CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: benzbromarone
Accession: CHEBI:3023
browse the term
Definition: 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.
Synonyms: exact_synonym: (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
related_synonym: 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran; 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone; Formula=C17H12Br2O3; InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3; InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N; SMILES=CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1; Uroleap (TN)
xref: Beilstein:273668; CAS:3562-84-3; Drug_Central:318; KEGG:D01056; LINCS:LSM-2239
xref_mesh: MESH:D001553
xref: PMID:18636784; PMID:26693855; PMID:26792818; PMID:27391386; PMID:28131653; PMID:28166217; PMID:28202260; PMID:7661033
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Abcb11
ATP binding cassette subfamily B member 11
decreases activity multiple interactions
ISO
Benzbromarone results in decreased activity of ABCB11 protein Benzbromarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD
PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
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Abcb1a
ATP binding cassette subfamily B member 1A
affects expression
EXP
Benzbromarone affects the expression of ABCB1A mRNA
CTD
PMID:19483382
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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Abcb4
ATP binding cassette subfamily B member 4
decreases activity
ISO
Benzbromarone results in decreased activity of ABCB4 protein
CTD
PMID:28437613
NCBI chr 4:26,106,895...26,164,440
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Abcc1
ATP binding cassette subfamily C member 1
multiple interactions affects activity
ISO
Benzbromarone inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Benzbromarone inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin] Benzbromarone affects the activity of ABCC1 protein
CTD
PMID:9096673 PMID:9334814 PMID:15041471 PMID:16101123
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
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Abcc2
ATP binding cassette subfamily C member 2
multiple interactions decreases activity
EXP ISO
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD
PMID:19782883 PMID:19853032 PMID:22646477 PMID:31348918
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
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Abcc3
ATP binding cassette subfamily C member 3
multiple interactions
ISO
Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; yu ping feng san inhibits the reaction [Benzbromarone results in increased activity of ABCC3 protein]
CTD
PMID:31348918 PMID:34135758
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
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Abcc5
ATP binding cassette subfamily C member 5
multiple interactions
ISO
Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD
PMID:31348918
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
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Abcc6
ATP binding cassette subfamily C member 6
multiple interactions decreases activity affects expression
ISO EXP
Benzbromarone inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione] Benzbromarone results in decreased activity of ABCC6 protein Benzbromarone affects the expression of ABCC6 mRNA
CTD
PMID:11880368 PMID:14667841 PMID:19483382
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
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Abcg5
ATP binding cassette subfamily G member 5
affects expression
EXP
Benzbromarone affects the expression of ABCG5 mRNA
CTD
PMID:19483382
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
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Abhd1
abhydrolase domain containing 1
affects expression
EXP
Benzbromarone affects the expression of ABHD1 mRNA
CTD
PMID:19483382
NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464
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Abhd14b
abhydrolase domain containing 14b
affects expression
EXP
Benzbromarone affects the expression of ABHD14B mRNA
CTD
PMID:19483382
NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:115,965,932...115,970,833
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Abhd17a
abhydrolase domain containing 17A, depalmitoylase
affects expression
EXP
Benzbromarone affects the expression of ABHD17A mRNA
CTD
PMID:19483382
NCBI chr 7:9,775,016...9,781,447
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Acaca
acetyl-CoA carboxylase alpha
affects expression
EXP
Benzbromarone affects the expression of ACACA mRNA
CTD
PMID:19483382
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
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Acadl
acyl-CoA dehydrogenase, long chain
affects expression
EXP
Benzbromarone affects the expression of ACADL mRNA
CTD
PMID:19483382
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
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Ace2
angiotensin converting enzyme 2
decreases expression
ISO
Benzbromarone results in decreased expression of ACE2 mRNA
CTD
PMID:32808185
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596
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Aco1
aconitase 1
affects expression
EXP
Benzbromarone affects the expression of ACO1 mRNA
CTD
PMID:19483382
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
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Aco2
aconitase 2
affects expression
EXP
Benzbromarone affects the expression of ACO2 mRNA
CTD
PMID:19483382
NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
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Acot12
acyl-CoA thioesterase 12
affects expression
EXP
Benzbromarone affects the expression of ACOT12 mRNA
CTD
PMID:19483382
NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298
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Acot4
acyl-CoA thioesterase 4
affects expression
EXP
Benzbromarone affects the expression of ACOT4 mRNA
CTD
PMID:19483382
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
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Adam15
ADAM metallopeptidase domain 15
affects expression
EXP
Benzbromarone affects the expression of ADAM15 mRNA
CTD
PMID:19483382
NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
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Add1
adducin 1
affects expression
EXP
Benzbromarone affects the expression of ADD1 mRNA
CTD
PMID:19483382
NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
affects expression
EXP
Benzbromarone affects the expression of ADH4 mRNA
CTD
PMID:19483382
NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions increases expression
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [Benzbromarone results in increased expression of ADIPOQ mRNA] Benzbromarone results in increased expression of ADIPOQ protein
CTD
PMID:19048458 PMID:21329621
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
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Adtrp
androgen-dependent TFPI-regulating protein
affects expression
EXP
Benzbromarone affects the expression of ADTRP mRNA
CTD
PMID:19483382
NCBI chr17:23,113,578...23,199,616
Ensembl chr17:23,135,809...23,216,622
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Afm
afamin
affects expression
EXP
Benzbromarone affects the expression of AFM mRNA
CTD
PMID:19483382
NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039
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Agt
angiotensinogen
affects expression
EXP
Benzbromarone affects the expression of AGT mRNA
CTD
PMID:19483382
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
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Agtr1a
angiotensin II receptor, type 1a
affects expression
EXP
Benzbromarone affects the expression of AGTR1A mRNA
CTD
PMID:19483382
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
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Akr1a1
aldo-keto reductase family 1 member A1
affects expression
EXP
Benzbromarone affects the expression of AKR1A1 mRNA
CTD
PMID:19483382
NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
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Akr1b15
aldo-keto reductase family 1 member B15
decreases activity
EXP
Benzbromarone results in decreased activity of AKR1B8 protein
CTD
PMID:18845131
NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
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Akr1c1
aldo-keto reductase family 1, member C1
multiple interactions
ISO
Benzbromarone binds to and results in decreased activity of AKR1C1 protein
CTD
PMID:12604236
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
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Akr1c2
aldo-keto reductase family 1, member C2
decreases activity
ISO
Benzbromarone results in decreased activity of AKR1C2 protein
CTD
PMID:12604236
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
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Akr1c3
aldo-keto reductase family 1, member C3
decreases activity
ISO
Benzbromarone results in decreased activity of AKR1C3 protein
CTD
PMID:12604236
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
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Akr7a2
aldo-keto reductase family 7, member A2
affects expression
EXP
Benzbromarone affects the expression of AKR7A2 mRNA
CTD
PMID:19483382
NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109
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Akr7a3
aldo-keto reductase family 7 member A3
affects expression
EXP
Benzbromarone affects the expression of AKR7A3 mRNA
CTD
PMID:19483382
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Benzbromarone affects the expression of ALDH1A1 mRNA
CTD
PMID:19483382
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
affects expression
EXP
Benzbromarone affects the expression of ALDH1A7 mRNA
CTD
PMID:19483382
NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523
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Aldh2
aldehyde dehydrogenase 2 family member
affects expression
EXP
Benzbromarone affects the expression of ALDH2 mRNA
CTD
PMID:19483382
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
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Alkbh7
alkB homolog 7
affects expression
EXP
Benzbromarone affects the expression of ALKBH7 mRNA
CTD
PMID:19483382
NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048
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Ap2m1
adaptor related protein complex 2 subunit mu 1
affects expression
EXP
Benzbromarone affects the expression of AP2M1 mRNA
CTD
PMID:19483382
NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
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Apcs
amyloid P component, serum
affects expression
EXP
Benzbromarone affects the expression of APCS mRNA
CTD
PMID:19483382
NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
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Apoa4
apolipoprotein A4
affects expression
EXP
Benzbromarone affects the expression of APOA4 mRNA
CTD
PMID:19483382
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
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Apoh
apolipoprotein H
affects expression
EXP
Benzbromarone affects the expression of APOH mRNA
CTD
PMID:19483382
NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
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Apool
apolipoprotein O-like
affects expression
EXP
Benzbromarone affects the expression of APOOL mRNA
CTD
PMID:19483382
NCBI chr X:81,569,960...81,635,906
Ensembl chr X:81,570,053...81,640,036
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Arg1
arginase 1
affects expression
EXP
Benzbromarone affects the expression of ARG1 mRNA
CTD
PMID:19483382
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
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Arl6ip1
ARL6 interacting reticulophagy regulator 1
affects expression
EXP
Benzbromarone affects the expression of ARL6IP1 mRNA
CTD
PMID:19483382
NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232
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Asgr2
asialoglycoprotein receptor 2
affects expression
EXP
Benzbromarone affects the expression of ASGR2 mRNA
CTD
PMID:19483382
NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
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Atf5
activating transcription factor 5
affects expression
EXP
Benzbromarone affects the expression of ATF5 mRNA
CTD
PMID:19483382
NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
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Atp5f1e
ATP synthase F1 subunit epsilon
affects expression
EXP
Benzbromarone affects the expression of ATP5F1E mRNA
CTD
PMID:19483382
NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
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Atp6ap2
ATPase H+ transporting accessory protein 2
affects expression
EXP
Benzbromarone affects the expression of ATP6AP2 mRNA
CTD
PMID:19483382
NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875
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Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
Benzbromarone affects the expression of ATP6V1A mRNA
CTD
PMID:19483382
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
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Atp6v1f
ATPase H+ transporting V1 subunit F
affects expression
EXP
Benzbromarone affects the expression of ATP6V1F mRNA
CTD
PMID:19483382
NCBI chr 4:59,033,020...59,035,980
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Baat
bile acid CoA:amino acid N-acyltransferase
affects expression
EXP
Benzbromarone affects the expression of BAAT mRNA
CTD
PMID:19483382
NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181
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Bcl6b
BCL6B, transcription repressor
affects expression
EXP
Benzbromarone affects the expression of BCL6B mRNA
CTD
PMID:19483382
NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631
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Bltp3b
bridge-like lipid transfer protein family member 3B
affects expression
EXP
Benzbromarone affects the expression of BLTP3B mRNA
CTD
PMID:19483382
NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083
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Bmf
Bcl2 modifying factor
affects expression
EXP
Benzbromarone affects the expression of BMF mRNA
CTD
PMID:19483382
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
G
Bnip3
BCL2 interacting protein 3
affects expression
EXP
Benzbromarone affects the expression of BNIP3 mRNA
CTD
PMID:19483382
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
G
Btf3
basic transcription factor 3
affects expression
EXP
Benzbromarone affects the expression of BTF3 mRNA
CTD
PMID:19483382
NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125 Ensembl chr13:31,394,011...31,401,125
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C1qbp
complement C1q binding protein
affects expression
EXP
Benzbromarone affects the expression of C1QBP mRNA
CTD
PMID:19483382
NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235
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C1s
complement C1s
affects expression
EXP
Benzbromarone affects the expression of C1S mRNA
CTD
PMID:19483382
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
G
C2cd2
C2 calcium-dependent domain containing 2
affects expression
EXP
Benzbromarone affects the expression of C2CD2 mRNA
CTD
PMID:19483382
NCBI chr11:50,694,680...50,759,096
Ensembl chr11:50,694,563...50,759,016
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C4bpa
complement component 4 binding protein, alpha
affects expression
EXP
Benzbromarone affects the expression of C4BPA mRNA
CTD
PMID:19483382
NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471
G
C7
complement C7
affects expression
EXP
Benzbromarone affects the expression of C7 mRNA
CTD
PMID:19483382
NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672
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C8b
complement C8 beta chain
affects expression
EXP
Benzbromarone affects the expression of C8B mRNA
CTD
PMID:19483382
NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
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Ca3
carbonic anhydrase 3
affects expression
EXP
Benzbromarone affects the expression of CAR3 mRNA
CTD
PMID:19483382
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
G
Cadps2
calcium dependent secretion activator 2
affects expression
EXP
Benzbromarone affects the expression of CADPS2 mRNA
CTD
PMID:19483382
NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
G
Caprin1
cell cycle associated protein 1
affects expression
EXP
Benzbromarone affects the expression of CAPRIN1 mRNA
CTD
PMID:19483382
NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
G
Car2
carbonic anhydrase 2
affects expression
EXP
Benzbromarone affects the expression of CA2 mRNA
CTD
PMID:19483382
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
G
Casp3
caspase 3
affects expression
EXP
Benzbromarone affects the expression of CASP3 mRNA
CTD
PMID:19483382
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Cat
catalase
increases activity
EXP
Benzbromarone results in increased activity of CAT protein
CTD
PMID:2260096
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
G
Cbr1
carbonyl reductase 1
affects expression
EXP
Benzbromarone affects the expression of CBR1 mRNA
CTD
PMID:19483382
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
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Cd36
CD36 molecule
increases expression
ISO
Benzbromarone results in increased expression of CD36 mRNA
CTD
PMID:19048458
NCBI chr 4:18,209,088...18,302,142
G
Cdo1
cysteine dioxygenase type 1
affects expression
EXP
Benzbromarone affects the expression of CDO1 mRNA
CTD
PMID:19483382
NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
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Cept1
choline/ethanolamine phosphotransferase 1
affects expression
EXP
Benzbromarone affects the expression of CEPT1 mRNA
CTD
PMID:19483382
NCBI chr 2:196,682,455...196,724,430
Ensembl chr 2:196,681,681...196,723,812
G
Ces1d
carboxylesterase 1D
decreases activity
ISO
Benzbromarone results in decreased activity of CES1 protein
CTD
PMID:38670244
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
G
Ces2h
carboxylesterase 2H
affects expression decreases activity
EXP ISO
Benzbromarone affects the expression of CES2 mRNA Benzbromarone results in decreased activity of CES2 protein
CTD
PMID:19483382 PMID:38670244
NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
G
Cfi
complement factor I
affects expression
EXP
Benzbromarone affects the expression of CFI mRNA
CTD
PMID:19483382
NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786
G
Chp1
calcineurin-like EF-hand protein 1
affects expression
EXP
Benzbromarone affects the expression of CHP1 mRNA
CTD
PMID:19483382
NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443
G
Cisd1
CDGSH iron sulfur domain 1
affects expression
EXP
Benzbromarone affects the expression of CISD1 mRNA
CTD
PMID:19483382
NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042
G
Clcn4
chloride voltage-gated channel 4
affects expression
EXP
Benzbromarone affects the expression of CLCN4 mRNA
CTD
PMID:19483382
NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939
G
Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
affects expression
EXP
Benzbromarone affects the expression of CLPP mRNA
CTD
PMID:19483382
NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705
G
Clptm1l
CLPTM1-like
affects expression
EXP
Benzbromarone affects the expression of CLPTM1L mRNA
CTD
PMID:19483382
NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:31,496,094...31,512,077
G
Cmbl
carboxymethylenebutenolidase homolog
affects expression
EXP
Benzbromarone affects the expression of CMBL mRNA
CTD
PMID:19483382
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:84,242,512...84,301,880
G
Cmpk1
cytidine/uridine monophosphate kinase 1
affects expression
EXP
Benzbromarone affects the expression of CMPK1 mRNA
CTD
PMID:19483382
NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596
G
Copg1
COPI coat complex subunit gamma 1
affects expression
EXP
Benzbromarone affects the expression of COPG1 mRNA
CTD
PMID:19483382
NCBI chr 4:121,923,644...121,949,819
Ensembl chr 4:121,923,873...121,949,812
G
Cops4
COP9 signalosome subunit 4
affects expression
EXP
Benzbromarone affects the expression of COPS4 mRNA
CTD
PMID:19483382
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,382,900...9,413,107
G
Coq3
coenzyme Q3 methyltransferase
affects expression
EXP
Benzbromarone affects the expression of COQ3 mRNA
CTD
PMID:19483382
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:40,226,368...40,257,617
G
Cox4i1
cytochrome c oxidase subunit 4i1
affects expression
EXP
Benzbromarone affects the expression of COX4I1 mRNA
CTD
PMID:19483382
NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624
G
Cpn1
carboxypeptidase N subunit 1
affects expression
EXP
Benzbromarone affects the expression of CPN1 mRNA
CTD
PMID:19483382
NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
G
Cpq
carboxypeptidase Q
affects expression
EXP
Benzbromarone affects the expression of CPQ mRNA
CTD
PMID:19483382
NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
G
Cpt1a
carnitine palmitoyltransferase 1A
increases expression
ISO
Benzbromarone results in increased expression of CPT1A mRNA; Benzbromarone results in increased expression of CPT1A protein
CTD
PMID:25108121
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
G
Crem
cAMP responsive element modulator
affects expression
EXP
Benzbromarone affects the expression of CREM mRNA
CTD
PMID:19483382
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
G
Crp
C-reactive protein
multiple interactions decreases expression
ISO
Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein] Benzbromarone results in decreased expression of CRP protein
CTD
PMID:21329621
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
G
Csnk2b
casein kinase 2 beta
affects expression
EXP
Benzbromarone affects the expression of CSNK2B mRNA
CTD
PMID:19483382
NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
G
Csrp1
cysteine and glycine-rich protein 1
affects expression
EXP
Benzbromarone affects the expression of CSRP1 mRNA
CTD
PMID:19483382
NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139
G
Ctnna1
catenin alpha 1
affects expression
EXP
Benzbromarone affects the expression of CTNNA1 mRNA
CTD
PMID:19483382
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases activity
ISO
Benzbromarone results in decreased activity of CYP1A1 protein
CTD
PMID:33814510
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity
ISO
Benzbromarone results in decreased activity of CYP1B1 protein
CTD
PMID:33814510
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
G
Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP2A1 mRNA
CTD
PMID:19483382
NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
affects expression
EXP
Benzbromarone affects the expression of CYP2B2 mRNA
CTD
PMID:19483382
NCBI chr 1:90,722,243...90,736,272
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects expression
EXP
Benzbromarone affects the expression of CYP2B3 mRNA
CTD
PMID:19483382
NCBI chr 1:90,780,468...90,859,852
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
multiple interactions
ISO
Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein; Benzbromarone binds to and results in decreased activity of CYP2C19 protein
CTD
PMID:15615526
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
G
Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
affects expression
EXP
Benzbromarone affects the expression of CYP2D3 mRNA
CTD
PMID:19483382
NCBI chr 7:115,797,785...115,802,142
Ensembl chr 7:115,797,789...115,802,158
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2D4 mRNA
CTD
PMID:19483382
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
G
Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2F4 mRNA
CTD
PMID:19483382
NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
EXP
Benzbromarone affects the expression of CYP2J4 mRNA
CTD
PMID:19483382
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
G
Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP2T1 mRNA
CTD
PMID:19483382
NCBI chr 1:91,573,923...91,579,215
Ensembl chr 1:91,574,572...91,579,215
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
decreases activity
ISO
Benzbromarone results in decreased activity of CYP3A4 protein
CTD
PMID:39023798
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
G
Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
affects expression
EXP
Benzbromarone affects the expression of CYP3A23-3A1 mRNA
CTD
PMID:19483382
NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
G
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects expression
EXP
Benzbromarone affects the expression of CYP3A9 mRNA
CTD
PMID:19483382
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
G
Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
affects expression
EXP
Benzbromarone affects the expression of CYP4A8 mRNA
CTD
PMID:19483382
NCBI chr 5:133,938,882...133,970,226
Ensembl chr 5:133,938,883...133,970,226
G
Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
affects expression
EXP
Benzbromarone affects the expression of CYP4F6 mRNA
CTD
PMID:19483382
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
G
Dbi
diazepam binding inhibitor
affects expression
EXP
Benzbromarone affects the expression of DBI mRNA
CTD
PMID:19483382
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
G
Dcaf11
DDB1 and CUL4 associated factor 11
affects expression
EXP
Benzbromarone affects the expression of DCAF11 mRNA
CTD
PMID:19483382
NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672
G
Dcxr
dicarbonyl and L-xylulose reductase
affects expression
EXP
Benzbromarone affects the expression of DCXR mRNA
CTD
PMID:19483382
NCBI chr10:106,504,730...106,506,619
G
Decr1
2,4-dienoyl-CoA reductase 1
affects expression
EXP
Benzbromarone affects the expression of DECR1 mRNA
CTD
PMID:19483382
NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033
G
Dexi
Dexi homolog
affects expression
EXP
Benzbromarone affects the expression of DEXI mRNA
CTD
PMID:19483382
NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,632,961...5,645,648
G
Dgat1
diacylglycerol O-acyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of DGAT1 mRNA
CTD
PMID:19483382
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
G
Dhcr24
24-dehydrocholesterol reductase
affects expression
EXP
Benzbromarone affects the expression of DHCR24 mRNA
CTD
PMID:19483382
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
G
Dhrs4
dehydrogenase/reductase 4
affects expression
EXP
Benzbromarone affects the expression of DHRS4 mRNA
CTD
PMID:19483382
NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101
G
Dhrs7b
dehydrogenase/reductase 7B
affects expression
EXP
Benzbromarone affects the expression of DHRS7B mRNA
CTD
PMID:19483382
NCBI chr10:46,003,845...46,036,498
Ensembl chr10:46,003,845...46,036,499
G
Dhx16
DEAH-box helicase 16
affects expression
EXP
Benzbromarone affects the expression of DHX16 mRNA
CTD
PMID:19483382
NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,866,804...2,879,751
G
Dmac2l
distal membrane arm assembly component 2 like
affects expression
EXP
Benzbromarone affects the expression of DMAC2L mRNA
CTD
PMID:19483382
NCBI chr 6:93,941,605...93,959,932
Ensembl chr 6:93,941,690...93,960,662
G
Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
affects expression
EXP
Benzbromarone affects the expression of DNAJC3 mRNA
CTD
PMID:19483382
NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
G
Dpp4
dipeptidylpeptidase 4
affects expression
EXP
Benzbromarone affects the expression of DPP4 mRNA
CTD
PMID:19483382
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
G
Dpyd
dihydropyrimidine dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of DPYD mRNA
CTD
PMID:19483382
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
G
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
affects expression
EXP
Benzbromarone affects the expression of EARS2 mRNA
CTD
PMID:19483382
NCBI chr 1:186,025,740...186,057,165
G
Echs1
enoyl-CoA hydratase, short chain 1
affects expression
EXP
Benzbromarone affects the expression of ECHS1 mRNA
CTD
PMID:19483382
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
G
Eci1
enoyl-CoA delta isomerase 1
affects expression
EXP
Benzbromarone affects the expression of ECI1 mRNA
CTD
PMID:19483382
NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
G
Eci2
enoyl-CoA delta isomerase 2
affects expression
EXP
Benzbromarone affects the expression of ECI2 mRNA
CTD
PMID:19483382
NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
G
Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
Benzbromarone affects the expression of EEF1G mRNA
CTD
PMID:19483382
NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of EHHADH mRNA
CTD
PMID:19483382
NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
G
Eif4a2
eukaryotic translation initiation factor 4A2
affects expression
EXP
Benzbromarone affects the expression of EIF4A2 mRNA
CTD
PMID:19483382
NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
G
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
affects expression
EXP
Benzbromarone affects the expression of EIF4EBP1 mRNA
CTD
PMID:19483382
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
G
Eif4h
eukaryotic translation initiation factor 4H
affects expression
EXP
Benzbromarone affects the expression of EIF4H mRNA
CTD
PMID:19483382
NCBI chr12:27,719,527...27,736,350
Ensembl chr12:27,719,321...27,736,346
G
Enc1
ectodermal-neural cortex 1
affects expression
EXP
Benzbromarone affects the expression of ENC1 mRNA
CTD
PMID:19483382
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
G
Eno1
enolase 1
affects expression
EXP
Benzbromarone affects the expression of ENO1 mRNA
CTD
PMID:19483382
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
G
Enpep
glutamyl aminopeptidase
affects expression
EXP
Benzbromarone affects the expression of ENPEP mRNA
CTD
PMID:19483382
NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
G
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
affects expression
EXP
Benzbromarone affects the expression of ENPP1 mRNA
CTD
PMID:19483382
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
G
Epcam
epithelial cell adhesion molecule
affects expression
EXP
Benzbromarone affects the expression of EPCAM mRNA
CTD
PMID:19483382
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
G
Erp29
endoplasmic reticulum protein 29
affects expression
EXP
Benzbromarone affects the expression of ERP29 mRNA
CTD
PMID:19483382
NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
G
Esd
esterase D
affects expression
EXP
Benzbromarone affects the expression of ESD mRNA
CTD
PMID:19483382
NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508
G
Etfb
electron transfer flavoprotein subunit beta
affects expression
EXP
Benzbromarone affects the expression of ETFB mRNA
CTD
PMID:19483382
NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659
G
Eya2
EYA transcriptional coactivator and phosphatase 2
decreases activity
ISO
Benzbromarone results in decreased activity of EYA2 protein
CTD
PMID:22545090
NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:174,818,554...174,938,034
G
Eya3
EYA transcriptional coactivator and phosphatase 3
decreases activity
ISO
Benzbromarone results in decreased activity of EYA3 protein
CTD
PMID:22545090
NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:150,137,256...150,218,852
G
Faah
fatty acid amide hydrolase
affects expression
EXP
Benzbromarone affects the expression of FAAH mRNA
CTD
PMID:19483382
NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396
G
Fabp4
fatty acid binding protein 4
increases expression
ISO
Benzbromarone results in increased expression of FABP4 mRNA
CTD
PMID:19048458
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
G
Fads2
fatty acid desaturase 2
affects expression
EXP
Benzbromarone affects the expression of FADS2 mRNA
CTD
PMID:19483382
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
G
Fbp1
fructose-bisphosphatase 1
affects expression
EXP
Benzbromarone affects the expression of FBP1 mRNA
CTD
PMID:19483382
NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
affects expression
EXP
Benzbromarone affects the expression of FDFT1 mRNA
CTD
PMID:19483382
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
G
Fdps
farnesyl diphosphate synthase
affects expression
EXP
Benzbromarone affects the expression of FDPS mRNA
CTD
PMID:19483382
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
G
Fdx2
ferredoxin 2
affects expression
EXP
Benzbromarone affects the expression of FDX2 mRNA
CTD
PMID:19483382
NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
affects expression
EXP
Benzbromarone affects the expression of FMO1 mRNA
CTD
PMID:19483382
NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874
G
Gamt
guanidinoacetate N-methyltransferase
affects expression
EXP
Benzbromarone affects the expression of GAMT mRNA
CTD
PMID:19483382
NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of GAPDH mRNA
CTD
PMID:19483382
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
G
Gbe1
1,4-alpha-glucan branching enzyme 1
affects expression
EXP
Benzbromarone affects the expression of GBE1 mRNA
CTD
PMID:19483382
NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
G
Gchfr
GTP cyclohydrolase I feedback regulator
affects expression
EXP
Benzbromarone affects the expression of GCHFR mRNA
CTD
PMID:19483382
NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
G
Ggh
gamma-glutamyl hydrolase
affects expression
EXP
Benzbromarone affects the expression of GGH mRNA
CTD
PMID:19483382
NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647
G
Gjb1
gap junction protein, beta 1
affects expression
EXP
Benzbromarone affects the expression of GJB1 mRNA
CTD
PMID:19483382
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
G
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
affects expression
EXP
Benzbromarone affects the expression of GPLD1 mRNA
CTD
PMID:19483382
NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975
G
Gpx1
glutathione peroxidase 1
affects expression
EXP
Benzbromarone affects the expression of GPX1 mRNA
CTD
PMID:19483382
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx4
glutathione peroxidase 4
affects expression
EXP
Benzbromarone affects the expression of GPX4 mRNA
CTD
PMID:19483382
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
affects expression
EXP
Benzbromarone affects the expression of GRINA mRNA
CTD
PMID:19483382
NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042
G
Grpel1
GrpE-like 1, mitochondrial
affects expression
EXP
Benzbromarone affects the expression of GRPEL1 mRNA
CTD
PMID:19483382
NCBI chr14:78,517,049...78,522,868
Ensembl chr14:78,517,052...78,522,861
G
Gstt1
glutathione S-transferase theta 1
affects expression
EXP
Benzbromarone affects the expression of GSTT1 mRNA
CTD
PMID:19483382
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
G
Gtf2h5
general transcription factor IIH subunit 5
affects expression
EXP
Benzbromarone affects the expression of GTF2H5 mRNA
CTD
PMID:19483382
NCBI chr 1:49,061,904...49,068,612
Ensembl chr 1:49,061,959...49,070,039
G
Gulo
gulonolactone (L-) oxidase
affects expression
EXP
Benzbromarone affects the expression of GULO mRNA
CTD
PMID:19483382
NCBI chr15:40,205,677...40,227,766
Ensembl chr15:44,381,214...44,403,422
G
Gzma
granzyme A
affects expression
EXP
Benzbromarone affects the expression of GZMA mRNA
CTD
PMID:19483382
NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696
G
H3f3b
H3.3 histone B
affects expression
EXP
Benzbromarone affects the expression of H3F3B mRNA
CTD
PMID:19483382
NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636
G
Hal
histidine ammonia lyase
affects expression
EXP
Benzbromarone affects the expression of HAL mRNA
CTD
PMID:19483382
NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744
G
Hao2
hydroxyacid oxidase 2
affects expression
EXP
Benzbromarone affects the expression of HAO2 mRNA
CTD
PMID:19483382
NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133
G
Hba-a2
hemoglobin alpha, adult chain 2
affects expression
EXP
Benzbromarone affects the expression of HBA-A2 mRNA
CTD
PMID:19483382
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
G
Hbb
hemoglobin subunit beta
affects expression
EXP
Benzbromarone affects the expression of HBB mRNA
CTD
PMID:19483382
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
G
Hdc
histidine decarboxylase
affects expression
EXP
Benzbromarone affects the expression of HDC mRNA
CTD
PMID:19483382
NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
EXP
Benzbromarone affects the expression of HGD mRNA
CTD
PMID:19483382
NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
G
Hmgn1
high mobility group nucleosome binding domain 1
affects expression
EXP
Benzbromarone affects the expression of HMGN1 mRNA
CTD
PMID:19483382
NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of HPRT1 mRNA
CTD
PMID:19483382
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
G
Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
affects expression
EXP
Benzbromarone affects the expression of HPS5 mRNA
CTD
PMID:19483382
NCBI chr 1:106,417,902...106,457,220
Ensembl chr 1:106,417,902...106,452,859
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
EXP
Benzbromarone affects the expression of HSD17B4 mRNA
CTD
PMID:19483382
NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467
G
Hsdl2
hydroxysteroid dehydrogenase like 2
affects expression
EXP
Benzbromarone affects the expression of HSDL2 mRNA
CTD
PMID:19483382
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
G
Htra1
HtrA serine peptidase 1
affects expression
EXP
Benzbromarone affects the expression of HTRA1 mRNA
CTD
PMID:19483382
NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620
G
Igf1
insulin-like growth factor 1
affects expression
EXP
Benzbromarone affects the expression of IGF1 mRNA
CTD
PMID:19483382
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
G
Igfals
insulin-like growth factor binding protein, acid labile subunit
affects expression
EXP
Benzbromarone affects the expression of IGFALS mRNA
CTD
PMID:19483382
NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
G
Igfbp2
insulin-like growth factor binding protein 2
affects expression
EXP
Benzbromarone affects the expression of IGFBP2 mRNA
CTD
PMID:19483382
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
G
Il1a
interleukin 1 alpha
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
G
Il1b
interleukin 1 beta
multiple interactions
ISO
Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein]
CTD
PMID:21329621
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il6
interleukin 6
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Impa1
inositol monophosphatase 1
affects expression
EXP
Benzbromarone affects the expression of IMPA1 mRNA
CTD
PMID:19483382
NCBI chr 2:93,370,200...93,391,474
Ensembl chr 2:93,370,299...93,391,468
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Benzbromarone affects the expression of INHBE mRNA
CTD
PMID:19483382
NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519
G
Isyna1
inositol-3-phosphate synthase 1
affects expression
EXP
Benzbromarone affects the expression of ISYNA1 mRNA
CTD
PMID:19483382
NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955
G
Itih4
inter-alpha-trypsin inhibitor heavy chain 4
affects expression
EXP
Benzbromarone affects the expression of ITIH4 mRNA
CTD
PMID:19483382
NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160
G
Iyd
iodotyrosine deiodinase
decreases activity
ISO
Benzbromarone results in decreased activity of IYD protein
CTD
PMID:24012475
NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386
G
Jak1
Janus kinase 1
affects expression
EXP
Benzbromarone affects the expression of JAK1 mRNA
CTD
PMID:19483382
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
G
Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
affects expression
EXP
Benzbromarone affects the expression of KDELR2 mRNA
CTD
PMID:19483382
NCBI chr12:16,252,424...16,270,737
Ensembl chr12:16,252,424...16,270,719
G
Kdr
kinase insert domain receptor
affects expression
EXP
Benzbromarone affects the expression of KDR mRNA
CTD
PMID:19483382
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
G
Krt8
keratin 8
affects expression
EXP
Benzbromarone affects the expression of KRT8 mRNA
CTD
PMID:19483382
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
G
Lcat
lecithin cholesterol acyltransferase
affects expression
EXP
Benzbromarone affects the expression of LCAT mRNA
CTD
PMID:19483382
NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
G
Lcmt1
leucine carboxyl methyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of LCMT1 mRNA
CTD
PMID:19483382
NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:187,327,706...187,391,516
G
Lipc
lipase C, hepatic type
affects expression
EXP
Benzbromarone affects the expression of LIPC mRNA
CTD
PMID:19483382
NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285
G
Lox
lysyl oxidase
affects expression
EXP
Benzbromarone affects the expression of LOX mRNA
CTD
PMID:19483382
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
G
Lpl
lipoprotein lipase
increases expression
ISO
Benzbromarone results in increased expression of LPL protein
CTD
PMID:18274627
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
G
Lrp3
LDL receptor related protein 3
affects expression
EXP
Benzbromarone affects the expression of LRP3 mRNA
CTD
PMID:19483382
NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057
G
Man2b1
mannosidase, alpha, class 2B, member 1
affects expression
EXP
Benzbromarone affects the expression of MAN2B1 mRNA
CTD
PMID:19483382
NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246
G
Map2k2
mitogen activated protein kinase kinase 2
affects expression
EXP
Benzbromarone affects the expression of MAP2K2 mRNA
CTD
PMID:19483382
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
G
Masp2
MBL associated serine protease 2
affects expression
EXP
Benzbromarone affects the expression of MASP2 mRNA
CTD
PMID:19483382
NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705
G
Me1
malic enzyme 1
affects expression
EXP
Benzbromarone affects the expression of ME1 mRNA
CTD
PMID:19483382
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
G
Mmut
methylmalonyl-CoA mutase
affects expression
EXP
Benzbromarone affects the expression of MMUT mRNA
CTD
PMID:19483382
NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342
G
Mro
maestro
affects expression
EXP
Benzbromarone affects the expression of MRO mRNA
CTD
PMID:19483382
NCBI chr18:69,723,764...69,742,815
Ensembl chr18:69,725,798...69,743,031
G
Mrpl2
mitochondrial ribosomal protein L2
affects expression
EXP
Benzbromarone affects the expression of MRPL2 mRNA
CTD
PMID:19483382
NCBI chr 9:21,830,834...21,834,607
Ensembl chr 9:21,830,835...21,834,641
G
Mrpl9
mitochondrial ribosomal protein L9
affects expression
EXP
Benzbromarone affects the expression of MRPL9 mRNA
CTD
PMID:19483382
NCBI chr 2:184,768,837...184,775,787
Ensembl chr 2:184,763,529...184,775,777
G
Mug2
murinoglobulin 2
affects expression
EXP
Benzbromarone affects the expression of PZP mRNA
CTD
PMID:19483382
NCBI chr 4:156,836,140...156,908,972
G
Myadm
myeloid-associated differentiation marker
affects expression
EXP
Benzbromarone affects the expression of MYADM mRNA
CTD
PMID:19483382
NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710
G
Mycbp2
MYC binding protein 2
affects expression
EXP
Benzbromarone affects the expression of MYCBP2 mRNA
CTD
PMID:19483382
NCBI chr15:86,352,061...86,590,126
Ensembl chr15:86,352,061...86,590,325
G
Myo1d
myosin ID
affects expression
EXP
Benzbromarone affects the expression of MYO1D mRNA
CTD
PMID:19483382
NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,975,122...66,263,958
G
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
affects expression
EXP
Benzbromarone affects the expression of NAA38 mRNA
CTD
PMID:19483382
NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715
G
Nap1l1
nucleosome assembly protein 1-like 1
affects expression
EXP
Benzbromarone affects the expression of NAP1L1 mRNA
CTD
PMID:19483382
NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
G
Nat8
N-acetyltransferase 8
affects expression
EXP
Benzbromarone affects the expression of NAT8 mRNA
CTD
PMID:19483382
NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159
G
Ndrg2
NDRG family member 2
affects expression
EXP
Benzbromarone affects the expression of NDRG2 mRNA
CTD
PMID:19483382
NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125
G
Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
affects expression
EXP
Benzbromarone affects the expression of NDUFS5 mRNA
CTD
PMID:19483382
NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909 Ensembl chr 5:184,849,197...185,028,909 Ensembl chr14:184,849,197...185,028,909
G
Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
affects expression
EXP
Benzbromarone affects the expression of NDUFV3 mRNA
CTD
PMID:19483382
NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847 Ensembl chr20:48,468,224...48,488,847
G
Neu2
neuraminidase 2
affects expression
EXP
Benzbromarone affects the expression of NEU2 mRNA
CTD
PMID:19483382
NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:95,696,507...95,715,208
G
Nfx1
nuclear transcription factor, X-box binding 1
affects expression
EXP
Benzbromarone affects the expression of NFX1 mRNA
CTD
PMID:19483382
NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889
G
Nipal2
NIPA-like domain containing 2
affects expression
EXP
Benzbromarone affects the expression of NIPAL2 mRNA
CTD
PMID:19483382
NCBI chr 7:67,659,628...67,771,105
Ensembl chr 7:67,659,628...67,769,959
G
Nit1
nitrilase 1
affects expression
EXP
Benzbromarone affects the expression of NIT1 mRNA
CTD
PMID:19483382
NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Benzbromarone affects the expression of NME2 mRNA
CTD
PMID:19483382
NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497 Ensembl chr10:11,179,066...11,179,497
G
Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects expression
EXP
Benzbromarone affects the expression of NR1I3 mRNA
CTD
PMID:19483382
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
Benzbromarone affects the expression of NR3C1 mRNA
CTD
PMID:19483382
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
G
Oaf
out at first homolog
affects expression
EXP
Benzbromarone affects the expression of OAF mRNA
CTD
PMID:19483382
NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
G
Obp3
alpha-2u globulin PGCL4
affects expression
EXP
Benzbromarone affects the expression of OBP3 mRNA
CTD
PMID:19483382
NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675
G
Ogdh
oxoglutarate dehydrogenase
affects expression
EXP
Benzbromarone affects the expression of OGDH mRNA
CTD
PMID:19483382
NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271
G
Olr59
olfactory receptor 59
affects expression
EXP
Benzbromarone affects the expression of OLR59 mRNA
CTD
PMID:19483382
NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265
G
Ostc
oligosaccharyltransferase complex non-catalytic subunit
affects expression
EXP
Benzbromarone affects the expression of OSTC mRNA
CTD
PMID:19483382
NCBI chr 2:221,924,727...221,940,253
Ensembl chr 2:221,874,948...221,940,267
G
Otc
ornithine transcarbamylase
affects expression
EXP
Benzbromarone affects the expression of OTC mRNA
CTD
PMID:19483382
NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555
G
Pabpc4
poly(A) binding protein, cytoplasmic 4
affects expression
EXP
Benzbromarone affects the expression of PABPC4 mRNA
CTD
PMID:19483382
NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087
G
Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
EXP
Benzbromarone affects the expression of PAICS mRNA
CTD
PMID:19483382
NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027
G
Pc
pyruvate carboxylase
affects expression
EXP
Benzbromarone affects the expression of PCX mRNA
CTD
PMID:19483382
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
G
Pccb
propionyl-CoA carboxylase subunit beta
affects expression
EXP
Benzbromarone affects the expression of PCCB mRNA
CTD
PMID:19483382
NCBI chr 8:110,470,197...110,520,222
Ensembl chr 8:110,469,934...110,520,187
G
Pcsk6
proprotein convertase subtilisin/kexin type 6
affects expression
EXP
Benzbromarone affects the expression of PCSK6 mRNA
CTD
PMID:19483382
NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128
G
Pctp
phosphatidylcholine transfer protein
affects expression
EXP
Benzbromarone affects the expression of PCTP mRNA
CTD
PMID:19483382
NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432
G
Pdcl3
phosducin-like 3
affects expression
EXP
Benzbromarone affects the expression of PDCL3 mRNA
CTD
PMID:19483382
NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529
G
Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Benzbromarone affects the expression of PDIA3 mRNA
CTD
PMID:19483382
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
G
Pdia6
protein disulfide isomerase family A, member 6
affects expression
EXP
Benzbromarone affects the expression of PDIA6 mRNA
CTD
PMID:19483382
NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091
G
Pex19
peroxisomal biogenesis factor 19
affects expression
EXP
Benzbromarone affects the expression of PEX19 mRNA
CTD
PMID:19483382
NCBI chr13:87,124,654...87,141,170
Ensembl chr13:87,124,698...87,141,757
G
Pgam1
phosphoglycerate mutase 1
affects expression
EXP
Benzbromarone affects the expression of PGAM1 mRNA
CTD
PMID:19483382
NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
G
Pgrmc1
progesterone receptor membrane component 1
affects expression
EXP
Benzbromarone affects the expression of PGRMC1 mRNA
CTD
PMID:19483382
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
G
Phyh
phytanoyl-CoA 2-hydroxylase
affects expression
EXP
Benzbromarone affects the expression of PHYH mRNA
CTD
PMID:19483382
NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645
G
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
affects expression
EXP
Benzbromarone affects the expression of PIGP mRNA
CTD
PMID:19483382
NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082
G
Pklr
pyruvate kinase L/R
affects expression
EXP
Benzbromarone affects the expression of PKLR mRNA
CTD
PMID:19483382
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
G
Plbd1
phospholipase B domain containing 1
affects expression
EXP
Benzbromarone affects the expression of PLBD1 mRNA
CTD
PMID:19483382
NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488
G
Plg
plasminogen
affects expression
EXP
Benzbromarone affects the expression of PLG mRNA
CTD
PMID:19483382
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320
G
Pls3
plastin 3
affects expression
EXP
Benzbromarone affects the expression of PLS3 mRNA
CTD
PMID:19483382
NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893
G
Pon2
paraoxonase 2
affects expression
EXP
Benzbromarone affects the expression of PON2 mRNA
CTD
PMID:19483382
NCBI chr 4:34,356,270...34,391,684
Ensembl chr 4:34,356,274...34,391,996
G
Pparg
peroxisome proliferator-activated receptor gamma
affects expression
ISO
Benzbromarone affects the expression of PPARG mRNA
CTD
PMID:19048458
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
EXP
Benzbromarone affects the expression of PPDPF mRNA
CTD
PMID:19483382
NCBI chr 3:188,676,821...188,678,599
Ensembl chr 3:188,676,965...188,678,599
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Prdx2
peroxiredoxin 2
affects expression
EXP
Benzbromarone affects the expression of PRDX2 mRNA
CTD
PMID:19483382
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
G
Prdx6
peroxiredoxin 6
affects expression
EXP
Benzbromarone affects the expression of PRDX6 mRNA
CTD
PMID:19483382
NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657
G
Proc
protein C, inactivator of coagulation factors Va and VIIIa
affects expression
EXP
Benzbromarone affects the expression of PROC mRNA
CTD
PMID:19483382
NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964
G
Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
affects expression
EXP
Benzbromarone affects the expression of PRPSAP1 mRNA
CTD
PMID:19483382
NCBI chr10:102,199,949...102,221,642
Ensembl chr10:102,199,950...102,221,642
G
Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
Benzbromarone affects the expression of PSMA6 mRNA
CTD
PMID:19483382
NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717
G
Psmb1
proteasome 20S subunit beta 1
affects expression
EXP
Benzbromarone affects the expression of PSMB1 mRNA
CTD
PMID:19483382
NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
G
Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
Benzbromarone affects the expression of PSMB3 mRNA
CTD
PMID:19483382
NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
G
Psmc1
proteasome 26S subunit, ATPase 1
affects expression
EXP
Benzbromarone affects the expression of PSMC1 mRNA
CTD
PMID:19483382
NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858
G
Psmc3
proteasome 26S subunit, ATPase 3
affects expression
EXP
Benzbromarone affects the expression of PSMC3 mRNA
CTD
PMID:19483382
NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176
G
Psmc5
proteasome 26S subunit, ATPase 5
affects expression
EXP
Benzbromarone affects the expression of PSMC5 mRNA
CTD
PMID:19483382
NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
G
Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Benzbromarone affects the expression of PSMD1 mRNA
CTD
PMID:19483382
NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
G
Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
affects expression
EXP
Benzbromarone affects the expression of PSMD4 mRNA
CTD
PMID:19483382
NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201
G
Ptms
parathymosin
affects expression
EXP
Benzbromarone affects the expression of PTMS mRNA
CTD
PMID:19483382
NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Benzbromarone affects the expression of PTPRF mRNA
CTD
PMID:19483382
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
G
Pttg1ip
PTTG1 interacting protein
affects expression
EXP
Benzbromarone affects the expression of PTTG1IP mRNA
CTD
PMID:19483382
NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,029,608...11,046,909
G
Pygl
glycogen phosphorylase L
affects expression
EXP
Benzbromarone affects the expression of PYGL mRNA
CTD
PMID:19483382
NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269
G
Rab5if
RAB5 interacting factor
affects expression
EXP
Benzbromarone affects the expression of RAB5IF mRNA
CTD
PMID:19483382
NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067
G
Rida
reactive intermediate imine deaminase A homolog
affects expression
EXP
Benzbromarone affects the expression of RIDA mRNA
CTD
PMID:19483382
NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692
G
Rnase4
ribonuclease A family member 4
affects expression
EXP
Benzbromarone affects the expression of RNASE4 mRNA
CTD
PMID:19483382
NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
G
Rnf103
ring finger protein 103
affects expression
EXP
Benzbromarone affects the expression of RNF103 mRNA
CTD
PMID:19483382
NCBI chr 4:105,084,762...105,100,839
Ensembl chr 4:105,084,686...105,106,809
G
Rnps1
RNA binding protein with serine rich domain 1
affects expression
EXP
Benzbromarone affects the expression of RNPS1 mRNA
CTD
PMID:19483382
NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393
G
Rpl11
ribosomal protein L11
affects expression
EXP
Benzbromarone affects the expression of RPL11 mRNA
CTD
PMID:19483382
NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:153,557,597...153,561,127
G
Rpl13
ribosomal protein L13
affects expression
EXP
Benzbromarone affects the expression of RPL13 mRNA
CTD
PMID:19483382
NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
G
Rpl15
ribosomal protein L15
affects expression
EXP
Benzbromarone affects the expression of RPL15 mRNA
CTD
PMID:19483382
NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
G
Rpl17
ribosomal protein L17
affects expression
EXP
Benzbromarone affects the expression of RPL17 mRNA
CTD
PMID:19483382
NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638 Ensembl chr18:111,722,010...111,722,638
G
Rpl23
ribosomal protein L23
affects expression
EXP
Benzbromarone affects the expression of RPL23 mRNA
CTD
PMID:19483382
NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
G
Rpl3
ribosomal protein L3
affects expression
EXP
Benzbromarone affects the expression of RPL3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990
G
Rpl32
ribosomal protein L32
affects expression
EXP
Benzbromarone affects the expression of RPL32 mRNA
CTD
PMID:19483382
NCBI chr 4:150,536,650...150,540,214
Ensembl chr 4:150,536,646...150,540,214
G
Rpl4
ribosomal protein L4
affects expression
EXP
Benzbromarone affects the expression of RPL4 mRNA
CTD
PMID:19483382
NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
G
Rpn2
ribophorin II
affects expression
EXP
Benzbromarone affects the expression of RPN2 mRNA
CTD
PMID:19483382
NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:166,362,049...166,409,922
G
Rps14
ribosomal protein S14
affects expression
EXP
Benzbromarone affects the expression of RPS14 mRNA
CTD
PMID:19483382
NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
G
Rps18
ribosomal protein S18
affects expression
EXP
Benzbromarone affects the expression of RPS18 mRNA
CTD
PMID:19483382
NCBI chr20:4,933,741...4,937,423
Ensembl chr20:4,917,095...4,937,423
G
Rps19
ribosomal protein S19
affects expression
EXP
Benzbromarone affects the expression of RPS19 mRNA
CTD
PMID:19483382
NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132 Ensembl chr 1:104,324,520...104,325,132
G
Rps20
ribosomal protein S20
affects expression
EXP
Benzbromarone affects the expression of RPS20 mRNA
CTD
PMID:19483382
NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621 Ensembl chr 9:42,839,965...43,095,621 Ensembl chr 5:42,839,965...43,095,621
G
Rps3a
ribosomal protein S3a
affects expression
EXP
Benzbromarone affects the expression of RPS3A mRNA
CTD
PMID:19483382
NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
G
Rps6
ribosomal protein S6
affects expression
EXP
Benzbromarone affects the expression of RPS6 mRNA
CTD
PMID:19483382
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
G
Rps8
ribosomal protein S8
affects expression
EXP
Benzbromarone affects the expression of RPS8 mRNA
CTD
PMID:19483382
NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548
G
Rras2
RAS related 2
affects expression
EXP
Benzbromarone affects the expression of RRAS2 mRNA
CTD
PMID:19483382
NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551
G
RT1-S3
RT1 class Ib, locus S3
affects expression
EXP
Benzbromarone affects the expression of RT1-S3 mRNA
CTD
PMID:19483382
NCBI chr20:2,675,463...2,680,229
G
S1pr1
sphingosine-1-phosphate receptor 1
affects expression
EXP
Benzbromarone affects the expression of S1PR1 mRNA
CTD
PMID:19483382
NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689
G
Sbspon
somatomedin B and thrombospondin, type 1 domain containing
affects expression
EXP
Benzbromarone affects the expression of SBSPON mRNA
CTD
PMID:19483382
NCBI chr 5:8,186,004...8,216,576
Ensembl chr 5:8,185,985...8,218,898
G
Sdc2
syndecan 2
affects expression
EXP
Benzbromarone affects the expression of SDC2 mRNA
CTD
PMID:19483382
NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294
G
Sdhc
succinate dehydrogenase complex subunit C
affects expression
EXP
Benzbromarone affects the expression of SDHC mRNA
CTD
PMID:19483382
NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044
G
Sdhd
succinate dehydrogenase complex subunit D
affects expression
EXP
Benzbromarone affects the expression of SDHD mRNA
CTD
PMID:19483382
NCBI chr 8:59,841,090...59,850,641
Ensembl chr 8:59,841,090...59,850,641
G
Serinc3
serine incorporator 3
affects expression
EXP
Benzbromarone affects the expression of SERINC3 mRNA
CTD
PMID:19483382
NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765
G
Serpina1
serpin family A member 1
affects expression
EXP
Benzbromarone affects the expression of SERPINA1 mRNA
CTD
PMID:19483382
NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
G
Serpina10
serpin family A member 10
affects expression
EXP
Benzbromarone affects the expression of SERPINA10 mRNA
CTD
PMID:19483382
NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:128,520,896...128,529,332
G
Serpina4
serpin family A member 4
affects expression
EXP
Benzbromarone affects the expression of SERPINA4 mRNA
CTD
PMID:19483382
NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028
G
Serpinf2
serpin family F member 2
affects expression
EXP
Benzbromarone affects the expression of SERPINF2 mRNA
CTD
PMID:19483382
NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996
G
Sfxn1
sideroflexin 1
affects expression
EXP
Benzbromarone affects the expression of SFXN1 mRNA
CTD
PMID:19483382
NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456
G
Shmt2
serine hydroxymethyltransferase 2
affects expression
EXP
Benzbromarone affects the expression of SHMT2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC22A1 mRNA
CTD
PMID:19483382
NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
G
Slc22a12
solute carrier family 22 member 12
affects activity multiple interactions affects response to substance decreases activity
ISO EXP
Benzbromarone affects the activity of SLC22A12 protein Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Oxypurinol]; Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] SLC22A12 protein affects the susceptibility to Benzbromarone Benzbromarone inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid] Benzbromarone results in decreased activity of SLC22A12 protein
CTD
PMID:14694169 PMID:14747372 PMID:16135657 PMID:18670416 PMID:20486468 PMID:21074513 PMID:21272127 PMID:21449597 More...
NCBI chr 1:213,274,266...213,282,793
Ensembl chr 1:213,274,275...213,281,380
G
Slc22a6
solute carrier family 22 member 6
multiple interactions
ISO
Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid]
CTD
PMID:12472777
NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311
G
Slc23a1
solute carrier family 23 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC23A1 mRNA
CTD
PMID:19483382
NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702
G
Slc25a13
solute carrier family 25 member 13
affects expression
EXP
Benzbromarone affects the expression of SLC25A13 mRNA
CTD
PMID:19483382
NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:35,145,721...35,328,360
G
Slc25a3
solute carrier family 25 member 3
affects expression
EXP
Benzbromarone affects the expression of SLC25A3 mRNA
CTD
PMID:19483382
NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309
G
Slc27a2
solute carrier family 27 member 2
affects expression
EXP
Benzbromarone affects the expression of SLC27A2 mRNA
CTD
PMID:19483382
NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581
G
Slc2a9
solute carrier family 2 member 9
multiple interactions
ISO
Benzbromarone inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid] Benzbromarone inhibits the reaction [SLC2A9 protein alternative form results in increased transport of Uric Acid]
CTD
PMID:18842065 PMID:19587147
NCBI chr14:76,540,649...76,674,277
Ensembl chr14:76,540,571...76,674,277
G
Slc39a8
solute carrier family 39 member 8
affects expression
EXP
Benzbromarone affects the expression of SLC39A8 mRNA
CTD
PMID:19483382
NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667
G
Slc46a1
solute carrier family 46 member 1
affects expression
EXP
Benzbromarone affects the expression of SLC46A1 mRNA
CTD
PMID:19483382
NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
G
Slc66a2
solute carrier family 66 member 2
affects expression
EXP
Benzbromarone affects the expression of SLC66A2 mRNA
CTD
PMID:19483382
NCBI chr18:75,976,000...76,014,651
Ensembl chr18:75,977,458...76,014,651
G
Slc6a6
solute carrier family 6 member 6
affects expression
EXP
Benzbromarone affects the expression of SLC6A6 mRNA
CTD
PMID:19483382
NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032
G
Slco1a1
solute carrier organic anion transporter family, member 1a1
affects expression
EXP
Benzbromarone affects the expression of SLCO1A1 mRNA
CTD
PMID:19483382
NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992
G
Sod2
superoxide dismutase 2
increases expression
ISO
Benzbromarone results in increased expression of SOD2 mRNA
CTD
PMID:25108121
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
G
Sppl2a
signal peptide peptidase-like 2A
affects expression
EXP
Benzbromarone affects the expression of SPPL2A mRNA
CTD
PMID:19483382
NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:134,605,750...134,646,752
G
Srm
spermidine synthase
affects expression
EXP
Benzbromarone affects the expression of SRM mRNA
CTD
PMID:19483382
NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705
G
Srprb
SRP receptor subunit beta
affects expression
EXP
Benzbromarone affects the expression of SRPRB mRNA
CTD
PMID:19483382
NCBI chr 8:103,768,685...103,782,632
G
Ssx2ip
SSX family member 2 interacting protein
affects expression
EXP
Benzbromarone affects the expression of SSX2IP mRNA
CTD
PMID:19483382
NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017
G
St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
EXP
Benzbromarone affects the expression of ST3GAL6 mRNA
CTD
PMID:19483382
NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720
G
St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
affects expression
EXP
Benzbromarone affects the expression of ST6GAL1 mRNA
CTD
PMID:19483382
NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
G
Suclg1
succinate-CoA ligase GDP/ADP-forming subunit alpha
affects expression
EXP
Benzbromarone affects the expression of SUCLG1 mRNA
CTD
PMID:19483382
NCBI chr 4:106,866,329...106,895,686
Ensembl chr 4:106,866,114...106,895,689
G
Surf4
surfeit 4
affects expression
EXP
Benzbromarone affects the expression of SURF4 mRNA
CTD
PMID:19483382
NCBI chr 3:30,646,435...30,659,641
Ensembl chr 3:30,638,299...30,661,390
G
Synj2bp
synaptojanin 2 binding protein
affects expression
EXP
Benzbromarone affects the expression of SYNJ2BP mRNA
CTD
PMID:19483382
NCBI chr 6:106,920,970...106,958,653
Ensembl chr 6:106,920,970...106,966,543
G
Tgfbi
transforming growth factor, beta induced
affects expression
EXP
Benzbromarone affects the expression of TGFBI mRNA
CTD
PMID:19483382
NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471
G
Thnsl2
threonine synthase-like 2
affects expression
EXP
Benzbromarone affects the expression of THNSL2 mRNA
CTD
PMID:19483382
NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959
G
Timm21
translocase of inner mitochondrial membrane 21
affects expression
EXP
Benzbromarone affects the expression of TIMM21 mRNA
CTD
PMID:19483382
NCBI chr18:80,589,775...80,594,237
Ensembl chr18:80,589,783...80,594,237
G
Tkfc
triokinase and FMN cyclase
affects expression
EXP
Benzbromarone affects the expression of TKFC mRNA
CTD
PMID:19483382
NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
G
Tmbim1
transmembrane BAX inhibitor motif containing 1
affects expression
EXP
Benzbromarone affects the expression of TMBIM1 mRNA
CTD
PMID:19483382
NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657
G
Tmbim6
transmembrane BAX inhibitor motif containing 6
affects expression
EXP
Benzbromarone affects the expression of TEGT mRNA
CTD
PMID:19483382
NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
G
Tmco1
transmembrane and coiled-coil domains 1
affects expression
EXP
Benzbromarone affects the expression of TMCO1 mRNA
CTD
PMID:19483382
NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201
G
Tmed2
transmembrane p24 trafficking protein 2
affects expression
EXP
Benzbromarone affects the expression of TMED2 mRNA
CTD
PMID:19483382
NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606
G
Tmed7
transmembrane p24 trafficking protein 7
affects expression
EXP
Benzbromarone affects the expression of TMED7 mRNA
CTD
PMID:19483382
NCBI chr18:41,505,167...41,512,243
Ensembl chr18:41,478,539...41,512,243
G
Tmem123
transmembrane protein 123
affects expression
EXP
Benzbromarone affects the expression of TMEM123 mRNA
CTD
PMID:19483382
NCBI chr 8:13,206,907...13,237,069
Ensembl chr 8:13,206,403...13,257,427
G
Tmem97
transmembrane protein 97
affects expression
EXP
Benzbromarone affects the expression of TMEM97 mRNA
CTD
PMID:19483382
NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818
G
Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
Benzbromarone results in increased expression of TNF protein [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD
PMID:19362101 PMID:19933411
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Txn1
thioredoxin 1
affects expression
EXP
Benzbromarone affects the expression of TXN1 mRNA
CTD
PMID:19483382
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
G
Txnl1
thioredoxin-like 1
affects expression
EXP
Benzbromarone affects the expression of TXNL1 mRNA
CTD
PMID:19483382
NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518
G
Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
affects expression
EXP
Benzbromarone affects the expression of UBA52 mRNA
CTD
PMID:19483382
NCBI chr16:18,952,583...18,954,780
G
Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
Benzbromarone affects the expression of UBE2N mRNA
CTD
PMID:19483382
NCBI chr 7:32,041,190...32,071,252
G
Ufd1
ubiquitin recognition factor in ER associated degradation 1
affects expression
EXP
Benzbromarone affects the expression of UFD1 mRNA
CTD
PMID:19483382
NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
affects expression
EXP
Benzbromarone affects the expression of UGT1A1 mRNA
CTD
PMID:19483382
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
G
Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
affects expression
EXP
Benzbromarone affects the expression of UQCR11 mRNA
CTD
PMID:19483382
NCBI chr 7:9,955,717...9,960,432
Ensembl chr 7:9,955,764...9,959,047
G
Vnn1
vanin 1
affects expression
EXP
Benzbromarone affects the expression of VNN1 mRNA
CTD
PMID:19483382
NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629
G
Wdr26
WD repeat domain 26
affects expression
EXP
Benzbromarone affects the expression of WDR26 mRNA
CTD
PMID:19483382
NCBI chr13:95,462,017...95,503,826
Ensembl chr13:95,462,020...95,503,738
G
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
Benzbromarone affects the expression of YWHAG mRNA
CTD
PMID:19483382
NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465
G
Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Benzbromarone affects the expression of ZDHHC23 mRNA
CTD
PMID:19483382
NCBI chr11:70,224,581...70,240,971
Ensembl chr11:70,225,045...70,240,102
G
Zwint
ZW10 interacting kinetochore protein
affects expression
EXP
Benzbromarone affects the expression of ZWINT mRNA
CTD
PMID:19483382
NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203
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