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Creb1 |
cAMP responsive element binding protein 1 |
affects expression |
ISO |
4-Aminobenzoic Acid affects the expression of CREB1 mRNA |
CTD |
PMID:20385217 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Il2 |
interleukin 2 |
increases expression |
ISO |
4-Aminobenzoic Acid results in increased expression of IL2 protein |
CTD |
PMID:22381623 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Nat1 |
N-acetyltransferase 1 |
multiple interactions increases metabolic processing affects acetylation increases acetylation |
ISO |
Dehydroepiandrosterone Sulfate inhibits the reaction [NAT1 protein results in increased acetylation of 4-Aminobenzoic Acid]; Dehydroepiandrosterone Sulfate promotes the reaction [NAT1 protein results in increased acetylation of 4-Aminobenzoic Acid]; Pentachlorophenol inhibits the reaction [NAT1 protein results in increased acetylation of 4-Aminobenzoic Acid] NAT1 protein results in increased metabolism of 4-Aminobenzoic Acid NAT1 protein affects the acetylation of 4-Aminobenzoic Acid |
CTD |
PMID:11470991 PMID:15627487 PMID:15880531 PMID:16003948 PMID:23958860 PMID:29043425 PMID:30358977 More...
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NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
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Nat2 |
N-acetyltransferase 2 |
increases acetylation multiple interactions |
ISO EXP |
NAT2 protein results in increased acetylation of 4-Aminobenzoic Acid 4-biphenylamine inhibits the reaction [NAT2 protein results in increased acetylation of 4-Aminobenzoic Acid] |
CTD |
PMID:15627487 PMID:18842621 |
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NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
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Nfkb1 |
nuclear factor kappa B subunit 1 |
affects expression |
ISO |
4-Aminobenzoic Acid affects the expression of NFKB1 mRNA |
CTD |
PMID:20385217 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Slc22a7 |
solute carrier family 22 member 7 |
multiple interactions |
ISO EXP |
4-Aminobenzoic Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid] |
CTD |
PMID:22981274 |
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NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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Tnf |
tumor necrosis factor |
affects expression |
ISO |
4-Aminobenzoic Acid affects the expression of TNF mRNA |
CTD |
PMID:20385217 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Ar |
androgen receptor |
affects binding |
EXP |
butamben binds to AR protein |
CTD |
PMID:14565775 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Med1 |
mediator complex subunit 1 |
multiple interactions |
ISO |
butamben promotes the reaction [NR1I2.L protein binds to MED1 protein]; butamben promotes the reaction [NR1I2.S protein binds to MED1 protein] |
CTD |
PMID:12198127 |
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NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions |
ISO |
butamben promotes the reaction [NR1I2.L protein binds to NCOA1 protein]; butamben promotes the reaction [NR1I2.S protein binds to NCOA1 protein] |
CTD |
PMID:12198127 |
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NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
butamben promotes the reaction [NR1I2.L protein binds to NCOA2 protein] |
CTD |
PMID:12198127 |
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NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Ncoa3 |
nuclear receptor coactivator 3 |
multiple interactions |
ISO |
butamben promotes the reaction [NR1I2.L protein binds to NCOA3 protein] |
CTD |
PMID:12198127 |
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NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Procaine results in increased phosphorylation of AKT1 protein HRH1 protein affects the reaction [Procaine results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:32061592 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases expression |
ISO |
Procaine results in increased expression of ALPL mRNA |
CTD |
PMID:22083529 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Calca |
calcitonin-related polypeptide alpha |
increases secretion |
ISO |
Procaine results in increased secretion of CALCA protein |
CTD |
PMID:18172555 |
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NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Casp12 |
caspase 12 |
multiple interactions |
ISO |
Procaine inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] |
CTD |
PMID:20079824 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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Cdh5 |
cadherin 5 |
decreases expression multiple interactions |
ISO |
Procaine results in decreased expression of CDH5 protein HRH1 protein affects the reaction [Procaine results in decreased expression of CDH5 protein] |
CTD |
PMID:32061592 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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Ces2h |
carboxylesterase 2H |
increases hydrolysis |
ISO |
CES2 protein results in increased hydrolysis of Procaine |
CTD |
PMID:9300133 PMID:15475733 |
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NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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Esr1 |
estrogen receptor 1 |
increases expression |
ISO |
Procaine results in increased expression of ESR1 mRNA |
CTD |
PMID:22083529 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Hrh1 |
histamine receptor H 1 |
multiple interactions affects binding |
ISO |
[HRH1 protein binds to Procaine] which results in increased import of Calcium; HRH1 protein affects the reaction [Procaine results in decreased expression of CDH5 protein]; HRH1 protein affects the reaction [Procaine results in increased phosphorylation of AKT1 protein]; HRH1 protein affects the reaction [Procaine results in increased phosphorylation of ITPR1 protein]; HRH1 protein affects the reaction [Procaine results in increased phosphorylation of MAPK1 protein]; HRH1 protein affects the reaction [Procaine results in increased phosphorylation of MAPK3 protein]; HRH1 protein affects the reaction [Procaine results in increased phosphorylation of PLCG1 protein]; HRH1 protein affects the reaction [Procaine results in increased transport of fluorescein isothiocyanate bovine serum albumin] |
CTD |
PMID:32061592 |
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NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
increases phosphorylation multiple interactions |
ISO |
Procaine results in increased phosphorylation of ITPR1 protein HRH1 protein affects the reaction [Procaine results in increased phosphorylation of ITPR1 protein] |
CTD |
PMID:32061592 |
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NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Procaine results in increased phosphorylation of MAPK1 protein HRH1 protein affects the reaction [Procaine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:32061592 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Procaine results in increased phosphorylation of MAPK3 protein HRH1 protein affects the reaction [Procaine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:32061592 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity |
ISO |
Procaine results in increased activity of NR1I2 protein |
CTD |
PMID:25455453 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Plcg1 |
phospholipase C, gamma 1 |
increases phosphorylation multiple interactions |
ISO |
Procaine results in increased phosphorylation of PLCG1 protein HRH1 protein affects the reaction [Procaine results in increased phosphorylation of PLCG1 protein] |
CTD |
PMID:32061592 |
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NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
increases activity |
EXP |
Procaine results in increased activity of TRPV1 protein |
CTD |
PMID:18172555 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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