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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lithium atom
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Accession:CHEBI:30145 term browser browse the term
Definition:An alkali metal atom that has formula Li.
Synonyms:related_synonym: 3Li;   Formula=Li;   InChI=1S/Li;   InChIKey=WHXSMMKQMYFTQS-UHFFFAOYSA-N;   Li;   SMILES=[Li];   lithium;   litio
 xref: CAS:7439-93-2
 xref_mesh: MESH:D008094
 xref: WebElements:Li



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lithium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA] CTD PMID:19149911 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP Lithium results in increased expression of ABCB1B mRNA; Lithium results in increased expression of ABCB1B protein CTD PMID:19570321 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA] CTD PMID:19149911 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Actb actin, beta increases expression EXP Lithium results in increased expression of ACTB protein CTD PMID:18296634 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actr3 actin related protein 3 increases expression EXP Lithium results in increased expression of ACTR3 protein CTD PMID:18296634 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
G Adk adenosine kinase increases expression EXP Lithium results in increased expression of ADK protein CTD PMID:18296634 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Adnp2 ADNP homeobox 2 increases expression ISO Lithium results in increased expression of ADNP2 mRNA CTD PMID:19949822 NCBI chr18:73,571,870...73,597,088
Ensembl chr18:73,571,936...73,628,484
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
increases phosphorylation
ISO Lithium results in increased expression of AKT1 mRNA; Lithium results in increased expression of AKT1 protein
Lithium results in increased phosphorylation of AKT1 protein
CTD PMID:19440698 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression EXP Lithium results in decreased expression of ALDH1A3 protein CTD PMID:18296634 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 increases expression ISO Lithium results in increased expression of ANTXR2 mRNA CTD PMID:21092101 NCBI chr14:11,542,266...11,682,112
Ensembl chr14:11,541,772...11,682,094
JBrowse link
G Anxa2 annexin A2 decreases expression EXP Lithium results in decreased expression of ANXA2 protein CTD PMID:18296634 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa4 annexin A4 increases expression EXP Lithium results in increased expression of ANXA4 protein CTD PMID:18296634 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa5 annexin A5 increases expression EXP Lithium results in increased expression of ANXA5 protein CTD PMID:18296634 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO
EXP
Lithium inhibits the reaction [APP protein binds to APP protein]
Lithium inhibits the reaction [APP protein alternative form results in decreased expression of BCL2 protein]
CTD PMID:10762662 PMID:19621015 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aprt adenine phosphoribosyl transferase increases expression EXP Lithium results in increased expression of APRT protein CTD PMID:18296634 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Aqp2 aquaporin 2 multiple interactions
decreases expression
increases expression
ISO
EXP
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]; PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of AQP2 protein]
Lithium results in increased expression of AQP2 protein
Lithium results in decreased expression of AQP2 mRNA; Lithium results in decreased expression of AQP2 protein
[Aldosterone co-treated with Lithium] affects the expression of AQP2 protein; [Spironolactone co-treated with Lithium] affects the expression of AQP2 protein; Hydrochlorothiazide inhibits the reaction [Lithium results in decreased expression of AQP2 protein]
CTD PMID:7535800 PMID:10966935 PMID:12472779 PMID:14613889 PMID:15153756 More... NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP Lithium results in decreased expression of AQP3 protein CTD PMID:10966935 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Aqp6 aquaporin 6 increases expression EXP Lithium results in increased expression of AQP6 mRNA; Lithium results in increased expression of AQP6 protein CTD PMID:11097619 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194
JBrowse link
G Arg2 arginase 2 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP [Lithium co-treated with Pilocarpine] results in decreased expression of ATF2 protein CTD PMID:19430551 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO Lithium results in decreased expression of ATM mRNA CTD PMID:19949822 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions
increases expression
decreases expression
ISO
EXP
Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 mRNA]; Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 protein]
Lithium results in increased expression of ATP1A1 protein
Lithium results in decreased expression of ATP1A1 mRNA
CTD PMID:15153756 PMID:18296634 PMID:19995221 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A2 mRNA] CTD PMID:19995221 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] CTD PMID:19149911 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP Lithium results in increased expression of ATP5F1B protein CTD PMID:18296634 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression EXP Lithium results in increased expression of ATP5F1D protein CTD PMID:18296634 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Avp arginine vasopressin multiple interactions
increases expression
affects expression
EXP Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein]
Lithium affects the expression of AVP protein
CTD PMID:2454589 PMID:3976404 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bag1 BAG cochaperone 1 increases expression EXP Lithium results in increased expression of BAG1 mRNA; Lithium results in increased expression of BAG1 protein CTD PMID:15872096 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
Lithium inhibits the reaction [Cadmium results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Morphine results in increased expression of BAX mRNA]
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX protein; Lithium inhibits the reaction [sodium arsenite affects the localization of BAX protein]; Lithium inhibits the reaction [sodium arsenite promotes the reaction [BAX protein binds to BAX protein]]
Lithium results in decreased expression of BAX mRNA
CTD PMID:17849503 PMID:18976035 PMID:19149911 PMID:19949822 PMID:20455018 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
EXP
ISO
Lithium inhibits the reaction [APP protein alternative form results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Cadmium results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Morphine results in decreased expression of BCL2 mRNA]
[Lithium Chloride results in increased abundance of Lithium] promotes the reaction [Paraquat results in increased expression of BCL2 mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 protein; [Paraquat co-treated with [Lithium Chloride results in increased abundance of Lithium]] results in increased expression of BCL2 protein; Lithium inhibits the reaction [Ethanol results in decreased expression of BCL2 mRNA]
Lithium results in increased expression of BCL2; Lithium results in increased expression of BCL2 mRNA; Lithium results in increased expression of BCL2 protein
CTD PMID:10762662 PMID:15581403 PMID:16288908 PMID:18976035 PMID:19149911 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor affects response to substance
multiple interactions
decreases expression
increases expression
increases response to substance
ISO
EXP
BDNF gene polymorphism affects the susceptibility to Lithium
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased expression of BDNF mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased secretion of BDNF protein]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BDNF mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased secretion of BDNF protein
Lithium results in decreased expression of BDNF mRNA
Lithium results in increased expression of BDNF mRNA; Lithium results in increased expression of BDNF protein
Diazepam inhibits the reaction [Lithium results in increased expression of BDNF mRNA]; Lithium inhibits the reaction [Dextroamphetamine results in decreased expression of BDNF protein]; Lithium inhibits the reaction [Ouabain results in decreased expression of BDNF protein]
BDNF protein results in increased susceptibility to Lithium
CTD PMID:9073163 PMID:16460767 PMID:17442489 PMID:19018715 PMID:19954800 More... NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Lithium results in increased expression of BIRC5 mRNA CTD PMID:16288908 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression EXP Lithium results in increased expression of BUB1B mRNA CTD PMID:21711903 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Calr calreticulin increases expression EXP Lithium results in increased expression of CALR mRNA; Lithium results in increased expression of CALR protein CTD PMID:16236328 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases expression EXP Lithium results in increased expression of CAMK4 mRNA; Lithium results in increased expression of CAMK4 protein CTD PMID:19711354 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression EXP Lithium results in increased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Lithium results in increased expression of CA2 protein CTD PMID:18296634 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp12 caspase 12 multiple interactions EXP [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein; Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein] CTD PMID:21429313 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
ISO
EXP
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Lithium inhibits the reaction [Monensin results in increased activity of CASP3 protein]; Lithium inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]
Lithium results in decreased activity of CASP3 protein
[Pilocarpine co-treated with Lithium] results in increased activity of CASP3 protein; Lithium inhibits the reaction [Cadmium results in increased expression of CASP3 protein]; Lithium inhibits the reaction [Colchicine results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]
CTD PMID:15005753 PMID:15581403 PMID:17849503 PMID:20149694 PMID:20455018 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA] CTD PMID:19149911 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Lithium inhibits the reaction [Monensin results in increased activity of CASP7 protein] CTD PMID:20799912 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Lithium inhibits the reaction [Camptothecin results in increased activity of CASP8 protein]; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein] CTD PMID:15475000 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase increases activity
multiple interactions
ISO
EXP
Lithium results in increased activity of CAT protein
Lithium inhibits the reaction [Ouabain results in decreased activity of CAT protein]
CTD PMID:18187119 PMID:20627318 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccna1 cyclin A1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] CTD PMID:19149911 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnb2 cyclin B2 increases expression EXP Lithium results in increased expression of CCNB2 mRNA CTD PMID:21711903 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA] CTD PMID:19149911 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Lithium inhibits the reaction [Ethanol results in decreased expression of CCND2 mRNA] CTD PMID:21878650 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression EXP Lithium results in decreased expression of CD151 mRNA CTD PMID:11682256 NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression EXP Lithium results in increased expression of CDCA3 mRNA CTD PMID:21711903 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdh1 cadherin 1 increases expression EXP Lithium results in increased expression of CDH1 protein CTD PMID:18296634 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein] CTD PMID:11337498 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression EXP Lithium results in decreased expression of CDKN1B mRNA; Lithium results in decreased expression of CDKN1B protein CTD PMID:15687245 PMID:18296634 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cfl1 cofilin 1 increases expression EXP Lithium results in increased expression of CFL1 protein CTD PMID:18296634 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Ckb creatine kinase B increases expression EXP Lithium results in increased expression of CKB protein CTD PMID:18296634 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression EXP Lithium results in increased expression of COX5A protein CTD PMID:18296634 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression EXP Lithium results in increased expression of COX5B protein CTD PMID:18296634 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
JBrowse link
G Crip1 cysteine rich protein 1 increases expression ISO Lithium results in increased expression of CRIP1 mRNA CTD PMID:21092101 NCBI chr 6:132,226,746...132,234,620
Ensembl chr 6:132,226,746...132,234,620
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP Lithium results in decreased expression of CRYAB protein CTD PMID:18296634 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
decreases expression
multiple interactions
affects localization
ISO
EXP
Lithium results in increased expression of CTNNB1 protein
Lithium results in decreased expression of CTNNB1 mRNA
Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA]; Lithium results in increased expression of and affects the localization of CTNNB1 protein
Lithium affects the localization of CTNNB1 protein
CTD PMID:12942141 PMID:16288908 PMID:18296634 PMID:19149911 PMID:19621015 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D increases expression EXP Lithium results in increased expression of CTSD protein CTD PMID:18296634 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression ISO Lithium results in decreased expression of DDR2 mRNA CTD PMID:21092101 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Ddx21 DExD-box helicase 21 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] CTD PMID:19149911 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Drd1 dopamine receptor D1 affects response to substance
increases response to substance
ISO DRD1 gene polymorphism affects the susceptibility to Lithium
DRD1 protein results in increased susceptibility to Lithium
CTD PMID:19153942 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP Lithium results in decreased expression of DRD2 protein CTD PMID:16478526 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Lithium results in increased expression of DUSP1 mRNA CTD PMID:21092101 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dynlrb1 dynein light chain roadblock-type 1 increases expression EXP Lithium results in increased expression of DYNLRB1 protein CTD PMID:18296634 NCBI chr 3:143,742,427...143,764,227
Ensembl chr 3:143,742,586...143,764,227
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Lithium results in increased expression of ECH1 protein CTD PMID:18296634 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ect2 epithelial cell transforming 2 increases expression EXP Lithium results in increased expression of ECT2 mRNA CTD PMID:21711903 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression EXP Lithium results in increased expression of EEF1A1 protein CTD PMID:18296634 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Eif3k eukaryotic translation initiation factor 3, subunit K increases expression EXP Lithium results in increased expression of EIF3K protein CTD PMID:18296634 NCBI chr 1:84,260,125...84,270,051
Ensembl chr 1:84,259,673...84,270,302
JBrowse link
G Etfb electron transfer flavoprotein subunit beta increases expression EXP Lithium results in increased expression of ETFB protein CTD PMID:18296634 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Ezr ezrin increases expression EXP Lithium results in increased expression of EZR mRNA; Lithium results in increased expression of EZR protein CTD PMID:15687245 PMID:18296634 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Lithium inhibits the reaction [Camptothecin results in increased expression of and affects the localization of FAS protein]; Lithium inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein] CTD PMID:15475000 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Lithium results in increased expression of FOS mRNA
Lithium results in increased expression of FOS protein
[Pilocarpine co-treated with Lithium] results in increased expression of FOS protein; Lithium promotes the reaction [Pilocarpine results in increased expression of FOS mRNA]
CTD PMID:7984056 PMID:8511714 PMID:9630518 PMID:11739594 PMID:17962567 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Lithium results in increased expression of FOSB mRNA CTD PMID:21092101 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Lithium inhibits the reaction [Cadmium results in decreased expression of FSHB protein] CTD PMID:20455018 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP Lithium results in increased expression of FTL protein CTD PMID:18296634 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA] CTD PMID:19149911 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Galm galactose mutarotase decreases expression EXP Lithium results in decreased expression of GALM protein CTD PMID:18296634 NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310
JBrowse link
G Ganab glucosidase II alpha subunit increases expression EXP Lithium results in increased expression of GANAB protein CTD PMID:18296634 NCBI chr 1:205,793,810...205,813,701
Ensembl chr 1:205,793,895...205,813,695
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased expression of GDNF protein CTD PMID:12914250 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Lithium results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gls glutaminase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA] CTD PMID:19149911 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 multiple interactions
decreases expression
EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA]
Lithium results in decreased expression of GOT2 protein
CTD PMID:18296634 PMID:19149911 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases activity EXP Lithium results in increased activity of GPD1 protein CTD PMID:3224025 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA] CTD PMID:19149911 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Lithium results in decreased expression of GRIA1 protein CTD PMID:18171924 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions
decreases expression
EXP [Lithium co-treated with Pilocarpine] results in increased expression of GRIA2 mRNA
Lithium results in decreased expression of GRIA2 protein
CTD PMID:16819974 PMID:18171924 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions EXP [Lithium co-treated with Pilocarpine] results in decreased expression of GRIA3 mRNA CTD PMID:16819974 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 decreases expression
multiple interactions
ISO
EXP
Lithium results in decreased expression of GRIK2 mRNA; Lithium results in decreased expression of GRIK2 protein
[Lithium co-treated with Pilocarpine] results in increased expression of GRIK2 mRNA
CTD PMID:16819974 PMID:19596362 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions EXP [Lithium co-treated with Pilocarpine] results in decreased expression of GRIK5 mRNA CTD PMID:16819974 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased phosphorylation of GRIN2A protein CTD PMID:16600505 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased phosphorylation of GRIN2B protein CTD PMID:16600505 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions
EXP
ISO
Lithium results in increased expression of GSK3A protein
Lithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3A protein]
CTD PMID:17849503 PMID:18296634 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity
multiple interactions
decreases phosphorylation
increases expression
increases phosphorylation
ISO
EXP
Lithium results in decreased activity of GSK3B protein
Lithium inhibits the reaction [GSK3B protein binds to TP53 protein]; Lithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3B protein]; Magnesium affects the reaction [Lithium results in decreased activity of GSK3B protein]
Lithium results in decreased phosphorylation of GSK3B protein
Lithium results in increased expression of GSK3B mRNA; Lithium results in increased expression of GSK3B protein
Lithium results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium results in increased phosphorylation of GSK3B protein
[Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein; [Lithium results in decreased activity of GSK3B protein] which results in increased activity of NFE2L2 protein; Lithium results in increased phosphorylation of and results in decreased activity of GSK3B protein
CTD PMID:10998351 PMID:15475000 PMID:15950778 PMID:16288908 PMID:17849503 More... NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of GSTA3 mRNA] CTD PMID:19149911 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Lithium results in increased expression of GSTA4 mRNA CTD PMID:18082333 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Lithium results in increased expression of GSTM1 mRNA; Lithium results in increased expression of GSTM1 protein CTD PMID:18082333 PMID:18296634 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression EXP Lithium results in increased expression of GSTM3 mRNA CTD PMID:18082333 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstm6 glutathione S-transferase, mu 6 increases expression EXP Lithium results in increased expression of GSTM5 mRNA CTD PMID:18082333 NCBI chr 2:195,579,566...195,584,340
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Lithium results in increased expression of GSTP1 protein CTD PMID:18296634 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hhex hematopoietically expressed homeobox multiple interactions
affects expression
ISO Folic Acid inhibits the reaction [Lithium affects the expression of HHEX mRNA]; Inositol promotes the reaction [Folic Acid inhibits the reaction [Lithium affects the expression of HHEX mRNA]] CTD PMID:19638421 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Lithium results in decreased expression of HILPDA mRNA CTD PMID:21092101 NCBI chr 4:57,871,076...57,875,206
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Lithium results in increased expression of HMOX1 protein
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of HMOX1 mRNA
CTD PMID:18619545 PMID:26074776 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Homer3 homer scaffold protein 3 decreases expression ISO Lithium results in decreased expression of HOMER3 mRNA CTD PMID:19949822 NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP Lithium results in increased expression of HPRT1 protein CTD PMID:18296634 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases expression EXP Lithium results in increased expression of HSD11B2 mRNA; Lithium results in increased expression of HSD11B2 protein CTD PMID:15687245 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 increases expression EXP Lithium results in increased expression of HSD17B10 protein CTD PMID:18296634 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression EXP Lithium results in increased expression of HSP90B1 mRNA; Lithium results in increased expression of HSP90B1 protein CTD PMID:16236328 PMID:18296634 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP Lithium results in increased expression of HSPA1B protein CTD PMID:18296634 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases expression EXP Lithium results in decreased expression of HSPA1L protein CTD PMID:18296634 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP [Pilocarpine co-treated with Lithium] results in increased expression of HSPA5 mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of HSPA5 protein; Edaravone promotes the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of HSPA5 protein]
Lithium results in increased expression of HSPA5 mRNA; Lithium results in increased expression of HSPA5 protein
CTD PMID:16236328 PMID:18296634 PMID:21429313 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of HSPA9 mRNA]
Lithium results in increased expression of HSPA9 protein
CTD PMID:18296634 PMID:19149911 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein] CTD PMID:31760073 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
ISO Lithium results in increased expression of IL10 mRNA
Lithium inhibits the reaction [Olanzapine results in decreased expression of IL10 protein]
CTD PMID:30695037 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Lithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:19159680 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression
ISO [Pilocarpine co-treated with Lithium] results in increased expression of IL1B mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of IL1B protein; Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of IL1B mRNA]; Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of IL1B protein]
Lithium inhibits the reaction [Olanzapine results in increased expression of IL1B mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL1B protein]
Lithium results in decreased expression of IL1B mRNA
Lithium results in increased expression of IL1B protein
CTD PMID:19951488 PMID:30695037 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO Lithium results in increased expression of IL2 protein CTD PMID:10880530 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Cadmium results in decreased expression of IL4 protein]
Lithium results in increased expression of IL4 protein
CTD PMID:20455018 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Lithium inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL6 mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL6 protein]
Lithium results in increased expression of IL6 mRNA
CTD PMID:19159680 PMID:30695037 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impa1 inositol monophosphatase 1 decreases response to substance ISO IMPA1 protein results in decreased susceptibility to Lithium CTD PMID:17460611 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased expression of JUN protein; Lithium promotes the reaction [Pilocarpine results in increased expression of JUN mRNA] CTD PMID:7984056 PMID:19430551 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Lithium promotes the reaction [Pilocarpine results in increased expression of JUNB mRNA] CTD PMID:7984056 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kif20a kinesin family member 20A increases expression EXP Lithium results in increased expression of KIF20A mRNA CTD PMID:21711903 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif23 kinesin family member 23 increases expression EXP Lithium results in increased expression of KIF23 mRNA CTD PMID:21711903 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kifc1 kinesin family member C1 increases expression EXP Lithium results in increased expression of KIFC1 mRNA CTD PMID:21711903 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Klf6 Kruppel-like factor 6 affects expression ISO Lithium affects the expression of KLF6 mRNA CTD PMID:21092101 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Lithium inhibits the reaction [Cadmium results in decreased expression of LHB protein] CTD PMID:20455018 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,898,267...95,901,963
Ensembl chr 1:95,898,267...95,901,963
JBrowse link
G Lmna lamin A/C increases expression EXP Lithium results in increased expression of LMNA protein CTD PMID:18296634 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO [Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein] which results in increased phosphorylation of MAP2K1 protein CTD PMID:19159680 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases degradation
multiple interactions
ISO Lithium results in increased degradation of MAP3K8 protein alternative form
[Lithium results in increased degradation of NFKB1 protein] inhibits the reaction [NFKB1 protein binds to MAP3K8 protein]; [Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein] which results in increased phosphorylation of MAP2K1 protein; Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP3K8 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAP3K8 protein
CTD PMID:19159680 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
increases phosphorylation
increases expression
multiple interactions
ISO
EXP
Lithium results in increased activity of MAPK1 protein
Lithium results in increased phosphorylation of MAPK1 protein
Lithium results in increased expression of MAPK1 protein
Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD PMID:11756416 PMID:18296634 PMID:19159680 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
multiple interactions
ISO Lithium results in increased activity of MAPK3 protein
Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Lithium results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD PMID:11756416 PMID:19159680 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression
increases phosphorylation
EXP Lithium results in increased expression of MAPK8 protein
Lithium results in increased phosphorylation of MAPK8 protein
CTD PMID:18296634 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression EXP Lithium results in increased expression of MAPK9 protein CTD PMID:18296634 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO Lithium inhibits the reaction [Acrolein results in increased phosphorylation of MAPT protein] CTD PMID:12605413 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Mir34a microRNA 34a multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of MIR34A mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of MIR34A mRNA CTD PMID:26074776 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir497 microRNA 497 multiple interactions ISO Lithium inhibits the reaction [Ethanol results in increased expression of MIR497] CTD PMID:21878650 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP Lithium results in increased expression of MKI67 mRNA CTD PMID:21711903 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL18 mRNA] CTD PMID:19149911 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL53 mRNA] CTD PMID:19149911 NCBI chr 4:115,615,329...115,616,219 JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein CTD PMID:17921520 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myl6 myosin light chain 6 decreases expression EXP Lithium results in decreased expression of MYL6 protein CTD PMID:18296634 NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases activity
ISO [Lithium results in decreased activity of GSK3B protein] which results in increased activity of NFE2L2 protein
[Lithium Chloride results in increased abundance of Lithium] which affects the localization of NFE2L2 protein; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NFE2L2 mRNA
Lithium results in increased activity of NFE2L2 protein
CTD PMID:18619545 PMID:26074776 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases degradation
ISO [Lithium results in increased degradation of NFKB1 protein] inhibits the reaction [NFKB1 protein binds to MAP3K8 protein]; Lithium inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased localization of NFKB1 protein] CTD PMID:19159680 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Lithium results in increased expression of NME2 protein CTD PMID:18296634 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression
multiple interactions
EXP Lithium results in increased expression of NOS1 mRNA
[Pilocarpine co-treated with Lithium] results in increased expression of NOS1 protein; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of NOS1 protein]
CTD PMID:11087959 PMID:20149694 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Pilocarpine co-treated with Lithium] results in increased expression of NOS2 protein; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of NOS2 protein] CTD PMID:20149694 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npy neuropeptide Y increases expression EXP Lithium results in increased expression of NPY mRNA; Lithium results in increased expression of NPY protein CTD PMID:17572454 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NQO1 mRNA CTD PMID:26074776 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 affects response to substance ISO NR1D1 gene polymorphism affects the susceptibility to Lithium CTD PMID:20348464 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Lithium inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]]; Lithium inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]
Lithium inhibits the reaction [Dexamethasone affects the localization of and results in increased activity of NR3C1 protein]
CTD PMID:15249158 PMID:15872096 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Lithium results in increased expression of NR4A2 mRNA CTD PMID:21092101 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nsfl1c NSFL1 cofactor increases expression EXP Lithium results in increased expression of NSFL1C protein CTD PMID:18296634 NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870
JBrowse link
G Ntf3 neurotrophin 3 multiple interactions
increases expression
EXP Lithium inhibits the reaction [Amphetamine affects the expression of NTF3 protein]
Lithium results in increased expression of NTF3 protein
CTD PMID:17512948 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Nudt4 nudix hydrolase 4 increases expression EXP Lithium results in increased expression of NUDT4 mRNA CTD PMID:11331144 NCBI chr 7:30,188,100...30,204,620
Ensembl chr 7:30,188,100...30,204,615
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Lithium results in decreased expression of OGG1 mRNA CTD PMID:22641096 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide increases expression
increases secretion
EXP Lithium results in increased expression of OXT mRNA
Lithium results in increased secretion of OXT protein
CTD PMID:11739594 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 increases expression EXP Lithium results in increased expression of P2RY4 mRNA CTD PMID:19244398 NCBI chr  X:65,681,680...65,717,404
Ensembl chr  X:65,683,232...65,721,748
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Lithium inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:17849503 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 increases expression ISO Lithium results in increased expression of PARP4 mRNA CTD PMID:19949822 NCBI chr15:30,690,503...30,792,868
Ensembl chr15:30,686,613...30,828,810
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 increases expression ISO Lithium results in increased expression of PCMT1 mRNA CTD PMID:19949822 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pdcd6 programmed cell death 6 increases expression EXP Lithium results in increased expression of PDCD6 protein CTD PMID:18296634 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Lithium results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:19,706,649...19,751,937
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP Lithium results in decreased expression of PDE4B protein CTD PMID:20222156 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde8b phosphodiesterase 8B decreases expression EXP Lithium results in decreased expression of PDE8B mRNA CTD PMID:20222156 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression EXP Lithium results in increased expression of PDIA3 protein CTD PMID:18296634 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP Lithium results in increased expression of PEBP1 protein CTD PMID:18296634 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 increases expression ISO Lithium results in increased expression of PEX1 mRNA CTD PMID:19949822 NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression EXP Lithium results in increased expression of PGAM1 protein CTD PMID:18296634 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Phb1 prohibitin 1 increases expression EXP Lithium results in increased expression of PHB1 protein CTD PMID:18296634 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression ISO Lithium results in increased expression of PLA2G4A mRNA; Lithium results in increased expression of PLA2G4A protein CTD PMID:17594078 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pls3 plastin 3 increases expression EXP Lithium results in increased expression of PLS3 protein CTD PMID:18296634 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO [Guanosine Triphosphate co-treated with Lithium] results in decreased activity of POMC protein modified form CTD PMID:2550106 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP Lithium results in increased expression of PPIA protein CTD PMID:18296634 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression EXP Lithium results in increased expression of PRDX5 protein CTD PMID:18296634 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
decreases response to substance
increases response to substance
ISO PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of AQP2 protein]; PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of SLC14A2 protein]
PRKCA gene mutant form results in decreased susceptibility to Lithium
PRKCA gene results in increased susceptibility to Lithium
CTD PMID:25006961 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in increased expression of PRKCE mRNA] CTD PMID:19149911 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO Lithium inhibits the reaction [PRKCG protein mutant form binds to PRKCG protein mutant form] CTD PMID:20398063 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prl prolactin multiple interactions EXP Lithium inhibits the reaction [Cadmium results in increased expression of PRL protein] CTD PMID:20455018 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP Lithium results in increased expression of PSMB1 protein CTD PMID:18296634 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP Lithium results in increased expression of PSMB9 protein CTD PMID:18296634 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 decreases expression ISO Lithium results in decreased expression of PSMD1 mRNA CTD PMID:19949822 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 increases expression EXP Lithium results in increased expression of PSMD13 protein CTD PMID:18296634 NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 increases expression EXP Lithium results in increased expression of PSMD8 protein CTD PMID:18296634 NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
JBrowse link
G Psme2 proteasome activator subunit 2 increases expression EXP Lithium results in increased expression of PSME2 protein CTD PMID:18296634 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
JBrowse link
G Pth parathyroid hormone increases expression EXP
ISO
Lithium results in increased expression of PTH protein CTD PMID:581022 PMID:7212107 PMID:8840263 PMID:10423626 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased activity of PTK2B protein CTD PMID:16600505 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of QARS1 mRNA] CTD PMID:19149911 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression EXP Lithium results in increased expression of RACGAP1 mRNA CTD PMID:21711903 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase decreases expression ISO Lithium results in decreased expression of RAD18 mRNA CTD PMID:22641096 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP Lithium results in increased expression of RAN protein CTD PMID:18296634 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Lithium promotes the reaction [Lipopolysaccharides results in increased localization of REL protein] CTD PMID:19159680 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity
ISO Lithium inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased localization of RELA protein]
Lithium results in increased activity of RELA protein
CTD PMID:11756416 PMID:19159680 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Reln reelin decreases expression EXP Lithium results in decreased expression of RELN mRNA; Lithium results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Ret ret proto-oncogene multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased expression of RET protein CTD PMID:12914250 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO Lithium results in increased expression of RGCC mRNA CTD PMID:21092101 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Lithium results in increased expression of RGS2 mRNA CTD PMID:21092101 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase increases expression ISO Lithium results in increased expression of RNMT mRNA CTD PMID:19949822 NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775
JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression EXP Lithium results in decreased expression of S100A4 protein CTD PMID:18296634 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100a6 S100 calcium binding protein A6 decreases expression EXP Lithium results in decreased expression of S100A6 protein CTD PMID:18296634 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions ISO [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Lithium CTD PMID:18665318 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions ISO [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Lithium CTD PMID:18665318 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions
affects expression
ISO
EXP
[SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] which results in increased transport of Lithium
Lithium affects the expression of SCNN1G protein
CTD PMID:12928314 PMID:18665318 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression EXP Lithium results in increased expression of SLC12A1 mRNA; Lithium results in increased expression of SLC12A1 protein CTD PMID:10966935 PMID:12472779 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc13a2 solute carrier family 13 member 2 multiple interactions ISO
EXP
Lithium promotes the reaction [SLC13A2 protein results in increased uptake of Citric Acid]
Lithium inhibits the reaction [SLC13A2 protein results in increased uptake of Citric Acid]
CTD PMID:12826022 NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
JBrowse link
G Slc14a2 solute carrier family 14 member 2 decreases expression
multiple interactions
ISO Lithium results in decreased expression of SLC14A2 protein
PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of SLC14A2 protein]
CTD PMID:25006961 NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Lithium results in increased expression of SLC17A6 mRNA; Lithium results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression ISO Lithium results in increased expression of SLC17A7 mRNA; Lithium results in increased expression of SLC17A7 protein CTD PMID:16111724 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions ISO Lithium promotes the reaction [SLC20A1 protein results in increased uptake of Phosphates] CTD PMID:17494632 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
JBrowse link
G Slc20a2 solute carrier family 20 member 2 multiple interactions ISO Lithium promotes the reaction [SLC20A2 protein results in increased uptake of Phosphates] CTD PMID:17494632 NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions
decreases expression
increases activity
ISO Phloretin inhibits the reaction [SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]]; SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]
Lithium results in decreased expression of SLC9A1 mRNA
Lithium results in increased activity of SLC9A1 protein
CTD PMID:12765964 PMID:18506424 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Slc9a3 solute carrier family 9 member A3 increases expression EXP Lithium results in increased expression of SLC9A3 protein CTD PMID:10966935 NCBI chr 1:29,124,633...29,167,912
Ensembl chr 1:29,124,674...29,167,417
JBrowse link
G Slc9b2 solute carrier family 9 member B2 multiple interactions ISO SLC9B2 protein affects the transport of [Sodium co-treated with Lithium] CTD PMID:18000046 NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP Lithium results in decreased expression of SLCO1A4 mRNA CTD PMID:19570321 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slit2 slit guidance ligand 2 increases expression
decreases expression
EXP Lithium results in increased expression of SLIT2 protein
Lithium results in decreased expression of SLIT2 protein
CTD PMID:20153733 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
G Snca synuclein alpha multiple interactions EXP Lithium inhibits the reaction [Rotenone results in increased expression of and results in increased phosphorylation of SNCA protein] CTD PMID:25433145 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
EXP Lithium results in increased expression of SOD1 protein
Lithium inhibits the reaction [Cadmium results in decreased expression of SOD1 protein]
CTD PMID:18296634 PMID:20455018 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in decreased activity of SOD2 protein] CTD PMID:31760073 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sparcl1 SPARC like 1 affects localization EXP Lithium affects the localization of SPARCL1 protein CTD PMID:18488994 NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex increases expression EXP Lithium results in increased expression of SPC25 mRNA CTD PMID:21711903 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP [Lithium co-treated with Pilocarpine] results in increased activity of SRC protein CTD PMID:16600505 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 increases expression EXP Lithium results in increased expression of SRCIN1 protein CTD PMID:18296634 NCBI chr10:82,511,101...82,568,706
Ensembl chr10:82,504,393...82,571,040
JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO Lithium results in decreased expression of STC2 mRNA CTD PMID:21092101 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression EXP Lithium results in increased expression of STIP1 protein CTD PMID:18296634 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression ISO Lithium results in decreased expression of SULT1A1 mRNA CTD PMID:19949822 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP [Pilocarpine co-treated with Lithium] results in increased expression of TAC1 mRNA; [Pilocarpine co-treated with Lithium] results in increased expression of TAC1 protein modified form; Dizocilpine Maleate inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of TAC1 protein modified form] CTD PMID:11074153 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19149911 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP Lithium results in decreased expression of TJP1 protein CTD PMID:17533168 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tkt transketolase increases expression EXP Lithium results in increased expression of TKT protein CTD PMID:18296634 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tmx4 thioredoxin-related transmembrane protein 4 increases expression EXP Lithium results in increased expression of TMX4 protein CTD PMID:18296634 NCBI chr 3:121,856,237...121,899,680
Ensembl chr 3:121,856,261...121,899,641
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
EXP
ISO
Lithium inhibits the reaction [Cadmium results in increased expression of TNF protein]
Lithium inhibits the reaction [Olanzapine results in increased expression of TNF mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of TNF protein]
Lithium results in decreased expression of TNF mRNA
CTD PMID:20455018 PMID:30695037 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP Lithium results in increased expression of TOP2A mRNA CTD PMID:21711903 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Lithium inhibits the reaction [GSK3B protein binds to TP53 protein]; Lithium inhibits the reaction [sodium arsenite results in increased expression of and affects the localization of TP53 protein]
TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein]
CTD PMID:11337498 PMID:15475000 PMID:17849503 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Lithium results in increased expression of TPI1 protein CTD PMID:18296634 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tpm1 tropomyosin 1 decreases expression EXP Lithium results in decreased expression of TPM1 protein CTD PMID:18296634 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases transport ISO TRPC6 protein results in increased transport of Lithium CTD PMID:11179201 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO Lithium inhibits the reaction [Monensin results in increased expression of TRPM2 protein alternative form] CTD PMID:20799912 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ttk Ttk protein kinase increases expression EXP Lithium results in increased expression of TTK mRNA CTD PMID:21711903 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression EXP Lithium results in increased expression of UBE2C mRNA CTD PMID:21711903 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Uck1 uridine-cytidine kinase 1 increases expression EXP Lithium results in increased expression of UCK1 protein CTD PMID:18296634 NCBI chr 3:15,538,580...15,544,465
Ensembl chr 3:15,538,591...15,544,465
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of UGCG mRNA CTD PMID:26074776 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 increases expression EXP Lithium results in increased expression of UHRF1 mRNA CTD PMID:21711903 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 increases expression EXP Lithium results in increased expression of UQCRFS1 protein CTD PMID:18296634 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
ISO
EXP
Lithium results in decreased expression of VEGFA mRNA
Lithium results in increased expression of VEGFA mRNA; Lithium results in increased expression of VEGFA protein
CTD PMID:16288908 PMID:17533168 PMID:19949822 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vps29 VPS29 retromer complex component increases expression EXP Lithium results in increased expression of VPS29 protein CTD PMID:18296634 NCBI chr12:34,208,911...34,217,977
Ensembl chr12:34,207,263...34,217,964
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon increases expression EXP Lithium results in increased expression of YWHAE protein CTD PMID:18296634 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta decreases expression EXP Lithium results in decreased expression of YWHAQ protein CTD PMID:18296634 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link
lithium carbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
EXP Lithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of ALAD protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of ALAD protein]; Zinc Sulfate inhibits the reaction [Lithium Carbonate results in decreased activity of ALAD protein] CTD PMID:19083387 PMID:28988373 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP Lithium Carbonate results in increased activity of CASP3 protein
Butylated Hydroxytoluene inhibits the reaction [Lithium Carbonate results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Lithium Carbonate results in increased activity of CASP3 protein]
CTD PMID:27588890 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Lithium Carbonate results in decreased activity of CAT protein
Lithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of CAT protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of CAT protein]
CTD PMID:28988373 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP Lithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of GSR protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of GSR protein] CTD PMID:28988373 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA CTD PMID:29594315 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Lithium Carbonate results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases activity
multiple interactions
EXP Lithium Carbonate results in decreased activity of PFKFB2 protein
Lithium Carbonate inhibits the reaction [Streptozocin results in decreased activity of PFKFB2 protein]
CTD PMID:10700396 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression ISO Lithium Carbonate results in increased expression of PLA2G4A mRNA; Lithium Carbonate results in increased expression of PLA2G4A protein CTD PMID:17594078 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pth parathyroid hormone increases expression ISO Lithium Carbonate results in increased expression of PTH protein CTD PMID:3083797 PMID:18234408 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
lithium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2ml1 alpha-2-macroglobulin-like 1 decreases expression ISO Lithium Chloride results in decreased expression of OVOS2 mRNA CTD PMID:23527032 NCBI chr 4:161,815,111...161,857,286
Ensembl chr 4:161,814,708...161,857,343
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression ISO Lithium Chloride results in decreased expression of ABAT mRNA CTD PMID:15711924 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Lithium Chloride results in increased expression of ABCB1 protein CTD PMID:18624906 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abhd11 abhydrolase domain containing 11 increases expression ISO Lithium Chloride results in increased expression of ABHD11 mRNA CTD PMID:23527032 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398
JBrowse link
G Abi2 abl-interactor 2 decreases expression ISO Lithium Chloride results in decreased expression of ABI2 mRNA CTD PMID:23527032 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Lithium Chloride results in decreased expression of ACADM mRNA; Lithium Chloride results in decreased expression of ACADM protein CTD PMID:26993217 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of ACE protein] CTD PMID:32494933 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases stability
increases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein CTD PMID:22944069 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Adgrb3 adhesion G protein-coupled receptor B3 increases expression ISO Lithium Chloride results in increased expression of ADGRB3 mRNA CTD PMID:15711924 NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 increases expression ISO Lithium Chloride results in increased expression of ADGRE5 mRNA CTD PMID:23527032 NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] CTD PMID:32494933 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP [Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of AGTR2 mRNA CTD PMID:32494933 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA CTD PMID:21498875 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein]
[Lithium Chloride co-treated with Pilocarpine] results in increased phosphorylation of AKT1 protein
CTD PMID:22820424 PMID:31018114 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression ISO Lithium Chloride results in decreased expression of ALDH1A3 mRNA CTD PMID:15711924 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO Lithium Chloride results in increased expression of ALOX5AP mRNA CTD PMID:23527032 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO Lithium Chloride results in increased expression of ALPG mRNA CTD PMID:23527032 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836
JBrowse link
G Alpp alkaline phosphatase, placental increases activity ISO Lithium Chloride results in increased activity of ALPP protein CTD PMID:16053526 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Amy2a3 amylase 2a3 multiple interactions EXP Atenolol inhibits the reaction [Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein]; Granisetron inhibits the reaction [Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein]; Lithium Chloride results in increased secretion of and results in increased activity of AMY1A protein CTD PMID:21173550 NCBI chr 2:201,317,916...201,326,487
Ensembl chr 2:201,317,920...201,326,532
JBrowse link
G Anxa11 annexin A11 increases expression ISO Lithium Chloride results in increased expression of ANXA11 mRNA CTD PMID:23527032 NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 decreases expression ISO Lithium Chloride results in decreased expression of APC2 mRNA CTD PMID:23527032 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase increases expression ISO Lithium Chloride results in increased expression of APEH mRNA CTD PMID:23527032 NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Lithium Chloride inhibits the reaction [Copper affects the localization of APP protein] CTD PMID:24610780 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp2 aquaporin 2 decreases expression
multiple interactions
ISO
EXP
Lithium Chloride results in decreased expression of AQP2 mRNA; Lithium Chloride results in decreased expression of AQP2 protein
PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]
CTD PMID:18653713 PMID:19692487 PMID:21734099 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Arf6 ADP-ribosylation factor 6 increases expression ISO Lithium Chloride results in increased expression of ARF6 mRNA CTD PMID:15711924 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 increases expression ISO Lithium Chloride results in increased expression of ARHGAP29 mRNA CTD PMID:15711924 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 decreases expression ISO Lithium Chloride results in decreased expression of ASB1 mRNA CTD PMID:23527032 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Lithium Chloride results in increased expression of ATF4 mRNA CTD PMID:15711924 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp5me ATP synthase membrane subunit e decreases expression ISO Lithium Chloride results in decreased expression of ATP5ME mRNA CTD PMID:15711924 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Avp arginine vasopressin increases expression EXP Lithium Chloride results in increased expression of AVP mRNA; Lithium Chloride results in increased expression of AVP protein CTD PMID:9406968 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Axin2 axin 2 multiple interactions
increases expression
ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; Phenobarbital inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
CTD PMID:20694829 PMID:21498875 PMID:22493441 PMID:23326414 PMID:24534281 More... NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO Lithium Chloride results in increased expression of B4GALT1 mRNA CTD PMID:23527032 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Lithium Chloride inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein]
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of BAX protein]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of BAX protein
CTD PMID:26074776 PMID:30171970 PMID:31220555 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Lithium Chloride results in increased expression of BCL2 mRNA; Lithium Chloride results in increased expression of BCL2 protein
[Lithium Chloride results in increased abundance of Lithium] promotes the reaction [Paraquat results in increased expression of BCL2 mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BCL2 protein; [Paraquat co-treated with [Lithium Chloride results in increased abundance of Lithium]] results in increased expression of BCL2 protein
Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
Lithium Chloride inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
CTD PMID:17404573 PMID:18830594 PMID:19101580 PMID:19408126 PMID:26074776 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Lithium Chloride results in increased expression of BCL2L1 mRNA; Lithium Chloride results in increased expression of BCL2L1 protein CTD PMID:19101580 PMID:22493441 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Lithium Chloride results in increased expression of BCL3 mRNA CTD PMID:23527032 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased expression of BDNF mRNA]; [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in decreased secretion of BDNF protein]; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of BDNF mRNA; [Lithium Chloride results in increased abundance of Lithium] which results in increased secretion of BDNF protein CTD PMID:26074776 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions
affects expression
ISO Lithium Chloride affects the reaction [perfluorooctane sulfonic acid affects the expression of BGLAP mRNA]
Lithium Chloride affects the expression of BGLAP mRNA
CTD PMID:30738844 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions EXP
ISO
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA]
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]
CTD PMID:24464479 PMID:28886972 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO Lithium Chloride results in increased expression of BMP4 mRNA CTD PMID:15711924 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Lithium Chloride results in increased expression of BST2 mRNA CTD PMID:23527032 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Calr calreticulin decreases expression ISO Lithium Chloride results in decreased expression of CALR mRNA CTD PMID:26993217 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases activity
ISO
EXP
[Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [fipronil results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CASP3 mRNA]]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
Lithium Chloride results in decreased activity of CASP3 protein
CTD PMID:19101580 PMID:21296133 PMID:21364661 PMID:24464479 PMID:26074776 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO Lithium Chloride results in increased expression of CASP4 mRNA CTD PMID:23527032 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form] CTD PMID:28886972 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Lithium Chloride inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein] CTD PMID:28343033 PMID:28886972 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Lithium Chloride results in increased expression of CCL2 mRNA CTD PMID:33901603 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccna1 cyclin A1 increases expression
decreases expression
ISO Lithium Chloride results in increased expression of CCNA1 protein
Lithium Chloride results in decreased expression of CCNA1 mRNA
CTD PMID:19101580 PMID:23527032 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of CCNA2 mRNA; Lithium Chloride results in decreased expression of CCNA2 protein
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]
CTD PMID:15845746 PMID:17440966 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Lithium Chloride results in decreased expression of CCNB2 mRNA CTD PMID:15711924 PMID:17440966 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 affects localization
decreases expression
increases expression
multiple interactions
decreases phosphorylation
ISO Lithium Chloride affects the localization of CCND1 protein
Lithium Chloride results in decreased expression of CCND1 protein
Lithium Chloride results in increased expression of CCND1 mRNA; Lithium Chloride results in increased expression of CCND1 protein
Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol affects the localization of CCND1 protein]]
Lithium Chloride results in decreased phosphorylation of CCND1 protein
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [baicalein results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [kahweol results in increased phosphorylation of CCND1 protein]; Lithium Chloride inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of CCND1 mRNA]
CTD PMID:15753396 PMID:15845746 PMID:16024653 PMID:16076840 PMID:17440966 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Lithium Chloride results in increased expression of CCND2 mRNA CTD PMID:27226553 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Lithium Chloride results in increased expression of CCND3 mRNA CTD PMID:27226553 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne2 cyclin E2 decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CCNE2 mRNA; Lithium Chloride results in decreased expression of CCNE2 protein
Lithium Chloride results in increased expression of CCNE2 mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CCNG2 mRNA
Lithium Chloride results in increased expression of CCNG2 mRNA
CTD PMID:15711924 PMID:17440966 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cd40 CD40 molecule increases expression
multiple interactions
EXP Lithium Chloride results in increased expression of CD40 protein
rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of CD40 protein]
CTD PMID:18455351 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO Lithium Chloride results in increased expression of CD44 mRNA CTD PMID:23527032 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc25c cell division cycle 25C decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CDC25C mRNA; Lithium Chloride results in decreased expression of CDC25C protein
Lithium Chloride results in increased expression of CDC25C mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 decreases expression ISO Lithium Chloride results in decreased expression of CDC42EP2 mRNA CTD PMID:23527032 NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Lithium Chloride results in increased expression of CDC42SE1 mRNA CTD PMID:23527032 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
JBrowse link
G Cdc6 cell division cycle 6 decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of CDC6 mRNA; Lithium Chloride results in decreased expression of CDC6 protein
Lithium Chloride results in increased expression of CDC6 mRNA
CTD PMID:17440966 PMID:22493441 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdc7 cell division cycle 7 decreases expression ISO Lithium Chloride results in decreased expression of CDC7 mRNA CTD PMID:23527032 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO [Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDH1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in increased expression of CDH1 protein]
Lithium Chloride results in decreased expression of CDH1 protein
CTD PMID:20348013 PMID:22134133 PMID:32112862 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh11 cadherin 11 multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein] CTD PMID:19274078 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions
increases expression
ISO Lithium Chloride results in decreased expression of CDH2 mRNA
Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of CDH2 protein]
Lithium Chloride results in increased expression of CDH2 protein
CTD PMID:23527032 PMID:32112862 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Lithium Chloride results in increased expression of CDKN1A mRNA; Lithium Chloride results in increased expression of CDKN1A protein CTD PMID:17440966 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO Lithium Chloride results in decreased expression of CDKN1B mRNA CTD PMID:17440966 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Lithium Chloride results in increased expression of CDKN1C mRNA CTD PMID:17440966 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Lithium Chloride results in increased expression of CDKN2A mRNA CTD PMID:23527032 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO Lithium Chloride results in increased expression of CDKN2B mRNA CTD PMID:23527032 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of CEBPA mRNA] CTD PMID:32494933 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Lithium Chloride results in increased expression of CEBPD mRNA CTD PMID:23527032 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Celf2 CUGBP, Elav-like family member 2 decreases expression ISO Lithium Chloride results in decreased expression of CELF2 mRNA CTD PMID:23527032 NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
JBrowse link
G Cenpf centromere protein F decreases expression ISO Lithium Chloride results in decreased expression of CENPF mRNA CTD PMID:15711924 PMID:23527032 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cep250 centrosomal protein 250 decreases expression ISO Lithium Chloride results in decreased expression of CEP250 mRNA CTD PMID:23527032 NCBI chr 3:144,470,946...144,516,125
Ensembl chr 3:144,471,214...144,516,125
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist increases expression ISO Lithium Chloride results in increased expression of CER1 mRNA CTD PMID:26272751 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Cfd complement factor D increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of CFD mRNA
Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of CFD mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of CFD mRNA]
CTD PMID:23527032 PMID:28291828 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cftr CF transmembrane conductance regulator increases expression ISO Lithium Chloride results in increased expression of CFTR mRNA CTD PMID:23527032 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chga chromogranin A decreases expression ISO Lithium Chloride results in decreased expression of CHGA mRNA; Lithium Chloride results in decreased expression of CHGA protein CTD PMID:33901603 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chgb chromogranin B decreases expression ISO Lithium Chloride results in decreased expression of CHGB mRNA CTD PMID:33901603 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO Lithium Chloride results in increased expression of CHORDC1 mRNA CTD PMID:15711924 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Ckm creatine kinase, M-type increases expression ISO Lithium Chloride results in increased expression of CKM mRNA CTD PMID:20694829 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Cldn1 claudin 1 increases expression ISO Lithium Chloride results in increased expression of CLDN1 mRNA CTD PMID:33901603 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn12 claudin 12 decreases expression ISO Lithium Chloride results in decreased expression of CLDN12 mRNA CTD PMID:33901603 NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
JBrowse link
G Cldn15 claudin 15 decreases expression ISO Lithium Chloride results in decreased expression of CLDN15 mRNA; Lithium Chloride results in decreased expression of CLDN15 protein CTD PMID:33901603 NCBI chr12:19,698,169...19,708,419
Ensembl chr12:19,698,337...19,706,819
JBrowse link
G Col13a1 collagen type XIII alpha 1 chain decreases expression ISO Lithium Chloride results in decreased expression of COL13A1 mRNA CTD PMID:23527032 NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032
JBrowse link
G Col1a2 collagen type I alpha 2 chain affects expression ISO Lithium Chloride affects the expression of COL1A2 mRNA CTD PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression
increases phosphorylation
EXP
ISO
Lithium Chloride results in increased expression of CREB1 mRNA
Lithium Chloride results in increased phosphorylation of CREB1 protein
CTD PMID:18830594 PMID:19285016 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crisp2 cysteine-rich secretory protein 2 decreases expression ISO Lithium Chloride results in decreased expression of CRISP2 mRNA CTD PMID:15711924 NCBI chr 9:20,107,649...20,131,967
Ensembl chr 9:20,107,701...20,131,959
JBrowse link
G Ctcf CCCTC-binding factor increases expression EXP Lithium Chloride results in increased expression of CTCF mRNA CTD PMID:19285016 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
affects localization
increases stability
increases activity
increases localization
decreases phosphorylation
ISO
EXP
[Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; Hexachlorophene inhibits the reaction [Lithium Chloride results in increased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Aspirin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [celastrol results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Indomethacin results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of and results in increased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Lithium Chloride results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased localization of CTNNB1 protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of CTNNB1 protein; Lithium Chloride results in increased localization of and results in increased activity of CTNNB1 protein; MALAT1 protein affects the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]
Lithium Chloride affects the localization of CTNNB1 protein; Lithium Chloride affects the localization of CTNNB1 protein modified form
Lithium Chloride results in increased stability of CTNNB1 protein
Lithium Chloride results in increased expression of CTNNB1 mRNA; Lithium Chloride results in increased expression of CTNNB1 protein
Lithium Chloride results in increased activity of CTNNB1 protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Lithium Chloride inhibits the reaction [wogonin results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein]
Lithium Chloride results in increased localization of CTNNB1 protein
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CTNNB1 protein]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride results in increased expression of and affects the localization of CTNNB1 protein
Lithium Chloride results in decreased phosphorylation of CTNNB1 protein
CTD PMID:12813129 PMID:15364539 PMID:16053526 PMID:16076840 PMID:16735606 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Lithium Chloride results in increased expression of CYP1A1 mRNA CTD PMID:21498875 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP Lithium Chloride promotes the reaction [Cadmium results in increased expression of DDIT3 protein] CTD PMID:27658547 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Diras3 DIRAS family GTPase 3 increases expression ISO Lithium Chloride results in increased expression of DIRAS3 mRNA CTD PMID:15711924 NCBI chr 6:130,524,972...130,527,690
Ensembl chr 6:130,524,742...130,530,825
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 multiple interactions ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of DVL2 protein] CTD PMID:30171970 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
JBrowse link
G Ebf1 EBF transcription factor 1 increases expression ISO Lithium Chloride results in increased expression of EBF1 mRNA CTD PMID:27226553 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
JBrowse link
G Efna3 ephrin A3 decreases expression EXP Lithium Chloride results in decreased expression of EFNA3 mRNA CTD PMID:18772502 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
ISO [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA]
Lithium Chloride results in increased expression of EGFR mRNA; Lithium Chloride results in increased expression of EGFR protein
CTD PMID:22493441 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 decreases expression ISO Lithium Chloride results in decreased expression of ENOX2 mRNA CTD PMID:23527032 NCBI chr  X:128,270,941...128,593,074
Ensembl chr  X:128,271,074...128,593,039
JBrowse link
G Epha5 EPH receptor A5 decreases expression EXP Lithium Chloride results in decreased expression of EPHA5 mRNA; Lithium Chloride results in decreased expression of EPHA5 protein CTD PMID:18772502 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CXCL8 mRNA]]; Lithium Chloride inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of CXCL8 protein]] CTD PMID:33396024 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases expression ISO Lithium Chloride results in increased expression of ERBB3 mRNA CTD PMID:23527032 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression ISO Lithium Chloride results in increased expression of ERCC1 mRNA CTD PMID:15711924 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Lithium Chloride co-treated with ESR1 protein] results in increased expression of CTNNB1 protein; Lithium Chloride inhibits the reaction [Estradiol results in increased expression of ESR1 mRNA]; Lithium Chloride inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein]; Lithium Chloride results in decreased phosphorylation of and results in decreased stability of and results in decreased expression of ESR1 protein CTD PMID:16076840 PMID:26990689 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esrrg estrogen-related receptor gamma increases expression ISO Lithium Chloride results in increased expression of ESRRG mRNA CTD PMID:23527032 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases expression
ISO Lithium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]
Lithium Chloride results in decreased expression of F3 mRNA
CTD PMID:15371228 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F5 coagulation factor V increases expression ISO Lithium Chloride results in increased expression of F5 mRNA CTD PMID:23527032 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fam104b family with sequence similarity 104, member B decreases expression ISO Lithium Chloride results in decreased expression of FAM104B mRNA CTD PMID:23527032 NCBI chr  X:19,310,182...19,393,163
Ensembl chr  X:19,349,560...19,378,486
JBrowse link
G Fam90a1 family with sequence similarity 90, member A1 decreases expression ISO Lithium Chloride results in decreased expression of FAM90A1 mRNA CTD PMID:23527032 NCBI chr16:70,098,439...70,106,147
Ensembl chr16:70,098,740...70,101,241
JBrowse link
G Fbxo32 F-box protein 32 decreases expression ISO Lithium Chloride results in decreased expression of FBXO32 mRNA CTD PMID:21832246 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 multiple interactions ISO FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein] CTD PMID:25897075 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fmn2 formin 2 decreases expression ISO Lithium Chloride results in decreased expression of FMN2 mRNA CTD PMID:23527032 NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP Butyrates promotes the reaction [Lithium Chloride results in increased expression of FOS protein] CTD PMID:20346924 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression ISO Lithium Chloride results in increased expression of FXYD5 mRNA CTD PMID:23527032 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in decreased phosphorylation of FYN protein]; Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] CTD PMID:30926361 PMID:32763437 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Fzd3 frizzled class receptor 3 increases expression ISO Lithium Chloride results in increased expression of FZD3 mRNA CTD PMID:20069066 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO Lithium Chloride results in increased expression of FZD4 mRNA CTD PMID:20069066 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression ISO Lithium Chloride results in increased expression of FZD6 mRNA CTD PMID:20069066 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO GATA1 protein results in decreased susceptibility to [Lithium Chloride co-treated with Tretinoin] CTD PMID:19230972 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gbgt1 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) increases expression ISO Lithium Chloride results in increased expression of GBGT1 mRNA CTD PMID:23527032 NCBI chr 3:11,826,131...11,829,745 JBrowse link
G Gcg glucagon multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]
Lithium Chloride results in increased expression of GCG mRNA
CTD PMID:19582394 NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gda guanine deaminase increases expression ISO Lithium Chloride results in increased expression of GDA mRNA CTD PMID:23527032 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO
EXP
Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of GFAP protein; Lithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]
CTD PMID:23872260 PMID:31018114 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gip gastric inhibitory polypeptide multiple interactions
increases expression
ISO [[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter]
Lithium Chloride results in increased expression of GIP mRNA
CTD PMID:19582394 NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Gja1 gap junction protein, alpha 1 affects localization
increases expression
multiple interactions
EXP Lithium Chloride affects the localization of GJA1 protein
Lithium Chloride results in increased expression of GJA1 protein
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein
CTD PMID:18972237 PMID:21177194 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in decreased expression of GLUD1 mRNA] CTD PMID:32494933 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gnaz G protein subunit alpha z decreases expression ISO Lithium Chloride results in decreased expression of GNAZ mRNA CTD PMID:23527032 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
JBrowse link
G Gnpat glyceronephosphate O-acyltransferase decreases expression ISO Lithium Chloride results in decreased expression of GNPAT mRNA CTD PMID:23527032 NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
JBrowse link
G Gramd2a GRAM domain containing 2A increases expression ISO Lithium Chloride results in increased expression of GRAMD2A mRNA CTD PMID:23527032 NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842
JBrowse link
G Gramd2b GRAM domain containing 2B increases expression ISO Lithium Chloride results in increased expression of GRAMD2B mRNA CTD PMID:23527032 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
decreases expression
ISO [[Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA] which affects the susceptibility to Excitatory Amino Acid Agonists; [Lithium Chloride co-treated with Estradiol] results in decreased expression of GRIN1 mRNA
Lithium Chloride results in decreased expression of GRIN1 mRNA
CTD PMID:19285052 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP [Dexamethasone co-treated with Lithium Chloride co-treated with Pilocarpine] affects the expression of GRM1 mRNA CTD PMID:32494933 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grn granulin precursor increases expression ISO Lithium Chloride results in increased expression of GRN mRNA CTD PMID:23527032 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions EXP Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3A protein] CTD PMID:27658547 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
increases expression
decreases activity
decreases expression
increases stability
affects phosphorylation
decreases phosphorylation
ISO
EXP
[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA; [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein; CTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]; GSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]; Lithium Chloride inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in decreased expression of GSK3B protein modified form]; Lithium Chloride inhibits the reaction [celastrol results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein]; Lithium Chloride inhibits the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [quinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein]; Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in decreased expression of and results in increased phosphorylation of GSK3B protein; Lithium Chloride results in increased expression of and results in increased phosphorylation of and results in decreased activity of GSK3B protein; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein; PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]
Lithium Chloride results in increased phosphorylation of GSK3B protein
[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein; [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cisplatin results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium Chloride results in increased expression of GSK3B protein modified form
Lithium Chloride results in decreased expression of GSK3B mRNA
[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein; [Lithium Chloride co-treated with Cisplatin] results in increased phosphorylation of GSK3B protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein; calyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Lithium Chloride inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein]; Lithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein
Lithium Chloride results in increased stability of GSK3B protein
Lithium Chloride affects the phosphorylation of GSK3B protein
Lithium Chloride results in decreased phosphorylation of GSK3B protein
CTD PMID:12813129 PMID:15247282 PMID:15364539 PMID:15585669 PMID:15753396 More... NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA CTD PMID:20118494 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 increases expression ISO Lithium Chloride results in increased expression of HAPLN1 mRNA CTD PMID:23527032 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO Lithium Chloride inhibits the reaction [HDAC1 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [HDAC1 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO Lithium Chloride results in decreased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Hdgfl3 HDGF like 3 decreases expression ISO Lithium Chloride results in decreased expression of HDGFL3 mRNA CTD PMID:15711924 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
JBrowse link
G Hes7 hes family bHLH transcription factor 7 increases expression ISO Lithium Chloride results in increased expression of HES7 mRNA CTD PMID:23326414 NCBI chr10:53,824,124...53,828,350
Ensembl chr10:53,825,574...53,828,097
JBrowse link
G Hist2h4a histone cluster 2 H4 family member A decreases expression ISO Lithium Chloride results in decreased expression of H4C4 mRNA CTD PMID:15711924
G Hmgb1 high mobility group box 1 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of HMGB1 protein] CTD PMID:32494933 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Lithium Chloride results in increased expression of HMOX1 mRNA
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of HMOX1 mRNA; Lithium Chloride promotes the reaction [Sesquiterpenes analog results in increased expression of HMOX1 protein]
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of HMOX1 protein]]; Lithium Chloride promotes the reaction [Cadmium results in increased expression of HMOX1 protein]
CTD PMID:23527032 PMID:26074776 PMID:27658547 PMID:30672058 PMID:33645131 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A decreases expression ISO Lithium Chloride results in decreased expression of HSPA12A mRNA CTD PMID:23527032 NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form CTD PMID:20090934
G Htr2a 5-hydroxytryptamine receptor 2A decreases expression ISO Lithium Chloride results in decreased expression of HTR2A mRNA CTD PMID:23527032 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Ibsp integrin-binding sialoprotein decreases expression ISO Lithium Chloride results in decreased expression of IBSP mRNA CTD PMID:19442631 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Lithium Chloride results in increased expression of ICAM1 mRNA CTD PMID:23527032 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO Lithium Chloride results in decreased expression of ID3 mRNA CTD PMID:15711924 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in increased expression of IDO1 protein] CTD PMID:31760073 NCBI chr16:67,430,684...67,442,459
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Ids iduronate 2-sulfatase increases expression ISO Lithium Chloride results in increased expression of IDS mRNA CTD PMID:23527032 NCBI chr  X:149,025,977...149,046,639
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Ifng interferon gamma increases expression ISO Lithium Chloride results in increased expression of IFNG mRNA CTD PMID:9328138 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA] CTD PMID:19657059 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of IL1B protein
Lithium Chloride results in increased expression of IL1B mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL1B protein
CTD PMID:19010416 PMID:31018114 PMID:33901603 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression ISO Lithium Chloride results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Lithium Chloride results in increased expression of IL6 mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of IL6 protein
CTD PMID:9328138 PMID:31018114 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains increases expression ISO Lithium Chloride results in increased expression of ILRUN mRNA CTD PMID:23527032 NCBI chr20:5,809,931...5,876,231
Ensembl chr20:5,809,936...5,876,012
JBrowse link
G Iqca1 IQ motif containing with AAA domain 1 increases expression ISO Lithium Chloride results in increased expression of IQCA mRNA CTD PMID:23527032 NCBI chr 9:90,626,735...90,742,563
Ensembl chr 9:90,626,744...90,742,618
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Lithium Chloride promotes the reaction [Tretinoin results in increased expression of ITGAM protein] CTD PMID:29743969 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb8 integrin subunit beta 8 increases expression ISO Lithium Chloride results in increased expression of ITGB8 mRNA CTD PMID:15711924 NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Lithium Chloride results in increased expression of JDP2 mRNA CTD PMID:23527032 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Lithium Chloride results in decreased expression of JUN mRNA CTD PMID:26272751 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 decreases expression ISO Lithium Chloride results in decreased expression of KBTBD11 mRNA CTD PMID:23527032 NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736
JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 increases expression ISO Lithium Chloride results in increased expression of KCNK6 mRNA CTD PMID:23527032 NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases expression ISO Lithium Chloride results in increased expression of KCNN4 mRNA CTD PMID:23527032 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Lithium Chloride results in increased expression of KDR mRNA CTD PMID:26272751 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif5a kinesin family member 5A decreases expression ISO Lithium Chloride results in decreased expression of KIF5A mRNA CTD PMID:23527032 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
JBrowse link
G Krt19 keratin 19 increases expression ISO Lithium Chloride results in increased expression of KRT19 mRNA CTD PMID:23527032 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt34 keratin 34 increases expression ISO Lithium Chloride results in increased expression of KRT34 mRNA CTD PMID:15711924 NCBI chr10:84,970,351...84,974,040
Ensembl chr10:84,970,017...84,974,040
JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO Lithium Chloride results in increased expression of LAMC1 mRNA CTD PMID:23527032 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression ISO Lithium Chloride results in increased expression of LCP1 mRNA CTD PMID:23527032 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GCG promoter]; Lithium Chloride promotes the reaction [[LEF1 protein co-treated with CTNNB1 protein] binds to GIP promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GCG promoter]; Lithium Chloride promotes the reaction [LEF1 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 increases expression ISO Lithium Chloride results in increased expression of LGR5 mRNA CTD PMID:33901603 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
JBrowse link
G Lig4 DNA ligase 4 increases expression EXP Lithium Chloride results in increased expression of LIG4 mRNA; Lithium Chloride results in increased expression of LIG4 protein CTD PMID:19285016 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G LOC100125598 metallothionein 1a pseudogene increases expression ISO Lithium Chloride results in increased expression of MT1G mRNA CTD PMID:23527032 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Lrp6 LDL receptor related protein 6 increases expression ISO Lithium Chloride results in increased expression of LRP6 mRNA CTD PMID:20069066 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Maged2 MAGE family member D2 decreases expression ISO Lithium Chloride results in decreased expression of MAGED2 mRNA CTD PMID:23527032 NCBI chr  X:19,733,593...19,741,769
Ensembl chr  X:19,733,597...19,740,477
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation EXP Lithium Chloride affects the phosphorylation of MAPK1 protein CTD PMID:21364661 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk10 mitogen activated protein kinase 10 decreases expression ISO Lithium Chloride results in decreased expression of MAPK10 mRNA CTD PMID:23527032 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation EXP Lithium Chloride affects the phosphorylation of MAPK3 protein CTD PMID:21364661 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
decreases expression
EXP
ISO
[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]]; Lithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of MAPT protein]
Lithium Chloride results in decreased expression of MAPT mRNA
CTD PMID:20937724 PMID:23527032 PMID:27050422 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marveld2 MARVEL domain containing 2 increases expression ISO Lithium Chloride results in increased expression of MARVELD2 mRNA CTD PMID:23527032 NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Lithium Chloride results in increased expression of MCL1 mRNA; Lithium Chloride results in increased expression of MCL1 protein CTD PMID:22493441 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Lithium Chloride results in decreased expression of MCM2 mRNA CTD PMID:17440966 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO Lithium Chloride results in decreased expression of MCM4 mRNA CTD PMID:17440966 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Lithium Chloride results in decreased expression of MCM5 mRNA CTD PMID:17440966 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Lithium Chloride results in decreased expression of MCM6 mRNA CTD PMID:17440966 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Lithium Chloride results in decreased expression of MCM7 mRNA CTD PMID:17440966 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 increases expression ISO Lithium Chloride results in increased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Mex3b mex-3 RNA binding family member B decreases expression ISO Lithium Chloride results in decreased expression of MEX3B mRNA CTD PMID:23527032 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354
JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 decreases expression ISO Lithium Chloride results in decreased expression of MIB1 mRNA CTD PMID:23527032 NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
JBrowse link
G Mir152 microRNA 152 increases expression EXP Lithium Chloride results in increased expression of MIR152 mRNA CTD PMID:19254429 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
JBrowse link
G Mir155 microRNA 155 increases expression EXP Lithium Chloride results in increased expression of MIR155 mRNA CTD PMID:19254429 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir200c microRNA 200c multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] results in increased expression of MIR200C mRNA CTD PMID:31018114 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir221 microRNA 221 increases expression EXP Lithium Chloride results in increased expression of MIR221 mRNA CTD PMID:19254429 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir34a microRNA 34a multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Paraquat results in increased expression of MIR34A mRNA]; [Lithium Chloride results in increased abundance of Lithium] which results in decreased expression of MIR34A mRNA CTD PMID:26074776 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir494 microRNA 494 decreases expression EXP Lithium Chloride results in decreased expression of MIR494 mRNA CTD PMID:19254429 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Lithium Chloride results in increased expression of MITF mRNA CTD PMID:23527032 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mixl1 Mix paired-like homeobox 1 increases expression ISO Lithium Chloride results in increased expression of MIXL1 mRNA CTD PMID:26272751 NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of MKI67 protein]] CTD PMID:15845746 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor decreases expression ISO Lithium Chloride results in decreased expression of MLLT11 mRNA CTD PMID:23527032 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mmab metabolism of cobalamin associated B decreases expression ISO Lithium Chloride results in decreased expression of MMAB mRNA CTD PMID:23527032 NCBI chr12:42,159,109...42,172,496
Ensembl chr12:42,159,089...42,172,490
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
increases expression
ISO MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MMP7 protein]; MALAT1 protein affects the reaction [resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein]]; resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MMP7 protein] CTD PMID:24244343 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mpz myelin protein zero multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of MPZ protein]
Lithium Chloride results in increased expression of MPZ mRNA; Lithium Chloride results in increased expression of MPZ protein
CTD PMID:27788593 NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 decreases expression ISO Lithium Chloride results in decreased expression of MRPL47 mRNA CTD PMID:15711924 NCBI chr 2:115,507,842...115,520,093
Ensembl chr 2:115,500,264...115,518,994
JBrowse link
G Msgn1 mesogenin 1 increases expression ISO Lithium Chloride results in increased expression of MSGN1 mRNA CTD PMID:23326414 NCBI chr 6:33,912,787...33,913,427
Ensembl chr 6:33,912,787...33,913,427
JBrowse link
G Msi1 musashi RNA-binding protein 1 increases expression ISO Lithium Chloride results in increased expression of MSI1 protein CTD PMID:20069066 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein] CTD PMID:30171970 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
EXP
ISO
Lithium Chloride inhibits the reaction [Benzo(a)pyrene results in decreased expression of MYC protein]
Lithium Chloride results in increased expression of MYC mRNA; Lithium Chloride results in increased expression of MYC protein
Arsenic Trioxide inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [Lithium Chloride results in increased expression of MYC protein]; MALAT1 protein affects the reaction [Resveratrol inhibits the reaction [Lithium Chloride results in increased expression of MYC protein]]
CTD PMID:19679347 PMID:22100782 PMID:22493441 PMID:24244343 PMID:26272751 More... NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myct1 myc target 1 increases expression ISO Lithium Chloride results in increased expression of MYCT1 mRNA CTD PMID:23527032 NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410
JBrowse link
G Myh8 myosin heavy chain 8 increases expression ISO Lithium Chloride results in increased expression of MYH8 mRNA CTD PMID:20694829 NCBI chr10:51,963,510...51,993,103
Ensembl chr10:51,963,510...51,993,232
JBrowse link
G Myo1e myosin IE increases expression ISO Lithium Chloride results in increased expression of MYO1E mRNA CTD PMID:26272751 NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
JBrowse link
G Nanog Nanog homeobox increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of NANOG mRNA
SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]
CTD PMID:20069066 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Lithium Chloride results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nes nestin increases expression ISO Lithium Chloride results in increased expression of NES mRNA CTD PMID:26272751 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Neurod1 neuronal differentiation 1 decreases expression ISO Lithium Chloride results in decreased expression of NEUROD1 mRNA CTD PMID:33901603 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 increases activity ISO Lithium Chloride results in increased activity of NFATC3 protein CTD PMID:20694829 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP
ISO
Lithium Chloride affects the reaction [triptolide affects the expression of NFE2L2 protein]; Lithium Chloride inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased activity of NFE2L2 protein]
[Lithium Chloride results in increased abundance of Lithium] which affects the localization of NFE2L2 protein; [Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NFE2L2 mRNA
CTD PMID:26074776 PMID:30926361 PMID:32763437 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation ISO Lithium Chloride results in increased degradation of NFKBIA protein CTD PMID:24085292 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nhlh1 nescient helix loop helix 1 decreases expression ISO Lithium Chloride results in decreased expression of NHLH1 mRNA CTD PMID:23527032 NCBI chr13:84,517,347...84,522,548
Ensembl chr13:84,517,289...84,525,094
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of NKD1 mRNA
Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]; XAV939 inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]
CTD PMID:24534281 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression EXP Lithium Chloride results in increased expression of NOS1 mRNA CTD PMID:9500967 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO Lithium Chloride results in increased expression of NOS2 mRNA CTD PMID:19679347 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Lithium Chloride results in decreased expression of NOTCH1 mRNA CTD PMID:23527032 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Npepl1 aminopeptidase-like 1 increases expression ISO Lithium Chloride results in increased expression of NPEPL1 mRNA CTD PMID:23527032 NCBI chr 3:162,893,891...162,906,492
Ensembl chr 3:162,893,943...162,906,492
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO
EXP
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of NQO1 mRNA
Lithium Chloride affects the reaction [[gastrodin co-treated with rhyncophylline] affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NQO1 protein]]
CTD PMID:26074776 PMID:33645131 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 mRNA]; [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of NR3C1 protein] CTD PMID:32494933 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions
increases expression
EXP CTNNB1 protein affects the reaction [Lithium Chloride results in increased expression of NR4A2 mRNA]; Lithium Chloride inhibits the reaction [Rotenone results in decreased expression of NR4A2 protein]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 promoter]; Lithium Chloride promotes the reaction [CTNNB1 protein binds to NR4A2 protein]
Lithium Chloride results in increased expression of NR4A2 mRNA; Lithium Chloride results in increased expression of NR4A2 protein
CTD PMID:27045591 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO Lithium Chloride results in decreased expression of NRCAM mRNA CTD PMID:26272751 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 decreases expression ISO Lithium Chloride results in decreased expression of NSD2 mRNA CTD PMID:23527032 NCBI chr14:76,833,194...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Ntn1 netrin 1 decreases expression ISO Lithium Chloride results in decreased expression of NTN1 mRNA CTD PMID:23527032 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
JBrowse link
G Ocln occludin decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of OCLN mRNA
Lithium Chloride results in increased expression of OCLN protein
CTD PMID:33901603 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Oprm1 opioid receptor, mu 1 decreases expression EXP Lithium Chloride results in decreased expression of OPRM1 protein CTD PMID:17919468 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP
ISO
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; [Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]; Lithium Chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Lithium Chloride promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein]
Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; Lithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]
CTD PMID:27658547 PMID:28343033 PMID:28886972 PMID:30377735 PMID:31396050 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax3 paired box 3 increases expression ISO Lithium Chloride results in increased expression of PAX3 protein CTD PMID:19101580 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
decreases expression
EXP Lithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]; Lithium Chloride inhibits the reaction [Dexamethasone results in increased expression of PCK1 mRNA]
Lithium Chloride results in decreased expression of PCK1 mRNA
CTD PMID:1371108 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of PCNA protein]]
Lithium Chloride results in increased expression of PCNA protein
CTD PMID:15845746 PMID:27018151 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression ISO Lithium Chloride results in decreased expression of PDE4B mRNA CTD PMID:23527032 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like increases expression ISO Lithium Chloride results in increased expression of PDGFRL mRNA CTD PMID:23527032 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Lithium Chloride results in increased expression of PDIA5 mRNA CTD PMID:23527032 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression ISO Lithium Chloride results in increased expression of PDLIM5 mRNA CTD PMID:15711924 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 multiple interactions EXP [Pilocarpine co-treated with Lithium Chloride co-treated with 3-chloroacetylindole] results in decreased phosphorylation of PEA15 protein; [Pilocarpine co-treated with Lithium Chloride] results in decreased phosphorylation of PEA15 protein CTD PMID:31396050 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Pigr polymeric immunoglobulin receptor decreases expression ISO Lithium Chloride results in decreased expression of PIGR mRNA CTD PMID:33901603 NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions
increases response to substance
affects response to substance
ISO PIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]
PIK3CA protein mutant form results in increased susceptibility to Lithium Chloride
PIK3CA protein affects the susceptibility to Lithium Chloride
CTD PMID:19196980 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Lithium Chloride results in increased expression of PITPNB mRNA CTD PMID:15711924 NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 decreases expression ISO Lithium Chloride results in decreased expression of PLAGL1 mRNA CTD PMID:23527032 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228
JBrowse link
G Plau plasminogen activator, urokinase decreases expression
increases expression
ISO Lithium Chloride results in decreased expression of PLAU mRNA
Lithium Chloride results in increased expression of PLAU mRNA
CTD PMID:15711924 PMID:23527032 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pld1 phospholipase D1 increases expression ISO Lithium Chloride results in increased expression of PLD1 mRNA CTD PMID:23527032 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plekha6 pleckstrin homology domain containing A6 decreases expression ISO Lithium Chloride results in decreased expression of PLEKHA6 mRNA CTD PMID:23527032 NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO Lithium Chloride inhibits the reaction [Chlorpyrifos promotes the reaction [Tretinoin results in increased expression of PLIN1 mRNA]]; Lithium Chloride inhibits the reaction [Tretinoin results in increased expression of PLIN1 mRNA] CTD PMID:28291828 NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
JBrowse link
G Plpp2 phospholipid phosphatase 2 increases expression ISO Lithium Chloride results in increased expression of PLPP2 mRNA CTD PMID:23527032 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Lithium Chloride results in increased expression of PMAIP1 mRNA; Lithium Chloride results in increased expression of PMAIP1 protein CTD PMID:15711924 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmel premelanosome protein increases expression ISO Lithium Chloride results in increased expression of PMEL mRNA CTD PMID:23527032 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions
increases expression
ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of PMP22 protein]
Lithium Chloride results in increased expression of PMP22 mRNA; Lithium Chloride results in increased expression of PMP22 protein
CTD PMID:27788593 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Polr3b RNA polymerase III subunit B decreases expression ISO Lithium Chloride results in decreased expression of POLR3B mRNA CTD PMID:23527032 NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598
JBrowse link
G Popdc3 popeye domain containing 3 increases expression ISO Lithium Chloride results in increased expression of POPDC3 mRNA CTD PMID:15711924 NCBI chr20:48,772,382...48,800,364
Ensembl chr20:48,772,462...48,800,593
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions
increases expression
ISO CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]; CTNNB1 protein promotes the reaction [Lithium Chloride results in increased expression of POU5F1 protein]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]
Lithium Chloride results in increased expression of POU5F1 mRNA; Lithium Chloride results in increased expression of POU5F1 protein
CTD PMID:20069066 PMID:20074550 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Lithium Chloride results in increased expression of PPARG mRNA CTD PMID:23527032 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H increases expression ISO Lithium Chloride results in increased expression of PPM1H mRNA CTD PMID:23527032 NCBI chr 7:58,338,661...58,599,547
Ensembl chr 7:58,338,661...58,599,547
JBrowse link
G Ppp1r14c protein phosphatase 1, regulatory (inhibitor) subunit 14c decreases expression ISO Lithium Chloride results in decreased expression of PPP1R14C mRNA CTD PMID:23527032 NCBI chr 1:39,773,403...39,886,970
Ensembl chr 1:39,773,403...39,886,956
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha increases expression ISO Lithium Chloride results in increased expression of PPP3R1 mRNA CTD PMID:15711924 NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Prr16 proline rich 16 decreases expression ISO Lithium Chloride results in decreased expression of PRR16 mRNA CTD PMID:15711924 NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329
JBrowse link
G Psme1 proteasome activator subunit 1 increases expression ISO Lithium Chloride results in increased expression of PSME1 mRNA CTD PMID:23527032 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
JBrowse link
G Ptges prostaglandin E synthase increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of PTGES protein
[Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]
CTD PMID:19692487 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO
EXP
Lithium Chloride results in increased expression of PTGS2 mRNA; Lithium Chloride results in increased expression of PTGS2 protein CTD PMID:9500967 PMID:15585669 PMID:15711924 PMID:19797860 PMID:24085292 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptx3 pentraxin 3 decreases expression ISO Lithium Chloride results in decreased expression of PTX3 mRNA CTD PMID:23527032 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Purg purine-rich element binding protein G decreases expression ISO Lithium Chloride results in decreased expression of PURG mRNA CTD PMID:23527032 NCBI chr16:58,732,327...58,763,356
Ensembl chr16:58,720,335...58,763,359
JBrowse link
G Pxn paxillin increases expression ISO Lithium Chloride results in increased expression of PXN mRNA CTD PMID:23527032 NCBI chr12:41,060,791...41,107,962
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Pycard PYD and CARD domain containing increases expression ISO Lithium Chloride results in increased expression of PYCARD mRNA CTD PMID:23527032 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rab23 RAB23, member RAS oncogene family increases expression ISO Lithium Chloride results in increased expression of RAB23 mRNA CTD PMID:15711924 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO Lithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of RB1 protein]]
Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of RB1 protein]
CTD PMID:15845746 PMID:22820424 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO Lithium Chloride results in increased expression of RCAN1 mRNA CTD PMID:15711924 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK mRNA; [Lithium Chloride co-treated with Pilocarpine] results in decreased expression of RECK protein CTD PMID:31018114 NCBI chr 5:58,102,915...58,169,513
Ensembl chr 5:58,102,981...58,169,502
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases phosphorylation
increases phosphorylation
EXP
ISO
3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; [Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein; bisindolylmaleimide affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]; U 0126 affects the reaction [[Pilocarpine co-treated with Lithium Chloride] results in increased phosphorylation of RELA protein]
Lithium Chloride results in decreased phosphorylation of RELA protein
Lithium Chloride results in increased phosphorylation of RELA protein
CTD PMID:24085292 PMID:31396050 PMID:33901603 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rexo2 RNA exonuclease 2 increases expression ISO Lithium Chloride results in increased expression of REXO2 mRNA CTD PMID:23527032 NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression ISO Lithium Chloride results in increased expression of RGS4 mRNA; Lithium Chloride results in increased expression of RGS4 protein CTD PMID:15711924 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO FBXW7 protein inhibits the reaction [Lithium Chloride results in increased expression of RICTOR protein]; Lithium Chloride results in increased expression of and results in decreased ubiquitination of RICTOR protein CTD PMID:25897075 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression ISO Lithium Chloride results in increased expression of RND3 mRNA CTD PMID:15711924 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rnf144b ring finger protein 144B multiple interactions
increases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein]; Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein] CTD PMID:29724995 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760
JBrowse link
G Rnf40 ring finger protein 40 increases expression EXP Lithium Chloride results in increased expression of RNF40 protein CTD PMID:21734099 NCBI chr 1:182,202,475...182,217,899
Ensembl chr 1:182,202,600...182,217,241
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO Lithium Chloride results in increased expression of RRAD mRNA CTD PMID:15711924 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Rtn1 reticulon 1 decreases expression ISO Lithium Chloride results in decreased expression of RTN1 mRNA CTD PMID:23527032 NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
JBrowse link
G S100a3 S100 calcium binding protein A3 increases expression ISO Lithium Chloride results in increased expression of S100A3 mRNA CTD PMID:23527032 NCBI chr 2:176,034,283...176,089,702
Ensembl chr 2:176,049,520...176,089,702
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity ISO Lithium Chloride results in decreased activity of SCN5A protein CTD PMID:16144991 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha increases expression ISO Lithium Chloride results in increased expression of SCNN1A mRNA CTD PMID:23527032 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression ISO Lithium Chloride results in increased expression of SCPEP1 mRNA CTD PMID:23527032 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of SFRP2 mRNA
SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of CTNNB1 mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of NANOG mRNA]; SFRP2 protein affects the reaction [Lithium Chloride results in increased expression of POU5F1 mRNA]
CTD PMID:20069066 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Shf Src homology 2 domain containing F decreases expression ISO Lithium Chloride results in decreased expression of SHF mRNA CTD PMID:23527032 NCBI chr 3:109,296,517...109,316,315
Ensembl chr 3:109,296,784...109,316,328
JBrowse link
G Shh sonic hedgehog signaling molecule decreases expression ISO Lithium Chloride results in decreased expression of SHH mRNA CTD PMID:26272751 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Shpk sedoheptulokinase increases expression ISO Lithium Chloride results in increased expression of SHPK mRNA CTD PMID:23527032 NCBI chr10:57,817,551...57,841,981
Ensembl chr10:57,817,629...57,841,980
JBrowse link
G Six1 SIX homeobox 1 increases expression
increases response to substance
ISO Lithium Chloride results in increased expression of SIX1 mRNA; Lithium Chloride results in increased expression of SIX1 protein
SIX1 protein results in increased susceptibility to Lithium Chloride
CTD PMID:19101580 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of SLC12A1 protein
PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]
CTD PMID:19692487 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc20a1 solute carrier family 20 member 1 increases expression ISO Lithium Chloride results in increased expression of SLC20A1 mRNA CTD PMID:15711924 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Lithium Chloride results in increased expression of SLC3A2 mRNA CTD PMID:15711924 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression ISO Lithium Chloride results in increased expression of SLC5A3 mRNA CTD PMID:15711924 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases degradation
multiple interactions
ISO Lithium Chloride results in decreased degradation of SNAI1 protein
[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein
[Lithium Chloride results in decreased degradation of SNAI1 protein] which affects the expression of CDH1 protein
CTD PMID:19440036 PMID:20348013 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snca synuclein alpha increases expression ISO Lithium Chloride results in increased expression of SNCA mRNA CTD PMID:23527032 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Dextroamphetamine results in decreased activity of SOD2 protein] CTD PMID:31760073 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO Lithium Chloride results in decreased expression of SPAG5 mRNA CTD PMID:23527032 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Sqor sulfide quinone oxidoreductase increases expression ISO Lithium Chloride results in increased expression of SQOR mRNA CTD PMID:23527032 NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Lithium Chloride promotes the reaction [Cisplatin results in decreased expression of SQSTM1 protein] CTD PMID:31220555 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Stard7 StAR-related lipid transfer domain containing 7 multiple interactions ISO [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA; [Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein CTD PMID:19679347 NCBI chr 3:114,487,163...114,515,825
Ensembl chr 3:114,485,600...114,515,813
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases expression ISO Lithium Chloride results in increased expression of STAT6 mRNA CTD PMID:23527032 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 increases expression ISO Lithium Chloride results in increased expression of TARS1 mRNA CTD PMID:15711924 NCBI chr 2:60,368,251...60,387,733
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression ISO Lithium Chloride results in decreased expression of TBC1D8 mRNA CTD PMID:15711924 NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409
JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]; Resveratrol inhibits the reaction [Lithium Chloride results in increased activity of [TCF4 protein co-treated with CTNNB1 protein]] CTD PMID:22935447 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tcf7l2 transcription factor 7 like 2 multiple interactions ISO Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GCG promoter]; Lithium Chloride inhibits the reaction [TCF7L2 protein binds to GIP promoter] CTD PMID:19582394 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Lithium Chloride results in increased expression of TGFBR2 mRNA CTD PMID:23527032 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO Lithium Chloride results in decreased expression of TJP1 mRNA CTD PMID:33901603 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of TLR4 mRNA] CTD PMID:32494933 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO Lithium Chloride results in increased expression of TM4SF1 mRNA CTD PMID:15711924 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression ISO Lithium Chloride results in increased expression of TMPRSS2 mRNA CTD PMID:23527032 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715
JBrowse link
G Tnc tenascin C increases expression ISO Lithium Chloride results in increased expression of TNC mRNA CTD PMID:15711924 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP
ISO
Lithium Chloride results in increased expression of TNF protein
Lithium Chloride results in increased expression of TNF mRNA
[Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF mRNA; [Lithium Chloride co-treated with Pilocarpine] results in increased expression of TNF protein; Rosiglitazone inhibits the reaction [Lithium Chloride results in increased expression of TNF protein]
CTD PMID:18455351 PMID:31018114 PMID:33901603 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type increases expression ISO Lithium Chloride results in increased expression of TNNC1 mRNA CTD PMID:23527032 NCBI chr16:6,400,801...6,405,419
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression ISO Lithium Chloride results in increased expression of TNNT1 mRNA CTD PMID:23527032 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Top3a DNA topoisomerase III alpha decreases expression ISO Lithium Chloride results in decreased expression of TOP3A mRNA CTD PMID:23527032 NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO Lithium Chloride results in increased expression of TP53 protein
Lithium Chloride results in decreased degradation of and results in increased expression of TRP53 protein
CTD PMID:16055726 PMID:17210701 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 increases expression ISO Lithium Chloride results in increased expression of TP63 mRNA CTD PMID:23527032 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tpd52l1 TPD52 like 1 increases expression ISO Lithium Chloride results in increased expression of TPD52L1 mRNA CTD PMID:23527032 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Tph1 tryptophan hydroxylase 1 decreases expression ISO Lithium Chloride results in decreased expression of TPH1 mRNA CTD PMID:33901603 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
G Tph2 tryptophan hydroxylase 2 decreases expression EXP Lithium Chloride results in decreased expression of TPH2 mRNA; Lithium Chloride results in decreased expression of TPH2 protein CTD PMID:19840776 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
JBrowse link
G Tpm1 tropomyosin 1 increases expression ISO Lithium Chloride results in increased expression of TPM1 mRNA CTD PMID:23527032 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Lithium Chloride results in increased expression of TRIB3 mRNA CTD PMID:23527032 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim6 tripartite motif containing 6 increases expression ISO Lithium Chloride results in increased expression of TRIM6 mRNA CTD PMID:23527032 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Lithium Chloride results in increased abundance of Lithium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression
multiple interactions
ISO Lithium Chloride results in decreased expression of UGCG mRNA
[Lithium Chloride results in increased abundance of Lithium] which results in increased expression of UGCG mRNA
CTD PMID:15711924 PMID:26074776 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Utp3 UTP3, small subunit processome component increases expression ISO Lithium Chloride results in increased expression of UTP3 mRNA CTD PMID:27226553 NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO Lithium Chloride results in increased expression of VCAM1 mRNA CTD PMID:33901603 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Lithium Chloride results in increased expression of VEGFA protein
Lithium Chloride results in increased expression of VEGFA mRNA
CTD PMID:20696143 PMID:26272751 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin increases expression
multiple interactions
decreases expression
EXP
ISO
Lithium Chloride results in increased expression of VIM protein
Lithium Chloride inhibits the reaction [thymoquinone results in decreased expression of VIM protein]
Lithium Chloride results in decreased expression of VIM mRNA
CTD PMID:8773480 PMID:23527032 PMID:32112862 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vpreb1 V-set pre-B cell surrogate light chain 1 increases expression ISO Lithium Chloride results in increased expression of VPREB1 mRNA CTD PMID:27226553 NCBI chr11:84,126,969...84,127,846
Ensembl chr11:84,126,969...84,127,846
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO Lithium Chloride inhibits the reaction [quinocetone results in decreased expression of WNT1 protein] CTD PMID:28343033 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt3 Wnt family member 3 decreases expression ISO Lithium Chloride results in decreased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 increases expression EXP Lithium Chloride results in increased expression of XRCC4 mRNA CTD PMID:19285016 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
G Ybx1 Y box binding protein 1 decreases expression ISO Lithium Chloride results in decreased expression of YBX1 mRNA CTD PMID:23527032 NCBI chr 5:132,882,137...132,899,108
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Zfp207 zinc finger protein 207 increases expression ISO Lithium Chloride results in increased expression of ZNF207 mRNA CTD PMID:15711924 NCBI chr10:65,385,823...65,397,591
Ensembl chr10:65,385,740...65,397,386
JBrowse link
G Zfp423 zinc finger protein 423 decreases expression ISO Lithium Chloride results in decreased expression of ZNF423 mRNA CTD PMID:23527032 NCBI chr19:19,111,538...19,407,371
Ensembl chr19:19,110,238...19,407,373
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 decreases expression ISO Lithium Chloride results in decreased expression of ZMYND8 mRNA CTD PMID:15711924 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
JBrowse link
G Zscan22 zinc finger and SCAN domain containing 22 decreases expression ISO Lithium Chloride results in decreased expression of ZSCAN22 mRNA CTD PMID:23527032 NCBI chr 1:73,516,335...73,527,766
Ensembl chr 1:73,516,395...73,527,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    chemical entity 20058
      atom 20056
        metal atom 17548
          alkali metal atom 11576
            lithium atom 535
              lithium molecular entity + 348
              lithium-6 atom 0
              lithium-7 atom 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  metal atom 17548
                    alkali metal atom 11576
                      lithium atom 535
                        lithium molecular entity + 348
                        lithium-6 atom 0
                        lithium-7 atom 0
paths to the root