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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzbromarone
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Accession:CHEBI:3023 term browser browse the term
Definition:1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Synonyms:exact_synonym: (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
 related_synonym: 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran;   3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone;   Formula=C17H12Br2O3;   InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3;   InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N;   SMILES=CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1;   Uroleap (TN)
 xref: Beilstein:273668;   CAS:3562-84-3;   Drug_Central:318;   KEGG:D01056;   LINCS:LSM-2239
 xref_mesh: MESH:D001553
 xref: PMID:18636784;   PMID:26693855;   PMID:26792818;   PMID:27391386;   PMID:28131653;   PMID:28166217;   PMID:28202260;   PMID:7661033



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benzbromarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases activity
multiple interactions
ISO Benzbromarone results in decreased activity of ABCB11 protein
Benzbromarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A affects expression ISO Benzbromarone affects the expression of ABCB1A mRNA CTD PMID:19483382 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases activity ISO Benzbromarone results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions
affects activity
ISO Benzbromarone inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Benzbromarone inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin]
Benzbromarone affects the activity of ABCC1 protein
CTD PMID:9096673 PMID:9334814 PMID:15041471 PMID:16101123 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions
decreases activity
ISO [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium
Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:19782883 PMID:19853032 PMID:22646477 PMID:31348918 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions ISO Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 multiple interactions ISO Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 multiple interactions
decreases activity
affects expression
ISO Benzbromarone inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione]
Benzbromarone results in decreased activity of ABCC6 protein
Benzbromarone affects the expression of ABCC6 mRNA
CTD PMID:11880368 PMID:14667841 PMID:19483382 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression ISO Benzbromarone affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression ISO Benzbromarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 5:31,107,410...31,112,439
Ensembl chr 5:31,107,410...31,112,435
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression ISO Benzbromarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 9:106,324,936...106,330,122
Ensembl chr 9:106,324,658...106,330,122
JBrowse link
G Abhd17a abhydrolase domain containing 17A affects expression ISO Benzbromarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr10:80,419,483...80,426,199
Ensembl chr10:80,419,488...80,426,175
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha affects expression ISO Benzbromarone affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acadl acyl-Coenzyme A dehydrogenase, long-chain affects expression ISO Benzbromarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 1:66,869,998...66,902,468
Ensembl chr 1:66,869,998...66,902,436
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Benzbromarone results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Aco1 aconitase 1 affects expression ISO Benzbromarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Aco2 aconitase 2, mitochondrial affects expression ISO Benzbromarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression ISO Benzbromarone affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr13:91,889,635...91,934,271
Ensembl chr13:91,889,631...91,934,267
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression ISO Benzbromarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr12:84,084,028...84,091,497
Ensembl chr12:84,085,153...84,095,375
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression ISO Benzbromarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303
JBrowse link
G Add1 adducin 1 affects expression ISO Benzbromarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr 5:34,731,008...34,789,652
Ensembl chr 5:34,731,008...34,789,652
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression ISO Benzbromarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
EXP
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [Benzbromarone results in increased expression of ADIPOQ mRNA]
Benzbromarone results in increased expression of ADIPOQ protein
CTD PMID:19048458 PMID:21329621 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adtrp androgen dependent TFPI regulating protein affects expression ISO Benzbromarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160
JBrowse link
G Afm afamin affects expression ISO Benzbromarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402
JBrowse link
G Agt angiotensinogen affects expression ISO Benzbromarone affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression ISO Benzbromarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 affects expression ISO Benzbromarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 decreases activity ISO Benzbromarone results in decreased activity of AKR1C3 protein CTD PMID:12604236 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Akr1c20 aldo-keto reductase family 1, member C20 multiple interactions ISO Benzbromarone binds to and results in decreased activity of AKR1C1 protein CTD PMID:12604236 NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344
JBrowse link
G Akr1c21 aldo-keto reductase family 1, member C21 decreases activity ISO Benzbromarone results in decreased activity of AKR1C2 protein CTD PMID:12604236 NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540
JBrowse link
G Akr1c6 aldo-keto reductase family 1, member C6 decreases activity ISO Benzbromarone results in decreased activity of AKR1C4 protein CTD PMID:12604236 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876
JBrowse link
G Akr7a5 aldo-keto reductase family 7, member A5 affects expression ISO Benzbromarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects expression ISO Benzbromarone affects the expression of ALDH1A1 mRNA CTD PMID:19483382 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial affects expression ISO Benzbromarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
JBrowse link
G Alkbh7 alkB homolog 7 affects expression ISO Benzbromarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr17:57,304,339...57,306,340
Ensembl chr17:57,304,339...57,306,322
JBrowse link
G Ap2m1 adaptor-related protein complex 2, mu 1 subunit affects expression ISO Benzbromarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr16:20,354,230...20,363,659
Ensembl chr16:20,354,228...20,363,659
JBrowse link
G Apcs amyloid P component, serum affects expression ISO Benzbromarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608
JBrowse link
G Apoa4 apolipoprotein A-IV affects expression ISO Benzbromarone affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Apoh apolipoprotein H affects expression ISO Benzbromarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222
JBrowse link
G Apool apolipoprotein O-like affects expression ISO Benzbromarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:111,221,049...111,282,452
Ensembl chr  X:111,221,031...111,282,452
JBrowse link
G Arg1 arginase, liver affects expression ISO Benzbromarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
JBrowse link
G Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 affects expression ISO Benzbromarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 7:117,718,113...117,728,848
Ensembl chr 7:117,718,114...117,728,885
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression ISO Benzbromarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr11:69,983,470...69,997,013
Ensembl chr11:69,983,470...69,997,013
JBrowse link
G Atf5 activating transcription factor 5 affects expression ISO Benzbromarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression ISO Benzbromarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 2:174,302,868...174,305,894
Ensembl chr 2:174,302,865...174,305,898
JBrowse link
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 affects expression ISO Benzbromarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:12,453,998...12,483,290
Ensembl chr  X:12,454,040...12,483,288
JBrowse link
G Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A affects expression ISO Benzbromarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr16:43,905,765...43,960,055
Ensembl chr16:43,905,765...43,960,068
JBrowse link
G Atp6v1f ATPase, H+ transporting, lysosomal V1 subunit F affects expression ISO Benzbromarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 6:29,467,782...29,470,508
Ensembl chr 6:29,467,717...29,470,511
JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase affects expression ISO Benzbromarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557
JBrowse link
G Bcl6b B cell CLL/lymphoma 6, member B affects expression ISO Benzbromarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr11:70,114,953...70,120,624
Ensembl chr11:70,114,954...70,120,624
JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression ISO Benzbromarone affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr10:89,580,830...89,655,753
Ensembl chr10:89,580,853...89,655,733
JBrowse link
G Bmf BCL2 modifying factor affects expression ISO Benzbromarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 affects expression ISO Benzbromarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Btf3 basic transcription factor 3 affects expression ISO Benzbromarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr13:98,446,405...98,453,514
Ensembl chr13:98,446,404...98,453,514
JBrowse link
G C1qbp complement component 1, q subcomponent binding protein affects expression ISO Benzbromarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr11:70,868,672...70,873,852
Ensembl chr11:70,868,662...70,873,852
JBrowse link
G C1s1 complement component 1, s subcomponent 1 affects expression ISO Benzbromarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 6:124,507,303...124,519,340
Ensembl chr 6:124,507,304...124,519,318
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression ISO Benzbromarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr16:97,656,409...97,727,248
Ensembl chr16:97,656,409...97,763,798
JBrowse link
G C7 complement component 7 affects expression ISO Benzbromarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr15:5,017,232...5,093,230
Ensembl chr15:5,018,244...5,093,222
JBrowse link
G C8b complement component 8, beta polypeptide affects expression ISO Benzbromarone affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 4:104,623,514...104,661,745
Ensembl chr 4:104,623,514...104,661,745
JBrowse link
G Cadps2 Ca2+-dependent activator protein for secretion 2 affects expression ISO Benzbromarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 6:23,262,765...23,840,662
Ensembl chr 6:23,262,772...23,839,420
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression ISO Benzbromarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 2:103,593,292...103,627,946
Ensembl chr 2:103,593,286...103,627,994
JBrowse link
G Car2 carbonic anhydrase 2 affects expression ISO Benzbromarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Car3 carbonic anhydrase 3 affects expression ISO Benzbromarone affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
JBrowse link
G Casp3 caspase 3 affects expression ISO Benzbromarone affects the expression of CASP3 mRNA CTD PMID:19483382 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase increases activity ISO Benzbromarone results in increased activity of CAT protein CTD PMID:2260096 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO Benzbromarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Cd36 CD36 molecule increases expression EXP Benzbromarone results in increased expression of CD36 mRNA CTD PMID:19048458 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cdo1 cysteine dioxygenase 1, cytosolic affects expression ISO Benzbromarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462
JBrowse link
G Cept1 choline/ethanolaminephosphotransferase 1 affects expression ISO Benzbromarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 3:106,409,576...106,455,118
Ensembl chr 3:106,409,576...106,455,118
JBrowse link
G Ces2h carboxylesterase 2H affects expression ISO Benzbromarone affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cfi complement component factor i affects expression ISO Benzbromarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 3:129,630,432...129,668,978
Ensembl chr 3:129,629,533...129,668,981
JBrowse link
G Chp1 calcineurin-like EF hand protein 1 affects expression ISO Benzbromarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 2:119,378,172...119,417,505
Ensembl chr 2:119,378,178...119,417,508
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression ISO Benzbromarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr10:71,166,324...71,180,679
Ensembl chr10:71,166,310...71,180,784
JBrowse link
G Clcn4 chloride channel, voltage-sensitive 4 affects expression ISO Benzbromarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr 7:7,285,308...7,303,837
Ensembl chr 7:7,285,308...7,303,850
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression ISO Benzbromarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr17:57,297,264...57,303,371
Ensembl chr17:57,297,305...57,303,188
JBrowse link
G Clptm1l CLPTM1-like affects expression ISO Benzbromarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr13:73,752,121...73,768,758
Ensembl chr13:73,752,125...73,768,724
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression ISO Benzbromarone affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr15:31,565,314...31,590,266
Ensembl chr15:31,565,535...31,590,265
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression ISO Benzbromarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 4:114,817,810...114,844,425
Ensembl chr 4:114,816,533...114,844,438
JBrowse link
G Copg1 coatomer protein complex, subunit gamma 1 affects expression ISO Benzbromarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 6:87,864,801...87,890,577
Ensembl chr 6:87,864,796...87,890,577
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression ISO Benzbromarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr 5:100,666,223...100,695,668
Ensembl chr 5:100,666,175...100,695,669
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression ISO Benzbromarone affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 4:21,879,646...21,912,163
Ensembl chr 4:21,879,673...21,912,162
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 affects expression ISO Benzbromarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946
JBrowse link
G Cpn1 carboxypeptidase N, polypeptide 1 affects expression ISO Benzbromarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr19:43,944,746...43,974,990
Ensembl chr19:43,944,746...43,974,995
JBrowse link
G Cpq carboxypeptidase Q affects expression ISO Benzbromarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr15:33,083,275...33,594,698
Ensembl chr15:33,083,275...33,594,698
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression ISO Benzbromarone results in increased expression of CPT1A mRNA; Benzbromarone results in increased expression of CPT1A protein CTD PMID:25108121 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Crem cAMP responsive element modulator affects expression ISO Benzbromarone affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions
decreases expression
ISO Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein]
Benzbromarone results in decreased expression of CRP protein
CTD PMID:21329621 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csnk2b casein kinase 2, beta polypeptide affects expression ISO Benzbromarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression ISO Benzbromarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr 1:135,614,650...135,679,970
Ensembl chr 1:135,647,799...135,679,970
JBrowse link
G Ctnna1 catenin alpha 1 affects expression ISO Benzbromarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Benzbromarone results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Benzbromarone results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 affects expression ISO Benzbromarone affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 affects expression ISO Benzbromarone affects the expression of CYP2B3 mRNA CTD PMID:19483382 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 affects expression ISO Benzbromarone affects the expression of CYP2B2 mRNA CTD PMID:19483382 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein; Benzbromarone binds to and results in decreased activity of CYP2C19 protein CTD PMID:15615526 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 affects binding
multiple interactions
affects metabolic processing
ISO Benzbromarone binds to CYP2C9 protein
Benzbromarone analog binds to and results in decreased activity of CYP2C9 protein; Benzbromarone binds to and results in decreased activity of CYP2C9 protein; Benzbromarone inhibits the reaction [CYP2C9 protein affects the metabolism of Diclofenac]; Benzbromarone inhibits the reaction [CYP2C9 protein affects the metabolism of Warfarin]; Benzbromarone inhibits the reaction [CYP2C9 protein polymorphism affects the hydroxylation of Flurbiprofen]; Benzbromarone promotes the reaction [CYP2C9 protein affects the metabolism of Naproxen]; Benzbromarone promotes the reaction [CYP2C9 protein polymorphism affects the hydroxylation of Flurbiprofen]
CYP2C9 protein affects the metabolism of Benzbromarone
CTD PMID:10613612 PMID:12814975 PMID:15170332 PMID:15955872 PMID:16081671 More... NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 affects expression ISO Benzbromarone affects the expression of CYP2D4 mRNA CTD PMID:19483382 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 affects expression ISO Benzbromarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 affects expression ISO Benzbromarone affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 affects expression ISO Benzbromarone affects the expression of CYP3A9 mRNA CTD PMID:19483382 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp4f16 cytochrome P450, family 4, subfamily f, polypeptide 16 affects expression ISO Benzbromarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr17:32,755,517...32,770,772
Ensembl chr17:32,755,532...32,770,772
JBrowse link
G Dbi diazepam binding inhibitor affects expression ISO Benzbromarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr 1:120,041,010...120,048,826
Ensembl chr 1:120,041,010...120,048,808
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression ISO Benzbromarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr14:55,796,557...55,807,522
Ensembl chr14:55,797,463...55,807,522
JBrowse link
G Dcxr dicarbonyl L-xylulose reductase affects expression ISO Benzbromarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr11:120,615,372...120,618,110
Ensembl chr11:120,616,225...120,618,107
JBrowse link
G Decr1 2,4-dienoyl CoA reductase 1, mitochondrial affects expression ISO Benzbromarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 4:15,917,240...15,945,377
Ensembl chr 4:15,917,240...15,945,507
JBrowse link
G Dexi dexamethasone-induced transcript affects expression ISO Benzbromarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr16:10,348,071...10,360,918
Ensembl chr16:10,320,395...10,360,918
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression ISO Benzbromarone affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression ISO Benzbromarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression ISO Benzbromarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr14:55,715,880...55,727,797
Ensembl chr14:55,716,215...55,727,797
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression ISO Benzbromarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr11:60,721,457...60,749,249
Ensembl chr11:60,721,457...60,751,021
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression ISO Benzbromarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr17:36,190,657...36,203,562
Ensembl chr17:36,190,711...36,203,562
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression ISO Benzbromarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr12:69,771,687...69,791,439
Ensembl chr12:69,771,724...69,791,434
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression ISO Benzbromarone affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression ISO Benzbromarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression ISO Benzbromarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression ISO Benzbromarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 7:121,633,385...121,666,436
Ensembl chr 7:121,636,436...121,666,486
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial affects expression ISO Benzbromarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
JBrowse link
G Eci1 enoyl-Coenzyme A delta isomerase 1 affects expression ISO Benzbromarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322
JBrowse link
G Eci2 enoyl-Coenzyme A delta isomerase 2 affects expression ISO Benzbromarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr13:35,161,731...35,211,098
Ensembl chr13:35,161,731...35,211,079
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression ISO Benzbromarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843
JBrowse link
G Ehhadh enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase affects expression ISO Benzbromarone affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr16:21,580,035...21,606,589
Ensembl chr16:21,580,037...21,606,557
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression ISO Benzbromarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr16:22,924,846...22,932,882
Ensembl chr16:22,926,194...22,932,886
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression ISO Benzbromarone affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression ISO Benzbromarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr 5:134,648,726...134,668,263
Ensembl chr 5:134,648,575...134,668,344
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression ISO Benzbromarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542
JBrowse link
G Eno1 enolase 1, alpha non-neuron affects expression ISO Benzbromarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
JBrowse link
G Enpep glutamyl aminopeptidase affects expression ISO Benzbromarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression ISO Benzbromarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression ISO Benzbromarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression ISO Benzbromarone affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569
JBrowse link
G Esd esterase D/formylglutathione hydrolase affects expression ISO Benzbromarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr14:74,969,591...74,988,205
Ensembl chr14:74,969,737...74,988,205
JBrowse link
G Etfb electron transferring flavoprotein, beta polypeptide affects expression ISO Benzbromarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 7:43,093,496...43,107,224
Ensembl chr 7:43,093,507...43,107,224
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 decreases activity ISO Benzbromarone results in decreased activity of EYA2 protein CTD PMID:22545090 NCBI chr 2:165,436,892...165,613,645
Ensembl chr 2:165,436,952...165,613,647
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 decreases activity ISO Benzbromarone results in decreased activity of EYA3 protein CTD PMID:22545090 NCBI chr 4:132,366,303...132,452,076
Ensembl chr 4:132,366,298...132,452,076
JBrowse link
G Faah fatty acid amide hydrolase affects expression ISO Benzbromarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression EXP Benzbromarone results in increased expression of FABP4 mRNA CTD PMID:19048458 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fads2 fatty acid desaturase 2 affects expression ISO Benzbromarone affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
JBrowse link
G Fbp1 fructose bisphosphatase 1 affects expression ISO Benzbromarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression ISO Benzbromarone affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027
JBrowse link
G Fdps farnesyl diphosphate synthetase affects expression ISO Benzbromarone affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
JBrowse link
G Fdx2 ferredoxin 2 affects expression ISO Benzbromarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 9:20,978,808...20,984,827
Ensembl chr 9:20,978,816...20,984,910
JBrowse link
G Fmo1 flavin containing monooxygenase 1 affects expression ISO Benzbromarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
JBrowse link
G Gamt guanidinoacetate methyltransferase affects expression ISO Benzbromarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Benzbromarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression ISO Benzbromarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr16:70,110,837...70,366,608
Ensembl chr16:70,110,837...70,366,604
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression ISO Benzbromarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 2:118,998,269...119,002,870
Ensembl chr 2:118,998,254...119,002,871
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression ISO Benzbromarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 4:20,041,963...20,066,111
Ensembl chr 4:20,042,052...20,066,750
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression ISO Benzbromarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression ISO Benzbromarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression ISO Benzbromarone affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression ISO Benzbromarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
JBrowse link
G Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) affects expression ISO Benzbromarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression ISO Benzbromarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr 5:36,622,529...36,631,421
Ensembl chr 5:36,622,342...36,631,424
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 affects expression ISO Benzbromarone affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gtf2h5 general transcription factor IIH, polypeptide 5 affects expression ISO Benzbromarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr17:6,130,103...6,135,763
Ensembl chr17:6,130,061...6,136,792
JBrowse link
G Gzma granzyme A affects expression ISO Benzbromarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515
JBrowse link
G H3f3b H3.3 histone B affects expression ISO Benzbromarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788
JBrowse link
G Hal histidine ammonia lyase affects expression ISO Benzbromarone affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression ISO Benzbromarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression ISO Benzbromarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain affects expression ISO Benzbromarone affects the expression of HBB mRNA CTD PMID:19483382
G Hdc histidine decarboxylase affects expression ISO Benzbromarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression ISO Benzbromarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr16:37,400,104...37,452,388
Ensembl chr16:37,400,515...37,452,382
JBrowse link
G Hmgn1 high mobility group nucleosomal binding domain 1 affects expression ISO Benzbromarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr16:95,922,788...95,928,925
Ensembl chr16:95,921,818...95,928,929
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression ISO Benzbromarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression ISO Benzbromarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 7:46,409,890...46,445,501
Ensembl chr 7:46,409,890...46,445,488
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression ISO Benzbromarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression ISO Benzbromarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression ISO Benzbromarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 7:130,537,933...130,587,388
Ensembl chr 7:130,537,841...130,587,390
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression ISO Benzbromarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression ISO Benzbromarone affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr17:25,096,818...25,100,985
Ensembl chr17:25,084,971...25,100,984
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO Benzbromarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein] CTD PMID:21329621 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Impa1 inositol (myo)-1(or 4)-monophosphatase 1 affects expression ISO Benzbromarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 3:10,377,016...10,396,499
Ensembl chr 3:10,377,016...10,396,499
JBrowse link
G Inhbe inhibin beta-E affects expression ISO Benzbromarone affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280
JBrowse link
G Isyna1 myo-inositol 1-phosphate synthase A1 affects expression ISO Benzbromarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr 8:71,047,131...71,049,940
Ensembl chr 8:71,047,023...71,049,940
JBrowse link
G Itih4 inter alpha-trypsin inhibitor, heavy chain 4 affects expression ISO Benzbromarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310
JBrowse link
G Iyd iodotyrosine deiodinase decreases activity ISO Benzbromarone results in decreased activity of IYD protein CTD PMID:24012475 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877
JBrowse link
G Jak1 Janus kinase 1 affects expression ISO Benzbromarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
JBrowse link
G Kdelr2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 affects expression ISO Benzbromarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr 5:143,389,575...143,407,659
Ensembl chr 5:143,389,593...143,407,656
JBrowse link
G Kdr kinase insert domain protein receptor affects expression ISO Benzbromarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Krt8 keratin 8 affects expression ISO Benzbromarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression ISO Benzbromarone affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression ISO Benzbromarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 7:122,977,026...123,029,581
Ensembl chr 7:122,969,007...123,029,581
JBrowse link
G Lipc lipase, hepatic affects expression ISO Benzbromarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lox lysyl oxidase affects expression ISO Benzbromarone affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Benzbromarone results in increased expression of LPL protein CTD PMID:18274627 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrp3 low density lipoprotein receptor-related protein 3 affects expression ISO Benzbromarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 7:34,900,303...34,914,770
Ensembl chr 7:34,899,452...34,914,923
JBrowse link
G Man2b1 mannosidase 2, alpha B1 affects expression ISO Benzbromarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr 8:85,809,941...85,824,215
Ensembl chr 8:85,809,899...85,824,911
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 affects expression ISO Benzbromarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression ISO Benzbromarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956
JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic affects expression ISO Benzbromarone affects the expression of ME1 mRNA CTD PMID:19483382 NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
JBrowse link
G Mmut methylmalonyl-Coenzyme A mutase affects expression ISO Benzbromarone affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr17:41,245,576...41,272,880
Ensembl chr17:41,245,576...41,272,879
JBrowse link
G Mro maestro affects expression ISO Benzbromarone affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:73,992,465...74,014,405
Ensembl chr18:73,992,456...74,014,404
JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression ISO Benzbromarone affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr17:46,957,094...46,961,058
Ensembl chr17:46,957,155...46,961,065
JBrowse link
G Mrpl9 mitochondrial ribosomal protein L9 affects expression ISO Benzbromarone affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 3:94,350,631...94,355,831
Ensembl chr 3:94,350,625...94,358,437
JBrowse link
G Mug2 murinoglobulin 2 affects expression ISO Benzbromarone affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 6:121,983,688...122,062,927
Ensembl chr 6:121,983,720...122,062,924
JBrowse link
G Myadm myeloid-associated differentiation marker affects expression ISO Benzbromarone affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 7:3,337,563...3,347,871
Ensembl chr 7:3,337,605...3,348,958
JBrowse link
G Mycbp2 MYC binding protein 2, E3 ubiquitin protein ligase affects expression ISO Benzbromarone affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr14:103,350,847...103,584,276
Ensembl chr14:103,350,847...103,584,250
JBrowse link
G Myo1d myosin ID affects expression ISO Benzbromarone affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr11:80,372,945...80,670,881
Ensembl chr11:80,372,952...80,670,851
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression ISO Benzbromarone affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr11:69,286,617...69,287,497
Ensembl chr11:69,286,313...69,287,506
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression ISO Benzbromarone affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr10:111,308,754...111,334,011
Ensembl chr10:111,309,084...111,334,011
JBrowse link
G Nat8 N-acetyltransferase 8 (GCN5-related) affects expression ISO Benzbromarone affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064
JBrowse link
G Ndrg2 N-myc downstream regulated gene 2 affects expression ISO Benzbromarone affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr14:52,142,738...52,151,463
Ensembl chr14:52,142,728...52,151,615
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 affects expression ISO Benzbromarone affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase core subunit V3 affects expression ISO Benzbromarone affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr17:31,739,089...31,750,300
Ensembl chr17:31,739,089...31,750,305
JBrowse link
G Neu2 neuraminidase 2 affects expression ISO Benzbromarone affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 1:87,501,749...87,525,567
Ensembl chr 1:87,437,611...87,525,567
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression ISO Benzbromarone affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 4:40,970,906...41,025,992
Ensembl chr 4:40,970,906...41,025,993
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression ISO Benzbromarone affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr15:34,572,942...34,679,739
Ensembl chr15:34,572,945...34,679,358
JBrowse link
G Nit1 nitrilase 1 affects expression ISO Benzbromarone affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr 1:171,168,145...171,173,209
Ensembl chr 1:171,165,576...171,173,214
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression ISO Benzbromarone affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression ISO Benzbromarone affects the expression of NR1I3 mRNA CTD PMID:19483382 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Benzbromarone affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Oaf out at first homolog affects expression ISO Benzbromarone affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 9:43,132,575...43,151,113
Ensembl chr 9:43,132,532...43,151,208
JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) affects expression ISO Benzbromarone affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642
JBrowse link
G Or51e2 olfactory receptor family 51 subfamily E member 2 affects expression ISO Benzbromarone affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 7:102,389,928...102,408,678
Ensembl chr 7:102,387,718...102,408,678
JBrowse link
G Ostc oligosaccharyltransferase complex subunit (non-catalytic) affects expression ISO Benzbromarone affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 3:130,489,566...130,503,093
Ensembl chr 3:130,489,561...130,503,093
JBrowse link
G Otc ornithine transcarbamylase affects expression ISO Benzbromarone affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:10,118,584...10,187,275
Ensembl chr  X:10,118,544...10,187,263
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression ISO Benzbromarone affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 4:123,172,722...123,192,718
Ensembl chr 4:123,156,144...123,192,718
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase affects expression ISO Benzbromarone affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr 5:77,099,149...77,115,356
Ensembl chr 5:77,099,154...77,115,356
JBrowse link
G Pccb propionyl Coenzyme A carboxylase, beta polypeptide affects expression ISO Benzbromarone affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 9:100,864,085...100,916,993
Ensembl chr 9:100,864,085...100,916,951
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression ISO Benzbromarone affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 7:65,511,884...65,700,134
Ensembl chr 7:65,511,482...65,700,134
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression ISO Benzbromarone affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr11:89,873,370...89,893,720
Ensembl chr11:89,873,491...89,893,720
JBrowse link
G Pcx pyruvate carboxylase affects expression ISO Benzbromarone affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
JBrowse link
G Pdcl3 phosducin-like 3 affects expression ISO Benzbromarone affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 1:39,026,895...39,036,317
Ensembl chr 1:39,024,689...39,036,319
JBrowse link
G Pdia3 protein disulfide isomerase associated 3 affects expression ISO Benzbromarone affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 affects expression ISO Benzbromarone affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression ISO Benzbromarone affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr 1:171,954,322...171,964,064
Ensembl chr 1:171,954,322...171,964,060
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression ISO Benzbromarone affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression ISO Benzbromarone affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:35,861,846...35,869,732
Ensembl chr  X:35,861,859...35,869,732
JBrowse link
G Phyh phytanoyl-CoA hydroxylase affects expression ISO Benzbromarone affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr 2:4,923,807...4,943,554
Ensembl chr 2:4,923,830...4,943,541
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression ISO Benzbromarone affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr16:94,159,622...94,171,874
Ensembl chr16:94,159,622...94,172,701
JBrowse link
G Pklr pyruvate kinase liver and red blood cell affects expression ISO Benzbromarone affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression ISO Benzbromarone affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 6:136,589,069...136,639,301
Ensembl chr 6:136,589,068...136,638,926
JBrowse link
G Plg plasminogen affects expression ISO Benzbromarone affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
JBrowse link
G Pls3 plastin 3 (T-isoform) affects expression ISO Benzbromarone affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:74,829,259...74,918,788
Ensembl chr  X:74,829,260...74,918,788
JBrowse link
G Pon2 paraoxonase 2 affects expression ISO Benzbromarone affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects expression EXP Benzbromarone affects the expression of PPARG mRNA CTD PMID:19048458 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression ISO Benzbromarone affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 2:180,828,615...180,830,297
Ensembl chr 2:180,829,040...180,830,564
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression ISO Benzbromarone affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression ISO Benzbromarone affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789
JBrowse link
G Proc protein C affects expression ISO Benzbromarone affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression ISO Benzbromarone affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr11:116,361,641...116,385,739
Ensembl chr11:116,361,671...116,385,461
JBrowse link
G Psma6 proteasome subunit alpha 6 affects expression ISO Benzbromarone affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr12:55,431,007...55,465,244
Ensembl chr12:55,431,007...55,465,239
JBrowse link
G Psmb1 proteasome (prosome, macropain) subunit, beta type 1 affects expression ISO Benzbromarone affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr17:15,695,983...15,718,538
Ensembl chr17:15,695,283...15,720,013
JBrowse link
G Psmb3 proteasome (prosome, macropain) subunit, beta type 3 affects expression ISO Benzbromarone affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr11:97,594,260...97,604,326
Ensembl chr11:97,594,225...97,604,326
JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 affects expression ISO Benzbromarone affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664
JBrowse link
G Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 affects expression ISO Benzbromarone affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 2:90,884,361...90,889,783
Ensembl chr 2:90,884,354...90,896,714
JBrowse link
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 affects expression ISO Benzbromarone affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr11:106,147,011...106,153,938
Ensembl chr11:106,146,980...106,153,946
JBrowse link
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 affects expression ISO Benzbromarone affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 1:85,992,341...86,067,017
Ensembl chr 1:85,992,109...86,066,873
JBrowse link
G Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 affects expression ISO Benzbromarone affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 3:94,939,999...94,949,880
Ensembl chr 3:94,940,005...94,949,925
JBrowse link
G Ptms parathymosin affects expression ISO Benzbromarone affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 6:124,890,638...124,894,909
Ensembl chr 6:124,890,644...124,897,066
JBrowse link
G Ptprf protein tyrosine phosphatase receptor type F affects expression ISO Benzbromarone affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602
JBrowse link
G Pttg1ip pituitary tumor-transforming 1 interacting protein affects expression ISO Benzbromarone affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr10:77,417,489...77,434,566
Ensembl chr10:77,417,554...77,434,566
JBrowse link
G Pygl liver glycogen phosphorylase affects expression ISO Benzbromarone affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
JBrowse link
G Rab5if RAB5 interacting factor affects expression ISO Benzbromarone affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 2:156,705,042...156,715,483
Ensembl chr 2:156,705,048...156,715,483
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression ISO Benzbromarone affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr15:34,484,168...34,495,392
Ensembl chr15:34,484,167...34,495,401
JBrowse link
G Rnase4 ribonuclease, RNase A family 4 affects expression ISO Benzbromarone affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr14:51,328,534...51,343,608
Ensembl chr14:51,328,534...51,343,608
JBrowse link
G Rnf103 ring finger protein 103 affects expression ISO Benzbromarone affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 6:71,470,828...71,487,864
Ensembl chr 6:71,470,878...71,487,865
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression ISO Benzbromarone affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr17:24,633,620...24,644,872
Ensembl chr17:24,633,539...24,644,875
JBrowse link
G Rpl11 ribosomal protein L11 affects expression ISO Benzbromarone affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 4:135,776,665...135,780,704
Ensembl chr 4:135,755,576...135,780,739
JBrowse link
G Rpl13 ribosomal protein L13 affects expression ISO Benzbromarone affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr 8:123,829,089...123,831,983
Ensembl chr 8:123,829,089...123,831,983
JBrowse link
G Rpl15 ribosomal protein L15 affects expression ISO Benzbromarone affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr14:4,198,710...4,201,873
Ensembl chr14:4,198,305...4,201,873
JBrowse link
G Rpl17 ribosomal protein L17 affects expression ISO Benzbromarone affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:75,132,049...75,136,455
Ensembl chr18:75,131,629...75,136,452
JBrowse link
G Rpl23 ribosomal protein L23 affects expression ISO Benzbromarone affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr11:97,668,352...97,673,265
Ensembl chr11:97,668,353...97,673,263
JBrowse link
G Rpl3 ribosomal protein L3 affects expression ISO Benzbromarone affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr15:79,961,993...79,967,553
Ensembl chr15:79,961,992...79,976,069
JBrowse link
G Rpl32 ribosomal protein L32 affects expression ISO Benzbromarone affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 6:115,782,475...115,785,704
Ensembl chr 6:115,782,466...115,785,708
JBrowse link
G Rpl4 ribosomal protein L4 affects expression ISO Benzbromarone affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 9:64,080,159...64,085,805
Ensembl chr 9:64,080,657...64,085,948
JBrowse link
G Rpn2 ribophorin II affects expression ISO Benzbromarone affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 2:157,121,018...157,168,238
Ensembl chr 2:157,120,937...157,168,239
JBrowse link
G Rps14 ribosomal protein S14 affects expression ISO Benzbromarone affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:60,907,668...60,911,618
Ensembl chr18:60,880,170...60,911,618
JBrowse link
G Rps18 ribosomal protein S18 affects expression ISO Benzbromarone affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr17:34,170,972...34,174,639
Ensembl chr17:34,170,973...34,174,975
JBrowse link
G Rps19 ribosomal protein S19 affects expression ISO Benzbromarone affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 7:24,584,013...24,589,236
Ensembl chr 7:24,583,796...24,589,231
JBrowse link
G Rps20 ribosomal protein S20 affects expression ISO Benzbromarone affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 4:3,831,334...3,835,600
Ensembl chr 4:3,831,334...3,835,665
JBrowse link
G Rps3a1 ribosomal protein S3A1 affects expression ISO Benzbromarone affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 3:86,045,247...86,049,975
Ensembl chr 3:86,045,247...86,050,009
JBrowse link
G Rps6 ribosomal protein S6 affects expression ISO Benzbromarone affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649
JBrowse link
G Rps8 ribosomal protein S8 affects expression ISO Benzbromarone affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 4:117,011,033...117,013,329
Ensembl chr 4:117,011,024...117,013,440
JBrowse link
G Rras2 related RAS viral (r-ras) oncogene 2 affects expression ISO Benzbromarone affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression ISO Benzbromarone affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression ISO Benzbromarone affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 1:15,924,086...15,962,946
Ensembl chr 1:15,924,086...15,962,946
JBrowse link
G Sdc2 syndecan 2 affects expression ISO Benzbromarone affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081
JBrowse link
G Sdhc succinate dehydrogenase complex, subunit C, integral membrane protein affects expression ISO Benzbromarone affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr 1:170,956,726...170,978,209
Ensembl chr 1:170,954,734...170,978,172
JBrowse link
G Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein affects expression ISO Benzbromarone affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 9:50,507,640...50,515,149
Ensembl chr 9:50,507,657...50,515,112
JBrowse link
G Serinc3 serine incorporator 3 affects expression ISO Benzbromarone affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 2:163,466,577...163,487,767
Ensembl chr 2:163,465,192...163,487,051
JBrowse link
G Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 affects expression ISO Benzbromarone affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr12:103,582,934...103,597,681
Ensembl chr12:103,581,045...103,597,703
JBrowse link
G Serpina4-ps1 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 affects expression ISO Benzbromarone affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983
JBrowse link
G Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 affects expression ISO Benzbromarone affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr11:75,322,562...75,330,327
Ensembl chr11:75,322,558...75,330,417
JBrowse link
G Sfxn1 sideroflexin 1 affects expression ISO Benzbromarone affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) affects expression ISO Benzbromarone affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr10:127,352,992...127,358,313
Ensembl chr10:127,352,992...127,358,313
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 affects expression ISO Benzbromarone affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 affects activity
multiple interactions
affects response to substance
decreases activity
ISO
EXP
Benzbromarone affects the activity of SLC22A12 protein
Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Oxypurinol]; Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
SLC22A12 protein affects the susceptibility to Benzbromarone
Benzbromarone inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid]
Benzbromarone results in decreased activity of SLC22A12 protein
CTD PMID:14694169 PMID:14747372 PMID:16135657 PMID:18670416 PMID:20486468 More... NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 multiple interactions ISO Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
JBrowse link
G Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 affects expression ISO Benzbromarone affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:35,747,657...35,762,900
Ensembl chr18:35,747,657...35,760,297
JBrowse link
G Slc25a13 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 affects expression ISO Benzbromarone affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 6:6,041,218...6,217,304
Ensembl chr 6:6,041,218...6,217,173
JBrowse link
G Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 affects expression ISO Benzbromarone affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr10:90,952,436...90,959,902
Ensembl chr10:90,952,436...90,959,921
JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 affects expression ISO Benzbromarone affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
JBrowse link
G Slc2a9 solute carrier family 2 (facilitated glucose transporter), member 9 multiple interactions EXP
ISO
Benzbromarone inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid]
Benzbromarone inhibits the reaction [SLC2A9 protein alternative form results in increased transport of Uric Acid]
CTD PMID:18842065 PMID:19587147 NCBI chr 5:38,506,616...38,660,488
Ensembl chr 5:38,506,616...38,660,486
JBrowse link
G Slc39a8 solute carrier family 39 (metal ion transporter), member 8 affects expression ISO Benzbromarone affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 3:135,522,644...135,594,333
Ensembl chr 3:135,531,040...135,594,333
JBrowse link
G Slc46a1 solute carrier family 46, member 1 affects expression ISO Benzbromarone affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr11:78,356,527...78,362,771
Ensembl chr11:78,356,523...78,362,885
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression ISO Benzbromarone affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:80,298,458...80,335,940
Ensembl chr18:80,296,507...80,335,940
JBrowse link
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 affects expression ISO Benzbromarone affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression ISO Benzbromarone results in increased expression of SOD2 mRNA CTD PMID:25108121 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sppl2a signal peptide peptidase like 2A affects expression ISO Benzbromarone affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 2:126,732,311...126,775,706
Ensembl chr 2:126,732,311...126,775,155
JBrowse link
G Srm spermidine synthase affects expression ISO Benzbromarone affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450
JBrowse link
G Srprb signal recognition particle receptor, B subunit affects expression ISO Benzbromarone affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 9:103,065,232...103,079,264
Ensembl chr 9:103,065,231...103,079,336
JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression ISO Benzbromarone affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 3:146,110,397...146,145,899
Ensembl chr 3:146,110,397...146,145,899
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression ISO Benzbromarone affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr16:58,290,105...58,344,614
Ensembl chr16:58,288,488...58,344,606
JBrowse link
G St6gal1 beta galactoside alpha 2,6 sialyltransferase 1 affects expression ISO Benzbromarone affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr16:23,043,478...23,179,100
Ensembl chr16:23,043,490...23,179,100
JBrowse link
G Suclg1 succinate-CoA ligase, GDP-forming, alpha subunit affects expression ISO Benzbromarone affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 6:73,225,488...73,253,890
Ensembl chr 6:73,225,365...73,253,894
JBrowse link
G Surf4 surfeit gene 4 affects expression ISO Benzbromarone affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 2:26,810,052...26,823,801
Ensembl chr 2:26,810,052...26,823,940
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression ISO Benzbromarone affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr12:81,538,968...81,579,685
Ensembl chr12:81,544,715...81,579,685
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression ISO Benzbromarone affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr13:56,757,399...56,787,172
Ensembl chr13:56,757,336...56,787,375
JBrowse link
G Thnsl2 threonine synthase-like 2 (bacterial) affects expression ISO Benzbromarone affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 6:71,105,150...71,121,364
Ensembl chr 6:71,105,150...71,121,423
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression ISO Benzbromarone affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:84,964,316...84,970,168
Ensembl chr18:84,964,316...84,969,649
JBrowse link
G Tkfc triokinase, FMN cyclase affects expression ISO Benzbromarone affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr19:10,565,153...10,583,257
Ensembl chr19:10,565,155...10,583,018
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression ISO Benzbromarone affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 1:74,327,406...74,343,495
Ensembl chr 1:74,327,406...74,344,781
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression ISO Benzbromarone affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr 1:167,136,239...167,161,547
Ensembl chr 1:167,135,947...167,161,547
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression ISO Benzbromarone affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr 5:124,678,835...124,688,566
Ensembl chr 5:124,678,758...124,688,569
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression ISO Benzbromarone affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:46,718,995...46,730,602
Ensembl chr18:46,693,302...46,730,602
JBrowse link
G Tmem123 transmembrane protein 123 affects expression ISO Benzbromarone affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 9:7,764,078...7,794,334
Ensembl chr 9:7,764,042...7,794,334
JBrowse link
G Tmem97 transmembrane protein 97 affects expression ISO Benzbromarone affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr11:78,432,643...78,441,561
Ensembl chr11:78,432,643...78,441,603
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO Benzbromarone results in increased expression of TNF protein
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD PMID:19362101 PMID:19933411 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Txn1 thioredoxin 1 affects expression ISO Benzbromarone affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression ISO Benzbromarone affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:63,795,872...63,825,535
Ensembl chr18:63,794,165...63,841,872
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression ISO Benzbromarone affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr 8:70,960,913...70,963,067
Ensembl chr 8:70,960,913...70,963,451
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression ISO Benzbromarone affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519
JBrowse link
G Ufd1 ubiquitin recognition factor in ER-associated degradation 1 affects expression ISO Benzbromarone affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr16:18,630,486...18,654,011
Ensembl chr16:18,630,529...18,654,011
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 affects expression ISO Benzbromarone affects the expression of UGT1A1 mRNA CTD PMID:19483382 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression ISO Benzbromarone affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr10:80,238,831...80,242,655
Ensembl chr10:80,238,831...80,242,664
JBrowse link
G Vnn1 vanin 1 affects expression ISO Benzbromarone affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
JBrowse link
G Wdr26 WD repeat domain 26 affects expression ISO Benzbromarone affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr 1:181,000,791...181,046,211
Ensembl chr 1:181,000,793...181,039,566
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide affects expression ISO Benzbromarone affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr 5:135,937,233...135,963,495
Ensembl chr 5:135,937,263...135,963,470
JBrowse link
G Zdhhc23 zinc finger, DHHC domain containing 23 affects expression ISO Benzbromarone affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr16:43,785,396...43,800,295
Ensembl chr16:43,785,396...43,800,154
JBrowse link
G Zp3r zona pellucida 3 receptor affects expression ISO Benzbromarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr 1:130,474,847...130,557,371
Ensembl chr 1:130,504,450...130,557,358
JBrowse link
G Zwint ZW10 interactor affects expression ISO Benzbromarone affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr10:72,490,678...72,510,796
Ensembl chr10:72,490,677...72,510,796
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      biological role 22178
        biochemical role 21449
          metabolite 21397
            marine metabolite 6941
              2,6-dibromophenol 345
                benzbromarone 338
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    p-block element atom 22120
                      carbon group element atom 21920
                        carbon atom 21846
                          organic molecular entity 21846
                            organic molecule 21662
                              organic cyclic compound 21269
                                carbocyclic compound 19701
                                  benzenoid aromatic compound 18846
                                    benzenes 18648
                                      bromobenzenes 4001
                                        bromophenol 1156
                                          dibromophenol 345
                                            2,6-dibromophenol 345
                                              benzbromarone 338
paths to the root