Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-hydroxypyruvic acid
go back to main search page
Accession:CHEBI:30841 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.
Synonyms:related_synonym: 3-Hydroxy-2-oxopropanoic acid;   Formula=C3H4O4;   Hydroxypyruvic acid;   InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7);   InChIKey=HHDDCCUIIUWNGJ-UHFFFAOYSA-N;   SMILES=OCC(=O)C(O)=O
 alt_id: CHEBI:20083;   CHEBI:39999;   CHEBI:5813
 xref: Beilstein:1721079;   CAS:1113-60-6;   DrugBank:DB02951;   HMDB:HMDB0001352;   KEGG:C00168;   KNApSAcK:C00007563
 xref_mesh: MESH:C012375
 xref: PDBeChem:3PY;   PMID:13163046;   PMID:13328834;   PMID:13522577;   PMID:13522578;   PMID:13564115;   PMID:13798280;   PMID:20989501;   Reaxys:1721079;   Wikipedia:Hydroxypyruvic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:17180


show annotations for term's descendants           Sort by:
 
3-hydroxypyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      biological role 19804
        biochemical role 19339
          cofactor 15554
            pyruvic acid 47
              3-hydroxypyruvic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        monocarboxylic acid 17494
                                          fatty acid 15997
                                            saturated fatty acid 15972
                                              propionic acid 3672
                                                pyruvic acid 47
                                                  3-hydroxypyruvic acid 2
paths to the root