Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antipyrine
go back to main search page
Accession:CHEBI:31225 term browser browse the term
Definition:A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Synonyms:related_synonym: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one;   2,3-Dimethyl-1-phenyl-5-pyrazolone;   Formula=C11H12N2O;   InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3;   InChIKey=VEQOALNAAJBPNY-UHFFFAOYSA-N;   SMILES=Cc1cc(=O)n(-c2ccccc2)n1C;   fenazona;   phenazone;   phenazonum
 xref: Beilstein:157775;   CAS:60-80-0;   DrugBank:DB01435;   Drug_Central:861;   HMDB:HMDB0015503;   KEGG:C13244;   KEGG:D01776;   LINCS:LSM-3038
 xref_mesh: MESH:D000983
 xref: PMID:24345239;   PMID:25038548;   PMID:25435228;   PMID:25631541;   PMID:26703262;   PMID:3425858;   Reaxys:157775;   Wikipedia:Antipyrine



show annotations for term's descendants           Sort by:
antipyrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgds prostaglandin D2 synthase decreases activity ISO Antipyrine results in decreased activity of PTGDS protein CTD PMID:15718289 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity ISO Antipyrine analog results in decreased activity of PTGS1 protein; Antipyrine results in decreased activity of PTGS1 protein CTD PMID:16141368 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO TNF protein affects the reaction [Endotoxins results in increased abundance of Antipyrine] CTD PMID:15659313 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        xenobiotic 18778
          antipyrine 3
            1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
            3-hydroxymethylantipyrine 0
            4-(5-carboxypentanamido)antipyrine 0
            4-(methylamino)antipyrine 0
            4-acetamidoantipyrine 0
            4-aminoantipyrine 0
            metamizole 0
            propyphenazone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  heteroarene 17172
                                    monocyclic heteroarene 14893
                                      azole 14396
                                        diazole 10488
                                          pyrazoles 2320
                                            pyrazolone 86
                                              antipyrine 3
                                                1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
                                                3-hydroxymethylantipyrine 0
                                                4-(5-carboxypentanamido)antipyrine 0
                                                4-(methylamino)antipyrine 0
                                                4-acetamidoantipyrine 0
                                                4-aminoantipyrine 0
                                                metamizole 0
                                                propyphenazone 0
paths to the root