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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzphetamine
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Accession:CHEBI:3044 term browser browse the term
Definition:Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity.
Synonyms:exact_synonym: (2S)-N-benzyl-N-methyl-1-phenylpropan-2-amine
 related_synonym: (+)-N,alpha-dimethyl-N-(phenylmethyl)-benzeneethanamine;   (+)-N-benzyl-N,alpha-dimethylphenethylamine;   (S)-(+)-N-benzyl-N,alpha-dimethylphenethylamine;   (S)-benzphetamine;   (alphaS)-N,alpha-dimethylphenethylamine;   Benzfetamine;   Formula=C17H21N;   InChI=1S/C17H21N/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17/h3-12,15H,13-14H2,1-2H3/t15-/m0/s1;   InChIKey=YXKTVDFXDRQTKV-HNNXBMFYSA-N;   N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine;   SMILES=C[C@@H](Cc1ccccc1)N(C)Cc1ccccc1;   benzaphetamine;   benzfetamina;   benzfetaminum;   benzylamphetamine;   d-N-methyl-N-benzyl-beta-phenylisopropylamine
 xref: Beilstein:3203999;   CAS:156-08-1;   DrugBank:DB00865;   Drug_Central:329;   KEGG:C07538;   KEGG:D07514
 xref_mesh: MESH:D001589
 xref: Patent:US2789138


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benzphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of Benzphetamine CTD PMID:12464242 PMID:15769884 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO Benzphetamine inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin] CTD PMID:19299527 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        pharmacological role 19106
          neurotransmitter agent 16806
            adrenergic agent 9181
              sympathomimetic agent 5570
                benzphetamine 2
                  benzphetamine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      s-block molecular entity 19681
                        hydrogen molecular entity 19662
                          hydrides 19167
                            inorganic hydride 18182
                              pnictogen hydride 18172
                                nitrogen hydride 18085
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17888
                                        amine 8308
                                          tertiary amine 645
                                            benzphetamine 2
                                              benzphetamine hydrochloride 0
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