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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
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Accession:CHEBI:31073 term browser browse the term
Definition:A sulfonic acid derivative that has formula C12H8N4O6S.
Synonyms:related_synonym: Formula=C12H8N4O6S;   InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22);   InChIKey=UQNAFPHGVPVTAL-UHFFFAOYSA-N;   NBQX;   SMILES=NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O
 xref: CAS:118876-58-7;   KEGG:C13667;   LINCS:LSM-3054
 xref_mesh: MESH:C062865


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2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adarb1 adenosine deaminase, RNA-specific, B1 multiple interactions EXP 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline promotes the reaction [perfluorooctane sulfonic acid results in increased expression of ADARB1 mRNA] CTD PMID:30508566 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
EXP 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Capsaicin results in increased expression of FOS]
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline results in decreased expression of FOS protein
CTD PMID:10401552, PMID:18539009 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of GRIA1 mRNA] CTD PMID:30508566 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Grip1 glutamate receptor interacting protein 1 multiple interactions EXP 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of GRIP1 mRNA] CTD PMID:30508566 NCBI chr 7:64,672,723...64,854,939
Ensembl chr 7:64,672,722...64,864,404
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK1 protein] CTD PMID:21278053 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Dizocilpine Maleate co-treated with 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline] inhibits the reaction [Dieldrin results in increased phosphorylation of MAPK3 protein] CTD PMID:21278053 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Plp1 proteolipid protein 1 decreases binding EXP NBQX decreases binding of Plp1 to Itgav protein in oligodendrocyte progenitor cells RGD PMID:16510724 RGD:30296668 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B multiple interactions EXP 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Estradiol results in increased expression of PPP1R9B protein] CTD PMID:17443789 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Wdr35 WD repeat domain 35 multiple interactions EXP 2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [domoic acid results in increased expression of WDR35 protein] CTD PMID:23289926 NCBI chr 6:34,094,291...34,152,048
Ensembl chr 6:34,094,306...34,151,622
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          sulfur atom 16292
            sulfur molecular entity 16292
              sulfur oxoacid derivative 12275
                sulfonic acid derivative 7340
                  2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                carbocyclic compound 18222
                                  carbopolycyclic compound 16971
                                    carbobicyclic compound 4561
                                      naphthalenes 3744
                                        2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline 9
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