Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:adipic acid
go back to main search page
Accession:CHEBI:30832 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.
Synonyms:exact_synonym: hexanedioic acid
 related_synonym: 1,4-butanedicarboxylic acid;   1,6-hexanedioic acid;   Adipinsaeure;   E 355;   E355;   Formula=C6H10O4;   INS No. 355;   InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10);   InChIKey=WNLRTRBMVRJNCN-UHFFFAOYSA-N;   SMILES=OC(=O)CCCCC(O)=O;   adipinic acid
 alt_id: CHEBI:22268;   CHEBI:2489
 xref: Beilstein:1209788;   CAS:124-04-9;   Drug_Central:3474;   FAO/WHO_standards:174;   Gmelin:3166;   HMDB:HMDB0000448;   KEGG:C06104;   KEGG:D08839;   KNApSAcK:C00001178;   LIPID_MAPS_instance:LMFA01170048
 xref_mesh: MESH:C029900
 xref: MetaCyc:ADIPATE;   PDBeChem:0L1;   PMID:22770225;   PMID:24491734;   PMID:24895214;   Reaxys:1209788;   Wikipedia:Adipic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30833


show annotations for term's descendants           Sort by:
adipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; adipic acid inhibits the reaction [SLC22A6 protein results in increased transport of 2-amino-3-(2-amino-2-carboxyethylsulfanyl-mercuricsulfanyl)-propionic acid analog] CTD PMID:12606766 PMID:15284288 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
2-oxoadipic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of alpha-ketoadipic acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
bis(2-ethylhexyl) adipate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grn granulin precursor decreases expression EXP dioctyl adipate results in decreased expression of GRN mRNA CTD PMID:16493179 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases activity ISO dioctyl adipate results in decreased activity of HSD11B1 protein CTD PMID:16184081 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 decreases expression EXP dioctyl adipate results in decreased expression of NOLC1 mRNA CTD PMID:16493179 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      application 19557
        food additive 15861
          food acidity regulator 11840
            adipic acid 5
              2,3,5-trihydroxy-4-phosphonooxyadipic acid 0
              2,4-dichloro-3-oxoadipic acid 0
              2-amino-3-oxoadipic acid 0
              2-chloro-3-oxoadipic acid 0
              2-hydroxy-3-oxoadipic acid 0
              2-hydroxyadipic acid + 0
              2-oxoadipic acid 1
              3-aminoadipic acid + 0
              3-methyladipic acid 0
              3-oxoadipic acid + 0
              4-hydroxy-4-methyl-2-oxoadipic acid 0
              5-adenylyl-2-aminoadipic acid 0
              6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
              L-2-aminoadipic acid + 0
              O-adipoylcarnitine + 0
              adipoyl-CoA + 0
              bis(2-ethylhexyl) adipate 3
              di-(N-succinimidyl) adipate 0
              hexanedioyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19644
                        carbon atom 19640
                          organic molecular entity 19640
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18799
                                    carbonyl compound 18799
                                      carboxylic acid 18515
                                        monocarboxylic acid 17853
                                          fatty acid 16521
                                            fatty acid derivative 8892
                                              dicarboxylic fatty acid 2639
                                                adipic acid 5
                                                  2,3,5-trihydroxy-4-phosphonooxyadipic acid 0
                                                  2,4-dichloro-3-oxoadipic acid 0
                                                  2-amino-3-oxoadipic acid 0
                                                  2-chloro-3-oxoadipic acid 0
                                                  2-hydroxy-3-oxoadipic acid 0
                                                  2-hydroxyadipic acid + 0
                                                  2-oxoadipic acid 1
                                                  3-aminoadipic acid + 0
                                                  3-methyladipic acid 0
                                                  3-oxoadipic acid + 0
                                                  4-hydroxy-4-methyl-2-oxoadipic acid 0
                                                  5-adenylyl-2-aminoadipic acid 0
                                                  6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
                                                  L-2-aminoadipic acid + 0
                                                  O-adipoylcarnitine + 0
                                                  adipoyl-CoA + 0
                                                  bis(2-ethylhexyl) adipate 3
                                                  di-(N-succinimidyl) adipate 0
                                                  hexanedioyl group 0
paths to the root