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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:betamethasone valerate
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Accession:CHEBI:31277 term browser browse the term
Definition:A steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester.
Synonyms:exact_synonym: 9-fluoro-11beta,21-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl pentanoate
 related_synonym: 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17-valerate;   9-fluoro-11beta,21-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl valerate;   Betamethasone 17-valerate;   Formula=C27H37FO6;   InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1;   InChIKey=SNHRLVCMMWUAJD-SUYDQAKGSA-N;   SMILES=[H][C@@]12C[C@H](C)[C@](OC(=O)CCCC)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
 xref: Beilstein:4240001;   CAS:2152-44-5;   DrugBank:DB00443;   Drug_Central:354;   KEGG:D01357
 xref_mesh: MESH:D001624
 xref: Patent:NL6406615



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betamethasone valerate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule decreases expression ISO Betamethasone Valerate results in decreased expression of CD40 protein CTD PMID:15940147 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd83 CD83 molecule decreases expression ISO Betamethasone Valerate results in decreased expression of CD83 protein CTD PMID:15940147 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Betamethasone Valerate results in decreased expression of CD86 protein CTD PMID:15940147 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Csf2 colony stimulating factor 2 decreases expression ISO Betamethasone Valerate results in decreased expression of CSF2 protein CTD PMID:11407316 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ifng interferon gamma decreases expression ISO Betamethasone Valerate results in decreased expression of IFNG protein CTD PMID:11407316 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 decreases expression ISO Betamethasone Valerate results in decreased expression of IL2 protein CTD PMID:11407316 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il3 interleukin 3 decreases expression ISO Betamethasone Valerate results in decreased expression of IL3 protein CTD PMID:11407316 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 decreases expression ISO Betamethasone Valerate results in decreased expression of IL4 protein CTD PMID:11407316 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 decreases expression ISO Betamethasone Valerate results in decreased expression of IL5 protein CTD PMID:11407316 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      application 19622
        anti-asthmatic agent 9296
          betamethasone 25
            betamethasone valerate 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      ketone 17140
                                        oxyketone 8803
                                          alpha-oxyketone 8803
                                            alpha-hydroxy ketone 8803
                                              primary alpha-hydroxy ketone 7680
                                                betamethasone 25
                                                  betamethasone valerate 9
paths to the root