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ONTOLOGY REPORT - ANNOTATIONS


Term:betamethasone dipropionate
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Accession:CHEBI:31276 term browser browse the term
Definition:A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.
Synonyms:exact_synonym: 9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate
 related_synonym: 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate;   Betamethasone 17,21-dipropionate;   Formula=C28H37FO7;   InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1;   InChIKey=CIWBQSYVNNPZIQ-XYWKZLDCSA-N;   SMILES=[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
 xref: Beilstein:3638108;   CAS:5593-20-4;   DrugBank:DB00443;   Drug_Central:353;   KEGG:D01637
 xref_mesh: MESH:C011175
 xref: PMID:23621170;   PMID:24533503;   PMID:24593129;   PMID:24684739;   PMID:24684740;   PMID:24980277;   PMID:25279474;   PMID:25307472;   PMID:25355140;   PMID:25410121;   PMID:25412565;   PMID:25556056;   PMID:25566573;   PMID:25607705;   PMID:26094549;   PMID:26444907;   PMID:26659941;   Reaxys:3638108;   Wikipedia:Betamethasone_Dipropionate


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betamethasone dipropionate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        anti-asthmatic agent 9173
          betamethasone 24
            betamethasone dipropionate 1
              Enstilar 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      ketone 15948
                                        oxyketone 8487
                                          alpha-oxyketone 8487
                                            alpha-hydroxy ketone 8487
                                              primary alpha-hydroxy ketone 7450
                                                betamethasone 24
                                                  betamethasone dipropionate 1
                                                    Enstilar 0
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