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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antipyrine
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Accession:CHEBI:31225 term browser browse the term
Definition:A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Synonyms:related_synonym: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one;   2,3-Dimethyl-1-phenyl-5-pyrazolone;   Formula=C11H12N2O;   InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3;   InChIKey=VEQOALNAAJBPNY-UHFFFAOYSA-N;   SMILES=Cc1cc(=O)n(-c2ccccc2)n1C;   fenazona;   phenazone;   phenazonum
 xref: Beilstein:157775;   CAS:60-80-0;   DrugBank:DB01435;   Drug_Central:861;   HMDB:HMDB0015503;   KEGG:C13244;   KEGG:D01776;   LINCS:LSM-3038
 xref_mesh: MESH:D000983
 xref: PMID:24345239;   PMID:25038548;   PMID:25435228;   PMID:25631541;   PMID:26703262;   PMID:3425858;   Reaxys:157775;   Wikipedia:Antipyrine



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antipyrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgds prostaglandin D2 synthase decreases activity ISO Antipyrine results in decreased activity of PTGDS protein CTD PMID:15718289 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity ISO Antipyrine analog results in decreased activity of PTGS1 protein; Antipyrine results in decreased activity of PTGS1 protein CTD PMID:16141368 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO TNF protein affects the reaction [Endotoxins results in increased abundance of Antipyrine] CTD PMID:15659313 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    role 19824
      biological role 19822
        xenobiotic 18737
          antipyrine 3
            1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
            3-hydroxymethylantipyrine 0
            4-(5-carboxypentanamido)antipyrine 0
            4-(methylamino)antipyrine 0
            4-acetamidoantipyrine 0
            4-aminoantipyrine 0
            metamizole 0
            propyphenazone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    p-block element atom 19796
                      carbon group element atom 19741
                        carbon atom 19737
                          organic molecular entity 19737
                            organic molecule 19690
                              organic cyclic compound 19501
                                organic heterocyclic compound 18878
                                  heteroarene 17137
                                    monocyclic heteroarene 14871
                                      azole 14375
                                        diazole 10476
                                          pyrazoles 2320
                                            pyrazolone 87
                                              antipyrine 3
                                                1-(4-sulfophenyl)-3-carboxy-4-amino-5-oxopyrazole 0
                                                3-hydroxymethylantipyrine 0
                                                4-(5-carboxypentanamido)antipyrine 0
                                                4-(methylamino)antipyrine 0
                                                4-acetamidoantipyrine 0
                                                4-aminoantipyrine 0
                                                metamizole 0
                                                propyphenazone 0
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