CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2-methylserotonin
Accession: CHEBI:31085
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Definition: A tryptamine that has formula C11H14N2O.
Synonyms: exact_synonym: 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol
related_synonym: 2-Me 5-HT; 2-Methyl-5-hydroxytryptamine; 2-methyl-5-HT; Formula=C11H14N2O; InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3; InChIKey=WYWNEDARFVJQSG-UHFFFAOYSA-N; SMILES=Cc1[nH]c2ccc(O)cc2c1CCN
xref: Beilstein:7670; CAS:78263-90-8; KEGG:C13665
xref_mesh: MESH:C045918
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CXCL8
C-X-C motif chemokine ligand 8
multiple interactions
EXP
2-methyl-5-HT promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]
CTD
PMID:15802305
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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HTR3A
5-hydroxytryptamine receptor 3A
multiple interactions
EXP
2-methyl-5-HT binds to and results in increased activity of HTR3A protein
CTD
PMID:15802305
NCBI chr11:113,975,108...113,990,313
Ensembl chr11:113,975,075...113,990,313
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IL1B
interleukin 1 beta
multiple interactions
EXP
2-methyl-5-HT promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD
PMID:15802305
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL6
interleukin 6
multiple interactions
EXP
2-methyl-5-HT promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD
PMID:15802305
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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