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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fentin hydroxide
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Accession:CHEBI:30473 term browser browse the term
Definition:An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a hydroxy group. A fungicide used to control a variety of infections including blight on potatoes, leaf spot on sugar beet and alternaria blight on carrots.
Synonyms:exact_synonym: triphenylstannanol
 related_synonym: Fentin;   Formula=C18H16OSn;   InChI=1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1;   InChIKey=BFWMWWXRWVJXSE-UHFFFAOYSA-M;   SMILES=O[Sn](c1ccccc1)(c1ccccc1)c1ccccc1;   Sn(OH)Ph3;   hydroxytriphenylstannane;   hydroxytriphenyltin;   triphenylstannylium hydroxide;   triphenyltin hydroxide
 xref: AGR:IND20426744;   AGR:IND79056532;   Beilstein:4139186;   CAS:76-87-9;   Gmelin:7194;   KEGG:C18729
 xref_mesh: MESH:C007567
 xref: MolBase:332;   PMID:16162336;   PMID:16806747;   PMID:20563930;   PMID:3232835;   PMID:5675476;   PPDB:312;   Reaxys:3770576



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fentin hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] CTD PMID:32473317 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [triphenyltin hydroxide binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein
triphenyltin hydroxide results in increased expression of CYP19A1 mRNA
CTD PMID:15941851 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:32473317 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 increases activity
increases expression
ISO triphenyltin hydroxide results in increased activity of HSD17B1 protein
triphenyltin hydroxide results in increased expression of HSD17B1 mRNA
CTD PMID:16513093 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Ins2 insulin 2 multiple interactions ISO triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA] CTD PMID:32473317 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA] CTD PMID:32473317 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO triphenyltin hydroxide results in increased expression of PPARG mRNA CTD PMID:32473317 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [triphenyltin hydroxide binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein; Alitretinoin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; tributyltin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; triphenyltin chloride inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]; triphenyltin hydroxide binds to and affects the activity of RXRA protein; triphenyltin hydroxide inhibits the reaction [Alitretinoin binds to RXRA protein] CTD PMID:15941851 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO triphenyltin hydroxide binds to and affects the activity of RXRB protein CTD PMID:15941851 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Rxrg retinoid X receptor gamma multiple interactions ISO triphenyltin hydroxide binds to and affects the activity of RXRG protein CTD PMID:15941851 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA] CTD PMID:32473317 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO triphenyltin hydroxide results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO triphenyltin hydroxide binds to THRB protein CTD PMID:31476497 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO triphenyltin hydroxide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein] CTD PMID:33929904 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
fentin acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor increases expression ISO phentin acetate results in increased expression of AR mRNA CTD PMID:12711008 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Folh1 folate hydrolase 1 increases expression ISO phentin acetate results in increased expression of FOLH1 mRNA CTD PMID:12711008 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO phentin acetate results in decreased expression of KLK3 mRNA CTD PMID:12711008 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO phentin acetate results in decreased expression of NKX3-1 mRNA CTD PMID:12711008 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression ISO phentin acetate results in decreased expression of PMEPA1 mRNA CTD PMID:12711008 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Tp53 tumor protein p53 affects activity ISO phentin acetate affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      application 19650
        pesticide 17923
          acaricide 13712
            fentin hydroxide 20
              fentin acetate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organometallic compound 6901
                              organotin compound 1241
                                triphenylstannane 217
                                  fentin hydroxide 20
                                    fentin acetate 6
paths to the root