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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Apafant
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Accession:CHEBI:31226 term browser browse the term
Synonyms:related_synonym: Formula=C22H22ClN5O2S
 xref: CAS:105219-56-5;   KEGG:D01652
 xref_mesh: MESH:C052518


show annotations for term's descendants           Sort by:
Apafant term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 WEB 2086 inhibits the reaction [IL1B protein results in increased expression of TNF protein]
WEB 2086 inhibits the reaction [Doxorubicin results in increased secretion of IL1B protein]		 CTD PMID:7575673 PMID:8132220 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Myb MYB proto-oncogene, transcription factor decreases expression ISO WEB 2086 results in decreased expression of MYB mRNA CTD PMID:11923217 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions EXP WEB 2086 binds to and results in decreased activity of PAFAH1B1 protein CTD PMID:12013527 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions ISO [WEB 2086 binds to and results in decreased activity of PTAFR protein] which results in decreased susceptibility to lipoxin A4; WEB 2086 binds to and results in decreased activity of PTAFR protein CTD PMID:7602232 PMID:8666909 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO WEB 2086 inhibits the reaction [IL1B protein results in increased expression of TNF protein] CTD PMID:7575673 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          carbon atom 19698
            organic molecular entity 19698
              Apafant 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            Apafant 5
paths to the root