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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzthiazide
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Accession:CHEBI:3047 term browser browse the term
Definition:7-Sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by chlorine and that at position 3 is substituted by a benzylsulfanylmethyl group. A diuretic, it is used to treat hypertension and edema.
Synonyms:exact_synonym: 3-[(benzylsulfanyl)methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
 related_synonym: 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide;   3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;   3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide;   6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;   6-chloro-7-sulfamoyl-3-benzylthiomethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide;   Formula=C15H14ClN3O4S3;   InChI=1S/C15H14ClN3O4S3/c16-11-6-12-14(7-13(11)25(17,20)21)26(22,23)19-15(18-12)9-24-8-10-4-2-1-3-5-10/h1-7H,8-9H2,(H,18,19)(H2,17,20,21);   InChIKey=NDTSRXAMMQDVSW-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc2c(cc1Cl)N=C(CSCc1ccccc1)NS2(=O)=O;   benzothiazide;   benzotiazida;   benzthiazidum
 xref: Beilstein:722681;   CAS:91-33-8;   DrugBank:DB00562;   Drug_Central:332;   KEGG:C07759;   KEGG:D00651;   LINCS:LSM-2474;   Patent:DE1137740;   Patent:US3440244;   Wikipedia:Benzthiazide


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Term Annotations click to browse term
  CHEBI ontology 494
    role 501
      application 452
        pharmaceutical 453
          drug 446
            diuretic 8
              benzthiazide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 494
    subatomic particle 494
      composite particle 494
        hadron 501
          baryon 494
            nucleon 494
              atomic nucleus 494
                atom 494
                  main group element atom 487
                    p-block element atom 487
                      chalcogen 445
                        oxygen atom 448
                          oxygen molecular entity 443
                            hydroxides 418
                              oxoacid 373
                                chalcogen oxoacid 13
                                  sulfur oxoacid 13
                                    sulfonic acid 12
                                      sulfonic acid derivative 12
                                        sulfonamide 9
                                          benzthiazide 0
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