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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetate
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Accession:CHEBI:30089 term browser browse the term
Definition:A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.
Synonyms:related_synonym: ACETATE ION;   Azetat;   CH3-COO(-);   Ethanoat;   Formula=C2H3O2;   InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1;   InChIKey=QTBSBXVTEAMEQO-UHFFFAOYSA-M;   MeCO2 anion;   SMILES=CC([O-])=O;   acetic acid, ion(1-);   ethanoate
 alt_id: CHEBI:13704;   CHEBI:22165;   CHEBI:40480
 xref: Beilstein:1901470;   CAS:71-50-1;   DrugBank:DB03166;   Gmelin:1379;   KEGG:C00033;   MetaCyc:ACET;   PDBeChem:ACT;   PMID:17190852;   PMID:22211106;   PMID:22371380;   Reaxys:1901470;   UM-BBD_compID:c0050;   Wikipedia:Acetate
 cyclic_relationship: is_conjugate_base_of CHEBI:15366


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acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor increases secretion EXP Acetate increases secretion of Tnf protein from Kupffer cells RGD PMID:19299582 RGD:9585771 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
GGTI-2133 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of AKT1 protein] CTD PMID:19299917 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK1 protein] CTD PMID:19299917 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK3 protein] CTD PMID:19299917 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP GGTI-2133 inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]; GGTI-2133 inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein] CTD PMID:19299917 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases geranoylation ISO GGTI-2133 results in decreased geranoylation of RAP1A protein CTD PMID:25578243 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
lead tetraacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein decreases expression ISO lead tetraacetate results in decreased expression of APP mRNA CTD PMID:20865013 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO lead tetraacetate results in decreased expression of MAPT mRNA CTD PMID:20865013 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Nrxn1 neurexin 1 decreases expression ISO lead tetraacetate results in decreased expression of NRXN1 mRNA CTD PMID:20865013 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Prnp prion protein decreases expression ISO lead tetraacetate results in decreased expression of PRNP mRNA CTD PMID:20865013 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Syp synaptophysin decreases expression ISO lead tetraacetate results in decreased expression of SYP mRNA CTD PMID:20865013 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO lead tetraacetate results in decreased expression of TUBB3 mRNA CTD PMID:20865013 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
sodium acetate trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of ADA protein] CTD PMID:31857090 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Sodium Acetate co-treated with acetic anhydride] results in increased acetylation of APOB protein CTD PMID:11304478 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:31621310 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:31621310 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of GGT1 protein] CTD PMID:31857090 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein] CTD PMID:17615583 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] CTD PMID:17615583 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein] CTD PMID:17615583 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein] CTD PMID:31857090 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      molecular entity 19819
        ion 16059
          anion 14973
            organic anion 3056
              carboxylic acid anion 2396
                monocarboxylic acid anion 1500
                  acetate 22
                    (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetate + 0
                    (2,6-dihydroxyphenyl)acetate 0
                    (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate 0
                    1-palmityl-2-acetyl-sn-glycero-3-phosphate(2-) 0
                    4-chlorophenylacetate 0
                    4-hydroxyphenylacetate 0
                    calcium acetate + 0
                    chloroacetate 0
                    dichloroacetate 0
                    difluoroacetate 0
                    ethylammonium acetate 0
                    fluoroacetate + 0
                    glycolate + 0
                    guanidine acetate 0
                    haloacetate(1-) + 0
                    homogentisate 0
                    lead tetraacetate 6
                    lithium acetate 0
                    mandelate + 0
                    phenylacetate + 0
                    potassium acetate 0
                    sodium acetate + 10
                    trichloroacetate 0
                    trifluoroacetate + 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic ion 9147
                              organic anion 3056
                                carboxylic acid anion 2396
                                  monocarboxylic acid anion 1500
                                    acetate 22
                                      (2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl)acetate + 0
                                      (2,6-dihydroxyphenyl)acetate 0
                                      (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate 0
                                      1-palmityl-2-acetyl-sn-glycero-3-phosphate(2-) 0
                                      4-chlorophenylacetate 0
                                      4-hydroxyphenylacetate 0
                                      calcium acetate + 0
                                      chloroacetate 0
                                      dichloroacetate 0
                                      difluoroacetate 0
                                      ethylammonium acetate 0
                                      fluoroacetate + 0
                                      glycolate + 0
                                      guanidine acetate 0
                                      haloacetate(1-) + 0
                                      homogentisate 0
                                      lead tetraacetate 6
                                      lithium acetate 0
                                      mandelate + 0
                                      phenylacetate + 0
                                      potassium acetate 0
                                      sodium acetate + 10
                                      trichloroacetate 0
                                      trifluoroacetate + 5
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