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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Arkin (TN)
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Accession:CHEBI:31237 term browser browse the term
Synonyms:related_synonym: Formula=C22H25N3O4;   InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26);   InChIKey=ZVNYJIZDIRKMBF-UHFFFAOYSA-N;   OPC-8212;   SMILES=C(=O)(N1CCN(CC1)C=2C=C3C(=CC2)NC(CC3)=O)C4=CC(OC)=C(C=C4)OC;   Vesnarinone;   pieranometazine
 xref: CAS:81840-15-5;   Drug_Central:2817;   HMDB:HMDB0042059;   KEGG:D01690
 xref_mesh: MESH:C041667


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Arkin (TN) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO vesnarinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:9004165 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
affects response to substance
ISO vesnarinone results in decreased activity of KCNH2 protein
KCNH2 gene SNP affects the susceptibility to vesnarinone
CTD PMID:12695533, PMID:17146843 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO vesnarinone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:9004165 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Arkin (TN) 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Arkin (TN) 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.