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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:30566 term browser browse the term
Definition:An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid.
Synonyms:exact_synonym: 4-aminobutanoate
 related_synonym: 4-Amino-butyrat;   4-Aminobutylate;   4-aminobutanoic acid ion (1-);   4-aminobutyrate;   Formula=C4H8NO2;   InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1;   InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-M;   SMILES=NCCCC([O-])=O;   gamma-aminobutanoate;   gamma-aminobutyrate anion
 alt_id: CHEBI:11961;   CHEBI:20317
 xref: Beilstein:3536873;   Gmelin:559138;   KEGG:C00334;   PMID:12509893;   Reaxys:3536873
 cyclic_relationship: is_conjugate_base_of CHEBI:16865

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4-(trimethylammonio)butanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO [BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine CTD PMID:21439360 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        biochemical role 19328
          metabolite 19308
            butyrate 81
              gamma-aminobutyrate 2
                4-(trimethylammonio)butanoate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic ion 8402
                              organic anion 3020
                                carboxylic acid anion 2392
                                  monocarboxylic acid anion 1491
                                    fatty acid anion 100
                                      short-chain fatty acid anion 93
                                        fatty acid anion 4:0 81
                                          butyrate 81
                                            gamma-aminobutyrate 2
                                              4-(trimethylammonio)butanoate 2
paths to the root