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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antipyrine
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Accession:CHEBI:31225 term browser browse the term
Definition:A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Synonyms:related_synonym: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one;   2,3-Dimethyl-1-phenyl-5-pyrazolone;   Formula=C11H12N2O;   InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3;   InChIKey=VEQOALNAAJBPNY-UHFFFAOYSA-N;   SMILES=Cc1cc(=O)n(-c2ccccc2)n1C;   fenazona;   phenazone;   phenazonum
 xref: Beilstein:157775;   CAS:60-80-0;   DrugBank:DB01435;   Drug_Central:861;   HMDB:HMDB0015503;   KEGG:C13244;   KEGG:D01776;   LINCS:LSM-3038
 xref_mesh: MESH:D000983
 xref: PMID:24345239;   PMID:25038548;   PMID:25435228;   PMID:25631541;   PMID:26703262;   PMID:3425858;   Reaxys:157775;   Wikipedia:Antipyrine



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antipyrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgds prostaglandin D2 synthase decreases activity ISO Antipyrine results in decreased activity of PTGDS protein CTD PMID:15718289 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity ISO Antipyrine analog results in decreased activity of PTGS1 protein; Antipyrine results in decreased activity of PTGS1 protein CTD PMID:16141368 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO TNF protein affects the reaction [Endotoxins results in increased abundance of Antipyrine] CTD PMID:15659313 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20026
      biological role 20025
        xenobiotic 18703
          antipyrine 3
            1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
            3-hydroxymethylantipyrine 0
            4-(5-carboxypentanamido)antipyrine 0
            4-(methylamino)antipyrine 0
            4-acetamidoantipyrine 0
            4-aminoantipyrine 0
            metamizole 0
            propyphenazone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    p-block element atom 19974
                      carbon group element atom 19903
                        carbon atom 19896
                          organic molecular entity 19896
                            organic molecule 19844
                              organic cyclic compound 19605
                                organic heterocyclic compound 18890
                                  heteroarene 16627
                                    monocyclic heteroarene 13619
                                      azole 12850
                                        diazole 8636
                                          pyrazoles 2310
                                            pyrazolone 81
                                              antipyrine 3
                                                1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
                                                3-hydroxymethylantipyrine 0
                                                4-(5-carboxypentanamido)antipyrine 0
                                                4-(methylamino)antipyrine 0
                                                4-acetamidoantipyrine 0
                                                4-aminoantipyrine 0
                                                metamizole 0
                                                propyphenazone 0
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