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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fentin hydroxide
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Accession:CHEBI:30473 term browser browse the term
Definition:An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a hydroxy group. A fungicide used to control a variety of infections including blight on potatoes, leaf spot on sugar beet and alternaria blight on carrots.
Synonyms:exact_synonym: triphenylstannanol
 related_synonym: Fentin;   Formula=C18H16OSn;   InChI=1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1;   InChIKey=BFWMWWXRWVJXSE-UHFFFAOYSA-M;   SMILES=O[Sn](c1ccccc1)(c1ccccc1)c1ccccc1;   Sn(OH)Ph3;   hydroxytriphenylstannane;   hydroxytriphenyltin;   triphenylstannylium hydroxide;   triphenyltin hydroxide
 xref: AGR:IND20426744;   AGR:IND79056532;   Beilstein:4139186;   CAS:76-87-9;   Gmelin:7194;   KEGG:C18729
 xref_mesh: MESH:C007567
 xref: MolBase:332;   PMID:16162336;   PMID:16806747;   PMID:20563930;   PMID:3232835;   PMID:5675476;   PPDB:312;   Reaxys:3770576


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fentin hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [triphenyltin hydroxide binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein
triphenyltin hydroxide results in increased expression of CYP19A1 mRNA
CTD PMID:15941851 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:32473317 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 increases activity
increases expression
ISO triphenyltin hydroxide results in increased activity of HSD17B1 protein
triphenyltin hydroxide results in increased expression of HSD17B1 mRNA
CTD PMID:16513093 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Ins2 insulin 2 multiple interactions ISO triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA] CTD PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA] CTD PMID:32473317 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO triphenyltin hydroxide results in increased expression of PPARG mRNA CTD PMID:32473317 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [triphenyltin hydroxide binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein; Alitretinoin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; tributyltin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; triphenyltin chloride inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; triphenyltin hydroxide binds to and affects the activity of RXRA protein; triphenyltin hydroxide inhibits the reaction [Alitretinoin binds to RXRA protein] CTD PMID:15941851 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO triphenyltin hydroxide binds to and affects the activity of RXRB protein CTD PMID:15941851 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Rxrg retinoid X receptor gamma multiple interactions ISO triphenyltin hydroxide binds to and affects the activity of RXRG protein CTD PMID:15941851 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO triphenyltin hydroxide results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO triphenyltin hydroxide binds to THRB protein CTD PMID:31476497 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
fentin acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor increases expression ISO phentin acetate results in increased expression of AR mRNA CTD PMID:12711008 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Folh1 folate hydrolase 1 increases expression ISO phentin acetate results in increased expression of FOLH1 mRNA CTD PMID:12711008 NCBI chr 1:150,323,768...150,395,415
Ensembl chr 1:150,323,768...150,395,415
JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO phentin acetate results in decreased expression of NKX3-1 mRNA CTD PMID:12711008 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression ISO phentin acetate results in decreased expression of PMEPA1 mRNA CTD PMID:12711008 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Tmprss2 transmembrane serine protease 2 affects expression ISO phentin acetate affects the expression of TMPRSS2 mRNA CTD PMID:12711008 NCBI chr11:38,063,914...38,103,406
Ensembl chr11:38,063,915...38,103,290
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        pesticide 16430
          acaricide 9730
            fentin hydroxide 18
              fentin acetate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organometallic compound 6725
                              organotin compound 1166
                                triphenylstannane 116
                                  fentin hydroxide 18
                                    fentin acetate 5
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