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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:azetidine
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Accession:CHEBI:30968 term browser browse the term
Definition:An azacycloalkane that has formula C3H7N.
Synonyms:related_synonym: Formula=C3H7N;   InChI=1S/C3H7N/c1-2-4-3-1/h4H,1-3H2;   InChIKey=HONIICLYMWZJFZ-UHFFFAOYSA-N;   SMILES=C1CNC1;   azacyclobutane;   trimethylene imine;   trimethylenimine
 xref: Beilstein:102384;   CAS:503-29-7;   Gmelin:986
 xref_mesh: MESH:C082735


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azetidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CCL3 protein] CTD PMID:26522449 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ctsb cathepsin B multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of CTSB protein] CTD PMID:26522449 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CXCL2 protein] CTD PMID:26522449 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Il6 interleukin 6 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein] CTD PMID:26522449 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein] CTD PMID:26522449 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein] CTD PMID:26522449 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of MMP9 protein] CTD PMID:26522449 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate affects the localization of NFATC1 protein] CTD PMID:26522449 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein] CTD PMID:26522449 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO azetidine analog inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased expression of P2RX7 protein]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein] CTD PMID:26522449 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO azetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein] CTD PMID:26522449 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO azetidine analog inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased secretion of TNF protein]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased secretion of TNF protein] CTD PMID:26522449 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 affects localization ISO azetidine affects the localization of TRP53 protein CTD PMID:18813348 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
(S,S,S)-nicotianamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO nicotianamine results in decreased activity of ACE protein CTD PMID:26106051 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases activity ISO nicotianamine results in decreased activity of ACE2 protein CTD PMID:26106051 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
azetidinecarboxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cryab crystallin, alpha B increases expression ISO Azetidinecarboxylic Acid results in increased expression of CRYAB protein CTD PMID:8113214 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Azetidinecarboxylic Acid results in increased expression of HSPA1A mRNA CTD PMID:12085988 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Azetidinecarboxylic Acid results in increased expression of HSPA1B mRNA CTD PMID:12085988 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Azetidinecarboxylic Acid results in increased expression of HSPB1 protein CTD PMID:8113214 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
nicotianamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO nicotianamine results in decreased activity of ACE protein CTD PMID:26106051 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases activity ISO nicotianamine results in decreased activity of ACE2 protein CTD PMID:26106051 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19853
      atom 19851
        nonmetal atom 19733
          nitrogen atom 18620
            nitrogen molecular entity 18620
              organonitrogen compound 18395
                organonitrogen heterocyclic compound 17564
                  azacycloalkane 130
                    azetidine 19
                      azetidinecarboxylic acid + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic molecule 19568
                              organic cyclic compound 19378
                                organic heterocyclic compound 18495
                                  organic heteromonocyclic compound 16597
                                    saturated organic heteromonocyclic parent 5810
                                      azetidine 19
                                        azetidinecarboxylic acid + 6
paths to the root