799...135,679,970 		JBrowse link
G Ctsa cathepsin A affects expression EXP Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 NCBI chr 2:164,674,792...164,682,952
Ensembl chr 2:164,674,793...164,682,952 		JBrowse link
G Ctsb cathepsin B affects expression EXP Bleomycin affects the expression of CTSB mRNA CTD PMID:26345256 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372 		JBrowse link
G Ctsh cathepsin H affects expression EXP Bleomycin affects the expression of CTSH mRNA CTD PMID:26345256 NCBI chr 9:89,936,320...89,958,148
Ensembl chr 9:89,936,205...89,958,142 		JBrowse link
G Ctss cathepsin S increases expression ISO Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of CX3CL1 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of CX3CL1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CX3CL1 protein]		 CTD PMID:30825431 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Bleomycin results in increased expression of CXCL10 mRNA; Bleomycin results in increased expression of CXCL10 protein
Bleomycin results in decreased expression of CXCL10 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL10 protein		 CTD PMID:26345256 PMID:29720568 PMID:33516805 PMID:36087614 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP Bleomycin results in increased expression of CXCL12 mRNA CTD PMID:29720568 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression EXP Bleomycin affects the expression of CXCL13 mRNA CTD PMID:26345256 NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression EXP Bleomycin results in increased expression of CXCL14 mRNA CTD PMID:36087614 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases expression		 ISO [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of CXCL8 protein
Bleomycin results in increased expression of CXCL8 mRNA; Bleomycin results in increased expression of CXCL8 protein		 CTD PMID:14617519 PMID:18684396 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions		 ISO
EXP		 Bleomycin results in increased expression of CXCL2 protein
Bleomycin results in increased secretion of CXCL2 protein
Bleomycin results in increased expression of CXCL2 mRNA
3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL2 protein		 CTD PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 PMID:33516805 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases secretion
increases expression		 EXP TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]
Bleomycin results in increased expression of CXCL1 protein		 CTD PMID:26600069 PMID:36087614 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression EXP Bleomycin results in increased expression of CXCL9 protein CTD PMID:29175452 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression EXP Bleomycin results in increased expression of CXCR1 mRNA CTD PMID:36087614 NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790 		JBrowse link
G Cyba cytochrome b-245, alpha polypeptide multiple interactions
increases expression		 EXP Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of CYBA mRNA] CTD PMID:35187969 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669 		JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Bleomycin affects the localization of CYCS protein CTD PMID:15371238 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Dbi diazepam binding inhibitor increases expression ISO Bleomycin results in increased expression of DBI protein CTD PMID:25933445 NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO pachymic acid inhibits the reaction [Bleomycin results in increased expression of DDIT3 protein] CTD PMID:37163307 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Des desmin increases expression ISO Bleomycin results in increased expression of DES protein CTD PMID:25933445 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression EXP Bleomycin results in decreased expression of DLAT protein CTD PMID:29733421 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080 		JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression ISO
EXP		 Bleomycin results in increased expression of DLD protein CTD PMID:25933445 PMID:29733421 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression EXP Bleomycin results in increased expression of DLK1 protein CTD PMID:29175452 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of DLL4 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of DLL4 protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of DLL4 protein]		 CTD PMID:30825431 NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443 		JBrowse link
G Dnm1l dynamin 1-like increases expression EXP Bleomycin results in increased expression of DNM1L protein CTD PMID:37126650 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dpep1 dipeptidase 1 decreases expression ISO Bleomycin results in decreased expression of DPEP1 protein CTD PMID:25933445 NCBI chr 8:123,913,069...123,928,551
Ensembl chr 8:123,912,981...123,928,551 		JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal decreases expression ISO Bleomycin results in decreased expression of ECH1 protein CTD PMID:25933445 NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 ISO Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression EXP Bleomycin results in increased expression of EEF1A1 protein CTD PMID:29733421 NCBI chr 9:78,385,735...78,389,006
Ensembl chr 9:78,385,731...78,396,433 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
affects expression		 EXP Bleomycin results in increased expression of EGR1 mRNA
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA]
Bleomycin affects the expression of EGR1 mRNA		 CTD PMID:19147827 PMID:26345256 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Egr2 early growth response 2 affects expression EXP Bleomycin affects the expression of EGR2 mRNA CTD PMID:26345256 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018 		JBrowse link
G Ehd1 EH-domain containing 1 decreases expression ISO Bleomycin results in decreased expression of EHD1 protein CTD PMID:25933445 NCBI chr19:6,326,926...6,350,126
Ensembl chr19:6,326,755...6,350,126 		JBrowse link
G Ehd2 EH-domain containing 2 decreases expression ISO Bleomycin results in decreased expression of EHD2 protein CTD PMID:25933445 NCBI chr 7:15,680,883...15,701,402
Ensembl chr 7:15,680,883...15,701,492 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression ISO Bleomycin results in increased expression of EIF5A protein CTD PMID:25933445 NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784 		JBrowse link
G Eln elastin increases expression EXP Bleomycin results in increased expression of ELN mRNA CTD PMID:26817844 NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177 		JBrowse link
G Emcn endomucin increases expression
multiple interactions		 EXP Bleomycin results in increased expression of EMCN mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA]		 CTD PMID:30825431 NCBI chr 3:137,046,824...137,136,830
Ensembl chr 3:137,046,828...137,137,946 		JBrowse link
G Eng endoglin multiple interactions
increases expression		 EXP Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ENG protein] CTD PMID:30825431 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Epx eosinophil peroxidase increases expression ISO Bleomycin results in increased expression of EPX protein CTD PMID:26093215 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO Bleomycin results in decreased expression of ERRFI1 mRNA CTD PMID:33770205 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349 		JBrowse link
G Espl1 extra spindle pole bodies 1, separase decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of ESPL1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA]		 CTD PMID:30825431 NCBI chr15:102,204,688...102,232,792
Ensembl chr15:102,204,701...102,232,792 		JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain decreases expression EXP Bleomycin results in decreased expression of ETS1 mRNA CTD PMID:28726637 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116 		JBrowse link
G Ets2 E26 avian leukemia oncogene 2, 3' domain decreases expression EXP Bleomycin results in decreased expression of ETS2 mRNA CTD PMID:28726637 NCBI chr16:95,503,274...95,522,093
Ensembl chr16:95,502,942...95,522,095 		JBrowse link
G Ezr ezrin decreases expression ISO Bleomycin results in decreased expression of EZR protein CTD PMID:25933445 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression		 ISO allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein]
Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein		 CTD PMID:23656969 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735 		JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression EXP Bleomycin results in decreased expression of FABP4 mRNA CTD PMID:29408570 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636 		JBrowse link
G Fasl Fas ligand increases expression EXP Bleomycin results in increased expression of FASLG mRNA CTD PMID:11350791 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions
increases expression		 EXP Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF1 protein] CTD PMID:30825431 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
multiple interactions		 ISO
EXP		 Bleomycin results in increased expression of FGF2 protein
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF2 protein]		 CTD PMID:25582705 PMID:30825431 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions
decreases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of FGF21 protein] CTD PMID:30825431 NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of FGF7 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF7 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of FGF7 protein]		 CTD PMID:30825431 NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression ISO Bleomycin results in increased expression of FHL1 protein CTD PMID:25933445 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706 		JBrowse link
G Fkbp10 FK506 binding protein 10 increases expression EXP Bleomycin results in increased expression of FKBP10 mRNA CTD PMID:36087614 NCBI chr11:100,306,520...100,315,666
Ensembl chr11:100,306,523...100,315,650 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 ISO
EXP		 Bleomycin results in increased expression of FN1 protein
[Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]; TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]
Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of FN1 protein]		 CTD PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 More... NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Fos FBJ osteosarcoma oncogene increases activity
multiple interactions		 EXP Bleomycin results in increased activity of FOS protein
Bleomycin results in increased expression of [JUN protein binds to FOS protein]		 CTD PMID:12003776 PMID:37399107 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Foxp3 forkhead box P3 increases expression EXP Bleomycin results in increased expression of FOXP3 mRNA CTD PMID:29033951 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Foxq1 forkhead box Q1 increases expression EXP Bleomycin results in increased expression of FOXQ1 mRNA CTD PMID:36087614 NCBI chr13:31,742,153...31,744,959
Ensembl chr13:31,740,117...31,744,959 		JBrowse link
G Foxr1 forkhead box R1 increases expression EXP Bleomycin results in increased expression of FOXR1 mRNA CTD PMID:36087614 NCBI chr 9:44,345,531...44,352,165
Ensembl chr 9:44,345,070...44,352,433 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO Bleomycin results in decreased expression of FSHR mRNA CTD PMID:15808516 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103 		JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 increases expression ISO Bleomycin results in increased expression of FUBP1 protein CTD PMID:25933445 NCBI chr 3:151,916,059...151,942,467
Ensembl chr 3:151,916,059...151,942,463 		JBrowse link
G Fzd6 frizzled class receptor 6 increases expression
multiple interactions		 EXP
ISO		 Bleomycin results in increased expression of FZD6 mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]		 CTD PMID:28726637 NCBI chr15:38,869,673...38,901,587
Ensembl chr15:38,869,429...38,901,583 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression ISO Bleomycin results in decreased expression of GABRA4 mRNA CTD PMID:15808516 NCBI chr 5:71,727,077...71,815,651
Ensembl chr 5:71,727,092...71,815,651 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression ISO Bleomycin results in decreased expression of GABRB2 mRNA CTD PMID:15808516 NCBI chr11:42,310,342...42,523,418
Ensembl chr11:42,310,584...42,519,855 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor, subunit gamma 2 decreases expression ISO Bleomycin results in decreased expression of GABRG2 mRNA CTD PMID:15808516 NCBI chr11:41,801,017...41,891,684
Ensembl chr11:41,801,030...41,891,684 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression ISO Bleomycin results in decreased expression of GABRR1 mRNA CTD PMID:15808516 NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588 		JBrowse link
G Ganab alpha glucosidase 2 alpha neutral subunit multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein CTD PMID:29733421 NCBI chr19:8,875,440...8,894,098
Ensembl chr19:8,875,435...8,894,036 		JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP Bleomycin results in increased expression of GAS6 protein CTD PMID:29175452 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490 		JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of GATA3 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]		 CTD PMID:29033951 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gc vitamin D binding protein increases expression ISO Bleomycin results in increased expression of GC protein CTD PMID:25933445 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression		 EXP caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gda guanine deaminase decreases expression ISO Bleomycin results in decreased expression of GDA protein CTD PMID:25933445 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 decreases expression ISO Bleomycin results in decreased expression of GPI protein CTD PMID:25933445 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression ISO Bleomycin affects the expression of GPX1 protein CTD PMID:25933445 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) decreases expression ISO Bleomycin results in decreased expression of GRIA2 mRNA CTD PMID:15808516 NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142 		JBrowse link
G Grik3 glutamate receptor, ionotropic, kainate 3 decreases expression ISO Bleomycin results in decreased expression of GRIK3 mRNA CTD PMID:15808516 NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966 		JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression ISO Bleomycin results in decreased expression of GRPR mRNA CTD PMID:15808516 NCBI chr  X:162,296,900...162,332,732
Ensembl chr  X:162,296,900...162,332,673 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation		 ISO [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsn gelsolin decreases expression ISO Bleomycin results in decreased expression of GSN protein CTD PMID:25933445 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G Gsr glutathione reductase decreases activity
multiple interactions		 ISO Bleomycin results in decreased activity of GSR protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of GSR protein]		 CTD PMID:26768587 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 decreases expression ISO Bleomycin results in decreased expression of GSTM1 protein CTD PMID:25933445 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G H1f0 H1.0 linker histone affects expression ISO Bleomycin affects the expression of H1F0 protein CTD PMID:25933445 NCBI chr15:78,912,412...78,914,704
Ensembl chr15:78,912,650...78,914,704 		JBrowse link
G H1f4 H1.4 linker histone, cluster member affects expression ISO Bleomycin affects the expression of H1F4 protein CTD PMID:25933445 NCBI chr13:23,805,760...23,806,541
Ensembl chr13:23,804,612...23,806,541 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO Bleomycin results in decreased expression of HADHA protein CTD PMID:25933445 NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP Bleomycin results in increased expression of HAVCR1 protein CTD PMID:29175452 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain affects expression ISO Bleomycin affects the expression of HBB protein CTD PMID:25933445
G Hbb-b2 hemoglobin, beta adult minor chain affects expression ISO Bleomycin affects the expression of HBB-B2 protein CTD PMID:25933445
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Bleomycin results in increased expression of HBEGF mRNA CTD PMID:18684396 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 multiple interactions
increases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA] CTD PMID:30825431 NCBI chr16:36,755,345...36,783,576
Ensembl chr16:36,755,345...36,783,574 		JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
increases secretion
increases expression		 ISO
EXP		 Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein
Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein]
Bleomycin results in increased secretion of HGF protein
Bleomycin results in increased expression of HGF mRNA
Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of HGF protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of HGF protein]		 CTD PMID:16115399 PMID:22687607 PMID:29408570 PMID:30825431 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression
multiple interactions		 EXP Bleomycin results in increased expression of HIF1A mRNA
[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]		 CTD PMID:28434932 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmces 5-hydroxymethylcytosine (hmC) binding, ES cell specific decreases expression ISO Bleomycin results in decreased expression of HMCES mRNA CTD PMID:33770205 NCBI chr 6:87,890,889...87,913,603
Ensembl chr 6:87,890,917...87,913,611 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression		 ISO
EXP		 protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]		 CTD PMID:25582705 PMID:32278510 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmgb1-ps1 high mobility group box 1, pseudogene 1 increases expression EXP Bleomycin results in increased expression of HMGB1-PS1 mRNA CTD PMID:36087614 NCBI chr11:41,032,485...41,034,809
Ensembl chr11:41,032,590...41,033,223 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Bleomycin results in increased expression of HMOX1 protein
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]
Bleomycin results in increased expression of HMOX1 mRNA
Bleomycin results in decreased expression of HMOX1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]		 CTD PMID:16317386 PMID:26093215 PMID:26768587 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression ISO Bleomycin results in increased expression of HNRNPA2B1 protein CTD PMID:25933445 NCBI chr 6:51,437,414...51,448,054
Ensembl chr 6:51,437,912...51,446,874 		JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 increases expression ISO Bleomycin results in increased expression of HNRNPA3 protein CTD PMID:25933445 NCBI chr 2:75,489,416...75,499,751
Ensembl chr 2:75,489,605...75,499,751 		JBrowse link
G Hpx hemopexin increases expression ISO Bleomycin results in increased expression of HPX protein CTD PMID:25933445 NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa1a heat shock protein 1A multiple interactions
increases expression		 EXP geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1A mRNA] CTD PMID:37307957 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1b heat shock protein 1B increases expression
multiple interactions		 EXP Bleomycin results in increased expression of HSPA1B mRNA
geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1B mRNA]		 CTD PMID:37307957 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Hspa5 heat shock protein 5 increases expression
multiple interactions		 ISO Bleomycin results in increased expression of HSPA5 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of HSPA5 protein]		 CTD PMID:25933445 PMID:37163307 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspb1 heat shock protein 1 decreases expression ISO Bleomycin results in decreased expression of HSPB1 protein CTD PMID:25933445 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) increases expression ISO
EXP		 Bleomycin results in increased expression of HSPE1 protein CTD PMID:25933445 PMID:29733421 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466 		JBrowse link
G Htr1f 5-hydroxytryptamine (serotonin) receptor 1F decreases expression ISO Bleomycin results in decreased expression of HTR1F mRNA CTD PMID:15808516 NCBI chr16:64,745,092...64,926,147
Ensembl chr16:64,745,092...64,926,217 		JBrowse link
G Htr5a 5-hydroxytryptamine (serotonin) receptor 5A decreases expression ISO Bleomycin results in decreased expression of HTR5A mRNA CTD PMID:15808516 NCBI chr 5:28,046,836...28,059,403
Ensembl chr 5:28,047,147...28,060,086 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B decreases expression ISO Bleomycin results in decreased expression of HTR5B mRNA CTD PMID:15808516 NCBI chr 1:121,437,487...121,458,351
Ensembl chr 1:121,437,571...121,456,194 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression EXP Bleomycin results in increased expression of ICAM1 mRNA CTD PMID:29033951 PMID:29720568 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial decreases expression ISO Bleomycin results in decreased expression of IDH2 protein CTD PMID:25933445 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of IFITM1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA]		 CTD PMID:30825431 NCBI chr 7:140,547,342...140,549,740
Ensembl chr 7:140,547,134...140,549,738 		JBrowse link
G Ifng interferon gamma increases expression
decreases expression
multiple interactions		 EXP
ISO		 Bleomycin results in increased expression of IFNG mRNA
Bleomycin results in decreased expression of IFNG mRNA
[SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG protein
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IFNG protein		 CTD PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 PMID:33516805 More... NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP Bleomycin results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Ikbip IKBKB interacting protein increases expression EXP Bleomycin results in increased expression of IKBIP mRNA CTD PMID:36087614 NCBI chr10:90,918,667...90,938,475
Ensembl chr10:90,918,802...90,938,469 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
increases secretion		 EXP
ISO		 Bleomycin results in increased expression of IL10 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL10 protein]		 CTD PMID:29175452 PMID:37898439 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il10ra interleukin 10 receptor, alpha increases expression EXP Bleomycin results in increased expression of IL10RA mRNA CTD PMID:36087614 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447 		JBrowse link
G Il12b interleukin 12b increases expression EXP Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 increases expression EXP Bleomycin results in increased expression of IL12RB2 mRNA CTD PMID:11350791 NCBI chr 6:67,263,914...67,353,277
Ensembl chr 6:67,268,302...67,353,172 		JBrowse link
G Il13 interleukin 13 decreases response to substance
multiple interactions		 EXP IL13 gene mutant form results in decreased susceptibility to Bleomycin
IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]		 CTD PMID:15322207 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of IL13RA1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA]		 CTD PMID:30825431 PMID:36087614 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression		 EXP Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA] CTD PMID:35716765 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP Bleomycin results in increased expression of IL17RD mRNA CTD PMID:36087614 NCBI chr14:26,760,990...26,829,243
Ensembl chr14:26,760,898...26,829,243 		JBrowse link
G Il17re interleukin 17 receptor E increases expression EXP Bleomycin results in increased expression of IL17RE mRNA CTD PMID:36087614 NCBI chr 6:113,435,659...113,447,719
Ensembl chr 6:113,435,445...113,447,719 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression		 ISO
EXP		 IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1A protein		 CTD PMID:8317554 PMID:29175452 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion
affects expression		 EXP
ISO		 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of IL1B mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of IL1B mRNA; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]
Bleomycin affects the expression of IL1B mRNA		 CTD PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression EXP Bleomycin results in increased expression of IL1RL1 mRNA; Bleomycin results in increased expression of IL1RL1 protein CTD PMID:37399107 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IL2 protein CTD PMID:33516805 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il33 interleukin 33 increases expression EXP Bleomycin results in increased expression of IL33 mRNA; Bleomycin results in increased expression of IL33 protein CTD PMID:36087614 PMID:37399107 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Il4 interleukin 4 increases expression
decreases response to substance
multiple interactions
affects response to substance
increases secretion		 EXP
ISO		 Bleomycin results in increased expression of IL4 mRNA
IL4 gene mutant form results in decreased susceptibility to Bleomycin
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]; IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]
IL4 protein affects the susceptibility to Bleomycin
Bleomycin results in increased secretion of IL4 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL4 protein]		 CTD PMID:11554783 PMID:12574379 PMID:15322207 PMID:30033591 PMID:37898439 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO
EXP		 Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein]		 CTD PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il7 interleukin 7 increases expression EXP Bleomycin results in increased expression of IL7 protein CTD PMID:36087614 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of INSIG1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA]		 CTD PMID:30825431 NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660 		JBrowse link
G Itgb2 integrin beta 2 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of ITGB2 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA]		 CTD PMID:30825431 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression ISO Bleomycin results in increased expression of JPT1 protein CTD PMID:25933445 NCBI chr11:115,388,171...115,405,219
Ensembl chr11:115,388,179...115,405,213 		JBrowse link
G Jun jun proto-oncogene increases activity
multiple interactions
increases phosphorylation		 EXP Bleomycin results in increased activity of JUN protein
Bleomycin results in increased expression of [JUN protein binds to FOS protein]; Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein]		 CTD PMID:12003776 PMID:35716765 PMID:37399107 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 decreases expression
multiple interactions		 ISO Bleomycin results in decreased expression of KEAP1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein]		 CTD PMID:26768587 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression ISO Bleomycin results in increased expression of KHSRP protein CTD PMID:25933445 NCBI chr17:57,328,049...57,338,507
Ensembl chr17:57,328,051...57,338,522 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions		 EXP Bleomycin results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein		 CTD PMID:29733421 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kl klotho decreases expression EXP Bleomycin results in decreased expression of KL mRNA CTD PMID:29408570 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282 		JBrowse link
G Klhl42 kelch-like 42 increases expression ISO Bleomycin results in increased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 6:146,990,783...147,014,276
Ensembl chr 6:146,992,877...147,014,276 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions EXP [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene CTD PMID:12616606 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Krt13 keratin 13 increases expression EXP Bleomycin results in increased expression of KRT13 mRNA CTD PMID:36087614 NCBI chr11:100,008,153...100,012,392
Ensembl chr11:100,008,153...100,012,392 		JBrowse link
G Krt19 keratin 19 decreases expression ISO Bleomycin results in decreased expression of KRT19 protein CTD PMID:25933445 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491 		JBrowse link
G Krt87 keratin 87 increases expression EXP Bleomycin results in increased expression of KRT87 mRNA CTD PMID:36087614 NCBI chr15:101,329,371...101,336,685
Ensembl chr15:101,328,919...101,336,685 		JBrowse link
G Lap3 leucine aminopeptidase 3 increases expression ISO Bleomycin results in increased expression of LAP3 protein CTD PMID:25933445 NCBI chr 5:45,650,716...45,670,033
Ensembl chr 5:45,650,716...45,670,033 		JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO Bleomycin results in increased expression of LASP1 protein CTD PMID:25933445 NCBI chr11:97,689,748...97,729,591
Ensembl chr11:97,689,826...97,729,590 		JBrowse link
G Lcn2 lipocalin 2 increases expression EXP Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein CTD PMID:26345256 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of LCP1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA]		 CTD PMID:30825431 NCBI chr14:75,368,570...75,468,282
Ensembl chr14:75,368,541...75,468,282 		JBrowse link
G Lep leptin increases expression EXP Bleomycin results in increased expression of LEP protein CTD PMID:29175452 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 multiple interactions
increases expression		 EXP NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein] CTD PMID:26526764 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of LGALS9 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA]		 CTD PMID:30825431 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772 		JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of LHFPL6 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA]		 CTD PMID:30825431 NCBI chr 3:52,948,968...53,169,100
Ensembl chr 3:52,948,949...53,169,100 		JBrowse link
G Lhx1 LIM homeobox protein 1 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA CTD PMID:29733421 NCBI chr11:84,408,801...84,416,360
Ensembl chr11:84,409,110...84,416,361 		JBrowse link
G Liph lipase, member H decreases expression ISO Bleomycin results in decreased expression of LIPH mRNA CTD PMID:33770205 NCBI chr16:21,772,567...21,814,408
Ensembl chr16:21,772,567...21,814,413 		JBrowse link
G Lmna lamin A increases expression ISO Bleomycin results in increased expression of LMNA protein CTD PMID:25933445 NCBI chr 3:88,388,455...88,413,842
Ensembl chr 3:88,387,454...88,417,263 		JBrowse link
G Lpxn leupaxin multiple interactions
increases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA] CTD PMID:30825431 NCBI chr19:12,773,251...12,811,177
Ensembl chr19:12,773,557...12,811,171 		JBrowse link
G Lyz2 lysozyme 2 decreases expression ISO Bleomycin results in decreased expression of LYZ protein CTD PMID:25933445 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression ISO Bleomycin results in decreased expression of MACROH2A1 protein CTD PMID:25933445 NCBI chr13:56,221,435...56,283,439
Ensembl chr13:56,221,432...56,284,174 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions		 EXP Bleomycin results in increased expression of MAP1LC3B protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form]		 CTD PMID:31302203 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23570914 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23570914 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 EXP Bleomycin results in increased phosphorylation of MAPK8 protein
Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein]		 CTD PMID:35716765 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Bleomycin results in decreased expression of MARCKS protein CTD PMID:25933445 NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916 		JBrowse link
G Mdh2 malate dehydrogenase 2, NAD (mitochondrial) decreases expression
multiple interactions		 ISO
EXP		 Bleomycin results in decreased expression of MDH2 protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein		 CTD PMID:25933445 PMID:29733421 NCBI chr 5:135,807,503...135,819,240
Ensembl chr 5:135,807,334...135,819,252 		JBrowse link
G Mecp2 methyl CpG binding protein 2 affects response to substance EXP MECP2 protein affects the susceptibility to Bleomycin CTD PMID:21435439 NCBI chr  X:73,070,198...73,129,296
Ensembl chr  X:73,070,198...73,129,296 		JBrowse link
G Mepce methylphosphate capping enzyme increases expression ISO Bleomycin results in increased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr 5:137,780,168...137,785,915
Ensembl chr 5:137,780,168...137,785,917 		JBrowse link
G Mertk MER proto-oncogene tyrosine kinase multiple interactions
increases phosphorylation		 EXP Bleomycin affects the localization of and affects the expression of MERTK protein
Bleomycin results in increased phosphorylation of MERTK protein		 CTD PMID:22687607 NCBI chr 2:128,540,836...128,645,082
Ensembl chr 2:128,540,876...128,644,814 		JBrowse link
G Mfn1 mitofusin 1 decreases expression EXP Bleomycin results in decreased expression of MFN1 protein CTD PMID:37126650 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388 		JBrowse link
G Mfn2 mitofusin 2 decreases expression EXP Bleomycin results in decreased expression of MFN2 protein CTD PMID:37126650 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) decreases expression ISO Bleomycin results in decreased expression of MIF protein CTD PMID:25933445 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir100 microRNA 100 decreases expression ISO Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 NCBI chr 9:41,442,721...41,442,800
Ensembl chr 9:41,442,721...41,442,800 		JBrowse link
G Mir100hg Mir100 Mirlet7a-2 Mir125b-1 cluster host gene increases expression
multiple interactions		 EXP Bleomycin results in increased expression of MIR100HG mRNA
MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of COL1A2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM protein]		 CTD PMID:35472619 NCBI chr 9:41,287,822...41,526,481
Ensembl chr 9:41,238,373...41,628,290 		JBrowse link
G Mir101a microRNA 101a decreases expression
multiple interactions		 EXP
ISO		 Bleomycin results in decreased expression of MIR101A mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]		 CTD PMID:25933445 PMID:28726637 NCBI chr 4:101,204,142...101,204,224
Ensembl chr 4:101,204,142...101,204,224 		JBrowse link
G Mir101b microRNA 101b decreases expression ISO
EXP		 Bleomycin results in decreased expression of MIR101B mRNA CTD PMID:25933445 PMID:28726637 NCBI chr19:29,112,679...29,112,775
Ensembl chr19:29,112,679...29,112,775 		JBrowse link
G Mir106b microRNA 106b affects expression ISO Bleomycin affects the expression of MIR106B mRNA CTD PMID:25933445 NCBI chr 5:138,163,999...138,164,080
Ensembl chr 5:138,163,999...138,164,080 		JBrowse link
G Mir107 microRNA 107 decreases expression ISO Bleomycin results in decreased expression of MIR107 mRNA CTD PMID:25933445 NCBI chr19:34,798,087...34,798,173
Ensembl chr19:34,798,087...34,798,173 		JBrowse link
G Mir10a microRNA 10a decreases expression ISO Bleomycin results in decreased expression of MIR10A mRNA CTD PMID:25933445 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100 		JBrowse link
G Mir10b microRNA 10b decreases expression ISO Bleomycin results in decreased expression of MIR10B mRNA CTD PMID:25933445 NCBI chr 2:74,556,414...74,556,481
Ensembl chr 2:74,556,414...74,556,481 		JBrowse link
G Mir1224 microRNA 1224 increases expression ISO Bleomycin results in increased expression of MIR1224 mRNA CTD PMID:25933445 NCBI chr16:20,423,202...20,423,286
Ensembl chr16:20,423,202...20,423,286 		JBrowse link
G Mir1249 microRNA 1249 affects expression ISO Bleomycin affects the expression of MIR1249 mRNA CTD PMID:25933445 NCBI chr15:84,835,727...84,835,824
Ensembl chr15:84,835,727...84,835,824 		JBrowse link
G Mir125a microRNA 125a affects expression ISO Bleomycin affects the expression of MIR125A mRNA CTD PMID:25933445 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141 		JBrowse link
G Mir126a microRNA 126a decreases expression ISO Bleomycin results in decreased expression of MIR126 mRNA CTD PMID:25933445 NCBI chr 2:26,481,369...26,481,441
Ensembl chr 2:26,481,369...26,481,441 		JBrowse link
G Mir130a microRNA 130a decreases expression ISO Bleomycin results in decreased expression of MIR130A mRNA CTD PMID:25933445 NCBI chr 2:84,571,459...84,571,522
Ensembl chr 2:84,571,459...84,571,522 		JBrowse link
G Mir133a-1 microRNA 133a-1 decreases expression ISO Bleomycin results in decreased expression of MIR133A1 mRNA CTD PMID:25933445 NCBI chr18:10,782,909...10,782,976
Ensembl chr18:10,782,909...10,782,976 		JBrowse link
G Mir133b microRNA 133b decreases expression ISO Bleomycin results in decreased expression of MIR133B mRNA CTD PMID:25933445 NCBI chr 1:20,752,993...20,753,111
Ensembl chr 1:20,752,993...20,753,111 		JBrowse link
G Mir140 microRNA 140 affects expression ISO Bleomycin affects the expression of MIR140 mRNA CTD PMID:25933445 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945 		JBrowse link
G Mir141 microRNA 141 affects expression ISO Bleomycin affects the expression of MIR141 mRNA CTD PMID:25933445 NCBI chr 6:124,694,877...124,694,948
Ensembl chr 6:124,694,877...124,694,948 		JBrowse link
G Mir142 microRNA 142 increases expression
decreases expression		 ISO Bleomycin results in increased expression of MIR142 mRNA
Bleomycin results in decreased expression of MIR142 mRNA		 CTD PMID:25933445 NCBI chr11:87,647,690...87,647,753
Ensembl chr11:87,647,690...87,647,753 		JBrowse link
G Mir143 microRNA 143 decreases expression ISO Bleomycin results in decreased expression of MIR143 mRNA CTD PMID:25933445 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329 		JBrowse link
G Mir144 microRNA 144 decreases expression ISO Bleomycin results in decreased expression of MIR144 mRNA CTD PMID:25933445 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896 		JBrowse link
G Mir145a microRNA 145a decreases expression ISO Bleomycin results in decreased expression of MIR145 mRNA CTD PMID:25933445 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965 		JBrowse link
G Mir146 microRNA 146 affects expression ISO Bleomycin affects the expression of MIR146A mRNA CTD PMID:25933445 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir146b microRNA 146b increases expression ISO Bleomycin results in increased expression of MIR146B mRNA CTD PMID:25933445 NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309 		JBrowse link
G Mir148b microRNA 148b decreases expression ISO Bleomycin results in decreased expression of MIR148B mRNA CTD PMID:25933445 NCBI chr15:103,193,552...103,193,648
Ensembl chr15:103,193,552...103,193,648 		JBrowse link
G Mir150 microRNA 150 affects expression ISO Bleomycin affects the expression of MIR150 mRNA CTD PMID:25933445 NCBI chr 7:44,771,181...44,771,245
Ensembl chr 7:44,771,181...44,771,245 		JBrowse link
G Mir151 microRNA 151 decreases expression ISO Bleomycin results in decreased expression of MIR151 mRNA CTD PMID:25933445 NCBI chr15:73,126,664...73,126,731
Ensembl chr15:73,126,664...73,126,731 		JBrowse link
G Mir152 microRNA 152 decreases expression ISO Bleomycin results in decreased expression of MIR152 mRNA CTD PMID:25933445 NCBI chr11:96,741,219...96,741,291
Ensembl chr11:96,741,219...96,741,291 		JBrowse link
G Mir15b microRNA 15b affects expression ISO Bleomycin affects the expression of MIR15B mRNA CTD PMID:25933445 NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168 		JBrowse link
G Mir16-2 microRNA 16-2 decreases expression ISO Bleomycin results in decreased expression of MIR16 mRNA CTD PMID:25933445 NCBI chr 3:68,917,235...68,917,329
Ensembl chr 3:68,917,235...68,917,329 		JBrowse link
G Mir17 microRNA 17 affects expression ISO Bleomycin affects the expression of MIR17 mRNA CTD PMID:25933445 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186 		JBrowse link
G Mir18 microRNA 18 increases expression ISO Bleomycin results in increased expression of MIR18A mRNA CTD PMID:25933445 NCBI chr14:115,281,283...115,281,378
Ensembl chr14:115,281,283...115,281,378 		JBrowse link
G Mir181c microRNA 181c decreases expression ISO Bleomycin results in decreased expression of MIR181C mRNA CTD PMID:25933445 NCBI chr 8:84,905,502...84,905,590
Ensembl chr 8:84,905,502...84,905,590 		JBrowse link
G Mir181d microRNA 181d decreases expression ISO Bleomycin results in decreased expression of MIR181D mRNA CTD PMID:25933445 NCBI chr 8:84,905,345...84,905,416
Ensembl chr 8:84,905,345...84,905,416 		JBrowse link
G Mir183 microRNA 183 affects expression ISO Bleomycin affects the expression of MIR183 mRNA CTD PMID:25933445 NCBI chr 6:30,169,667...30,169,736
Ensembl chr 6:30,169,667...30,169,736 		JBrowse link
G Mir1839 microRNA 1839 affects expression ISO Bleomycin affects the expression of SCARNA15 mRNA CTD PMID:25933445 NCBI chr 7:81,179,664...81,179,736
Ensembl chr 7:81,179,664...81,179,736 		JBrowse link
G Mir185 microRNA 185 decreases expression ISO Bleomycin results in decreased expression of MIR185 mRNA CTD PMID:25933445 NCBI chr16:18,145,265...18,145,329
Ensembl chr16:18,145,265...18,145,329 		JBrowse link
G Mir186 microRNA 186 decreases expression ISO Bleomycin results in decreased expression of MIR186 mRNA CTD PMID:25933445 NCBI chr 3:157,249,916...157,249,986
Ensembl chr 3:157,249,916...157,249,986 		JBrowse link
G Mir188 microRNA 188 affects expression ISO Bleomycin affects the expression of MIR188 mRNA CTD PMID:25933445 NCBI chr  X:7,114,228...7,114,295
Ensembl chr  X:7,114,228...7,114,295 		JBrowse link
G Mir195a microRNA 195a decreases expression ISO Bleomycin results in decreased expression of MIR195 mRNA CTD PMID:25933445 NCBI chr11:70,125,868...70,125,961
Ensembl chr11:70,125,868...70,125,961 		JBrowse link
G Mir199a-2 microRNA 199a-2 affects expression ISO Bleomycin affects the expression of MIR199A2 mRNA CTD PMID:25933445 NCBI chr 1:162,045,383...162,045,492
Ensembl chr 1:162,045,383...162,045,492 		JBrowse link
G Mir19a microRNA 19a affects expression ISO Bleomycin affects the expression of MIR19A mRNA CTD PMID:25933445 NCBI chr14:115,281,432...115,281,513
Ensembl chr14:115,281,432...115,281,513 		JBrowse link
G Mir200a microRNA 200a decreases expression ISO Bleomycin results in decreased expression of MIR200A mRNA CTD PMID:25933445 NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442 		JBrowse link
G Mir200b microRNA 200b decreases expression ISO Bleomycin results in decreased expression of MIR200B mRNA CTD PMID:25933445 NCBI chr 4:156,140,138...156,140,207
Ensembl chr 4:156,140,138...156,140,207 		JBrowse link
G Mir200c microRNA 200c decreases expression ISO Bleomycin results in decreased expression of MIR200C mRNA CTD PMID:25933445 NCBI chr 6:124,695,285...124,695,353
Ensembl chr 6:124,695,285...124,695,353 		JBrowse link
G Mir203 microRNA 203 decreases expression ISO Bleomycin results in decreased expression of MIR203 mRNA CTD PMID:25933445 NCBI chr12:112,097,314...112,097,389
Ensembl chr12:112,097,314...112,097,389 		JBrowse link
G Mir204 microRNA 204 decreases expression ISO Bleomycin results in decreased expression of MIR204 mRNA CTD PMID:25933445 NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036 		JBrowse link
G Mir20a microRNA 20a affects expression ISO Bleomycin affects the expression of MIR20A mRNA CTD PMID:25933445 NCBI chr14:115,281,589...115,281,695
Ensembl chr14:115,281,589...115,281,695 		JBrowse link
G Mir20b microRNA 20b affects expression ISO Bleomycin affects the expression of MIR20B mRNA CTD PMID:25933445 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069 		JBrowse link
G Mir210 microRNA 210 decreases expression ISO Bleomycin results in decreased expression of MIR210 mRNA CTD PMID:25933445 NCBI chr 7:140,801,297...140,801,406
Ensembl chr 7:140,801,297...140,801,406 		JBrowse link
G Mir211 microRNA 211 affects expression ISO Bleomycin affects the expression of MIR211 mRNA CTD PMID:25933445 NCBI chr 7:63,855,554...63,855,659
Ensembl chr 7:63,855,554...63,855,659 		JBrowse link
G Mir212 microRNA 212 affects expression ISO Bleomycin affects the expression of MIR212 mRNA CTD PMID:25933445 NCBI chr11:75,064,214...75,064,304
Ensembl chr11:75,064,214...75,064,304 		JBrowse link
G Mir214 microRNA 214 affects expression ISO Bleomycin affects the expression of MIR214 mRNA CTD PMID:25933445 NCBI chr 1:162,050,937...162,051,046
Ensembl chr 1:162,050,937...162,051,046 		JBrowse link
G Mir21a microRNA 21a increases expression ISO Bleomycin results in increased expression of MIR21 mRNA CTD PMID:25933445 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir22 microRNA 22 affects expression ISO Bleomycin affects the expression of MIR22 mRNA CTD PMID:25933445 NCBI chr11:75,354,542...75,354,636
Ensembl chr11:75,354,542...75,354,636 		JBrowse link
G Mir221 microRNA 221 decreases expression ISO Bleomycin results in decreased expression of MIR221 mRNA CTD PMID:25933445 NCBI chr  X:19,012,533...19,012,627
Ensembl chr  X:19,012,533...19,012,627 		JBrowse link
G Mir222 microRNA 222 decreases expression
affects expression		 ISO Bleomycin results in decreased expression of MIR222 mRNA
Bleomycin affects the expression of MIR222 mRNA		 CTD PMID:25933445 PMID:34425168 NCBI chr  X:19,013,132...19,013,210
Ensembl chr  X:19,013,132...19,013,210 		JBrowse link
G Mir223 microRNA 223 affects expression ISO Bleomycin affects the expression of MIR223 mRNA CTD PMID:25933445 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532 		JBrowse link
G Mir23a microRNA 23a decreases expression ISO Bleomycin results in decreased expression of MIR23A mRNA CTD PMID:25933445 NCBI chr 8:84,935,147...84,935,221
Ensembl chr 8:84,935,147...84,935,221 		JBrowse link
G Mir23b microRNA 23b decreases expression ISO Bleomycin results in decreased expression of MIR23B mRNA CTD PMID:25933445 NCBI chr13:63,448,298...63,448,371
Ensembl chr13:63,448,298...63,448,371 		JBrowse link
G Mir24-2 microRNA 24-2 decreases expression ISO Bleomycin results in decreased expression of MIR24-2 mRNA CTD PMID:25933445 NCBI chr 8:84,935,444...84,935,550
Ensembl chr 8:84,935,444...84,935,550 		JBrowse link
G Mir25 microRNA 25 affects expression ISO Bleomycin affects the expression of MIR25 mRNA CTD PMID:25933445 NCBI chr 5:138,163,583...138,163,666
Ensembl chr 5:138,163,583...138,163,666 		JBrowse link
G Mir26a-1 microRNA 26a-1 decreases expression ISO
EXP		 Bleomycin results in decreased expression of MIR26A mRNA
Bleomycin results in decreased expression of MIR26A-1		 CTD PMID:25933445 PMID:35785413 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953 		JBrowse link
G Mir26b microRNA 26b decreases expression ISO Bleomycin results in decreased expression of MIR26B mRNA CTD PMID:25933445 NCBI chr 1:74,433,469...74,433,553
Ensembl chr 1:74,433,469...74,433,553 		JBrowse link
G Mir27a microRNA 27a decreases expression ISO Bleomycin results in decreased expression of MIR27A mRNA CTD PMID:25933445 NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387 		JBrowse link
G Mir27b microRNA 27b decreases expression ISO Bleomycin results in decreased expression of MIR27B mRNA CTD PMID:25933445 NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598 		JBrowse link
G Mir28a microRNA 28a decreases expression ISO Bleomycin results in decreased expression of MIR28 mRNA CTD PMID:25933445 NCBI chr16:24,646,605...24,646,690
Ensembl chr16:24,646,605...24,646,690 		JBrowse link
G Mir296 microRNA 296 affects expression ISO Bleomycin affects the expression of MIR296 mRNA CTD PMID:25933445 NCBI chr 2:174,108,840...174,108,918
Ensembl chr 2:174,108,840...174,108,918 		JBrowse link
G Mir29a microRNA 29a decreases expression ISO Bleomycin results in decreased expression of MIR29A mRNA CTD PMID:25933445 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682 		JBrowse link
G Mir301 microRNA 301 affects expression ISO Bleomycin affects the expression of MIR301A mRNA CTD PMID:25933445 NCBI chr11:87,003,830...87,003,915
Ensembl chr11:87,003,830...87,003,915 		JBrowse link
G Mir3068 microRNA 3068 decreases expression ISO Bleomycin results in decreased expression of SNORA58 mRNA CTD PMID:25933445 NCBI chr12:87,484,449...87,484,527
Ensembl chr12:87,484,449...87,484,527
Ensembl chr12:87,484,449...87,484,527 		JBrowse link
G Mir30a microRNA 30a decreases expression ISO Bleomycin results in decreased expression of MIR30A mRNA CTD PMID:25933445 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420 		JBrowse link
G Mir30b microRNA 30b decreases expression ISO Bleomycin results in decreased expression of MIR30B mRNA CTD PMID:25933445 NCBI chr15:68,209,264...68,209,359
Ensembl chr15:68,209,264...68,209,359 		JBrowse link
G Mir30c-2 microRNA 30c-2 decreases expression ISO Bleomycin results in decreased expression of MIR30C2 mRNA CTD PMID:25933445 NCBI chr 1:23,330,782...23,330,865
Ensembl chr 1:23,330,782...23,330,865 		JBrowse link
G Mir30d microRNA 30d decreases expression ISO Bleomycin results in decreased expression of MIR30D mRNA CTD PMID:25933445 NCBI chr15:68,213,057...68,213,138
Ensembl chr15:68,213,057...68,213,138 		JBrowse link
G Mir30e microRNA 30e decreases expression ISO Bleomycin results in decreased expression of MIR30E mRNA CTD PMID:25933445 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894 		JBrowse link
G Mir31 microRNA 31 decreases expression ISO Bleomycin results in decreased expression of MIR31 mRNA CTD PMID:25933445 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899 		JBrowse link
G Mir32 microRNA 32 increases expression ISO Bleomycin results in increased expression of MIR32 mRNA CTD PMID:25933445 NCBI chr 4:56,895,229...56,895,298
Ensembl chr 4:56,895,229...56,895,298 		JBrowse link
G Mir320 microRNA 320 decreases expression ISO Bleomycin results in decreased expression of MIR320A mRNA CTD PMID:25933445 NCBI chr14:70,680,950...70,681,031
Ensembl chr14:70,680,950...70,681,031 		JBrowse link
G Mir322 microRNA 322 decreases expression ISO Bleomycin results in decreased expression of MIR322 mRNA CTD PMID:25933445 NCBI chr  X:52,143,132...52,143,226
Ensembl chr  X:52,143,132...52,143,226 		JBrowse link
G Mir324 microRNA 324 affects expression ISO Bleomycin affects the expression of MIR324 mRNA CTD PMID:25933445 NCBI chr11:69,902,869...69,902,957
Ensembl chr11:69,902,869...69,902,957 		JBrowse link
G Mir326 microRNA 326 decreases expression ISO Bleomycin results in decreased expression of MIR326 mRNA CTD PMID:25933445 NCBI chr 7:99,201,476...99,201,570
Ensembl chr 7:99,201,476...99,201,570 		JBrowse link
G Mir328 microRNA 328 affects expression ISO Bleomycin affects the expression of MIR328 mRNA CTD PMID:25933445 NCBI chr 8:106,034,996...106,035,092
Ensembl chr 8:106,034,996...106,035,092 		JBrowse link
G Mir33 microRNA 33 decreases expression ISO Bleomycin results in decreased expression of MIR33 mRNA CTD PMID:25933445 NCBI chr15:82,082,323...82,082,391
Ensembl chr15:82,082,323...82,082,391 		JBrowse link
G Mir330 microRNA 330 decreases expression ISO Bleomycin results in decreased expression of MIR330 mRNA CTD PMID:25933445 NCBI chr 7:18,915,390...18,915,487
Ensembl chr 7:18,915,390...18,915,487 		JBrowse link
G Mir331 microRNA 331 decreases expression ISO Bleomycin results in decreased expression of MIR331 mRNA CTD PMID:25933445 NCBI chr10:93,799,630...93,799,725
Ensembl chr10:93,799,630...93,799,725 		JBrowse link
G Mir340 microRNA 340 increases expression ISO Bleomycin results in increased expression of MIR340-1 mRNA CTD PMID:25933445 NCBI chr11:49,960,529...49,960,626
Ensembl chr11:49,960,529...49,960,626 		JBrowse link
G Mir342 microRNA 342 decreases expression ISO Bleomycin results in decreased expression of MIR342 mRNA CTD PMID:25933445 NCBI chr12:108,624,879...108,624,977
Ensembl chr12:108,624,879...108,624,977 		JBrowse link
G Mir345 microRNA 345 decreases expression ISO Bleomycin results in decreased expression of MIR345 mRNA CTD PMID:25933445 NCBI chr12:108,802,899...108,802,994
Ensembl chr12:108,802,899...108,802,994 		JBrowse link
G Mir34a microRNA 34a affects expression
decreases expression		 ISO Bleomycin affects the expression of MIR34A mRNA
Bleomycin results in decreased expression of MIR34A mRNA		 CTD PMID:25933445 PMID:34425168 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012 		JBrowse link
G Mir34b microRNA 34b decreases expression ISO Bleomycin results in decreased expression of MIR34B mRNA CTD PMID:25933445 NCBI chr 9:51,014,862...51,014,945
Ensembl chr 9:51,014,862...51,014,945 		JBrowse link
G Mir34c microRNA 34c decreases expression ISO Bleomycin results in decreased expression of MIR34C mRNA CTD PMID:25933445 NCBI chr 9:51,014,334...51,014,410
Ensembl chr 9:51,014,334...51,014,410 		JBrowse link
G Mir361 microRNA 361 decreases expression ISO Bleomycin results in decreased expression of MIR361 mRNA CTD PMID:25933445 NCBI chr  X:111,984,521...111,984,590
Ensembl chr  X:111,984,521...111,984,590 		JBrowse link
G Mir365-2 microRNA 365-2 decreases expression ISO Bleomycin results in decreased expression of MIR365B mRNA CTD PMID:25933445 NCBI chr11:79,617,226...79,617,337
Ensembl chr11:79,617,226...79,617,337 		JBrowse link
G Mir374c microRNA 374c decreases expression ISO Bleomycin results in decreased expression of MIR374B mRNA CTD PMID:25933445 NCBI chr  X:102,616,691...102,616,739
Ensembl chr  X:102,616,691...102,616,739 		JBrowse link
G Mir375 microRNA 375 decreases expression ISO Bleomycin results in decreased expression of MIR375 mRNA CTD PMID:25933445 NCBI chr 1:74,939,817...74,939,880
Ensembl chr 1:74,939,817...74,939,880 		JBrowse link
G Mir409 microRNA 409 affects expression ISO Bleomycin affects the expression of MIR409 mRNA CTD PMID:25933445 NCBI chr12:109,709,592...109,709,670
Ensembl chr12:109,709,592...109,709,670 		JBrowse link
G Mir423 microRNA 423 decreases expression ISO Bleomycin results in decreased expression of MIR423 mRNA CTD PMID:25933445 NCBI chr11:76,968,890...76,968,998
Ensembl chr11:76,968,890...76,968,998 		JBrowse link
G Mir425 microRNA 425 affects expression ISO Bleomycin affects the expression of MIR425 mRNA CTD PMID:25933445 NCBI chr 9:108,445,976...108,446,060
Ensembl chr 9:108,445,976...108,446,060 		JBrowse link
G Mir429 microRNA 429 decreases expression ISO Bleomycin results in decreased expression of MIR429 mRNA CTD PMID:25933445 NCBI chr 4:156,138,362...156,138,444
Ensembl chr 4:156,138,362...156,138,444 		JBrowse link
G Mir449a microRNA 449a affects expression ISO Bleomycin affects the expression of MIR449A mRNA CTD PMID:25933445 NCBI chr13:113,174,068...113,174,158
Ensembl chr13:113,174,068...113,174,158 		JBrowse link
G Mir450-1 microRNA 450-1 decreases expression ISO Bleomycin results in decreased expression of MIR450A1 mRNA CTD PMID:25933445 NCBI chr  X:52,137,031...52,137,121
Ensembl chr  X:52,137,031...52,137,121 		JBrowse link
G Mir451a microRNA 451a decreases expression ISO
EXP		 Bleomycin results in decreased expression of MIR451A mRNA
Bleomycin results in decreased expression of MIR451A protein		 CTD PMID:25933445 PMID:34460027 NCBI chr11:77,963,996...77,964,067
Ensembl chr11:77,963,996...77,964,067 		JBrowse link
G Mir494 microRNA 494 decreases expression ISO Bleomycin results in decreased expression of MIR494 mRNA CTD PMID:25933445 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Mir497 microRNA 497 decreases expression ISO Bleomycin results in decreased expression of MIR497 mRNA CTD PMID:25933445 NCBI chr11:70,125,543...70,125,626
Ensembl chr11:70,125,543...70,125,626 		JBrowse link
G Mir500 microRNA 500 affects expression ISO Bleomycin affects the expression of MIR500 mRNA CTD PMID:25933445 NCBI chr  X:7,103,922...7,104,013
Ensembl chr  X:7,103,922...7,104,013 		JBrowse link
G Mir503 microRNA 503 decreases expression ISO Bleomycin results in decreased expression of MIR503 mRNA CTD PMID:25933445 NCBI chr  X:52,142,861...52,142,931
Ensembl chr  X:52,142,861...52,142,931 		JBrowse link
G Mir532 microRNA 532 affects expression ISO Bleomycin affects the expression of MIR532 mRNA CTD PMID:25933445 NCBI chr  X:7,114,641...7,114,736
Ensembl chr  X:7,114,641...7,114,736 		JBrowse link
G Mir542 microRNA 542 decreases expression ISO Bleomycin results in decreased expression of MIR542 mRNA CTD PMID:25933445 NCBI chr  X:52,138,280...52,138,364
Ensembl chr  X:52,138,280...52,138,364 		JBrowse link
G Mir652 microRNA 652 affects expression ISO Bleomycin affects the expression of MIR652 mRNA CTD PMID:25933445 NCBI chr  X:141,521,996...141,522,093
Ensembl chr  X:141,521,996...141,522,093 		JBrowse link
G Mir93 microRNA 93 affects expression ISO Bleomycin affects the expression of MIR93 mRNA CTD PMID:25933445 NCBI chr 5:138,163,785...138,163,872
Ensembl chr 5:138,163,785...138,163,872 		JBrowse link
G Mir96 microRNA 96 affects expression ISO Bleomycin affects the expression of MIR96 mRNA CTD PMID:25933445 NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550 		JBrowse link
G Mir98 microRNA 98 decreases expression ISO Bleomycin results in decreased expression of MIR98 mRNA CTD PMID:25933445 NCBI chr  X:150,696,210...150,696,317
Ensembl chr  X:150,696,210...150,696,317 		JBrowse link
G Mir99a microRNA 99a decreases expression ISO Bleomycin results in decreased expression of MIR99A mRNA CTD PMID:25933445 NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888 		JBrowse link
G Mir99b microRNA 99b decreases expression ISO Bleomycin results in decreased expression of MIR99B mRNA CTD PMID:25933445 NCBI chr17:18,050,450...18,050,519
Ensembl chr17:18,050,450...18,050,519 		JBrowse link
G Mirlet7b microRNA let7b decreases expression ISO Bleomycin results in decreased expression of MIRLET7B mRNA CTD PMID:25933445 NCBI chr15:85,591,520...85,591,604
Ensembl chr15:85,591,520...85,591,604 		JBrowse link
G Mirlet7d microRNA let7d decreases expression ISO Bleomycin results in decreased expression of MIRLET7D mRNA CTD PMID:25933445 NCBI chr13:48,689,488...48,689,590
Ensembl chr13:48,689,488...48,689,590 		JBrowse link
G Mirlet7i microRNA let7i decreases expression ISO Bleomycin results in decreased expression of MIRLET7I mRNA CTD PMID:25933445 NCBI chr10:122,821,545...122,821,629
Ensembl chr10:122,821,545...122,821,629 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO
EXP		 allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]
Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein
Bleomycin results in increased expression of and results in increased secretion of MMP2 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP2 mRNA]		 CTD PMID:23656969 PMID:26345256 PMID:26768587 PMID:29175452 PMID:35716765 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression EXP Bleomycin results in increased expression of MMP23 mRNA CTD PMID:36087614 NCBI chr 4:155,735,111...155,738,982
Ensembl chr 4:155,735,112...155,737,841 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of MMP3 mRNA
[MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]		 CTD PMID:28434932 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of MMP7 protein
honokiol inhibits the reaction [Bleomycin results in increased expression of MMP7 protein]		 CTD PMID:32032644 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,586 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions		 ISO
EXP		 Bleomycin results in increased expression of MMP9 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]
Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Bleomycin results in increased expression of and results in increased secretion of MMP9 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]		 CTD PMID:23656969 PMID:26526764 PMID:26768587 PMID:28300665 PMID:28694203 More... NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression		 EXP
ISO		 Oils, Volatile inhibits the reaction [Bleomycin results in increased activity of MPO protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein]
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein]		 CTD PMID:16317386 PMID:17035056 PMID:17118201 PMID:26093215 PMID:28850077 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression EXP Bleomycin results in increased expression of MRC1 mRNA CTD PMID:29033951 NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868 		JBrowse link
G Msn moesin decreases expression ISO Bleomycin results in decreased expression of MSN protein CTD PMID:25933445 NCBI chr  X:95,139,651...95,212,159
Ensembl chr  X:95,139,648...95,212,158 		JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric increases expression
multiple interactions		 ISO Bleomycin results in increased expression of MUC5AC mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]		 CTD PMID:18684396 PMID:26093215 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968 		JBrowse link
G Mucl3 mucin like 3 increases expression EXP Bleomycin results in increased expression of MUCL3 mRNA CTD PMID:36087614 NCBI chr17:35,946,647...35,954,587
Ensembl chr17:35,946,644...35,954,587 		JBrowse link
G Mug2 murinoglobulin 2 increases expression ISO Bleomycin results in increased expression of PZP protein CTD PMID:25933445 NCBI chr 6:121,983,688...122,062,927
Ensembl chr 6:121,983,720...122,062,924 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Bleomycin results in decreased expression of MXI1 mRNA CTD PMID:33770205 NCBI chr19:53,298,509...53,361,724
Ensembl chr19:53,298,949...53,364,241 		JBrowse link
G Myc myelocytomatosis oncogene increases response to substance EXP MYC protein results in increased susceptibility to Bleomycin CTD PMID:10449034 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Myh11 myosin, heavy polypeptide 11, smooth muscle decreases expression ISO Bleomycin results in decreased expression of MYH11 protein CTD PMID:25933445 NCBI chr16:14,012,392...14,109,227
Ensembl chr16:14,012,399...14,109,236 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha decreases expression ISO Bleomycin results in decreased expression of MYH6 protein CTD PMID:25933445 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myl12b myosin, light chain 12B, regulatory increases expression ISO Bleomycin results in increased expression of MYL12B protein CTD PMID:25933445 NCBI chr17:71,280,958...71,297,511
Ensembl chr17:71,280,128...71,297,885 		JBrowse link
G Myl4 myosin, light polypeptide 4 decreases expression ISO Bleomycin results in decreased expression of MYL4 protein CTD PMID:25933445 NCBI chr11:104,427,604...104,478,041
Ensembl chr11:104,441,489...104,486,579 		JBrowse link
G Myl6 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle increases expression ISO Bleomycin results in increased expression of MYL6 protein CTD PMID:25933445 NCBI chr10:128,326,728...128,329,755
Ensembl chr10:128,326,729...128,330,014 		JBrowse link
G Myo1c myosin IC decreases expression ISO Bleomycin results in decreased expression of MYO1C protein CTD PMID:25933445 NCBI chr11:75,541,345...75,565,450
Ensembl chr11:75,541,330...75,564,736 		JBrowse link
G Myo1e myosin IE decreases expression ISO Bleomycin results in decreased expression of MYO1E mRNA CTD PMID:33770205 NCBI chr 9:70,114,632...70,307,349
Ensembl chr 9:70,114,632...70,307,048 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression EXP Bleomycin results in decreased expression of NAP1L1 protein CTD PMID:29733421 NCBI chr10:111,308,754...111,334,011
Ensembl chr10:111,309,084...111,334,011 		JBrowse link
G Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 multiple interactions
increases expression		 ISO
EXP		 MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] CTD PMID:28726637 NCBI chr 2:168,318,330...168,443,900
Ensembl chr 2:168,318,330...168,443,577 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
increases phosphorylation
decreases expression
multiple interactions
increases expression		 EXP
ISO		 Bleomycin affects the localization of NFE2L2 protein
Bleomycin results in increased phosphorylation of NFE2L2 protein
Bleomycin results in decreased expression of NFE2L2 protein
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin affects the localization of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of NFE2L2 protein]
Bleomycin results in increased expression of NFE2L2 protein
Bleomycin results in decreased expression of NFE2L2 mRNA; Bleomycin results in decreased expression of NFE2L2 protein
Berberine promotes the reaction [Bleomycin results in increased expression of NFE2L2 protein]; celastrol inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]		 CTD PMID:23523906 PMID:23570914 PMID:26093215 PMID:26768587 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 increases activity
increases expression
multiple interactions		 EXP
ISO		 Bleomycin results in increased activity of NFKB1 protein
Bleomycin results in increased expression of NFKB1 mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]
NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]		 CTD PMID:12003776 PMID:26093215 PMID:26526764 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression ISO Bleomycin results in increased expression of NHERF1 protein CTD PMID:25933445 NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007 		JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 decreases expression ISO Bleomycin results in decreased expression of NHERF2 protein CTD PMID:25933445 NCBI chr17:24,858,255...24,869,279
Ensembl chr17:24,858,260...24,869,301 		JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr16:56,977,028...56,987,695
Ensembl chr16:56,977,028...56,987,704 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 increases expression EXP Bleomycin results in increased expression of NLRP10 mRNA CTD PMID:36087614 NCBI chr 7:108,521,060...108,529,365
Ensembl chr 7:108,521,059...108,529,385 		JBrowse link
G Nmbr neuromedin B receptor decreases expression ISO Bleomycin results in decreased expression of NMBR mRNA CTD PMID:15808516 NCBI chr10:14,634,894...14,647,202
Ensembl chr10:14,581,335...14,646,594 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression ISO Bleomycin results in increased expression of NME2 protein CTD PMID:25933445 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression
multiple interactions
increases secretion		 EXP
ISO		 Bleomycin results in increased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; rosiglitazone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased expression of NOS2 mRNA; Bleomycin results in increased expression of NOS2 protein
Berberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of NOS2 protein]		 CTD PMID:15684285 PMID:17434272 PMID:19362168 PMID:23523906 PMID:26526764 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Notch4 notch 4 increases expression EXP Bleomycin results in increased expression of NOTCH4 mRNA CTD PMID:36087614 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression		 EXP geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA] CTD PMID:35187969 PMID:37307957 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Npm1 nucleophosmin 1 increases expression ISO Bleomycin results in increased expression of NPM1 protein CTD PMID:25933445 NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 decreases activity
multiple interactions		 ISO Bleomycin results in decreased activity of NQO1 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of NQO1 protein]		 CTD PMID:26768587 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Bleomycin results in decreased expression of NR3C1 mRNA CTD PMID:15808516 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression ISO Bleomycin results in decreased expression of NR3C2 mRNA CTD PMID:15808516 NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641 		JBrowse link
G Nucb2 nucleobindin 2 increases expression ISO Bleomycin results in increased expression of NUCB2 protein CTD PMID:25933445 NCBI chr 7:116,103,579...116,139,823
Ensembl chr 7:116,103,604...116,139,819 		JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 increases expression
affects response to substance
multiple interactions		 EXP Bleomycin results in increased expression of OGG1 protein
OGG1 protein affects the susceptibility to Bleomycin
OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of OGG1 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of OGG1 protein]		 CTD PMID:35654123 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 increases expression EXP Bleomycin results in increased expression of OSR1 protein CTD PMID:34460027 NCBI chr12:9,624,442...9,631,500
Ensembl chr12:9,620,116...9,631,500 		JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression ISO Bleomycin results in increased expression of OSTF1 protein CTD PMID:25933445 NCBI chr19:18,557,728...18,609,177
Ensembl chr19:18,493,501...18,609,187 		JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide increases expression ISO Bleomycin results in increased expression of P4HB protein CTD PMID:25933445 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 increases expression ISO Bleomycin results in increased expression of PABPC1 protein CTD PMID:25933445 NCBI chr15:36,595,902...36,609,825
Ensembl chr15:36,595,905...36,609,912 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases expression
increases cleavage
multiple interactions		 EXP
ISO		 Bleomycin results in increased expression of PARP1 protein
Bleomycin results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]		 CTD PMID:15371238 PMID:16317386 PMID:32278510 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr15:102,378,974...102,408,503
Ensembl chr15:102,378,974...102,408,496 		JBrowse link
G Pdia3 protein disulfide isomerase associated 3 multiple interactions ISO [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 (elfin) increases expression ISO Bleomycin results in increased expression of PDLIM1 protein CTD PMID:25933445 NCBI chr19:40,210,683...40,260,060
Ensembl chr19:40,209,617...40,260,286 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression ISO Bleomycin results in increased expression of PDLIM5 protein CTD PMID:25933445 NCBI chr 3:141,945,346...142,101,480
Ensembl chr 3:141,945,351...142,101,454 		JBrowse link
G Pdxk pyridoxal (pyridoxine, vitamin B6) kinase increases expression ISO Bleomycin results in increased expression of PDXK protein CTD PMID:25933445 NCBI chr10:78,272,581...78,300,782
Ensembl chr10:78,272,578...78,300,809 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of PECAM1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of PECAM1 protein]		 CTD PMID:30825431 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Plau plasminogen activator, urokinase increases expression
decreases expression
multiple interactions		 EXP Bleomycin results in increased expression of PLAU mRNA; Bleomycin results in increased expression of PLAU protein
Bleomycin results in decreased expression of PLAU mRNA; Bleomycin results in decreased expression of PLAU protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU protein]		 CTD PMID:25648892 PMID:35716765 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of PLAUR mRNA; Bleomycin results in decreased expression of PLAUR protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR protein]		 CTD PMID:35716765 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Pml promyelocytic leukemia multiple interactions
increases expression		 EXP arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] CTD PMID:24762191 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
G Pnp2 purine-nucleoside phosphorylase 2 decreases expression ISO Bleomycin results in decreased expression of PNP protein CTD PMID:25933445 NCBI chr14:51,193,598...51,202,206
Ensembl chr14:51,193,449...51,202,206 		JBrowse link
G Podxl podocalyxin-like decreases expression ISO Bleomycin results in decreased expression of PODXL protein CTD PMID:25933445 NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916 		JBrowse link
G Polb polymerase (DNA directed), beta decreases response to substance EXP POLB results in decreased susceptibility to Bleomycin CTD PMID:21251944 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases response to substance		 EXP PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]
PPARA protein results in decreased susceptibility to Bleomycin		 CTD PMID:16317386 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression
multiple interactions		 EXP
ISO		 Bleomycin results in decreased expression of PPARG mRNA; Bleomycin results in decreased expression of PPARG protein
lenabasum inhibits the reaction [Bleomycin results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA]
Berberine inhibits the reaction [Bleomycin binds to PPARG protein]		 CTD PMID:19147827 PMID:27153807 PMID:29408570 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppfia4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of PPFIA4 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA]		 CTD PMID:30825431 NCBI chr 1:134,224,521...134,272,493
Ensembl chr 1:134,224,521...134,260,666 		JBrowse link
G Ppia peptidylprolyl isomerase A increases expression ISO Bleomycin results in increased expression of PPIA protein CTD PMID:25933445 NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO Bleomycin results in decreased expression of PRDX2 protein CTD PMID:25933445 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463 		JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression ISO Bleomycin results in decreased expression of PRDX6 protein CTD PMID:25933445 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789 		JBrowse link
G Prelp proline arginine-rich end leucine-rich repeat decreases expression ISO Bleomycin results in decreased expression of PRELP protein CTD PMID:25933445 NCBI chr 1:133,838,042...133,857,820
Ensembl chr 1:133,838,042...133,849,152 		JBrowse link
G Prl2c2 prolactin family 2, subfamily c, member 2 multiple interactions
increases expression		 EXP Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of PRL2C2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PRL2C2 protein] CTD PMID:30825431 NCBI chr13:13,170,705...13,179,978
Ensembl chr13:13,170,710...13,179,968 		JBrowse link
G Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 7:140,462,307...140,478,555
Ensembl chr 7:140,461,881...140,478,556 		JBrowse link
G Psme1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) increases expression ISO Bleomycin results in increased expression of PSME1 protein CTD PMID:25933445 NCBI chr14:55,815,951...55,818,984
Ensembl chr14:55,815,580...55,818,986 		JBrowse link
G Psme2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) decreases expression ISO Bleomycin results in decreased expression of PSME2 protein CTD PMID:25933445 NCBI chr14:55,824,897...55,828,558
Ensembl chr14:55,824,898...55,828,570 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions
increases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA] CTD PMID:30825431 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression ISO Bleomycin results in increased expression of PTBP1 protein CTD PMID:25933445 NCBI chr10:79,690,502...79,700,269
Ensembl chr10:79,690,261...79,700,605 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
decreases expression		 EXP ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN protein]
Bleomycin results in decreased expression of PTEN mRNA; Bleomycin results in decreased expression of PTEN protein		 CTD PMID:29408570 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptgdr prostaglandin D receptor increases expression EXP Bleomycin results in increased expression of PTGDR mRNA CTD PMID:20719937 NCBI chr14:45,088,692...45,096,832
Ensembl chr14:45,088,692...45,096,832 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of PTGS2 mRNA; Bleomycin results in increased expression of PTGS2 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of PTGS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of PTGS2 mRNA]		 CTD PMID:26526764 PMID:27704718 PMID:32828905 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptms parathymosin increases expression ISO Bleomycin results in increased expression of PTMS protein CTD PMID:25933445 NCBI chr 6:124,890,638...124,894,909
Ensembl chr 6:124,890,644...124,897,066 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression ISO Bleomycin results in increased expression of RAB1B protein CTD PMID:25933445 NCBI chr19:5,149,235...5,157,024
Ensembl chr19:5,149,233...5,157,100 		JBrowse link
G Rac2 Rac family small GTPase 2 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of RAC2 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA]		 CTD PMID:30825431 NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of RAD51AP1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA]		 CTD PMID:30825431 NCBI chr 6:126,900,378...126,916,664
Ensembl chr 6:126,900,013...126,916,550 		JBrowse link
G Ralb v-ral simian leukemia viral oncogene B increases expression ISO Bleomycin results in increased expression of RALB protein CTD PMID:25933445 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524 		JBrowse link
G Rap1b RAS related protein 1b increases expression ISO Bleomycin results in increased expression of RAP1B protein CTD PMID:25933445 NCBI chr10:117,650,502...117,681,879
Ensembl chr10:117,649,776...117,681,940 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
increases expression
decreases expression		 EXP
ISO		 Calcitriol inhibits the reaction [Bleomycin results in increased expression of RELA protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of RELA mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of RELA protein modified form]; methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Berberine inhibits the reaction [Bleomycin affects the localization of and results in increased expression of RELA protein]; Bleomycin affects the localization of and results in increased expression of RELA protein; thymoquinone inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Bleomycin results in increased expression of RELA mRNA; Bleomycin results in increased expression of RELA protein; Bleomycin results in increased expression of RELA protein modified form
Bleomycin results in decreased expression of RELA mRNA		 CTD PMID:21575650 PMID:22982510 PMID:23523906 PMID:26520185 PMID:29720568 More... NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B decreases expression EXP Bleomycin results in decreased expression of RELB mRNA CTD PMID:29720568 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363 		JBrowse link
G Retnla resistin like alpha increases expression
multiple interactions		 EXP Bleomycin results in increased expression of RETNLA mRNA; Bleomycin results in increased expression of RETNLA protein
IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]		 CTD PMID:15322207 PMID:26526764 NCBI chr16:48,662,972...48,664,824
Ensembl chr16:48,662,914...48,664,824 		JBrowse link
G Robo1 roundabout guidance receptor 1 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of ROBO1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA]		 CTD PMID:30825431 NCBI chr16:71,824,406...72,844,379
Ensembl chr16:72,105,194...72,842,983 		JBrowse link
G Rpl12 ribosomal protein L12 increases expression ISO Bleomycin results in increased expression of RPL12 protein CTD PMID:25933445 NCBI chr 2:32,851,724...32,854,057
Ensembl chr 2:32,851,571...32,855,357 		JBrowse link
G Rpl13 ribosomal protein L13 increases expression ISO Bleomycin results in increased expression of RPL13 protein CTD PMID:25933445 NCBI chr 8:123,829,089...123,831,983
Ensembl chr 8:123,829,089...123,831,983 		JBrowse link
G Rpl4 ribosomal protein L4 increases expression ISO Bleomycin results in increased expression of RPL4 protein CTD PMID:25933445 NCBI chr 9:64,080,159...64,085,805
Ensembl chr 9:64,080,657...64,085,948 		JBrowse link
G Rpl5 ribosomal protein L5 increases expression ISO Bleomycin results in increased expression of RPL5 protein CTD PMID:25933445 NCBI chr 5:108,048,388...108,056,871
Ensembl chr 5:108,048,368...108,056,871 		JBrowse link
G Rpl6 ribosomal protein L6 affects expression ISO Bleomycin affects the expression of RPL6 protein CTD PMID:25933445 NCBI chr 5:121,342,564...121,347,304
Ensembl chr 5:121,342,544...121,347,304 		JBrowse link
G Rps3a1 ribosomal protein S3A1 increases expression ISO Bleomycin results in increased expression of RPS3A1 protein CTD PMID:25933445 NCBI chr 3:86,045,247...86,049,975
Ensembl chr 3:86,045,247...86,050,009 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO Bleomycin results in increased expression of S100A11 protein CTD PMID:25933445 NCBI chr 3:93,427,803...93,433,595
Ensembl chr 3:93,427,795...93,433,594 		JBrowse link
G S100a4 S100 calcium binding protein A4 increases expression
multiple interactions		 ISO Bleomycin results in increased expression of S100A4 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of S100A4 protein]		 CTD PMID:25933445 PMID:31706003 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352 		JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) affects expression ISO Bleomycin affects the expression of S100A6 protein CTD PMID:25933445 NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488 		JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) increases expression ISO Bleomycin results in increased expression of S100A8 protein CTD PMID:25933445 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions EXP [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein CTD PMID:29033951 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions
increases expression		 EXP S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA] CTD PMID:29033951 NCBI chr13:51,562,654...51,576,833
Ensembl chr13:51,562,675...51,576,833 		JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 affects response to substance
multiple interactions		 EXP S1PR5 protein affects the susceptibility to Bleomycin
[S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein; [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA]		 CTD PMID:29033951 NCBI chr 9:21,154,213...21,159,739
Ensembl chr 9:21,154,208...21,159,739 		JBrowse link
G Scgb1a1 secretoglobin, family 1A, member 1 decreases expression ISO Bleomycin results in decreased expression of SCGB1A1 protein CTD PMID:25933445 NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322 		JBrowse link
G Scp2 sterol carrier protein 2, liver increases expression ISO Bleomycin results in increased expression of SCP2 protein CTD PMID:25933445 NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195 		JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression ISO Bleomycin results in increased expression of SCPEP1 protein CTD PMID:25933445 NCBI chr11:88,814,846...88,846,268
Ensembl chr11:88,814,846...88,846,291 		JBrowse link
G Scube3 signal peptide, CUB domain, EGF-like 3 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of SCUBE3 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA]		 CTD PMID:30825431 NCBI chr17:28,361,074...28,393,825
Ensembl chr17:28,361,115...28,393,828 		JBrowse link
G Sec14l3 SEC14-like lipid binding 3 decreases expression ISO Bleomycin results in decreased expression of SEC14L3 protein CTD PMID:25933445 NCBI chr11:4,014,853...4,028,990
Ensembl chr11:4,014,841...4,027,736 		JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression ISO Bleomycin results in decreased expression of SELENBP1 protein CTD PMID:25933445 NCBI chr 3:94,840,394...94,852,069
Ensembl chr 3:94,840,367...94,852,069 		JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of SERPINB2 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA]		 CTD PMID:30825431 NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases expression
multiple interactions
decreases expression		 EXP Bleomycin results in increased expression of SERPINE1 mRNA; Bleomycin results in increased expression of SERPINE1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 protein]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein]		 CTD PMID:29175452 PMID:30825431 PMID:35716765 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 multiple interactions
increases expression		 ISO allyl sulfide inhibits the reaction [Bleomycin results in increased expression of SERPINH1 protein] CTD PMID:23656969 PMID:25933445 NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression EXP Bleomycin results in increased expression of SFRP1 mRNA CTD PMID:26345256 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648 		JBrowse link
G Sftpa1 surfactant associated protein A1 multiple interactions
decreases expression
increases expression		 ISO [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]
Bleomycin results in decreased expression of SFTPA1 mRNA
Bleomycin results in increased expression of SFTPA1 protein		 CTD PMID:14617519 PMID:15782499 PMID:25933445 NCBI chr14:40,853,745...40,858,330
Ensembl chr14:40,853,739...40,858,409 		JBrowse link
G Sftpb surfactant associated protein B decreases expression
multiple interactions		 ISO
EXP		 Bleomycin results in decreased expression of SFTPB mRNA
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein		 CTD PMID:15782499 PMID:33647319 NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354 		JBrowse link
G Sftpc surfactant associated protein C decreases expression ISO Bleomycin results in decreased expression of SFTPC mRNA; Bleomycin results in decreased expression of SFTPC protein CTD PMID:34425168 NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521 		JBrowse link
G Sftpd surfactant associated protein D increases expression
multiple interactions
increases metabolic processing		 ISO
EXP		 Bleomycin results in increased expression of SFTPD mRNA; Bleomycin results in increased expression of SFTPD protein
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Bleomycin promotes the reaction [SFTPD protein binds to SFTPD protein binds to SFTPD protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased metabolism of SFTPD protein]		 CTD PMID:11880309 PMID:25933445 PMID:26526764 PMID:33647319 NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of SIRT1 mRNA; Bleomycin results in decreased expression of SIRT1 protein
resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 protein]		 CTD PMID:25707573 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc12a1 solute carrier family 12, member 1 increases expression ISO Bleomycin results in increased expression of SLC12A1 mRNA CTD PMID:15808516 NCBI chr 2:124,994,430...125,071,922
Ensembl chr 2:124,994,425...125,071,922 		JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 increases expression ISO Bleomycin results in increased expression of SLC1A2 mRNA CTD PMID:15808516 NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129 		JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 decreases expression ISO Bleomycin results in decreased expression of SLC25A4 protein CTD PMID:25933445 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321 		JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 decreases expression ISO Bleomycin results in decreased expression of SLC25A5 protein CTD PMID:25933445 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460 		JBrowse link
G Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 increases expression ISO Bleomycin results in increased expression of SLC6A12 mRNA CTD PMID:15808516 NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734 		JBrowse link
G Slc6a15 solute carrier family 6 (neurotransmitter transporter), member 15 multiple interactions
decreases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA] CTD PMID:30825431 NCBI chr10:103,203,320...103,255,240
Ensembl chr10:103,203,644...103,255,238 		JBrowse link
G Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of SLC7A1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA]		 CTD PMID:30825431 NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714 		JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 increases response to substance
multiple interactions		 EXP SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin
[SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]		 CTD PMID:32828905 NCBI chr 9:102,885,686...102,973,201
Ensembl chr 9:102,865,911...102,973,201 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression
multiple interactions		 EXP Bleomycin results in increased expression of SLPI mRNA; Bleomycin results in increased expression of SLPI protein
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA]		 CTD PMID:26345256 PMID:30825431 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation
increases expression		 EXP
ISO		 camostat inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]
Bleomycin results in increased expression of SMAD2 mRNA
yupingfeng inhibits the reaction [Bleomycin results in increased expression of SMAD2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]		 CTD PMID:26599507 PMID:32032644 PMID:35187969 PMID:37898439 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA]
Bleomycin results in increased phosphorylation of SMAD3 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]		 CTD PMID:26093215 PMID:27704718 PMID:32032644 PMID:35187969 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Smad7 SMAD family member 7 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Bleomycin results in decreased expression of SMAD7 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA]		 CTD PMID:26093215 PMID:29033951 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A increases phosphorylation ISO Bleomycin results in increased phosphorylation of SMC1A protein CTD PMID:24933654 NCBI chr  X:150,799,386...150,844,969
Ensembl chr  X:150,799,424...150,845,690 		JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO Bleomycin results in decreased expression of SMIM14 mRNA CTD PMID:33770205 NCBI chr 5:65,604,187...65,694,492
Ensembl chr 5:65,604,187...65,694,527 		JBrowse link
G Smtn smoothelin decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of SMTN mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA]		 CTD PMID:30825431 NCBI chr11:3,467,522...3,489,337
Ensembl chr11:3,467,523...3,490,612 		JBrowse link
G Snhg6 small nucleolar RNA host gene 6 increases expression EXP Bleomycin results in increased expression of SNHG6 CTD PMID:35785413 NCBI chr 1:10,012,250...10,014,343
Ensembl chr 1:9,926,809...10,014,398 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Bleomycin results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression
multiple interactions
decreases expression
decreases activity		 ISO Bleomycin results in increased expression of SOD1 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]
Bleomycin results in decreased expression of SOD1 protein
Bleomycin results in decreased activity of SOD1 protein		 CTD PMID:8317554 PMID:25933445 PMID:30106319 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
multiple interactions
decreases activity		 ISO Bleomycin results in increased expression of SOD2 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in decreased activity of SOD2 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of SOD2 protein]		 CTD PMID:8317554 PMID:26768587 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein increases response to substance EXP SPARC protein results in increased susceptibility to Bleomycin CTD PMID:19446018 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009 		JBrowse link
G Sparcl1 SPARC-like 1 decreases expression ISO Bleomycin results in decreased expression of SPARCL1 protein CTD PMID:25933445 NCBI chr 5:104,226,974...104,261,954
Ensembl chr 5:104,226,977...104,261,599 		JBrowse link
G Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) increases expression EXP Bleomycin results in increased expression of SPC25 mRNA CTD PMID:36087614 NCBI chr 2:69,009,753...69,036,583
Ensembl chr 2:69,024,239...69,036,538 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP Bleomycin results in increased expression of SPP1 mRNA; Bleomycin results in increased expression of SPP1 protein CTD PMID:26345256 PMID:29175452 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 decreases expression ISO Bleomycin results in decreased expression of SPTAN1 protein CTD PMID:25933445 NCBI chr 2:29,855,572...29,921,463
Ensembl chr 2:29,855,572...29,921,463 		JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression EXP Bleomycin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296 		JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression ISO Bleomycin results in decreased expression of SSTR1 mRNA CTD PMID:15808516 NCBI chr12:58,258,524...58,262,822
Ensembl chr12:58,258,558...58,260,673 		JBrowse link
G Sstr2 somatostatin receptor 2 decreases expression ISO Bleomycin results in decreased expression of SSTR2 mRNA CTD PMID:15808516 NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854 		JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression ISO Bleomycin results in decreased expression of SSTR3 mRNA CTD PMID:15808516 NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) multiple interactions EXP Bleomycin results in increased expression of and results in increased activity of ST14 protein CTD PMID:26599507 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression ISO Bleomycin results in decreased expression of ST3GAL5 mRNA CTD PMID:33770205 NCBI chr 6:72,074,555...72,131,555
Ensembl chr 6:72,074,576...72,131,555 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases expression		 EXP honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
decreases response to substance		 EXP STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
STAT6 gene mutant form results in decreased susceptibility to Bleomycin		 CTD PMID:15322207 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions
increases expression		 EXP Soot inhibits the reaction [Bleomycin results in increased expression of STK11 protein] CTD PMID:31302203 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Stmn1 stathmin 1 increases expression ISO Bleomycin results in increased expression of STMN1 protein CTD PMID:25933445 NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154 		JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b increases expression ISO Bleomycin results in increased expression of SV2B mRNA CTD PMID:15808516 NCBI chr 7:74,764,642...74,959,143
Ensembl chr 7:74,764,642...74,959,010 		JBrowse link
G Tacr2 tachykinin receptor 2 decreases expression ISO Bleomycin results in decreased expression of TACR2 mRNA CTD PMID:15808516 NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769 		JBrowse link
G Tagln transgelin increases expression ISO Bleomycin results in increased expression of TAGLN protein CTD PMID:25933445 NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356 		JBrowse link
G Tagln2 transgelin 2 increases expression ISO Bleomycin results in increased expression of TAGLN2 protein CTD PMID:25933445 NCBI chr 1:172,327,813...172,334,942
Ensembl chr 1:172,327,614...172,334,947 		JBrowse link
G Taldo1 transaldolase 1 decreases expression ISO Bleomycin results in decreased expression of TALDO1 protein CTD PMID:25933445 NCBI chr 7:140,972,073...140,982,889
Ensembl chr 7:140,972,112...140,982,881 		JBrowse link
G Tbx21 T-box 21 increases expression EXP Bleomycin results in increased expression of TBX21 mRNA CTD PMID:29033951 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Tcp1 t-complex protein 1 multiple interactions EXP [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr17:13,135,216...13,143,954
Ensembl chr17:13,134,588...13,143,954 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B decreases expression ISO Bleomycin results in decreased expression of TENT4B mRNA CTD PMID:33770205 NCBI chr 8:88,925,229...88,989,942
Ensembl chr 8:88,925,841...88,986,350 		JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance EXP TERT gene mutant form results in decreased susceptibility to Bleomycin CTD PMID:18008008 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases secretion
increases expression		 EXP
ISO		 (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of TGFB1 mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of TGFB1 mRNA; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; camostat inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
andrographolide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Berberine inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
Bleomycin results in increased secretion of TGFB1 protein
Bleomycin results in increased expression of TGFB1 mRNA; Bleomycin results in increased expression of TGFB1 protein
yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]		 CTD PMID:14609568 PMID:15541506 PMID:16115399 PMID:16314464 PMID:17035056 More... NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression ISO Bleomycin results in decreased expression of TGFB1I1 protein CTD PMID:25933445 NCBI chr 7:127,845,963...127,852,884
Ensembl chr 7:127,845,984...127,854,871 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions EXP [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA] CTD PMID:28434932 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
increases expression		 EXP CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I multiple interactions
increases expression		 EXP
ISO		 [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]		 CTD PMID:28434932 PMID:28726637 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II multiple interactions EXP [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA] CTD PMID:28434932 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 increases expression EXP Bleomycin results in increased expression of TGIF2 mRNA CTD PMID:36087614 NCBI chr 2:156,681,737...156,697,490
Ensembl chr 2:156,681,927...156,697,490 		JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Bleomycin results in increased expression of THBS1 mRNA CTD PMID:29720568 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Thbs2 thrombospondin 2 multiple interactions
increases expression		 EXP Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of THBS2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of THBS2 protein] CTD PMID:30825431 NCBI chr17:14,885,762...14,914,524
Ensembl chr17:14,885,762...14,914,497 		JBrowse link
G Thop1 thimet oligopeptidase 1 decreases expression EXP Bleomycin results in decreased expression of THOP1 protein CTD PMID:29733421 NCBI chr10:80,905,917...80,918,194
Ensembl chr10:80,905,869...80,918,393 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression ISO Bleomycin results in decreased expression of THRB mRNA CTD PMID:15808516 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression
multiple interactions		 EXP Bleomycin results in increased expression of TIMP1 mRNA; Bleomycin results in increased expression of TIMP1 protein
Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]		 CTD PMID:26345256 PMID:28300665 PMID:32032644 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Tlr1 toll-like receptor 1 decreases expression EXP Bleomycin results in decreased expression of TLR1 mRNA CTD PMID:29720568 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906 		JBrowse link
G Tmcc3 transmembrane and coiled coil domains 3 decreases expression ISO Bleomycin results in decreased expression of TMCC3 mRNA CTD PMID:33770205 NCBI chr10:94,147,544...94,426,816
Ensembl chr10:94,147,811...94,426,818 		JBrowse link
G Tmem250 transmembrane protein 250 increases expression ISO Bleomycin results in increased expression of TMEM250 mRNA CTD PMID:33770205 NCBI chr 2:26,026,819...26,030,518
Ensembl chr 2:26,026,826...26,030,533 		JBrowse link
G Tmem87a transmembrane protein 87A increases expression ISO Bleomycin results in increased expression of TMEM87A mRNA CTD PMID:33770205 NCBI chr 2:120,185,790...120,234,597
Ensembl chr 2:120,185,793...120,234,594 		JBrowse link
G Tnc tenascin C increases expression
multiple interactions		 EXP Bleomycin results in increased expression of TNC mRNA; Bleomycin results in increased expression of TNC protein
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TNC protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TNC protein]		 CTD PMID:26345256 PMID:30825431 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
affects response to substance		 ISO
EXP		 [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]; Ozone inhibits the reaction [[Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TNF protein]; [SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of TNF protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of TNF protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of TNF protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of TNF protein]
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of TNF protein; Berberine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of TNF protein]
Bleomycin results in increased expression of TNF mRNA; Bleomycin results in increased expression of TNF protein		 CTD PMID:8317554 PMID:8473757 PMID:11350791 PMID:12003776 PMID:14609568 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases response to substance
increases expression		 EXP TNFRSF1A results in increased susceptibility to Bleomycin
Bleomycin results in increased expression of TNFRSF1A mRNA		 CTD PMID:12003776 PMID:36087614 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b increases expression
increases response to substance		 ISO
EXP		 Bleomycin results in increased expression of TNFRSF1B protein
TNFRSF1B results in increased susceptibility to Bleomycin		 CTD PMID:12003776 PMID:15371238 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 decreases expression EXP Bleomycin results in decreased expression of TNFSF11 mRNA CTD PMID:29720568 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483 		JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 increases expression EXP Bleomycin results in increased expression of TNFSF4 mRNA CTD PMID:36087614 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981 		JBrowse link
G Tpm1 tropomyosin 1, alpha increases expression ISO Bleomycin results in increased expression of TPM1 protein CTD PMID:25933445 NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688 		JBrowse link
G Tpm3 tropomyosin 3, gamma increases expression ISO Bleomycin results in increased expression of TPM3 protein CTD PMID:25933445 NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209 		JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO Bleomycin results in increased expression of TPM4 protein CTD PMID:25933445 NCBI chr 8:72,889,132...72,906,986
Ensembl chr 8:72,884,018...72,906,986 		JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 decreases expression ISO Bleomycin results in decreased expression of TPPP3 protein CTD PMID:25933445 NCBI chr 8:106,194,124...106,198,189
Ensembl chr 8:106,194,125...106,198,158 		JBrowse link
G Traf2 TNF receptor-associated factor 2 decreases expression
increases expression		 ISO
EXP		 Bleomycin results in decreased expression of TRAF2 protein
Bleomycin results in increased expression of TRAF2 mRNA		 CTD PMID:15371238 PMID:36087614 NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 multiple interactions EXP Calcitriol inhibits the reaction [Bleomycin results in increased phosphorylation of ACT1 protein] CTD PMID:26520185 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303 		JBrowse link
G Trf transferrin increases expression ISO Bleomycin results in increased expression of TF protein CTD PMID:25933445 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643 		JBrowse link
G Trim28 tripartite motif-containing 28 increases phosphorylation ISO Bleomycin results in increased phosphorylation of TRIM28 protein CTD PMID:24933654 NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962 		JBrowse link
G Trp53 transformation related protein 53 increases expression
increases response to substance
increases phosphorylation
multiple interactions		 EXP
ISO		 Bleomycin results in increased expression of TRP53 protein
TP53 protein results in increased susceptibility to Bleomycin
Bleomycin results in increased phosphorylation of TP53 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]		 CTD PMID:9683175 PMID:20135637 PMID:24933654 PMID:26800624 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions EXP TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein] CTD PMID:26600069 NCBI chr10:77,743,556...77,805,746
Ensembl chr10:77,743,556...77,806,397 		JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression ISO Bleomycin results in decreased expression of TSHR mRNA CTD PMID:15808516 NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression ISO Bleomycin results in decreased expression of TUBA1C protein CTD PMID:25933445 NCBI chr15:98,927,772...98,935,986
Ensembl chr15:98,927,772...98,935,991 		JBrowse link
G Tubb2a tubulin, beta 2A class IIA decreases expression ISO Bleomycin results in decreased expression of TUBB2A protein
Bleomycin results in decreased expression of TUBB2A mRNA		 CTD PMID:25933445 PMID:33770205 NCBI chr13:34,258,261...34,261,991
Ensembl chr13:34,258,257...34,261,990 		JBrowse link
G Tubb4b tubulin, beta 4B class IVB decreases expression ISO Bleomycin results in decreased expression of TUBB4B protein CTD PMID:25933445 NCBI chr 2:25,112,170...25,114,714
Ensembl chr 2:25,112,172...25,114,714 		JBrowse link
G Twist1 twist basic helix-loop-helix transcription factor 1 increases expression EXP Bleomycin results in increased expression of TWIST1 protein CTD PMID:37126650 NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828 		JBrowse link
G Tymp thymidine phosphorylase increases expression
multiple interactions		 EXP Bleomycin results in increased expression of TYMP protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of TYMP protein]		 CTD PMID:30825431 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO Bleomycin results in decreased expression of UGCG mRNA CTD PMID:33770205 NCBI chr 4:59,189,452...59,222,833
Ensembl chr 4:59,189,257...59,222,833 		JBrowse link
G Ulk1 unc-51 like kinase 1 multiple interactions
increases expression		 EXP Soot inhibits the reaction [Bleomycin results in increased expression of ULK1 protein modified form] CTD PMID:31302203 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression ISO Bleomycin results in decreased expression of UQCRC1 protein CTD PMID:25933445 NCBI chr 9:108,765,716...108,778,709
Ensembl chr 9:108,765,701...108,778,691 		JBrowse link
G Vav1 vav 1 oncogene increases expression
multiple interactions		 EXP Bleomycin results in increased expression of VAV1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA]		 CTD PMID:30825431 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Vcl vinculin decreases expression ISO Bleomycin results in decreased expression of VCL protein CTD PMID:25933445 NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Bleomycin results in increased expression of VEGFA mRNA CTD PMID:26093215 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vegfb vascular endothelial growth factor B increases expression
multiple interactions		 EXP Bleomycin results in increased expression of VEGFB protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of VEGFB protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VEGFB protein]		 CTD PMID:30825431 NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019 		JBrowse link
G Vim vimentin increases expression
decreases expression
affects expression
multiple interactions		 ISO
EXP		 Bleomycin results in increased expression of VIM protein
Bleomycin results in decreased expression of VIM mRNA
Bleomycin affects the expression of VIM protein
Bleomycin results in increased expression of VIM mRNA; Bleomycin results in increased expression of VIM protein
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM protein]		 CTD PMID:25933445 PMID:34425168 PMID:35267148 PMID:35472619 PMID:37126650 More... NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Vwf Von Willebrand factor decreases expression
multiple interactions		 EXP Bleomycin results in decreased expression of VWF protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of VWF protein]		 CTD PMID:30825431 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
G Wif1 Wnt inhibitory factor 1 multiple interactions
decreases expression		 EXP Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA] CTD PMID:30825431 NCBI chr10:120,869,909...120,936,547
Ensembl chr10:120,869,865...120,936,555 		JBrowse link
G Wnt1 wingless-type MMTV integration site family, member 1 increases expression EXP Bleomycin results in increased expression of WNT1 mRNA CTD PMID:36087614 NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718 		JBrowse link
G Wnt10a wingless-type MMTV integration site family, member 10A increases expression EXP Bleomycin results in increased expression of WNT10A mRNA CTD PMID:36087614 NCBI chr 1:74,831,178...74,843,335
Ensembl chr 1:74,830,675...74,843,338 		JBrowse link
G Wnt9a wingless-type MMTV integration site family, member 9A increases expression EXP Bleomycin results in increased expression of WNT9A mRNA CTD PMID:36087614 NCBI chr11:59,197,675...59,224,378
Ensembl chr11:59,197,754...59,224,378 		JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 affects response to substance
decreases response to substance		 ISO XRCC1 gene polymorphism affects the susceptibility to Bleomycin
XRCC1 results in decreased susceptibility to Bleomycin		 CTD PMID:12082022 PMID:20705543 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Bleomycin CTD PMID:12384553 NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase decreases expression ISO Bleomycin results in decreased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 5:32,768,502...32,844,410
Ensembl chr 5:32,768,515...32,844,401 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide decreases expression ISO Bleomycin results in decreased expression of YWHAB protein CTD PMID:25933445 NCBI chr 2:163,837,082...163,860,508
Ensembl chr 2:163,836,880...163,860,508 		JBrowse link
G Zfx zinc finger protein X-linked increases expression ISO Bleomycin results in increased expression of ZFX mRNA CTD PMID:33770205 NCBI chr  X:93,118,237...93,194,250
Ensembl chr  X:93,118,237...93,167,308 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        antimicrobial agent 19546
          bleomycin 712
            bleomycin A2 633
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            heteroorganic entity 21482
                              organochalcogen compound 20966
                                organooxygen compound 20806
                                  carbon oxoacid 19593
                                    carboxylic acid 19589
                                      carboacyl group 18277
                                        univalent carboacyl group 18277
                                          carbamoyl group 18088
                                            carboxamide 18106
                                              peptide 11229
                                                peptide antibiotic 1838
                                                  chelate-forming peptide 711
                                                    bleomycin 712
                                                      bleomycin A2 633
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