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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beryllium(2+)
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Accession:CHEBI:30502 term browser browse the term
Definition:A beryllium cation that has formula Be.
Synonyms:exact_synonym: beryllium(2+) ion;   beryllium(II) cation
 related_synonym: Be(2+);   Formula=Be;   InChI=1S/Be/q+2;   InChIKey=PWOSZCQLSAMRQW-UHFFFAOYSA-N;   SMILES=[Be++]
 xref: CAS:22537-20-8;   Gmelin:6849
 xref_mesh: MESH:D001608



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beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL4 acyl-CoA synthetase long chain family member 4 increases expression
multiple interactions
EXP beryllium sulfate results in increased expression of ACSL4 mRNA
[sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]
CTD PMID:36843388 NCBI chr  X:109,641,335...109,733,257
Ensembl chr  X:109,624,244...109,733,403
JBrowse link
G ACTA2 actin alpha 2, smooth muscle increases expression EXP beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G AMOT angiomotin decreases expression EXP beryllium sulfate results in decreased expression of AMOT mRNA CTD PMID:35679967 NCBI chr  X:112,774,877...112,840,831
Ensembl chr  X:112,774,503...112,840,831
JBrowse link
G ANXA5 annexin A5 increases expression EXP beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G ARHGAP26 Rho GTPase activating protein 26 increases expression
decreases expression
EXP beryllium sulfate results in increased expression of ARHGAP26 mRNA
beryllium sulfate results in decreased expression of ARHGAP26 mRNA
CTD PMID:35679967 NCBI chr 5:142,770,377...143,229,011
Ensembl chr 5:142,770,377...143,229,011
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
EXP beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases secretion EXP beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression EXP beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCNT1 cyclin T1 increases expression EXP beryllium sulfate results in increased expression of CCNT1 mRNA CTD PMID:35679967 NCBI chr12:48,688,458...48,716,707
Ensembl chr12:48,688,458...48,716,998
JBrowse link
G CD44 CD44 molecule (IN blood group) increases expression EXP beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD86 CD86 molecule increases expression EXP beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
EXP beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A increases expression EXP beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRYAA crystallin alpha A decreases expression EXP beryllium sulfate results in decreased expression of CRYAA mRNA CTD PMID:35679967 NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805
JBrowse link
G CTSL cathepsin L increases expression EXP beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
JBrowse link
G CTSV cathepsin V increases expression EXP beryllium sulfate results in increased expression of CTSV mRNA CTD PMID:16314022 NCBI chr 9:97,029,677...97,039,643
Ensembl chr 9:97,029,677...97,156,556
JBrowse link
G CUL9 cullin 9 increases expression
decreases expression
EXP beryllium sulfate results in increased expression of CUL9 mRNA
beryllium sulfate results in decreased expression of CUL9 mRNA
CTD PMID:35679967 NCBI chr 6:43,182,196...43,224,587
Ensembl chr 6:43,182,184...43,224,587
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases secretion EXP beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 increases expression EXP beryllium sulfate results in increased expression of CXCL3 mRNA CTD PMID:16314022 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
JBrowse link
G DDHD2 DDHD domain containing 2 increases expression EXP beryllium sulfate results in increased expression of DDHD2 mRNA CTD PMID:35679967 NCBI chr 8:38,231,585...38,273,647
Ensembl chr 8:38,225,218...38,275,558
JBrowse link
G EGR2 early growth response 2 increases expression EXP beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FTH1 ferritin heavy chain 1 multiple interactions
decreases expression
EXP [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 protein]
beryllium sulfate results in decreased expression of FTH1 mRNA; beryllium sulfate results in decreased expression of FTH1 protein
CTD PMID:36843388 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
JBrowse link
G GPX4 glutathione peroxidase 4 decreases expression
multiple interactions
EXP beryllium sulfate results in decreased expression of GPX4 mRNA
[sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]
CTD PMID:36843388 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
JBrowse link
G HLA-A major histocompatibility complex, class I, A increases expression EXP beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
JBrowse link
G HLA-C major histocompatibility complex, class I, C increases expression EXP beryllium sulfate results in increased expression of HLA-C mRNA CTD PMID:16314022 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 affects binding EXP beryllium sulfate binds to HLA-DPB1 protein CTD PMID:11423174 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) increases response to substance EXP HLA-DPB2 protein mutant form results in increased susceptibility to beryllium sulfate CTD PMID:16272364 NCBI chr 6:33,112,516...33,129,113
Ensembl chr 6:33,112,516...33,129,084
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 increases response to substance
increases expression
EXP HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
beryllium sulfate results in increased expression of HLA-DRB1 mRNA
CTD PMID:16272364 PMID:16314022 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
EXP 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma increases expression
multiple interactions
EXP
ISO
beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 PMID:20974702 PMID:33197057 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 increases expression EXP beryllium sulfate results in increased expression of IL10 protein CTD PMID:33197057 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL18 interleukin 18 increases expression EXP beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL2 interleukin 2 increases expression ISO beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL5 interleukin 5 increases expression ISO beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 increases expression ISO beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGB3 integrin subunit beta 3 increases expression EXP beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711 PMID:11568973 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G KRT4 keratin 4 decreases expression EXP beryllium sulfate results in decreased expression of KRT4 mRNA CTD PMID:35679967 NCBI chr12:52,806,549...52,814,116
Ensembl chr12:52,806,549...52,814,116
JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 increases expression EXP beryllium sulfate results in increased expression of MIR7 mRNA CTD PMID:33197057 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022
JBrowse link
G LINC00472 long intergenic non-protein coding RNA 472 increases expression
decreases expression
EXP beryllium sulfate results in increased expression of LINC00472 mRNA
beryllium sulfate results in decreased expression of LINC00472 mRNA
CTD PMID:35679967 NCBI chr 6:71,407,864...71,420,745
Ensembl chr 6:71,187,161...71,420,745
JBrowse link
G LINC02108 long intergenic non-protein coding RNA 2108 decreases expression EXP beryllium sulfate results in decreased expression of LINC02108 mRNA CTD PMID:35679967 NCBI chr 5:58,541,567...58,558,243
Ensembl chr 5:58,541,567...58,558,243
JBrowse link
G MFSD14B major facilitator superfamily domain containing 14B decreases expression EXP beryllium sulfate results in decreased expression of MFSD14B mRNA CTD PMID:35679967 NCBI chr 9:94,374,417...94,461,042
Ensembl chr 9:94,374,569...94,461,042
JBrowse link
G MIR1226 microRNA 1226 increases expression EXP beryllium sulfate results in increased expression of MIR1226 mRNA CTD PMID:33197057 NCBI chr 3:47,849,555...47,849,629
Ensembl chr 3:47,849,555...47,849,629
JBrowse link
G MIR1306 microRNA 1306 increases expression EXP beryllium sulfate results in increased expression of MIR1306 mRNA CTD PMID:33197057 NCBI chr22:20,086,058...20,086,142
Ensembl chr22:20,086,058...20,086,142
JBrowse link
G MIR1322 microRNA 1322 increases expression EXP beryllium sulfate results in increased expression of MIR1322 mRNA CTD PMID:33197057 NCBI chr 8:10,825,373...10,825,443
Ensembl chr 8:10,825,373...10,825,443
JBrowse link
G MIR150 microRNA 150 increases expression EXP beryllium sulfate results in increased expression of MIR150 mRNA CTD PMID:33197057 NCBI chr19:49,500,785...49,500,868
Ensembl chr19:49,500,785...49,500,868
JBrowse link
G MIR193B microRNA 193b increases expression EXP beryllium sulfate results in increased expression of MIR193B mRNA CTD PMID:33197057 NCBI chr16:14,303,967...14,304,049
Ensembl chr16:14,303,967...14,304,049
JBrowse link
G MIR23B microRNA 23b decreases expression EXP beryllium sulfate results in decreased expression of MIR23B mRNA CTD PMID:33197057 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304
JBrowse link
G MIR3182 microRNA 3182 increases expression EXP beryllium sulfate results in increased expression of MIR3182 mRNA CTD PMID:33197057 NCBI chr16:83,508,346...83,508,408
Ensembl chr16:83,508,346...83,508,408
JBrowse link
G MIR3200 microRNA 3200 increases expression EXP beryllium sulfate results in increased expression of MIR3200 mRNA CTD PMID:33197057 NCBI chr22:30,731,557...30,731,641
Ensembl chr22:30,731,557...30,731,641
JBrowse link
G MIR324 microRNA 324 increases expression EXP beryllium sulfate results in increased expression of MIR324 mRNA CTD PMID:33197057 NCBI chr17:7,223,297...7,223,379
Ensembl chr17:7,223,297...7,223,379
JBrowse link
G MIR3529 microRNA 3529 increases expression EXP beryllium sulfate results in increased expression of MIR3529 mRNA CTD PMID:33197057 NCBI chr15:88,611,847...88,611,924
Ensembl chr15:88,611,847...88,611,924
JBrowse link
G MIR363 microRNA 363 increases expression EXP beryllium sulfate results in increased expression of MIR363 mRNA CTD PMID:33197057 NCBI chr  X:134,169,378...134,169,452
Ensembl chr  X:134,169,378...134,169,452
JBrowse link
G MIR369 microRNA 369 decreases expression EXP beryllium sulfate results in decreased expression of MIR369 mRNA CTD PMID:33197057 NCBI chr14:101,065,598...101,065,667
Ensembl chr14:101,065,598...101,065,667
JBrowse link
G MIR3911 microRNA 3911 increases expression EXP beryllium sulfate results in increased expression of MIR3911 mRNA CTD PMID:33197057 NCBI chr 9:127,690,687...127,690,795
Ensembl chr 9:127,690,687...127,690,795
JBrowse link
G MIR3940 microRNA 3940 decreases expression EXP beryllium sulfate results in decreased expression of MIR3940 mRNA CTD PMID:33197057 NCBI chr19:6,416,410...6,416,511
Ensembl chr19:6,416,410...6,416,511
JBrowse link
G MIR4482 microRNA 4482 increases expression EXP beryllium sulfate results in increased expression of MIR4482 mRNA CTD PMID:33197057 NCBI chr10:104,268,336...104,268,405
Ensembl chr10:104,268,336...104,268,405
JBrowse link
G MIR4485 microRNA 4485 increases expression EXP beryllium sulfate results in increased expression of MIR4485 mRNA CTD PMID:33197057 NCBI chr11:10,508,270...10,508,326
Ensembl chr11:10,508,270...10,508,326
JBrowse link
G MIR4511 microRNA 4511 decreases expression EXP beryllium sulfate results in decreased expression of MIR4511 mRNA CTD PMID:33197057 NCBI chr15:65,719,246...65,719,332
Ensembl chr15:65,719,246...65,719,332
JBrowse link
G MIR484 microRNA 484 decreases expression EXP beryllium sulfate results in decreased expression of MIR484 mRNA CTD PMID:33197057 NCBI chr16:15,643,294...15,643,372
Ensembl chr16:15,643,294...15,643,372
JBrowse link
G MIR504 microRNA 504 increases expression EXP beryllium sulfate results in increased expression of MIR504 mRNA CTD PMID:33197057 NCBI chr  X:138,667,711...138,667,793
Ensembl chr  X:138,667,711...138,667,793
JBrowse link
G MIR5582 microRNA 5582 increases expression EXP beryllium sulfate results in increased expression of MIR5582 mRNA CTD PMID:33197057 NCBI chr11:46,753,125...46,753,192
Ensembl chr11:46,753,125...46,753,192
JBrowse link
G MIR573 microRNA 573 increases expression EXP beryllium sulfate results in increased expression of MIR573 mRNA CTD PMID:33197057 NCBI chr 4:24,520,192...24,520,290
Ensembl chr 4:24,520,192...24,520,290
JBrowse link
G MIR642A microRNA 642a decreases expression EXP beryllium sulfate results in decreased expression of MIR642 mRNA CTD PMID:33197057 NCBI chr19:45,674,928...45,675,024
Ensembl chr19:45,674,928...45,675,024
JBrowse link
G MIR663B microRNA 663b decreases expression EXP beryllium sulfate results in decreased expression of MIR663B mRNA CTD PMID:33197057 NCBI chr 2:132,256,966...132,257,080
Ensembl chr 2:132,256,966...132,257,080
JBrowse link
G MIR877 microRNA 877 increases expression EXP beryllium sulfate results in increased expression of MIR877 mRNA CTD PMID:33197057 NCBI chr 6:30,584,332...30,584,417
Ensembl chr 6:30,584,332...30,584,417
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NCOA4 nuclear receptor coactivator 4 multiple interactions
increases expression
EXP [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of FTH1 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of GPX4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of ACSL4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of NCOA4 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of NCOA4 protein]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]
beryllium sulfate results in increased expression of NCOA4 mRNA; beryllium sulfate results in increased expression of NCOA4 protein
CTD PMID:36843388 NCBI chr10:46,005,088...46,030,623
Ensembl chr10:46,005,088...46,030,623
JBrowse link
G NEDD8 NEDD8 ubiquitin like modifier increases expression EXP beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr14:24,216,857...24,232,367
Ensembl chr14:24,216,857...24,232,367
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression EXP beryllium sulfate results in increased expression of NOS2 protein CTD PMID:33197057 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOVA1 NOVA alternative splicing regulator 1 increases expression EXP beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr14:26,443,090...26,598,033
Ensembl chr14:26,443,090...26,598,033
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 decreases expression EXP beryllium sulfate results in decreased expression of PDPK1 mRNA CTD PMID:35679967 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188
JBrowse link
G PHF19 PHD finger protein 19 decreases expression EXP beryllium sulfate results in decreased expression of PHF19 mRNA CTD PMID:35679967 NCBI chr 9:120,855,651...120,904,128
Ensembl chr 9:120,855,651...120,894,896
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP beryllium sulfate results in increased expression of PTGS2 mRNA; beryllium sulfate results in increased expression of PTGS2 protein
[sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in increased expression of PTGS2 mRNA]
CTD PMID:33197057 PMID:36843388 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RBM14-RBM4 RBM14-RBM4 readthrough decreases expression EXP beryllium sulfate results in decreased expression of RBM14-RBM4 mRNA CTD PMID:35679967 NCBI chr11:66,616,630...66,646,468
Ensembl chr11:66,616,626...66,646,469
JBrowse link
G RHOA ras homolog family member A increases expression EXP beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G RPL22 ribosomal protein L22 increases expression EXP beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 1:6,185,020...6,199,595
Ensembl chr 1:6,185,020...6,209,389
JBrowse link
G RPL30 ribosomal protein L30 increases expression EXP beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr 8:98,041,721...98,045,545
Ensembl chr 8:98,024,851...98,046,469
JBrowse link
G RPL37A ribosomal protein L37a increases expression EXP beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 2:216,498,844...216,504,086
Ensembl chr 2:216,498,825...216,579,180
JBrowse link
G RPS7 ribosomal protein S7 increases expression EXP beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920
JBrowse link
G RUNX1 RUNX family transcription factor 1 multiple interactions EXP beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SERPINB2 serpin family B member 2 increases expression EXP beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888
JBrowse link
G SFTPD surfactant protein D increases expression EXP beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614
JBrowse link
G SLC7A11 solute carrier family 7 member 11 multiple interactions
decreases expression
EXP [sodium bisulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]; Deferoxamine inhibits the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA]; NCOA4 protein affects the reaction [beryllium sulfate results in decreased expression of SLC7A11 mRNA] CTD PMID:36843388 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G TAT tyrosine aminotransferase multiple interactions ISO beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
G THSD7A thrombospondin type 1 domain containing 7A decreases expression
increases expression
EXP beryllium sulfate results in decreased expression of THSD7A mRNA
beryllium sulfate results in increased expression of THSD7A mRNA
CTD PMID:35679967 NCBI chr 7:11,370,365...11,832,198
Ensembl chr 7:11,370,365...11,832,198
JBrowse link
G TMSB4X thymosin beta 4 X-linked increases expression EXP beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
ISO
EXP
beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710 PMID:10755711 PMID:33197057 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
EXP beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767 PMID:20974702 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G WNT4 Wnt family member 4 increases expression EXP beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G ZNF77 zinc finger protein 77 increases expression EXP beryllium sulfate results in increased expression of ZNF77 mRNA CTD PMID:16314022 NCBI chr19:2,933,218...2,950,625
Ensembl chr19:2,933,218...2,944,971
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    chemical entity 26024
      molecular entity 25991
        ion 18767
          cation 18463
            monoatomic cation 16919
              monoatomic dication 10160
                beryllium(2+) 96
                  beryllium sulfate + 96
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    main group molecular entity 25834
                      s-block molecular entity 25166
                        alkaline earth molecular entity 922
                          beryllium molecular entity 108
                            elemental beryllium 99
                              monoatomic beryllium 96
                                beryllium ion 96
                                  beryllium cation 96
                                    beryllium(2+) 96
                                      beryllium sulfate + 96
paths to the root