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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:gamma-aminobutyrate
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Accession:CHEBI:30566 term browser browse the term
Definition:An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid.
Synonyms:exact_synonym: 4-aminobutanoate
 related_synonym: 4-Amino-butyrat;   4-Aminobutylate;   4-aminobutanoic acid ion (1-);   4-aminobutyrate;   Formula=C4H8NO2;   InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1;   InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-M;   SMILES=NCCCC([O-])=O;   gamma-aminobutanoate;   gamma-aminobutyrate anion
 alt_id: CHEBI:11961;   CHEBI:20317
 xref: Beilstein:3536873;   Gmelin:559138;   KEGG:C00334;   PMID:12509893;   Reaxys:3536873
 cyclic_relationship: is_conjugate_base_of CHEBI:16865



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4-(trimethylammonio)butanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO [BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine CTD PMID:21439360 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            butyrate 89
              gamma-aminobutyrate 2
                4-(trimethylammonio)butanoate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic ion 9167
                              organic anion 3089
                                carboxylic acid anion 2437
                                  monocarboxylic acid anion 1552
                                    fatty acid anion 108
                                      short-chain fatty acid anion 101
                                        fatty acid anion 4:0 89
                                          butyrate 89
                                            gamma-aminobutyrate 2
                                              4-(trimethylammonio)butanoate 2
paths to the root