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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:vanillic acid
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Accession:CHEBI:30816 term browser browse the term
Definition:A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3.
Synonyms:related_synonym: 4-Hydroxy-3-methoxybenzoic acid;   Formula=C8H8O4;   InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11);   InChIKey=WKOLLVMJNQIZCI-UHFFFAOYSA-N;   SMILES=COc1cc(ccc1O)C(O)=O
 alt_id: CHEBI:27278;   CHEBI:9933
 xref: Beilstein:2208364;   CAS:121-34-6;   DrugBank:DB02130;   Gmelin:1472811;   HMDB:HMDB0000484;   KEGG:C06672;   KNApSAcK:C00002682
 xref_mesh: MESH:D014641
 xref: PDBeChem:VNL;   PMID:20482617;   PMID:24078147;   PMID:24314059;   YMDB:YMDB01802
 cyclic_relationship: is_conjugate_acid_of CHEBI:16632


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vanillic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA] CTD PMID:25794854 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA] CTD PMID:25794854 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA] CTD PMID:25794854 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA] CTD PMID:25794854 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G LOC100912605 olfactory receptor 5D14-like multiple interactions ISO Vanillic Acid analog binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link
G Mir122 microRNA 122 decreases expression ISO Vanillic Acid results in decreased expression of MIR122 mRNA CTD PMID:24165878 NCBI chr18:60,755,285...60,755,369 JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO Vanillic Acid results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Vanillic Acid CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Vanillic Acid CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            eukaryotic metabolite 18906
              plant metabolite 17359
                vanillic acid 9
                  (+)-(7S,8S)-guaiacylglycerol-beta-vanillic acid ether 0
                  1-O-vanilloyl-beta-D-glucose 0
                  3-O-vanillyceanothic acid 0
                  litseaefoloside C 0
                  methyl vanillate + 0
                  tschimganine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        aromatic carboxylic acid 10889
                                          benzoic acids 10858
                                            benzoic acid 3839
                                              hydroxybenzoic acid 3227
                                                monohydroxybenzoic acid 1264
                                                  vanillic acid 9
                                                    (+)-(7S,8S)-guaiacylglycerol-beta-vanillic acid ether 0
                                                    1-O-vanilloyl-beta-D-glucose 0
                                                    3-O-vanillyceanothic acid 0
                                                    litseaefoloside C 0
                                                    methyl vanillate + 0
                                                    tschimganine 0
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