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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-hydroxypyruvic acid
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Accession:CHEBI:30841 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.
Synonyms:related_synonym: 3-Hydroxy-2-oxopropanoic acid;   Formula=C3H4O4;   Hydroxypyruvic acid;   InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7);   InChIKey=HHDDCCUIIUWNGJ-UHFFFAOYSA-N;   SMILES=OCC(=O)C(O)=O
 alt_id: CHEBI:20083;   CHEBI:39999;   CHEBI:5813
 xref: CAS:1113-60-6;   DrugBank:DB02951;   HMDB:HMDB0001352;   KEGG:C00168;   KNApSAcK:C00007563
 xref_mesh: MESH:C012375
 xref: PDBeChem:3PY;   PMID:13163046;   PMID:13328834;   PMID:13522577;   PMID:13522578;   PMID:13564115;   PMID:13798280;   PMID:20989501;   Reaxys:1721079;   Wikipedia:Hydroxypyruvic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:17180


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3-hydroxypyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        biochemical role 19574
          cofactor 16592
            pyruvic acid 53
              3-hydroxypyruvic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            heteroorganic entity 19532
                              organochalcogen compound 19293
                                organooxygen compound 19209
                                  carbon oxoacid 18678
                                    carboxylic acid 18675
                                      monocarboxylic acid 18027
                                        fatty acid 16860
                                          saturated fatty acid 16575
                                            propionic acid 3876
                                              pyruvic acid 53
                                                3-hydroxypyruvic acid 2
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