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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-azaorotic acid
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Accession:CHEBI:30863 term browser browse the term
Definition:A 1,3,5-triazine that has formula C4H3N3O4.
Synonyms:related_synonym: 1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid;   Formula=C4H3N3O4;   InChI=1S/C4H3N3O4/c8-2(9)1-5-3(10)7-4(11)6-1/h(H,8,9)(H2,5,6,7,10,11);   InChIKey=RYYCJUAHISIHTL-UHFFFAOYSA-N;   SMILES=OC(=O)c1nc(=O)[nH]c(=O)[nH]1;   oxonic acid
 xref: Beilstein:383990;   CAS:937-13-3;   DrugBank:DB03209;   Drug_Central:2002
 xref_mesh: MESH:D010094

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5-azaorotic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 decreases expression EXP Oxonic Acid results in decreased expression of LGALS9 protein CTD PMID:19605544 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 multiple interactions
affects localization		 EXP Allopurinol inhibits the reaction [Oxonic Acid affects the localization of NFAT5 protein] CTD PMID:30651350 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression EXP Oxonic Acid results in decreased expression of SLC22A2 protein CTD PMID:19605544 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions EXP [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A6 protein CTD PMID:19605544 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A8 protein CTD PMID:19605544 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      chemical role 19345
        donor 18654
          Bronsted acid 18537
            oxoacid 18498
              carbon oxoacid 18378
                carboxylic acid 18373
                  monocarboxylic acid 17636
                    5-azaorotic acid 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        monocarboxylic acid 17636
                                          5-azaorotic acid 5
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