Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dodecanoic acid
go back to main search page
Accession:CHEBI:30805 term browser browse the term
Definition:A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
Synonyms:related_synonym: 1-undecanecarboxylic acid;   ABL;   C12 fatty acid;   C12:0;   CH3-[CH2]10-COOH;   Coconut oil fatty acids;   DAO;   Dodecylcarboxylate;   Dodecylic acid;   Duodecyclic acid;   Duodecylic acid;   Formula=C12H24O2;   InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14);   InChIKey=POULHZVOKOAJMA-UHFFFAOYSA-N;   Laurinsaeure;   Laurostearic acid;   N-dodecanoic acid;   SMILES=CCCCCCCCCCCC(O)=O;   Undecane-1-carboxylic acid;   Vulvic acid;   dodecoic acid;   lauric acid
 alt_id: CHEBI:23864;   CHEBI:23865;   CHEBI:41882;   CHEBI:4680
 xref: Beilstein:1099477;   CAS:143-07-7;   DrugBank:DB03017;   Drug_Central:4642;   Gmelin:103520;   HMDB:HMDB0000638;   KEGG:C02679;   KNApSAcK:C00001221;   LIPID_MAPS_instance:LMFA01010012
 xref_mesh: MESH:C030358
 xref: MetaCyc:DODECANOATE;   PDBeChem:DAO;   PMID:19387482;   PMID:26884207;   Reaxys:1099477;   UM-BBD_compID:c0566;   Wikipedia:Lauric_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:18262



show annotations for term's descendants           Sort by:
 
dodecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO lauric acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] CTD PMID:19428350 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of lauric acid CTD PMID:12464242 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 affects metabolic processing EXP CYP4A1 protein affects the metabolism of lauric acid CTD PMID:15879494 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 affects metabolic processing EXP CYP4A2 protein affects the metabolism of lauric acid CTD PMID:15879494 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 affects metabolic processing EXP CYP4A3 protein affects the metabolism of lauric acid CTD PMID:15879494 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 multiple interactions ISO lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine] CTD PMID:9310344 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions ISO Curcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]]; lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein] CTD PMID:18413660 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO lauric acid binds to PPARA protein CTD PMID:10403814 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO lauric acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity
ISO Curcumin inhibits the reaction [lauric acid results in increased activity of RELA protein]; parthenolide inhibits the reaction [lauric acid results in increased activity of RELA protein] CTD PMID:18413660 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of lauric acid CTD PMID:16051554 NCBI chr 9:88,791,216...88,808,465 JBrowse link
1-monolauroylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO 1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
12-hydroxylauric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide affects binding
increases oxidation
ISO 12-hydroxydodecanoic acid binds to ADH5 protein
ADH5 protein results in increased oxidation of 12-hydroxydodecanoic acid
CTD PMID:12196016 PMID:12604204 PMID:19428350 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 multiple interactions
increases chemical synthesis
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [CYP4V2 protein results in increased chemical synthesis of 12-hydroxydodecanoic acid] CTD PMID:28729181 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
JBrowse link
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link
methyl laurate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO lauric acid methyl ester binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of ESR2 protein; lauric acid methyl ester binds to and results in increased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Pgr progesterone receptor multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of THRB protein CTD PMID:27633901 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
perfluorododecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd14b abhydrolase domain containing 14b decreases expression EXP perfluorododecanoic acid results in decreased expression of ABHD14B protein CTD PMID:26168851 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression
multiple interactions
EXP perfluorododecanoic acid results in increased expression of ACOT1 mRNA; perfluorododecanoic acid results in increased expression of ACOT1 protein
perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of ACOT1 mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of ACOT1 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT1 mRNA]
CTD PMID:26168851 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions
increases expression
EXP perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of ACOT2 mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of ACOT2 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT2 mRNA]
perfluorododecanoic acid results in increased expression of ACOT2 mRNA; perfluorododecanoic acid results in increased expression of ACOT2 protein
CTD PMID:26168851 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acp1 acid phosphatase 1 increases expression EXP perfluorododecanoic acid results in increased expression of ACP1 protein CTD PMID:19854247 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of ACTG1 protein CTD PMID:26168851 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Acy1 aminoacylase 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of ACY1 protein CTD PMID:26168851 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
JBrowse link
G Adk adenosine kinase decreases expression EXP perfluorododecanoic acid results in decreased expression of ADK protein CTD PMID:26168851 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression EXP perfluorododecanoic acid results in decreased expression of AHCY protein CTD PMID:26168851 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Akap4 A-kinase anchoring protein 4 increases expression
decreases expression
EXP perfluorododecanoic acid results in increased expression of AKAP4 mRNA
perfluorododecanoic acid results in decreased expression of AKAP4 protein
CTD PMID:19854247 NCBI chr  X:15,435,391...15,445,684
Ensembl chr  X:15,435,410...15,445,684
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases phosphorylation EXP perfluorododecanoic acid results in decreased phosphorylation of AKT2 protein CTD PMID:30489073 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alb albumin increases expression
decreases expression
EXP perfluorododecanoic acid results in increased expression of ALB protein
perfluorododecanoic acid results in decreased expression of ALB protein
CTD PMID:19854247 PMID:26168851 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression
multiple interactions
EXP perfluorododecanoic acid results in decreased expression of ALDH2 protein
PPARA mRNA promotes the reaction [perfluorododecanoic acid results in decreased expression of ALDH2 protein]
CTD PMID:26168851 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 decreases expression EXP perfluorododecanoic acid results in decreased expression of ALDH9A1 protein CTD PMID:26168851 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluorododecanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Apoa2 apolipoprotein A2 affects expression ISO perfluorododecanoic acid affects the expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP perfluorododecanoic acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Ar androgen receptor affects expression EXP perfluorododecanoic acid affects the expression of AR mRNA CTD PMID:19397962 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression EXP perfluorododecanoic acid results in increased expression of ARHGDIB protein CTD PMID:19854247 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO perfluorododecanoic acid results in increased expression of ATF3 mRNA CTD PMID:23567314 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression EXP perfluorododecanoic acid results in decreased expression of ATP5H mRNA CTD PMID:19854247 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO perfluorododecanoic acid results in decreased expression of BAAT mRNA CTD PMID:23567314 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO perfluorododecanoic acid results in increased expression of CCND1 mRNA CTD PMID:23567314 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd36 CD36 molecule increases expression EXP perfluorododecanoic acid results in increased expression of CD36 mRNA CTD PMID:23353032 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdh5 cadherin 5 affects expression ISO perfluorododecanoic acid affects the expression of CDH5 protein CTD PMID:33677611 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Cops4 COP9 signalosome subunit 4 increases expression EXP perfluorododecanoic acid results in increased expression of COPS4 protein CTD PMID:26168851 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Cops8 COP9 signalosome subunit 8 decreases expression EXP perfluorododecanoic acid results in decreased expression of COPS8 protein CTD PMID:19854247 NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression
increases expression
EXP perfluorododecanoic acid results in decreased expression of COX5A protein
perfluorododecanoic acid results in increased expression of COX5A mRNA
CTD PMID:19854247 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression EXP perfluorododecanoic acid results in increased expression of COX5B mRNA CTD PMID:19854247 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression
multiple interactions
EXP perfluorododecanoic acid results in decreased expression of CPS1 mRNA; perfluorododecanoic acid results in decreased expression of CPS1 protein
PPARA mRNA inhibits the reaction [perfluorododecanoic acid results in decreased expression of CPS1 mRNA]
CTD PMID:26168851 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression ISO perfluorododecanoic acid affects the expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crym crystallin, mu decreases expression EXP perfluorododecanoic acid results in decreased expression of CRYM protein CTD PMID:26168851 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
JBrowse link
G Csk C-terminal Src kinase decreases expression EXP perfluorododecanoic acid results in decreased expression of CSK mRNA; perfluorododecanoic acid results in decreased expression of CSK protein CTD PMID:19854247 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Ctsa cathepsin A increases expression EXP perfluorododecanoic acid results in increased expression of CTSA protein CTD PMID:26168851 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression EXP perfluorododecanoic acid results in decreased expression of CUTA protein CTD PMID:19854247 NCBI chr20:5,022,956...5,024,580
Ensembl chr20:5,022,956...5,024,552
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of CYP11A1 mRNA; perfluorododecanoic acid results in decreased expression of CYP11A1 protein CTD PMID:17400581 PMID:19397962 PMID:19429406 PMID:30489073 PMID:33774092 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of CYP17A1 mRNA; perfluorododecanoic acid results in decreased expression of CYP17A1 protein CTD PMID:17400581 PMID:30489073 PMID:33774092 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO perfluorododecanoic acid results in decreased expression of CYP1A1 mRNA CTD PMID:23567314 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO perfluorododecanoic acid results in decreased expression of CYP2B10 mRNA CTD PMID:23567314 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression ISO perfluorododecanoic acid results in decreased expression of CYP3A4 mRNA CTD PMID:23567314 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of CYP4A1 mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of CYP4A1 mRNA]
perfluorododecanoic acid results in increased expression of CYP4A1 mRNA
CTD PMID:26168851 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO perfluorododecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP perfluorododecanoic acid results in increased expression of DDAH1 protein CTD PMID:26168851 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO perfluorododecanoic acid results in increased expression of DDIT3 mRNA CTD PMID:23567314 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddt D-dopachrome tautomerase decreases expression EXP perfluorododecanoic acid results in decreased expression of DDT protein CTD PMID:19854247 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
JBrowse link
G Dhh desert hedgehog signaling molecule decreases expression EXP perfluorododecanoic acid results in decreased expression of DHH mRNA; perfluorododecanoic acid results in decreased expression of DHH protein CTD PMID:33774092 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression EXP perfluorododecanoic acid results in increased expression of DLAT protein CTD PMID:26168851 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression
multiple interactions
EXP perfluorododecanoic acid results in increased expression of ECH1 mRNA; perfluorododecanoic acid results in increased expression of ECH1 protein
PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ECH1 mRNA]
CTD PMID:26168851 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Efhd2 EF-hand domain family, member D2 decreases expression EXP perfluorododecanoic acid results in decreased expression of EFHD2 protein CTD PMID:19854247 NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of ESR1 mRNA CTD PMID:19429406 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP perfluorododecanoic acid results in decreased expression of ESR2 mRNA CTD PMID:19429406 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase decreases expression EXP perfluorododecanoic acid results in decreased expression of ETHE1 protein CTD PMID:26168851 NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO perfluorododecanoic acid results in decreased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fasn fatty acid synthase decreases expression EXP perfluorododecanoic acid results in decreased expression of FASN mRNA CTD PMID:23353032 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP perfluorododecanoic acid results in increased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase increases expression EXP perfluorododecanoic acid results in increased expression of FHIT protein CTD PMID:19854247 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
decreases secretion
EXP perfluorododecanoic acid results in decreased expression of FSHB mRNA; perfluorododecanoic acid results in decreased expression of FSHB protein
perfluorododecanoic acid results in decreased secretion of FSHB protein
CTD PMID:19397962 PMID:30489073 PMID:33774092 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP perfluorododecanoic acid results in decreased expression of FSHR mRNA; perfluorododecanoic acid results in decreased expression of FSHR protein CTD PMID:33774092 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression
increases expression
EXP perfluorododecanoic acid results in decreased expression of FTH1 protein
perfluorododecanoic acid results in increased expression of FTH1 mRNA
CTD PMID:19854247 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO perfluorododecanoic acid results in increased expression of GADD45B mRNA CTD PMID:23567314 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gc GC, vitamin D binding protein decreases expression EXP perfluorododecanoic acid results in decreased expression of GC protein CTD PMID:26168851 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gk glycerol kinase decreases expression ISO perfluorododecanoic acid results in decreased expression of GK mRNA CTD PMID:23567314 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression EXP perfluorododecanoic acid results in decreased expression of GLOD4 protein CTD PMID:19854247 NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
JBrowse link
G Gmfb glia maturation factor, beta decreases expression EXP perfluorododecanoic acid results in decreased expression of GMFB protein CTD PMID:26168851 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
JBrowse link
G Gmfg glia maturation factor, gamma increases expression EXP perfluorododecanoic acid results in increased expression of GMFG protein CTD PMID:19854247 NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor decreases expression EXP perfluorododecanoic acid results in decreased expression of GNRHR mRNA CTD PMID:19397962 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases expression EXP perfluorododecanoic acid results in increased expression of GPD1 protein CTD PMID:26168851 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha decreases expression
affects response to substance
EXP perfluorododecanoic acid results in decreased expression of GSK3A protein; perfluorododecanoic acid results in decreased expression of GSK3A protein modified form
GSK3A protein affects the susceptibility to perfluorododecanoic acid
CTD PMID:23353032 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects response to substance
decreases expression
EXP GSK3B protein affects the susceptibility to perfluorododecanoic acid
perfluorododecanoic acid results in decreased expression of GSK3B protein; perfluorododecanoic acid results in decreased expression of GSK3B protein modified form
CTD PMID:23353032 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase increases expression EXP perfluorododecanoic acid results in increased expression of HAAO protein CTD PMID:26168851 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha affects expression
multiple interactions
increases expression
ISO
EXP
perfluorododecanoic acid affects the expression of HADHA mRNA
PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of HADHA mRNA]
perfluorododecanoic acid results in increased expression of HADHA mRNA; perfluorododecanoic acid results in increased expression of HADHA protein
CTD PMID:22071372 PMID:23567314 PMID:26168851 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP perfluorododecanoic acid results in increased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hhex hematopoietically expressed homeobox increases expression EXP perfluorododecanoic acid results in increased expression of HHEX mRNA CTD PMID:22071372 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO perfluorododecanoic acid results in decreased expression of HMGCS2 mRNA CTD PMID:23567314 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO perfluorododecanoic acid results in increased expression of HMOX1 mRNA CTD PMID:23567314 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpx hemopexin increases expression EXP perfluorododecanoic acid results in increased expression of HPX protein CTD PMID:26168851 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of HSD11B1 mRNA; perfluorododecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:30489073 PMID:33774092 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of HSD17B1 mRNA CTD PMID:19429406 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects expression EXP perfluorododecanoic acid affects the expression of HSD17B2 mRNA CTD PMID:33774092 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression
affects expression
EXP perfluorododecanoic acid results in decreased expression of HSD17B3 mRNA
perfluorododecanoic acid affects the expression of HSD17B3 protein
CTD PMID:17400581 PMID:33774092 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
affects expression
EXP perfluorododecanoic acid results in decreased expression of HSD3B1 mRNA; perfluorododecanoic acid results in decreased expression of HSD3B1 protein
perfluorododecanoic acid affects the expression of HSD3B1 mRNA; perfluorododecanoic acid affects the expression of HSD3B1 protein
CTD PMID:17400581 PMID:33774092 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects expression EXP perfluorododecanoic acid affects the expression of HSPA5 protein CTD PMID:26168851 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP perfluorododecanoic acid results in increased expression of HSPA8 protein CTD PMID:26168851 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP perfluorododecanoic acid results in increased expression of HSPA9 protein CTD PMID:26168851 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP perfluorododecanoic acid results in increased expression of HSPD1 protein CTD PMID:26168851 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression EXP perfluorododecanoic acid results in decreased expression of IDH3A protein CTD PMID:26168851 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression EXP perfluorododecanoic acid results in increased expression of IDO1 protein CTD PMID:19854247 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ift20 intraflagellar transport 20 decreases expression EXP perfluorododecanoic acid results in decreased expression of IFT20 protein CTD PMID:19854247 NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of IGF1 mRNA CTD PMID:19397962 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression EXP perfluorododecanoic acid results in decreased expression of IGF1R mRNA CTD PMID:19397962 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Il1a interleukin 1 alpha decreases expression EXP perfluorododecanoic acid results in decreased expression of IL1A mRNA CTD PMID:19397962 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Impa1 inositol monophosphatase 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of IMPA1 protein CTD PMID:19854247 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of IRS1 protein modified form CTD PMID:23353032 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itga1 integrin subunit alpha 1 affects expression ISO perfluorododecanoic acid affects the expression of ITGA1 protein CTD PMID:33677611 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
JBrowse link
G Itpa inosine triphosphatase increases expression EXP perfluorododecanoic acid results in increased expression of ITPA protein CTD PMID:26168851 NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression EXP perfluorododecanoic acid results in decreased expression of IVD protein CTD PMID:26168851 NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
JBrowse link
G Krt10 keratin 10 decreases expression EXP perfluorododecanoic acid results in decreased expression of KRT10 protein CTD PMID:19854247 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt14 keratin 14 decreases expression EXP perfluorododecanoic acid results in decreased expression of KRT14 protein CTD PMID:19854247 NCBI chr10:85,137,932...85,141,990
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt16 keratin 16 decreases expression EXP perfluorododecanoic acid results in decreased expression of KRT16 protein CTD PMID:19854247 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Krt8 keratin 8 increases expression EXP perfluorododecanoic acid results in increased expression of KRT8 protein CTD PMID:26168851 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
decreases secretion
EXP perfluorododecanoic acid results in decreased expression of LHB mRNA; perfluorododecanoic acid results in decreased expression of LHB protein
perfluorododecanoic acid results in decreased secretion of LHB protein
CTD PMID:17400581 PMID:19397962 PMID:30489073 PMID:33774092 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression
affects expression
EXP perfluorododecanoic acid results in decreased expression of LHCGR mRNA; perfluorododecanoic acid results in decreased expression of LHCGR protein
perfluorododecanoic acid affects the expression of LHCGR mRNA; perfluorododecanoic acid affects the expression of LHCGR protein
CTD PMID:19429406 PMID:30489073 PMID:33774092 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase decreases expression EXP perfluorododecanoic acid results in decreased expression of LHPP protein CTD PMID:26168851 NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression ISO perfluorododecanoic acid results in decreased expression of MBL2 mRNA CTD PMID:23567314 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mdh1 malate dehydrogenase 1 increases expression EXP perfluorododecanoic acid results in increased expression of MDH1 protein CTD PMID:26168851 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of PZP protein CTD PMID:26168851 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression EXP perfluorododecanoic acid results in increased expression of NDUFV2 protein CTD PMID:26168851 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO perfluorododecanoic acid results in increased expression of NOS2 mRNA CTD PMID:23567314 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO perfluorododecanoic acid results in increased activity of NR1I2 protein CTD PMID:28115241 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ntan1 N-terminal asparagine amidase increases expression EXP perfluorododecanoic acid results in increased expression of NTAN1 protein CTD PMID:19854247 NCBI chr10:2,111,085...2,126,123 JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression EXP perfluorododecanoic acid results in decreased expression of P4HB protein CTD PMID:26168851 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Park7 Parkinsonism associated deglycase decreases expression EXP perfluorododecanoic acid results in decreased expression of PARK7 protein CTD PMID:19854247 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pax8 paired box 8 increases expression EXP perfluorododecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of PBLD1 protein CTD PMID:26168851 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta increases expression EXP perfluorododecanoic acid results in increased expression of PDHB protein CTD PMID:26168851 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP perfluorododecanoic acid affects the expression of PDIA6 protein CTD PMID:26168851 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluorododecanoic acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases activity
decreases expression
EXP perfluorododecanoic acid results in decreased activity of PDPK1 protein
perfluorododecanoic acid results in decreased expression of PDPK1 protein; perfluorododecanoic acid results in decreased expression of PDPK1 protein modified form
CTD PMID:23353032 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression
increases expression
EXP perfluorododecanoic acid results in decreased expression of PEBP1 protein
perfluorododecanoic acid results in increased expression of PEBP1 mRNA
CTD PMID:19854247 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Phb prohibitin increases expression EXP perfluorododecanoic acid results in increased expression of PHB protein CTD PMID:26168851 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Pitpna phosphatidylinositol transfer protein, alpha decreases expression EXP perfluorododecanoic acid results in decreased expression of PITPNA protein CTD PMID:19854247 NCBI chr10:60,430,712...60,473,564
Ensembl chr10:60,430,748...60,471,342
JBrowse link
G Plin2 perilipin 2 increases expression
affects expression
ISO perfluorododecanoic acid results in increased expression of PLIN2 mRNA
perfluorododecanoic acid affects the expression of PLIN2 mRNA
CTD PMID:23567314 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO perfluorododecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity
increases response to substance
increases expression
multiple interactions
ISO
EXP
perfluorododecanoic acid results in increased activity of PPARA protein
PPARA mRNA results in increased susceptibility to perfluorododecanoic acid
perfluorododecanoic acid results in increased expression of PPARA mRNA; perfluorododecanoic acid results in increased expression of PPARA protein
perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of PPARA mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of PPARA mRNA]; PPARA mRNA inhibits the reaction [perfluorododecanoic acid results in decreased expression of CPS1 mRNA]; PPARA mRNA inhibits the reaction [perfluorododecanoic acid results in increased abundance of Reactive Oxygen Species]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in decreased expression of ALDH2 protein]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT1 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT2 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ECH1 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of HADHA mRNA]
CTD PMID:22107727 PMID:26168851 PMID:28857218 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO perfluorododecanoic acid results in increased expression of PPARD mRNA CTD PMID:23567314 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO perfluorododecanoic acid results in increased activity of PPARG protein CTD PMID:23391484 PMID:24998974 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression EXP perfluorododecanoic acid results in decreased expression of PPARGC1A protein CTD PMID:30489073 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression EXP perfluorododecanoic acid results in decreased expression of PRDX2 protein CTD PMID:26168851 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx4 peroxiredoxin 4 decreases expression EXP perfluorododecanoic acid results in decreased expression of PRDX4 protein CTD PMID:26168851 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Psmf1 proteasome inhibitor subunit 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of PSMF1 protein CTD PMID:19854247 NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluorododecanoic acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ranbp1 RAN binding protein 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of RANBP1 protein CTD PMID:19854247 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
JBrowse link
G Rbp4 retinol binding protein 4 increases expression EXP perfluorododecanoic acid results in increased expression of RBP4 protein CTD PMID:26168851 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Rgn regucalcin decreases expression EXP perfluorododecanoic acid results in decreased expression of RGN protein CTD PMID:26168851 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression
affects expression
EXP perfluorododecanoic acid results in decreased expression of SCARB1 mRNA; perfluorododecanoic acid results in decreased expression of SCARB1 protein
perfluorododecanoic acid affects the expression of SCARB1 mRNA; perfluorododecanoic acid affects the expression of SCARB1 protein
CTD PMID:17400581 PMID:30489073 PMID:33774092 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
increases expression
ISO
EXP
perfluorododecanoic acid results in decreased expression of SCD mRNA
perfluorododecanoic acid results in increased expression of SCD1 mRNA
CTD PMID:23353032 PMID:23567314 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Serpind1 serpin family D member 1 decreases expression ISO perfluorododecanoic acid results in decreased expression of SERPIND1 mRNA CTD PMID:23567314 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Serpinf2 serpin family F member 2 decreases expression ISO perfluorododecanoic acid results in decreased expression of SERPINF2 mRNA CTD PMID:23567314 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of SIRT1 protein CTD PMID:30489073 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc25a20 solute carrier family 25 member 20 decreases expression ISO perfluorododecanoic acid results in decreased expression of SLC25A20 mRNA CTD PMID:23567314 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO perfluorododecanoic acid results in increased expression of SLC27A1 mRNA CTD PMID:23567314 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of SOD1 mRNA CTD PMID:19854247 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression EXP perfluorododecanoic acid results in decreased expression of SOX9 mRNA; perfluorododecanoic acid results in decreased expression of SOX9 protein CTD PMID:33774092 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 affects expression EXP perfluorododecanoic acid affects the expression of SRD5A1 mRNA CTD PMID:33774092 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP perfluorododecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:23353032 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
affects expression
decreases expression
ISO
EXP
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]
perfluorododecanoic acid affects the expression of STAR mRNA; perfluorododecanoic acid affects the expression of STAR protein
perfluorododecanoic acid results in decreased expression of STAR mRNA; perfluorododecanoic acid results in decreased expression of STAR protein
CTD PMID:17400581 PMID:19397962 PMID:19429406 PMID:20100736 PMID:30489073 More... NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP perfluorododecanoic acid results in decreased expression of STMN1 protein CTD PMID:19854247 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta increases expression EXP perfluorododecanoic acid results in increased expression of SUCLG2 protein CTD PMID:26168851 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 decreases expression EXP perfluorododecanoic acid results in decreased expression of SULT1C3 protein CTD PMID:26168851 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Suox sulfite oxidase increases expression EXP perfluorododecanoic acid results in increased expression of SUOX protein CTD PMID:26168851 NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO perfluorododecanoic acid binds to THRA protein CTD PMID:24819616 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP perfluorododecanoic acid results in increased expression of TPM1 protein CTD PMID:26168851 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Trap1 TNF receptor-associated protein 1 increases expression EXP perfluorododecanoic acid results in increased expression of TRAP1 protein CTD PMID:26168851 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
G Ttr transthyretin multiple interactions ISO perfluorododecanoic acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Txnip thioredoxin interacting protein affects expression ISO perfluorododecanoic acid affects the expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression EXP perfluorododecanoic acid results in decreased expression of UBE2N protein CTD PMID:19854247 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP perfluorododecanoic acid results in increased expression of UQCRC1 protein CTD PMID:26168851 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein decreases expression
increases expression
EXP perfluorododecanoic acid results in decreased expression of UQCRH protein
perfluorododecanoic acid results in increased expression of UQCRH mRNA
CTD PMID:19854247 NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon decreases expression
increases expression
EXP perfluorododecanoic acid results in decreased expression of YWHAE protein
perfluorododecanoic acid results in increased expression of YWHAE mRNA
CTD PMID:19854247 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
rac-1-monolauroylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO 1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19763
      biological role 19763
        antimicrobial agent 17482
          antibacterial agent 13981
            dodecanoic acid 173
              1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol 0
              1,2-didodecanoyl-sn-glycero-3-cytidine 5'-diphosphate 0
              1,2-dioleoyl-3-lauroyl-sn-glycerol 0
              1-O-(alpha-D-galactopyranosyl)-N-dodecanoylphytosphingosine 0
              1-octadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine 0
              10-hydroxylauric acid 0
              10-methyldodecanoic acid 0
              11-hydroxylauric acid + 0
              12-bromododecanoic acid 0
              12-hydroxylauric acid + 2
              12-oxododecanoic acid 0
              2-dodecanoyl-sn-glycero-3-phosphocholine 0
              2-hydroxydodecanoic acid + 0
              3,12-dihydroxylauric acid 0
              3-hydroxylauric acid + 0
              3-oxolauric acid + 0
              4-hydroxylauric acid + 0
              7-hydroxylauric acid 0
              8-hydroxylauric acid 0
              9-hydroxylauric acid 0
              L-erythro-N-dodecanoylsphingosine 0
              N-(dodecanoyl)ethanolamine 0
              N-dodecanoyl-(2S)-hydroxyglycine 0
              N-dodecanoylglycine 0
              N-dodecanoylphytosphingosine 0
              N-dodecanoylsphinganine 0
              N-dodecanoylsphingosine 0
              N-dodecanoylsphingosine 1-phosphate 0
              N-dodecanoyltaurine 0
              N-lauroyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 0
              S-dodecanoyl-4'-phosphopantetheine 0
              dilauroyl phosphatidylglycerol 0
              dodecanamide 0
              dodecanoate ester + 6
              dodecanoic anhydride 0
              dodecanoyl group 0
              dodecanoyl-AMP 0
              isopropyl dodecanoate 0
              kansuiphorin A 0
              kansuiphorin B 0
              lauroyl-CoA + 3
              perfluorododecanoic acid 158
              pescaprein XXI 0
              pescaprein XXII 0
              pescaprein XXV 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      carbon group element atom 19631
                        carbon atom 19621
                          organic molecular entity 19621
                            organic group 18730
                              organic divalent group 18721
                                organodiyl group 18721
                                  carbonyl group 18670
                                    carbonyl compound 18670
                                      carboxylic acid 18367
                                        monocarboxylic acid 17639
                                          fatty acid 16023
                                            saturated fatty acid 15997
                                              straight-chain saturated fatty acid 15451
                                                dodecanoic acid 173
                                                  1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol 0
                                                  1,2-didodecanoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                                                  1,2-dioleoyl-3-lauroyl-sn-glycerol 0
                                                  1-O-(alpha-D-galactopyranosyl)-N-dodecanoylphytosphingosine 0
                                                  1-octadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine 0
                                                  10-hydroxylauric acid 0
                                                  10-methyldodecanoic acid 0
                                                  11-hydroxylauric acid + 0
                                                  12-bromododecanoic acid 0
                                                  12-hydroxylauric acid + 2
                                                  12-oxododecanoic acid 0
                                                  2-dodecanoyl-sn-glycero-3-phosphocholine 0
                                                  2-hydroxydodecanoic acid + 0
                                                  3,12-dihydroxylauric acid 0
                                                  3-hydroxylauric acid + 0
                                                  3-oxolauric acid + 0
                                                  4-hydroxylauric acid + 0
                                                  7-hydroxylauric acid 0
                                                  8-hydroxylauric acid 0
                                                  9-hydroxylauric acid 0
                                                  L-erythro-N-dodecanoylsphingosine 0
                                                  N-(dodecanoyl)ethanolamine 0
                                                  N-dodecanoyl-(2S)-hydroxyglycine 0
                                                  N-dodecanoylglycine 0
                                                  N-dodecanoylphytosphingosine 0
                                                  N-dodecanoylsphinganine 0
                                                  N-dodecanoylsphingosine 0
                                                  N-dodecanoylsphingosine 1-phosphate 0
                                                  N-dodecanoyltaurine 0
                                                  N-lauroyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 0
                                                  S-dodecanoyl-4'-phosphopantetheine 0
                                                  dilauroyl phosphatidylglycerol 0
                                                  dodecanamide 0
                                                  dodecanoate ester + 6
                                                  dodecanoic anhydride 0
                                                  dodecanoyl group 0
                                                  dodecanoyl-AMP 0
                                                  isopropyl dodecanoate 0
                                                  kansuiphorin A 0
                                                  kansuiphorin B 0
                                                  lauroyl-CoA + 3
                                                  perfluorododecanoic acid 158
                                                  pescaprein XXI 0
                                                  pescaprein XXII 0
                                                  pescaprein XXV 0
paths to the root