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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Arkin (TN)
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Accession:CHEBI:31237 term browser browse the term
Synonyms:related_synonym: Formula=C22H25N3O4;   InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26);   InChIKey=ZVNYJIZDIRKMBF-UHFFFAOYSA-N;   OPC-8212;   SMILES=C(=O)(N1CCN(CC1)C=2C=C3C(=CC2)NC(CC3)=O)C4=CC(OC)=C(C=C4)OC;   Vesnarinone;   pieranometazine
 xref: CAS:81840-15-5;   Drug_Central:2817;   HMDB:HMDB0042059;   KEGG:D01690
 xref_mesh: MESH:C041667


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Arkin (TN) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO vesnarinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:9004165 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
affects response to substance		 ISO vesnarinone results in decreased activity of KCNH2 protein
KCNH2 gene SNP affects the susceptibility to vesnarinone		 CTD PMID:12695533 PMID:17146843 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO vesnarinone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:9004165 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      atom 19872
        nonmetal atom 19794
          carbon atom 19748
            organic molecular entity 19748
              Arkin (TN) 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            Arkin (TN) 3
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