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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-hydroxypyruvic acid
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Accession:CHEBI:30841 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.
Synonyms:related_synonym: 3-Hydroxy-2-oxopropanoic acid;   Formula=C3H4O4;   Hydroxypyruvic acid;   InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7);   InChIKey=HHDDCCUIIUWNGJ-UHFFFAOYSA-N;   SMILES=OCC(=O)C(O)=O
 alt_id: CHEBI:20083;   CHEBI:39999;   CHEBI:5813
 xref: Beilstein:1721079;   CAS:1113-60-6;   DrugBank:DB02951;   HMDB:HMDB0001352;   KEGG:C00168;   KNApSAcK:C00007563
 xref_mesh: MESH:C012375
 xref: PDBeChem:3PY;   PMID:13163046;   PMID:13328834;   PMID:13522577;   PMID:13522578;   PMID:13564115;   PMID:13798280;   PMID:20989501;   Reaxys:1721079;   Wikipedia:Hydroxypyruvic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:17180

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3-hydroxypyruvic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to hydroxypyruvic acid CTD PMID:21376711 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          cofactor 15798
            pyruvic acid 47
              3-hydroxypyruvic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        monocarboxylic acid 17622
                                          fatty acid 16011
                                            saturated fatty acid 15986
                                              propionic acid 3693
                                                pyruvic acid 47
                                                  3-hydroxypyruvic acid 2
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