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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzphetamine
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Accession:CHEBI:3044 term browser browse the term
Definition:Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity.
Synonyms:exact_synonym: (2S)-N-benzyl-N-methyl-1-phenylpropan-2-amine
 related_synonym: (+)-N,alpha-dimethyl-N-(phenylmethyl)-benzeneethanamine;   (+)-N-benzyl-N,alpha-dimethylphenethylamine;   (S)-(+)-N-benzyl-N,alpha-dimethylphenethylamine;   (S)-benzphetamine;   (alphaS)-N,alpha-dimethylphenethylamine;   Formula=C17H21N;   InChI=1S/C17H21N/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17/h3-12,15H,13-14H2,1-2H3/t15-/m0/s1;   InChIKey=YXKTVDFXDRQTKV-HNNXBMFYSA-N;   N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine;   SMILES=C[C@@H](Cc1ccccc1)N(C)Cc1ccccc1;   benzaphetamine;   benzfetamina;   benzfetamine;   benzfetaminum;   benzylamphetamine;   d-N-methyl-N-benzyl-beta-phenylisopropylamine
 xref: Beilstein:3203999;   CAS:156-08-1;   DrugBank:DB00865;   Drug_Central:329;   KEGG:C07538;   KEGG:D07514
 xref_mesh: MESH:D001589
 xref: Patent:US2789138


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benzphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of Benzphetamine CTD PMID:12464242, PMID:15769884 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        pharmacological role 18797
          neurotransmitter agent 16425
            adrenergic agent 8935
              sympathomimetic agent 5406
                benzphetamine 1
                  benzphetamine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        amine 7602
                                          tertiary amine 616
                                            benzphetamine 1
                                              benzphetamine hydrochloride 0
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