|
G |
Adh5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
multiple interactions |
ISO |
lauric acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] |
CTD |
PMID:19428350 |
|
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
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|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:34506767 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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|
G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in increased cleavage of CASP3 protein] |
CTD |
PMID:34506767 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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|
G |
Cldn1 |
claudin 1 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] |
CTD |
PMID:34506767 |
|
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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|
G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
increases hydroxylation decreases hydroxylation |
ISO |
CYP2C9 protein results in increased hydroxylation of lauric acid CYP2C9 gene polymorphism results in decreased hydroxylation of lauric acid |
CTD |
PMID:9241660 PMID:11455026 |
|
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases metabolic processing |
ISO |
CYP2E1 protein results in increased metabolism of lauric acid |
CTD |
PMID:12464242 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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|
G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
affects metabolic processing |
EXP |
CYP4A1 protein affects the metabolism of lauric acid |
CTD |
PMID:15879494 |
|
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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|
G |
Cyp4a2 |
cytochrome P450, family 4, subfamily a, polypeptide 2 |
affects metabolic processing |
EXP |
CYP4A2 protein affects the metabolism of lauric acid |
CTD |
PMID:15879494 |
|
NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
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|
G |
Cyp4a3 |
cytochrome P450, family 4, subfamily a, polypeptide 3 |
affects metabolic processing |
EXP |
CYP4A3 protein affects the metabolism of lauric acid |
CTD |
PMID:15879494 |
|
NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
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|
G |
Cyp4b1 |
cytochrome P450, family 4, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [CYP4B1 protein results in increased metabolism of 3,3'-Dichlorobenzidine] |
CTD |
PMID:9310344 |
|
NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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|
G |
Krt20 |
keratin 20 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of KRT20 protein] |
CTD |
PMID:34506767 |
|
NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107
|
|
G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LGR5 protein] |
CTD |
PMID:34506767 |
|
NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
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|
G |
Lyz2 |
lysozyme 2 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LYZ protein] |
CTD |
PMID:34506767 |
|
NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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|
G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:34506767 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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|
G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of MUC2 protein] |
CTD |
PMID:34506767 |
|
NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
|
|
G |
Nod2 |
nucleotide-binding oligomerization domain containing 2 |
multiple interactions |
ISO |
Curcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]]; lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein] |
CTD |
PMID:18413660 |
|
NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
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|
G |
Ocln |
occludin |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] |
CTD |
PMID:34506767 |
|
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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|
G |
Pcna |
proliferating cell nuclear antigen |
increases expression multiple interactions |
ISO |
lauric acid results in increased expression of PCNA protein lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of PCNA protein] |
CTD |
PMID:34506767 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects binding |
ISO |
lauric acid binds to PPARA protein |
CTD |
PMID:10403814 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
lauric acid results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases activity |
ISO |
Curcumin inhibits the reaction [lauric acid results in increased activity of RELA protein]; parthenolide inhibits the reaction [lauric acid results in increased activity of RELA protein] |
CTD |
PMID:18413660 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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|
G |
Rps6 |
ribosomal protein S6 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6 protein] |
CTD |
PMID:34506767 |
|
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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|
G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:34506767 |
|
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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|
G |
Tjp1 |
tight junction protein 1 |
multiple interactions increases expression |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein] lauric acid results in increased expression of TJP1 protein |
CTD |
PMID:34506767 |
|
NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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|
G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
increases glucuronidation |
ISO |
UGT1A3 protein results in increased glucuronidation of lauric acid |
CTD |
PMID:16051554 |
|
NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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|
G |
Vil1 |
villin 1 |
multiple interactions |
ISO |
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of VIL1 protein] |
CTD |
PMID:34506767 |
|
NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858
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|
|
G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
|
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
|
|
|
G |
Adh5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
increases oxidation affects binding |
ISO |
ADH5 protein results in increased oxidation of 12-hydroxydodecanoic acid 12-hydroxydodecanoic acid binds to ADH5 protein |
CTD |
PMID:12196016 PMID:12604204 PMID:19428350 |
|
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
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|
G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
multiple interactions increases chemical synthesis |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [CYP4V2 protein results in increased chemical synthesis of 12-hydroxydodecanoic acid] |
CTD |
PMID:28729181 |
|
NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
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|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
|
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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|
G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein |
CTD |
PMID:25526675 |
|
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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|
G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[lauroyl-coenzyme A co-treated with NADP] binds to PECR protein |
CTD |
PMID:25526675 |
|
NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
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|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
lauric acid methyl ester binds to and results in increased activity of ESR1 protein |
CTD |
PMID:27633901 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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|
G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
lauric acid methyl ester binds to and results in decreased activity of ESR2 protein; lauric acid methyl ester binds to and results in increased activity of ESR2 protein |
CTD |
PMID:27633901 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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|
G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
lauric acid methyl ester binds to and results in decreased activity of PGR protein |
CTD |
PMID:27633901 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
lauric acid methyl ester binds to and results in decreased activity of PPARG protein |
CTD |
PMID:27633901 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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|
G |
Thrb |
thyroid hormone receptor beta |
multiple interactions |
ISO |
lauric acid methyl ester binds to and results in decreased activity of THRB protein |
CTD |
PMID:27633901 |
|
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
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|
G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of ABCA1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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|
G |
Abhd14b |
abhydrolase domain containing 14b |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ABHD14B protein |
CTD |
PMID:26168851 |
|
NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
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|
G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression multiple interactions |
EXP |
perfluorododecanoic acid results in increased expression of ACOT1 mRNA; perfluorododecanoic acid results in increased expression of ACOT1 protein perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of ACOT1 mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of ACOT1 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT1 mRNA] |
CTD |
PMID:26168851 |
|
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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|
G |
Acot2 |
acyl-CoA thioesterase 2 |
multiple interactions increases expression |
EXP ISO |
perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of ACOT2 mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of ACOT2 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT2 mRNA] perfluorododecanoic acid results in increased expression of ACOT2 mRNA; perfluorododecanoic acid results in increased expression of ACOT2 protein |
CTD |
PMID:26168851 PMID:35337807 |
|
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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|
G |
Acp1 |
acid phosphatase 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of ACP1 protein |
CTD |
PMID:19854247 |
|
NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
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G |
Actg1 |
actin, gamma 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ACTG1 protein |
CTD |
PMID:26168851 |
|
NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 Ensembl chr 3:105,619,737...105,624,232
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|
G |
Acy1 |
aminoacylase 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ACY1 protein |
CTD |
PMID:26168851 |
|
NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
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|
G |
Adk |
adenosine kinase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ADK protein |
CTD |
PMID:26168851 |
|
NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
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G |
Ahcy |
adenosylhomocysteinase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of AHCY protein |
CTD |
PMID:26168851 |
|
NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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|
G |
Akap4 |
A-kinase anchoring protein 4 |
increases expression decreases expression |
EXP |
perfluorododecanoic acid results in increased expression of AKAP4 mRNA perfluorododecanoic acid results in decreased expression of AKAP4 protein |
CTD |
PMID:19854247 |
|
NCBI chr X:15,435,391...15,445,684
Ensembl chr X:15,435,410...15,445,684
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G |
Akt2 |
AKT serine/threonine kinase 2 |
decreases phosphorylation |
EXP |
perfluorododecanoic acid results in decreased phosphorylation of AKT2 protein |
CTD |
PMID:30489073 |
|
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Alb |
albumin |
increases expression decreases expression |
EXP |
perfluorododecanoic acid results in increased expression of ALB protein perfluorododecanoic acid results in decreased expression of ALB protein |
CTD |
PMID:19854247 PMID:26168851 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
decreases expression multiple interactions |
EXP |
perfluorododecanoic acid results in decreased expression of ALDH2 protein PPARA mRNA promotes the reaction [perfluorododecanoic acid results in decreased expression of ALDH2 protein] |
CTD |
PMID:26168851 |
|
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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|
G |
Aldh9a1 |
aldehyde dehydrogenase 9 family, member A1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ALDH9A1 protein |
CTD |
PMID:26168851 |
|
NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
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|
G |
Angptl4 |
angiopoietin-like 4 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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|
G |
Apoa2 |
apolipoprotein A2 |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of APOA2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
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|
G |
Apoa4 |
apolipoprotein A4 |
affects expression |
EXP |
perfluorododecanoic acid affects the expression of APOA4 mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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|
G |
Ar |
androgen receptor |
affects expression |
EXP |
perfluorododecanoic acid affects the expression of AR mRNA |
CTD |
PMID:19397962 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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|
G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of ARHGDIB protein |
CTD |
PMID:19854247 |
|
NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of ATF3 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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|
G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ATP5PD mRNA |
CTD |
PMID:19854247 |
|
NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
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|
G |
Baat |
bile acid CoA:amino acid N-acyltransferase |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of BAAT mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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|
G |
Bdh2 |
3-hydroxybutyrate dehydrogenase 2 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of BDH2 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
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|
G |
Ccnd1 |
cyclin D1 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of CCND1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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|
G |
Cd36 |
CD36 molecule |
increases expression increases uptake |
EXP ISO |
perfluorododecanoic acid results in increased expression of CD36 mRNA CD36 protein results in increased uptake of perfluorododecanoic acid |
CTD |
PMID:23353032 PMID:35380827 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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|
G |
Cdh5 |
cadherin 5 |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of CDH5 protein |
CTD |
PMID:33677611 |
|
NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
|
|
G |
Cops4 |
COP9 signalosome subunit 4 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of COPS4 protein |
CTD |
PMID:26168851 |
|
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
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|
G |
Cops8 |
COP9 signalosome subunit 8 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of COPS8 protein |
CTD |
PMID:19854247 |
|
NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258
|
|
G |
Cox5a |
cytochrome c oxidase subunit 5A |
decreases expression increases expression |
EXP |
perfluorododecanoic acid results in decreased expression of COX5A protein perfluorododecanoic acid results in increased expression of COX5A mRNA |
CTD |
PMID:19854247 |
|
NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
|
|
G |
Cox5b |
cytochrome c oxidase subunit 5B |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of COX5B mRNA |
CTD |
PMID:19854247 |
|
NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
|
|
G |
Cps1 |
carbamoyl-phosphate synthase 1 |
decreases expression multiple interactions |
EXP |
perfluorododecanoic acid results in decreased expression of CPS1 mRNA; perfluorododecanoic acid results in decreased expression of CPS1 protein PPARA mRNA inhibits the reaction [perfluorododecanoic acid results in decreased expression of CPS1 mRNA] |
CTD |
PMID:26168851 |
|
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
|
|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of CPT1A mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
|
|
G |
Crym |
crystallin, mu |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of CRYM protein |
CTD |
PMID:26168851 |
|
NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
|
|
G |
Csk |
C-terminal Src kinase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of CSK mRNA; perfluorododecanoic acid results in decreased expression of CSK protein |
CTD |
PMID:19854247 |
|
NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
|
|
G |
Ctsa |
cathepsin A |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of CTSA protein |
CTD |
PMID:26168851 |
|
NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
|
|
G |
Cuta |
cutA divalent cation tolerance homolog |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of CUTA protein |
CTD |
PMID:19854247 |
|
NCBI chr20:5,022,956...5,024,580
Ensembl chr20:5,022,956...5,024,552
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of CYP11A1 mRNA; perfluorododecanoic acid results in decreased expression of CYP11A1 protein |
CTD |
PMID:17400581 PMID:19397962 PMID:19429406 PMID:30489073 PMID:33774092 |
|
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of CYP17A1 mRNA; perfluorododecanoic acid results in decreased expression of CYP17A1 protein |
CTD |
PMID:17400581 PMID:30489073 PMID:33774092 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of CYP2B10 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of CYP3A4 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
|
|
G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions increases expression |
EXP |
perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of CYP4A1 mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of CYP4A1 mRNA] perfluorododecanoic acid results in increased expression of CYP4A1 mRNA |
CTD |
PMID:26168851 |
|
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
|
|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G |
Ddah1 |
dimethylarginine dimethylaminohydrolase 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of DDAH1 protein |
CTD |
PMID:26168851 |
|
NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of DDIT3 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
|
|
G |
Ddt |
D-dopachrome tautomerase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of DDT protein |
CTD |
PMID:19854247 |
|
NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482
|
|
G |
Dhh |
desert hedgehog signaling molecule |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of DHH mRNA; perfluorododecanoic acid results in decreased expression of DHH protein |
CTD |
PMID:33774092 |
|
NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
|
|
G |
Dlat |
dihydrolipoamide S-acetyltransferase |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of DLAT protein |
CTD |
PMID:26168851 |
|
NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
|
|
G |
Drd2 |
dopamine receptor D2 |
multiple interactions |
ISO |
[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in increased expression of DRD2 mRNA |
CTD |
PMID:34371090 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
|
|
G |
Ech1 |
enoyl-CoA hydratase 1 |
increases expression multiple interactions |
EXP |
perfluorododecanoic acid results in increased expression of ECH1 mRNA; perfluorododecanoic acid results in increased expression of ECH1 protein PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ECH1 mRNA] |
CTD |
PMID:26168851 |
|
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
|
|
G |
Efhd2 |
EF-hand domain family, member D2 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of EFHD2 protein |
CTD |
PMID:19854247 |
|
NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
|
|
G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of EHHADH mRNA |
CTD |
PMID:35337807 |
|
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
|
|
G |
Esr1 |
estrogen receptor 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ESR1 mRNA |
CTD |
PMID:19429406 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
|
|
G |
Esr2 |
estrogen receptor 2 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ESR2 mRNA |
CTD |
PMID:19429406 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
|
|
G |
Ethe1 |
ETHE1, persulfide dioxygenase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of ETHE1 protein |
CTD |
PMID:26168851 |
|
NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052
|
|
G |
Fabp1 |
fatty acid binding protein 1 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of FABP1 mRNA |
CTD |
PMID:23567314 PMID:35337807 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
|
|
G |
Fasn |
fatty acid synthase |
decreases expression affects expression |
EXP ISO |
perfluorododecanoic acid results in decreased expression of FASN mRNA perfluorododecanoic acid affects the expression of FASN mRNA |
CTD |
PMID:23353032 PMID:35337807 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
|
|
G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of FDFT1 mRNA |
CTD |
PMID:22071372 |
|
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
|
|
G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of FHIT protein |
CTD |
PMID:19854247 |
|
NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
|
|
G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression decreases secretion |
EXP |
perfluorododecanoic acid results in decreased expression of FSHB mRNA; perfluorododecanoic acid results in decreased expression of FSHB protein perfluorododecanoic acid results in decreased secretion of FSHB protein |
CTD |
PMID:19397962 PMID:30489073 PMID:33774092 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
|
|
G |
Fshr |
follicle stimulating hormone receptor |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of FSHR mRNA; perfluorododecanoic acid results in decreased expression of FSHR protein |
CTD |
PMID:33774092 |
|
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
|
|
G |
Fth1 |
ferritin heavy chain 1 |
decreases expression increases expression |
EXP |
perfluorododecanoic acid results in decreased expression of FTH1 protein perfluorododecanoic acid results in increased expression of FTH1 mRNA |
CTD |
PMID:19854247 |
|
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
|
|
G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of GADD45B mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
|
|
G |
Gc |
GC, vitamin D binding protein |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of GC protein |
CTD |
PMID:26168851 |
|
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
|
|
G |
Gk |
glycerol kinase |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of GK mRNA |
CTD |
PMID:23567314 |
|
NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
|
|
G |
Glod4 |
glyoxalase domain containing 4 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of GLOD4 protein |
CTD |
PMID:19854247 |
|
NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
|
|
G |
Gmfb |
glia maturation factor, beta |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of GMFB protein |
CTD |
PMID:26168851 |
|
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
|
|
G |
Gmfg |
glia maturation factor, gamma |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of GMFG protein |
CTD |
PMID:19854247 |
|
NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183
|
|
G |
Gnrhr |
gonadotropin releasing hormone receptor |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of GNRHR mRNA |
CTD |
PMID:19397962 |
|
NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
|
|
G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of GPAM mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
|
|
G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of GPD1 protein |
CTD |
PMID:26168851 |
|
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
|
|
G |
Gsk3a |
glycogen synthase kinase 3 alpha |
decreases expression affects response to substance |
EXP |
perfluorododecanoic acid results in decreased expression of GSK3A protein; perfluorododecanoic acid results in decreased expression of GSK3A protein modified form GSK3A protein affects the susceptibility to perfluorododecanoic acid |
CTD |
PMID:23353032 |
|
NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
affects response to substance decreases expression |
EXP |
GSK3B protein affects the susceptibility to perfluorododecanoic acid perfluorododecanoic acid results in decreased expression of GSK3B protein; perfluorododecanoic acid results in decreased expression of GSK3B protein modified form |
CTD |
PMID:23353032 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of GSTA1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
|
|
G |
Haao |
3-hydroxyanthranilate 3,4-dioxygenase |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HAAO protein |
CTD |
PMID:26168851 |
|
NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
|
|
G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
affects expression increases expression multiple interactions |
ISO EXP |
perfluorododecanoic acid affects the expression of HADHA mRNA perfluorododecanoic acid results in increased expression of HADHA mRNA; perfluorododecanoic acid results in increased expression of HADHA protein PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of HADHA mRNA] |
CTD |
PMID:22071372 PMID:23567314 PMID:26168851 |
|
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
|
|
G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HADHB mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
|
|
G |
Hhex |
hematopoietically expressed homeobox |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HHEX mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
|
|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of HMGCS1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
|
|
G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of HMGCS2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of HMOX1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
|
|
G |
Hpx |
hemopexin |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HPX protein |
CTD |
PMID:26168851 |
|
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
|
|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of HSD11B1 mRNA; perfluorododecanoic acid results in decreased expression of HSD11B1 protein |
CTD |
PMID:30489073 PMID:33774092 |
|
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
|
|
G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity |
ISO |
perfluorododecanoic acid results in decreased activity of HSD11B2 protein |
CTD |
PMID:36878351 |
|
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
|
|
G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of HSD17B1 mRNA |
CTD |
PMID:19429406 |
|
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
|
|
G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
affects expression |
EXP |
perfluorododecanoic acid affects the expression of HSD17B2 mRNA |
CTD |
PMID:33774092 |
|
NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
|
|
G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
decreases expression affects expression |
EXP |
perfluorododecanoic acid results in decreased expression of HSD17B3 mRNA perfluorododecanoic acid affects the expression of HSD17B3 protein |
CTD |
PMID:17400581 PMID:33774092 |
|
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
|
|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases expression affects expression decreases activity |
EXP ISO |
perfluorododecanoic acid results in decreased expression of HSD3B1 mRNA; perfluorododecanoic acid results in decreased expression of HSD3B1 protein perfluorododecanoic acid affects the expression of HSD3B1 mRNA; perfluorododecanoic acid affects the expression of HSD3B1 protein perfluorododecanoic acid results in decreased activity of HSD3B1 protein |
CTD |
PMID:17400581 PMID:33774092 PMID:36122607 |
|
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
affects expression |
EXP |
perfluorododecanoic acid affects the expression of HSPA5 protein |
CTD |
PMID:26168851 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HSPA8 protein |
CTD |
PMID:26168851 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HSPA9 protein |
CTD |
PMID:26168851 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of HSPD1 protein |
CTD |
PMID:26168851 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
|
|
G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IDH3A protein |
CTD |
PMID:26168851 |
|
NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
|
|
G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of IDO1 protein |
CTD |
PMID:19854247 |
|
NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
|
|
G |
Ift20 |
intraflagellar transport 20 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IFT20 protein |
CTD |
PMID:19854247 |
|
NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124
|
|
G |
Igf1 |
insulin-like growth factor 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IGF1 mRNA |
CTD |
PMID:19397962 |
|
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
|
|
G |
Igf1r |
insulin-like growth factor 1 receptor |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IGF1R mRNA |
CTD |
PMID:19397962 |
|
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
|
|
G |
Il1a |
interleukin 1 alpha |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IL1A mRNA |
CTD |
PMID:19397962 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
|
|
G |
Impa1 |
inositol monophosphatase 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IMPA1 protein |
CTD |
PMID:19854247 |
|
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
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G |
Irs1 |
insulin receptor substrate 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IRS1 protein modified form |
CTD |
PMID:23353032 |
|
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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G |
Itga1 |
integrin subunit alpha 1 |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of ITGA1 protein |
CTD |
PMID:33677611 |
|
NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
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G |
Itpa |
inosine triphosphatase |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of ITPA protein |
CTD |
PMID:26168851 |
|
NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249
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G |
Ivd |
isovaleryl-CoA dehydrogenase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of IVD protein |
CTD |
PMID:26168851 |
|
NCBI chr 3:105,851,710...105,872,144
Ensembl chr 3:105,851,683...105,872,575
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G |
Krt10 |
keratin 10 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of KRT10 protein |
CTD |
PMID:19854247 |
|
NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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G |
Krt14 |
keratin 14 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of KRT14 protein |
CTD |
PMID:19854247 |
|
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
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G |
Krt16 |
keratin 16 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of KRT16 protein |
CTD |
PMID:19854247 |
|
NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
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G |
Krt8 |
keratin 8 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of KRT8 protein |
CTD |
PMID:26168851 |
|
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Lhb |
luteinizing hormone subunit beta |
decreases expression decreases secretion |
EXP |
perfluorododecanoic acid results in decreased expression of LHB mRNA; perfluorododecanoic acid results in decreased expression of LHB protein perfluorododecanoic acid results in decreased secretion of LHB protein |
CTD |
PMID:17400581 PMID:19397962 PMID:30489073 PMID:33774092 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
decreases expression affects expression |
EXP |
perfluorododecanoic acid results in decreased expression of LHCGR mRNA; perfluorododecanoic acid results in decreased expression of LHCGR protein perfluorododecanoic acid affects the expression of LHCGR mRNA; perfluorododecanoic acid affects the expression of LHCGR protein |
CTD |
PMID:19429406 PMID:30489073 PMID:33774092 |
|
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Lhpp |
phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of LHPP protein |
CTD |
PMID:26168851 |
|
NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
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G |
Mbl2 |
mannose binding lectin 2 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of MBL2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:228,016,439...228,024,736
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G |
Mdh1 |
malate dehydrogenase 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of MDH1 protein |
CTD |
PMID:26168851 |
|
NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
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G |
Mttp |
microsomal triglyceride transfer protein |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of MTTP mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Mug2 |
murinoglobulin 2 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PZP protein |
CTD |
PMID:26168851 |
|
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
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G |
Ndufv2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of NDUFV2 protein |
CTD |
PMID:26168851 |
|
NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of NOS2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity |
ISO |
perfluorododecanoic acid results in increased activity of NR1I2 protein |
CTD |
PMID:28115241 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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|
G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of NR1I3 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Ntan1 |
N-terminal asparagine amidase |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of NTAN1 protein |
CTD |
PMID:19854247 |
|
NCBI chr10:2,111,090...2,126,119
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|
G |
P4hb |
prolyl 4-hydroxylase subunit beta |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of P4HB protein |
CTD |
PMID:26168851 |
|
NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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G |
Park7 |
Parkinsonism associated deglycase |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PARK7 protein |
CTD |
PMID:19854247 |
|
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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G |
Pax8 |
paired box 8 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of PAX8 mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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G |
Pbld1 |
phenazine biosynthesis-like protein domain containing 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PBLD1 protein |
CTD |
PMID:26168851 |
|
NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of PCK2 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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G |
Pdhb |
pyruvate dehydrogenase E1 subunit beta |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of PDHB protein |
CTD |
PMID:26168851 |
|
NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
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G |
Pdia6 |
protein disulfide isomerase family A, member 6 |
affects expression |
EXP |
perfluorododecanoic acid affects the expression of PDIA6 protein |
CTD |
PMID:26168851 |
|
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of PDK4 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdpk1 |
3-phosphoinositide dependent protein kinase-1 |
decreases activity decreases expression |
EXP |
perfluorododecanoic acid results in decreased activity of PDPK1 protein perfluorododecanoic acid results in decreased expression of PDPK1 protein; perfluorododecanoic acid results in decreased expression of PDPK1 protein modified form |
CTD |
PMID:23353032 |
|
NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
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G |
Pebp1 |
phosphatidylethanolamine binding protein 1 |
decreases expression increases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PEBP1 protein perfluorododecanoic acid results in increased expression of PEBP1 mRNA |
CTD |
PMID:19854247 |
|
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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G |
Phb1 |
prohibitin 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of PHB1 protein |
CTD |
PMID:26168851 |
|
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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G |
Pitpna |
phosphatidylinositol transfer protein, alpha |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PITPNA protein |
CTD |
PMID:19854247 |
|
NCBI chr10:60,430,712...60,473,564
Ensembl chr10:60,430,748...60,471,342
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G |
Plin2 |
perilipin 2 |
increases expression affects expression |
ISO |
perfluorododecanoic acid results in increased expression of PLIN2 mRNA perfluorododecanoic acid affects the expression of PLIN2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of POR mRNA |
CTD |
PMID:23567314 |
|
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases activity multiple interactions increases expression increases response to substance |
ISO EXP |
perfluorododecanoic acid results in increased activity of PPARA protein perfluorododecanoic acid inhibits the reaction [GW 6471 results in decreased expression of PPARA mRNA]; perfluorododecanoic acid inhibits the reaction [pirinixic acid results in increased expression of PPARA mRNA]; PPARA mRNA inhibits the reaction [perfluorododecanoic acid results in decreased expression of CPS1 mRNA]; PPARA mRNA inhibits the reaction [perfluorododecanoic acid results in increased abundance of Reactive Oxygen Species]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in decreased expression of ALDH2 protein]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT1 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ACOT2 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of ECH1 mRNA]; PPARA mRNA promotes the reaction [perfluorododecanoic acid results in increased expression of HADHA mRNA] perfluorododecanoic acid results in increased expression of PPARA mRNA; perfluorododecanoic acid results in increased expression of PPARA protein PPARA mRNA results in increased susceptibility to perfluorododecanoic acid |
CTD |
PMID:22107727 PMID:26168851 PMID:28857218 PMID:35337807 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of PPARD mRNA |
CTD |
PMID:23567314 |
|
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases activity increases expression |
ISO |
perfluorododecanoic acid results in increased activity of PPARG protein perfluorododecanoic acid results in increased expression of PPARG mRNA |
CTD |
PMID:23391484 PMID:24998974 PMID:35337807 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PPARGC1A protein |
CTD |
PMID:30489073 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prdx2 |
peroxiredoxin 2 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PRDX2 protein |
CTD |
PMID:26168851 |
|
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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G |
Prdx4 |
peroxiredoxin 4 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PRDX4 protein |
CTD |
PMID:26168851 |
|
NCBI chr X:40,026,762...40,044,066
Ensembl chr X:40,026,651...40,044,066
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G |
Psmf1 |
proteasome inhibitor subunit 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of PSMF1 protein |
CTD |
PMID:19854247 |
|
NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546
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|
G |
Ptpn11 |
protein tyrosine phosphatase, non-receptor type 11 |
multiple interactions |
ISO |
perfluorododecanoic acid binds to and results in decreased activity of PTPN11 protein |
CTD |
PMID:27572461 |
|
NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
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|
G |
Ranbp1 |
RAN binding protein 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of RANBP1 protein |
CTD |
PMID:19854247 |
|
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
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G |
Rbp4 |
retinol binding protein 4 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of RBP4 protein |
CTD |
PMID:26168851 |
|
NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
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G |
Rgn |
regucalcin |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of RGN protein |
CTD |
PMID:26168851 |
|
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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G |
Scarb1 |
scavenger receptor class B, member 1 |
decreases expression affects expression |
EXP |
perfluorododecanoic acid results in decreased expression of SCARB1 mRNA; perfluorododecanoic acid results in decreased expression of SCARB1 protein perfluorododecanoic acid affects the expression of SCARB1 mRNA; perfluorododecanoic acid affects the expression of SCARB1 protein |
CTD |
PMID:17400581 PMID:30489073 PMID:33774092 |
|
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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G |
Scd |
stearoyl-CoA desaturase |
decreases expression increases expression |
ISO EXP |
perfluorododecanoic acid results in decreased expression of SCD mRNA perfluorododecanoic acid results in increased expression of SCD1 mRNA |
CTD |
PMID:23353032 PMID:23567314 PMID:35337807 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Serpind1 |
serpin family D member 1 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of SERPIND1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
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G |
Serpinf2 |
serpin family F member 2 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of SERPINF2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
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G |
Sirt1 |
sirtuin 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of SIRT1 protein |
CTD |
PMID:30489073 |
|
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Slc25a20 |
solute carrier family 25 member 20 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of SLC25A20 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc27a1 |
solute carrier family 27 member 1 |
increases expression |
ISO |
perfluorododecanoic acid results in increased expression of SLC27A1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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G |
Sod1 |
superoxide dismutase 1 |
decreases expression affects expression |
EXP ISO |
perfluorododecanoic acid results in decreased expression of SOD1 mRNA perfluorododecanoic acid affects the expression of SOD1 mRNA |
CTD |
PMID:19854247 PMID:35337807 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sox9 |
SRY-box transcription factor 9 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of SOX9 mRNA; perfluorododecanoic acid results in decreased expression of SOX9 protein |
CTD |
PMID:33774092 |
|
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
affects expression |
EXP |
perfluorododecanoic acid affects the expression of SRD5A1 mRNA |
CTD |
PMID:33774092 |
|
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
EXP ISO |
perfluorododecanoic acid results in increased expression of SREBF1 mRNA |
CTD |
PMID:23353032 PMID:35337807 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions decreases expression affects expression |
ISO EXP |
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein]]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR mRNA]; perfluorododecanoic acid inhibits the reaction [Cyclic AMP results in increased expression of STAR protein] perfluorododecanoic acid results in decreased expression of STAR mRNA; perfluorododecanoic acid results in decreased expression of STAR protein perfluorododecanoic acid affects the expression of STAR mRNA; perfluorododecanoic acid affects the expression of STAR protein |
CTD |
PMID:17400581 PMID:19397962 PMID:19429406 PMID:20100736 PMID:30489073 PMID:33774092 More...
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|
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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G |
Stmn1 |
stathmin 1 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of STMN1 protein |
CTD |
PMID:19854247 |
|
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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G |
Suclg2 |
succinate-CoA ligase GDP-forming subunit beta |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of SUCLG2 protein |
CTD |
PMID:26168851 |
|
NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
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|
G |
Sult1c3 |
sulfotransferase family 1C member 3 |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of SULT1C3 protein |
CTD |
PMID:26168851 |
|
NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
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|
G |
Sult2a1 |
sulfotransferase family 2A member 1 |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of SULT2A1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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G |
Suox |
sulfite oxidase |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of SUOX protein |
CTD |
PMID:26168851 |
|
NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA |
CTD |
PMID:34371090 |
|
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Thra |
thyroid hormone receptor alpha |
affects binding |
ISO |
perfluorododecanoic acid binds to THRA protein |
CTD |
PMID:24819616 |
|
NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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|
G |
Tpm1 |
tropomyosin 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of TPM1 protein |
CTD |
PMID:26168851 |
|
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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|
G |
Trap1 |
TNF receptor-associated protein 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of TRAP1 protein |
CTD |
PMID:26168851 |
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NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
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G |
Ttr |
transthyretin |
multiple interactions |
ISO |
perfluorododecanoic acid affects the reaction [Thyroxine binds to TTR protein] |
CTD |
PMID:27528273 |
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NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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G |
Txnip |
thioredoxin interacting protein |
affects expression |
ISO |
perfluorododecanoic acid affects the expression of TXNIP mRNA |
CTD |
PMID:23567314 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Ube2n |
ubiquitin-conjugating enzyme E2N |
decreases expression |
EXP |
perfluorododecanoic acid results in decreased expression of UBE2N protein |
CTD |
PMID:19854247 |
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NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
decreases expression |
ISO |
perfluorododecanoic acid results in decreased expression of UGT1A1 mRNA |
CTD |
PMID:35337807 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Uqcrc1 |
ubiquinol-cytochrome c reductase core protein 1 |
increases expression |
EXP |
perfluorododecanoic acid results in increased expression of UQCRC1 protein |
CTD |
PMID:26168851 |
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NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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G |
Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
decreases expression increases expression |
EXP |
perfluorododecanoic acid results in decreased expression of UQCRH protein perfluorododecanoic acid results in increased expression of UQCRH mRNA |
CTD |
PMID:19854247 |
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NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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G |
Ywhae |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
decreases expression increases expression |
EXP |
perfluorododecanoic acid results in decreased expression of YWHAE protein perfluorododecanoic acid results in increased expression of YWHAE mRNA |
CTD |
PMID:19854247 |
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NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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