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G |
Casp3 |
caspase 3 |
increases cleavage |
ISO |
antimony trichloride results in increased cleavage of CASP3 protein |
CTD |
PMID:30055241 |
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Ddb1 |
damage specific DNA binding protein 1 |
decreases expression |
ISO |
antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein |
CTD |
PMID:20509621 |
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NCBI chr19:10,582,932...10,607,192
Ensembl chr19:10,582,691...10,607,183
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:30055241 |
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk3 |
mitogen-activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
antimony trichloride results in increased phosphorylation of MAPK3 protein Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:30055241 |
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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G |
Sirt1 |
sirtuin 1 |
decreases expression multiple interactions |
ISO |
antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein] |
CTD |
PMID:30055241 |
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NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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G |
Xpa |
xeroderma pigmentosum, complementation group A |
multiple interactions affects binding |
ISO |
antimony trichloride inhibits the reaction [XPA protein binds to Zinc] antimony trichloride binds to XPA protein |
CTD |
PMID:20509621 |
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NCBI chr 4:46,175,222...46,196,345
Ensembl chr 4:46,155,347...46,196,311
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