Term: | alfacalcidol |
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Accession: | CHEBI:31186
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Definition: | A member of the class of D3 vitamins that is calciol in which the hydrogen at the 1alpha position is replaced by a hydroxy group. It is an active metabolite of cholecalciferol, which performs important functions in regulation of the calcium balance and the bone metabolism. |
Synonyms: | exact_synonym: | (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3-diol |
| related_synonym: | (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1alpha,3beta-diol; 1alpha-hydroxy-vitamin D3; 1alpha-hydroxycholecalciferol; 1alpha-hydroxyvitamin D3; 9,10-secocholesta-5,7,10(19)-triene-1alpha,3beta-diol; Alsiodol; Formula=C27H44O2; InChI=1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1; InChIKey=OFHCOWSQAMBJIW-AVJTYSNKSA-N; SMILES=CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CCC\\C2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C; alfacalcidolum |
| xref: | CAS:41294-56-8; DrugBank:DB01436; Drug_Central:130; HMDB:HMDB0015504; KEGG:D01518 |
| xref_mesh: | MESH:C008088 |
| xref: | PMID:17438884; PMID:17668216; PMID:20827552; PMID:22527138; PMID:22607568; PMID:24119718; PMID:24414552; Reaxys:2064794 |
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