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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-azaorotic acid
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Accession:CHEBI:30863 term browser browse the term
Definition:A 1,3,5-triazine that has formula C4H3N3O4.
Synonyms:related_synonym: 1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid;   Formula=C4H3N3O4;   InChI=1S/C4H3N3O4/c8-2(9)1-5-3(10)7-4(11)6-1/h(H,8,9)(H2,5,6,7,10,11);   InChIKey=RYYCJUAHISIHTL-UHFFFAOYSA-N;   SMILES=OC(=O)c1nc(=O)[nH]c(=O)[nH]1;   oxonic acid
 xref: Beilstein:383990;   CAS:937-13-3;   DrugBank:DB03209;   Drug_Central:2002
 xref_mesh: MESH:D010094


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5-azaorotic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 decreases expression EXP Oxonic Acid results in decreased expression of LGALS9 protein CTD PMID:19605544 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 multiple interactions
affects localization
EXP Allopurinol inhibits the reaction [Oxonic Acid affects the localization of NFAT5 protein] CTD PMID:30651350 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression EXP Oxonic Acid results in decreased expression of SLC22A2 protein CTD PMID:19605544 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions EXP [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A6 protein CTD PMID:19605544 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP [Oxonic Acid co-treated with Uric Acid] results in decreased expression of SLC22A8 protein CTD PMID:19605544 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      chemical role 19250
        donor 18378
          Bronsted acid 18241
            oxoacid 18193
              carbon oxoacid 18073
                carboxylic acid 18061
                  monocarboxylic acid 17407
                    5-azaorotic acid 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          5-azaorotic acid 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.