CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: kaempferol 3-O-beta-D-glucoside
Accession: CHEBI:30200
browse the term
Definition: A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage.
Synonyms: exact_synonym: 3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
related_synonym: 3,4',5,7-Tetrahydroxyflavone-3-glucoside; 4H-1-Benzopyran-4-one, 3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl beta-D-glucopyranoside; Astragalin; Formula=C21H20O11; InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2/t13-,15-,17+,18-,21+/m1/s1; InChIKey=JPUKWEQWGBDDQB-QSOFNFLRSA-N; Kaempferol 3-O-glucoside; SMILES=C1(=C(C(C2=C(C=C(C=C2O1)O)O)=O)O[C@H]3[C@H](O)[C@H]([C@@H]([C@@H](CO)O3)O)O)C=4C=CC(O)=CC4; astragaline; kaempferol-3-O-beta-glucopyranoside
alt_id: CHEBI:132836; CHEBI:31745
xref: CAS:480-10-4; HMDB:HMDB0037429; KEGG:C12249; KNApSAcK:C00005138; LIPID_MAPS_instance:LMPK12111725
xref_mesh: MESH:C001579
xref: MetaCyc:CPD1F-453; PMID:21329934; PMID:21466157; PMID:22210036; PMID:22489129; PMID:22766709; Reaxys:1359980; Wikipedia:Astragalin
cyclic_relationship: is_conjugate_acid_of CHEBI:169942
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD
PMID:22210036
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl3
C-C motif chemokine ligand 3
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA]
CTD
PMID:22210036
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
G
Il1b
interleukin 1 beta
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD
PMID:22210036
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD
PMID:22210036
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]
CTD
PMID:22210036
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:22210036
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD
PMID:22210036
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
CTD
PMID:22210036
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Tnf
tumor necrosis factor
multiple interactions
ISO
astragalin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD
PMID:22210036
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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