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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression |
EXP |
[Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ATF6 mRNA antimony trichloride results in increased expression of ATF6 mRNA |
CTD |
PMID:34091186 |
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NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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G |
Atp2a2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
decreases expression multiple interactions |
EXP |
antimony trichloride results in decreased expression of ATP2A2 mRNA; antimony trichloride results in decreased expression of ATP2A2 protein [Arsenic Trioxide co-treated with antimony trichloride] results in decreased expression of ATP2A2 mRNA; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of ATP2A2 protein] |
CTD |
PMID:34091186 |
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NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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G |
Camk2g |
calcium/calmodulin-dependent protein kinase II gamma |
multiple interactions |
EXP |
[Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of CAMK2G mRNA |
CTD |
PMID:34091186 |
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NCBI chr14:20,784,943...20,844,225
Ensembl chr14:20,784,943...20,844,156
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G |
Casp12 |
caspase 12 |
increases expression multiple interactions |
EXP |
antimony trichloride results in increased expression of CASP12 mRNA [arsenic trichloride co-treated with antimony trichloride] results in increased expression of CASP12 mRNA |
CTD |
PMID:34091186 |
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NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
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G |
Casp3 |
caspase 3 |
increases cleavage increases expression multiple interactions |
ISO EXP |
antimony trichloride results in increased cleavage of CASP3 protein antimony trichloride results in increased expression of CASP3 mRNA arsenic trichloride promotes the reaction [antimony trichloride results in increased cleavage of CASP3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of CASP3 mRNA] |
CTD |
PMID:30055241 PMID:34091186 |
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Ddb1 |
damage specific DNA binding protein 1 |
decreases expression |
ISO |
antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein |
CTD |
PMID:20509621 |
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NCBI chr19:10,582,961...10,607,186
Ensembl chr19:10,582,691...10,607,183
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
EXP |
antimony trichloride promotes the reaction [arsenic trichloride results in increased expression of DDIT3 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of DDIT3 protein] antimony trichloride results in increased expression of DDIT3 mRNA; antimony trichloride results in increased expression of DDIT3 protein |
CTD |
PMID:34091186 |
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NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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G |
Ern2 |
endoplasmic reticulum to nucleus signalling 2 |
multiple interactions increases expression |
EXP |
[Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ERN2 mRNA antimony trichloride results in increased expression of ERN2 mRNA |
CTD |
PMID:34091186 |
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NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430
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G |
Hspa5 |
heat shock protein 5 |
increases expression multiple interactions |
EXP |
antimony trichloride results in increased expression of HSPA5 mRNA; antimony trichloride results in increased expression of HSPA5 protein [arsenic trichloride co-treated with antimony trichloride] results in increased expression of HSPA5 protein; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of HSPA5 mRNA] |
CTD |
PMID:34091186 |
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NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
Itpr2 |
inositol 1,4,5-triphosphate receptor 2 |
increases expression multiple interactions |
EXP |
antimony trichloride results in increased expression of ITPR2 mRNA antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of ITPR2 mRNA]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of ITPR2 mRNA] |
CTD |
PMID:34091186 |
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NCBI chr 6:146,009,797...146,403,757
Ensembl chr 6:146,009,797...146,403,721
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:30055241 |
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk3 |
mitogen-activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
antimony trichloride results in increased phosphorylation of MAPK3 protein Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:30055241 |
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases expression |
EXP |
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of MAPK8 mRNA; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of MAPK8 protein] |
CTD |
PMID:34091186 |
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NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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G |
Ryr2 |
ryanodine receptor 2, cardiac |
increases expression multiple interactions |
EXP |
antimony trichloride results in increased expression of RYR2 mRNA; antimony trichloride results in increased expression of RYR2 protein [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of RYR2 mRNA; antimony trichloride promotes the reaction [Arsenic Trioxide results in decreased expression of RYR2 protein]; Arsenic Trioxide promotes the reaction [antimony trichloride results in decreased expression of RYR2 protein] |
CTD |
PMID:34091186 |
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NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831
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G |
Sirt1 |
sirtuin 1 |
decreases expression multiple interactions |
ISO |
antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein] |
CTD |
PMID:30055241 |
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NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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G |
Trp53 |
transformation related protein 53 |
increases expression multiple interactions |
EXP |
antimony trichloride results in increased expression of TRP53 mRNA; antimony trichloride results in increased expression of TRP53 protein antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of TRP53 protein]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 mRNA]; arsenic trichloride promotes the reaction [antimony trichloride results in increased expression of TRP53 protein]; Arsenic Trioxide promotes the reaction [antimony trichloride results in increased expression of TRP53 protein] |
CTD |
PMID:34091186 |
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NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions increases expression |
EXP |
[arsenic trichloride co-treated with antimony trichloride] results in increased expression of XBP1 mRNA; antimony trichloride promotes the reaction [Arsenic Trioxide results in increased expression of XBP1 protein]; arsenic trichloride inhibits the reaction [antimony trichloride results in increased expression of XBP1 protein] antimony trichloride results in increased expression of XBP1 mRNA; antimony trichloride results in increased expression of XBP1 protein |
CTD |
PMID:34091186 |
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NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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G |
Xpa |
xeroderma pigmentosum, complementation group A |
multiple interactions affects binding |
ISO |
antimony trichloride inhibits the reaction [XPA protein binds to Zinc] antimony trichloride binds to XPA protein |
CTD |
PMID:20509621 |
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NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311
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