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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benserazide hydrochloride
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Accession:CHEBI:31262 term browser browse the term
Definition:A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone.
Synonyms:exact_synonym: 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
 related_synonym: 2'-(2,3,4-trihydroxybenzyl)-DL-serinohydrazide monohydrochloride;   3-hydroxy-1-oxo-1-[2-(2,3,4-trihydroxybenzyl)hydrazinyl]propan-2-aminium chloride;   DL-serine 2-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride;   Formula=C10H16ClN3O5;   InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H;   InChIKey=ULFCBIUXQQYDEI-UHFFFAOYSA-N;   Ro 4-4602/001;   SMILES=Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O;   benserazide HCl
 xref: CAS:14919-77-8;   KEGG:D01653;   Reaxys:6494463



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  CHEBI ontology 19800
    role 19751
      biological role 19751
        pharmacological role 18837
          neurotransmitter agent 16451
            dopaminergic agent 5110
              benserazide hydrochloride 0
Path 2
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  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      halogen 18184
                        chlorine atom 18027
                          chlorine molecular entity 18027
                            elemental chlorine 8463
                              monoatomic chlorine 8447
                                chloride 8447
                                  chloride salt 8447
                                    organic chloride salt 918
                                      hydrochloride 686
                                        benserazide hydrochloride 0
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