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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:adipic acid
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Accession:CHEBI:30832 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.
Synonyms:exact_synonym: hexanedioic acid
 related_synonym: 1,4-butanedicarboxylic acid;   1,6-hexanedioic acid;   Adipinsaeure;   E 355;   E355;   Formula=C6H10O4;   INS No. 355;   InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10);   InChIKey=WNLRTRBMVRJNCN-UHFFFAOYSA-N;   SMILES=OC(=O)CCCCC(O)=O;   adipinic acid
 alt_id: CHEBI:22268;   CHEBI:2489
 xref: Beilstein:1209788;   CAS:124-04-9;   Drug_Central:3474;   FAO/WHO_standards:174;   Gmelin:3166;   HMDB:HMDB0000448;   KEGG:C06104;   KEGG:D08839;   KNApSAcK:C00001178;   LIPID_MAPS_instance:LMFA01170048
 xref_mesh: MESH:C029900
 xref: MetaCyc:ADIPATE;   PDBeChem:0L1;   PMID:22770225;   PMID:24491734;   PMID:24895214;   Reaxys:1209788;   Wikipedia:Adipic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30833


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adipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; adipic acid inhibits the reaction [SLC22A6 protein results in increased transport of 2-amino-3-(2-amino-2-carboxyethylsulfanyl-mercuricsulfanyl)-propionic acid analog] CTD PMID:12606766, PMID:15284288 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
2-oxoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of alpha-ketoadipic acid CTD PMID:20567778 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
bis(2-ethylhexyl) adipate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor decreases expression EXP dioctyl adipate results in decreased expression of GRN mRNA CTD PMID:16493179 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases activity ISO dioctyl adipate results in decreased activity of HSD11B1 protein CTD PMID:16184081 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 decreases expression EXP dioctyl adipate results in decreased expression of NOLC1 mRNA CTD PMID:16493179 NCBI chr 1:265,829,055...265,839,819
Ensembl chr 1:265,829,108...265,839,818
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        food additive 14684
          food acidity regulator 11585
            adipic acid 5
              2,3,5-trihydroxy-4-phosphonooxyadipic acid 0
              2-amino-3-oxoadipic acid 0
              2-chloro-3-oxoadipic acid 0
              2-hydroxy-3-oxoadipic acid 0
              2-hydroxyadipic acid + 0
              2-oxoadipic acid 1
              3-aminoadipic acid + 0
              3-methyladipic acid 0
              3-oxoadipic acid + 0
              4-hydroxy-4-methyl-2-oxoadipic acid 0
              5-adenylyl-2-aminoadipic acid 0
              6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
              L-2-aminoadipic acid + 0
              O-adipoylcarnitine + 0
              adipoyl-CoA + 0
              bis(2-ethylhexyl) adipate 3
              di-(N-succinimidyl) adipate 0
              hexanedioyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      dicarboxylic acids and O-substituted derivatives 10271
                                        dicarboxylic acid 10264
                                          alpha,omega-dicarboxylic acid 2773
                                            adipic acid 5
                                              2,3,5-trihydroxy-4-phosphonooxyadipic acid 0
                                              2-amino-3-oxoadipic acid 0
                                              2-chloro-3-oxoadipic acid 0
                                              2-hydroxy-3-oxoadipic acid 0
                                              2-hydroxyadipic acid + 0
                                              2-oxoadipic acid 1
                                              3-aminoadipic acid + 0
                                              3-methyladipic acid 0
                                              3-oxoadipic acid + 0
                                              4-hydroxy-4-methyl-2-oxoadipic acid 0
                                              5-adenylyl-2-aminoadipic acid 0
                                              6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
                                              L-2-aminoadipic acid + 0
                                              O-adipoylcarnitine + 0
                                              adipoyl-CoA + 0
                                              bis(2-ethylhexyl) adipate 3
                                              di-(N-succinimidyl) adipate 0
                                              hexanedioyl group 0
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