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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:betamethasone valerate
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Accession:CHEBI:31277 term browser browse the term
Definition:A steroid ester that is betamethasone in which the hydroxy group at the 17alpha position has been converted to the corresponding pentanoate ester.
Synonyms:exact_synonym: 9-fluoro-11beta,21-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl pentanoate
 related_synonym: 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17-valerate;   9-fluoro-11beta,21-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl valerate;   Betamethasone 17-valerate;   Formula=C27H37FO6;   InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1;   InChIKey=SNHRLVCMMWUAJD-SUYDQAKGSA-N;   SMILES=[H][C@@]12C[C@H](C)[C@](OC(=O)CCCC)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
 xref: Beilstein:4240001;   CAS:2152-44-5;   DrugBank:DB00443;   Drug_Central:354;   KEGG:D01357
 xref_mesh: MESH:D001624
 xref: Patent:NL6406615

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betamethasone valerate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule decreases expression ISO Betamethasone Valerate results in decreased expression of CD40 protein CTD PMID:15940147 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cd83 CD83 molecule decreases expression ISO Betamethasone Valerate results in decreased expression of CD83 protein CTD PMID:15940147 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790 		JBrowse link
G Cd86 CD86 molecule decreases expression ISO Betamethasone Valerate results in decreased expression of CD86 protein CTD PMID:15940147 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795 		JBrowse link
G Csf2 colony stimulating factor 2 decreases expression ISO Betamethasone Valerate results in decreased expression of CSF2 protein CTD PMID:11407316 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Ifng interferon gamma decreases expression ISO Betamethasone Valerate results in decreased expression of IFNG protein CTD PMID:11407316 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Il2 interleukin 2 decreases expression ISO Betamethasone Valerate results in decreased expression of IL2 protein CTD PMID:11407316 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il3 interleukin 3 decreases expression ISO Betamethasone Valerate results in decreased expression of IL3 protein CTD PMID:11407316 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il4 interleukin 4 decreases expression ISO Betamethasone Valerate results in decreased expression of IL4 protein CTD PMID:11407316 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531 		JBrowse link
G Il5 interleukin 5 decreases expression ISO Betamethasone Valerate results in decreased expression of IL5 protein CTD PMID:11407316 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      application 19477
        anti-asthmatic agent 9189
          betamethasone 24
            betamethasone valerate 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      ketone 16192
                                        oxyketone 8647
                                          alpha-oxyketone 8647
                                            alpha-hydroxy ketone 8647
                                              primary alpha-hydroxy ketone 7527
                                                betamethasone 24
                                                  betamethasone valerate 9
paths to the root