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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antipyrine
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Accession:CHEBI:31225 term browser browse the term
Definition:A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at C-1 and C-5 and with a phenyl group at N-2.
Synonyms:related_synonym: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one;   2,3-Dimethyl-1-phenyl-5-pyrazolone;   Formula=C11H12N2O;   InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3;   InChIKey=VEQOALNAAJBPNY-UHFFFAOYSA-N;   SMILES=Cc1cc(=O)n(-c2ccccc2)n1C;   fenazona;   phenazone;   phenazonum
 xref: Beilstein:157775;   CAS:60-80-0;   DrugBank:DB01435;   Drug_Central:861;   HMDB:HMDB0015503;   KEGG:C13244;   KEGG:D01776;   LINCS:LSM-3038
 xref_mesh: MESH:D000983
 xref: PMID:24345239;   PMID:25038548;   PMID:25435228;   PMID:25631541;   PMID:26703262;   PMID:3425858;   Reaxys:157775;   Wikipedia:Antipyrine


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antipyrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgds prostaglandin D2 synthase decreases activity ISO Antipyrine results in decreased activity of PTGDS protein CTD PMID:15718289 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity ISO Antipyrine analog results in decreased activity of PTGS1 protein; Antipyrine results in decreased activity of PTGS1 protein CTD PMID:16141368 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO TNF protein affects the reaction [Endotoxins results in increased abundance of Antipyrine] CTD PMID:15659313 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    role 19732
      biological role 19732
        xenobiotic 18425
          antipyrine 3
            1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
            3-hydroxymethylantipyrine 0
            4-(5-carboxypentanamido)antipyrine 0
            4-(methylamino)antipyrine 0
            4-acetamidoantipyrine 0
            4-aminoantipyrine 0
            metamizole 0
            propyphenazone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19596
                        carbon atom 19586
                          organic molecular entity 19586
                            organic molecule 19519
                              organic cyclic compound 19349
                                organic heterocyclic compound 18574
                                  heteroarene 16526
                                    monocyclic heteroarene 13396
                                      azole 12575
                                        diazole 8253
                                          pyrazoles 1555
                                            pyrazolone 78
                                              antipyrine 3
                                                1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
                                                3-hydroxymethylantipyrine 0
                                                4-(5-carboxypentanamido)antipyrine 0
                                                4-(methylamino)antipyrine 0
                                                4-acetamidoantipyrine 0
                                                4-aminoantipyrine 0
                                                metamizole 0
                                                propyphenazone 0
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