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G |
CASP3 |
caspase 3 |
increases cleavage |
EXP |
antimony trichloride results in increased cleavage of CASP3 protein |
CTD |
PMID:30055241 |
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
DDB1 |
damage specific DNA binding protein 1 |
decreases expression |
EXP |
antimony trichloride results in decreased expression of DDB1 mRNA; antimony trichloride results in decreased expression of DDB1 protein |
CTD |
PMID:20509621 |
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NCBI chr11:61,299,451...61,333,105
Ensembl chr11:61,299,451...61,342,596
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
increases phosphorylation multiple interactions |
EXP |
antimony trichloride results in increased phosphorylation of MAPK1 protein Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:30055241 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
increases phosphorylation multiple interactions |
EXP |
antimony trichloride results in increased phosphorylation of MAPK3 protein Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:30055241 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
SIRT1 |
sirtuin 1 |
decreases expression multiple interactions |
EXP |
antimony trichloride results in decreased expression of SIRT1 mRNA; antimony trichloride results in decreased expression of SIRT1 protein Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; U 0126 inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein] |
CTD |
PMID:30055241 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
XPA |
XPA, DNA damage recognition and repair factor |
multiple interactions affects binding |
EXP |
antimony trichloride inhibits the reaction [XPA protein binds to Zinc] antimony trichloride binds to XPA protein |
CTD |
PMID:20509621 |
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NCBI chr 9:97,654,398...97,697,340
Ensembl chr 9:97,674,909...97,697,340
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