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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beclomethasone
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Accession:CHEBI:3001 term browser browse the term
Definition:A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively.
Synonyms:exact_synonym: (11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
 related_synonym: 9-chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione;   9alpha-chloro-16beta-methylprednisolone;   Formula=C22H29ClO5;   InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1;   InChIKey=NBMKJKDGKREAPL-DVTGEIKXSA-N;   SMILES=[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C;   beclometasona;   beclometasone;   beclometasonum
 xref: Beilstein:5640546;   CAS:4419-39-0;   DrugBank:DB00394;   KEGG:C06842;   KEGG:D07495
 xref_mesh: MESH:D001507
 xref: Patent:GB912378;   Reaxys:5640546



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beclomethasone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
increases secretion
ISO Beclomethasone inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Beclomethasone inhibits the reaction [ABCB1 protein results in increased export of fluorexon]; Elacridar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]; valspodar inhibits the reaction [ABCB1 protein results in increased secretion of Beclomethasone]
Beclomethasone results in increased expression of ABCB1 mRNA; Beclomethasone results in increased expression of ABCB1 protein
CTD PMID:15370884 PMID:16442095 PMID:22464980 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Beclomethasone results in increased expression of ABCB4 mRNA CTD PMID:15370884 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Beclomethasone results in increased expression of ABCC1 mRNA CTD PMID:15370884 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases activity
ISO Beclomethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]; Beclomethasone inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]
Beclomethasone results in increased activity of ABCG2 protein
CTD PMID:15365089 PMID:16442095 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases activity ISO Beclomethasone results in decreased activity of ACP5 protein CTD PMID:8429434 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression ISO Beclomethasone results in increased expression of ADRB2 mRNA CTD PMID:9032216 PMID:15679717 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Bdkrb1 bradykinin receptor B1 decreases expression ISO Beclomethasone results in decreased expression of BDKRB1 mRNA CTD PMID:18039523 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Beclomethasone results in decreased expression of BGLAP protein CTD PMID:7746775 PMID:9232087 PMID:9544892 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Casp9 caspase 9 increases activity ISO Beclomethasone results in increased activity of CASP9 protein CTD PMID:11734450 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression ISO Beclomethasone results in increased expression of CAT protein CTD PMID:10445599 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO Beclomethasone inhibits the reaction [IL13 protein results in increased expression of CCL11 protein] CTD PMID:17988555 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Beclomethasone results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Beclomethasone results in increased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Beclomethasone results in increased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
decreases expression
ISO [Beclomethasone co-treated with Albuterol] results in decreased secretion of CCL5 protein; [Beclomethasone co-treated with Formoterol Fumarate] results in decreased secretion of CCL5 protein; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]
Beclomethasone results in decreased expression of CCL5 mRNA; Beclomethasone results in decreased expression of CCL5 protein
CTD PMID:8534483 PMID:10903220 PMID:14643170 PMID:15679717 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Albuterol promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]; Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]] CTD PMID:18076728 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
decreases secretion
increases activity
ISO [Beclomethasone co-treated with Albuterol] results in decreased secretion of CSF2 protein; [Beclomethasone co-treated with Formoterol Fumarate] results in decreased secretion of CSF2 protein; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of CSF2 mRNA]; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of CSF2 protein]; Beclomethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]
Beclomethasone results in decreased secretion of CSF2 protein
Beclomethasone results in increased activity of CSF2 protein
CTD PMID:7545059 PMID:10460758 PMID:10868704 PMID:11167953 PMID:11730731 More... NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases secretion ISO Beclomethasone results in decreased secretion of CXCL10 protein CTD PMID:17996064 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression ISO Beclomethasone results in decreased expression of CYP2S1 mRNA CTD PMID:22155357 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
increases expression
ISO 1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Paraoxon inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Physostigmine inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] CTD PMID:12538830 PMID:23512537 PMID:24555085 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Epx eosinophil peroxidase multiple interactions EXP Beclomethasone inhibits the reaction [sephadex results in increased expression of EPX protein] CTD PMID:10850854 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
JBrowse link
G Fcer1g Fc epsilon receptor Ig decreases expression EXP Beclomethasone results in decreased expression of FCER1G protein CTD PMID:1834581 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
decreases activity
ISO [Beclomethasone co-treated with Albuterol] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]; [Beclomethasone co-treated with Formoterol Fumarate] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]; Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]; Albuterol promotes the reaction [Beclomethasone results in decreased activity of FGF2 protein]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]; Formoterol Fumarate promotes the reaction [Beclomethasone results in decreased activity of FGF2 protein] CTD PMID:18076728 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Beclomethasone co-treated with Albuterol] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein]; [Beclomethasone co-treated with Formoterol Fumarate] inhibits the reaction [FGF2 protein results in increased secretion of FN1 protein] CTD PMID:18076728 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Beclomethasone results in decreased expression of FOS protein CTD PMID:9797757 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Ggt5 gamma-glutamyltransferase 5 increases activity
increases expression
multiple interactions
ISO Beclomethasone results in increased activity of GGT5 protein
Beclomethasone results in increased expression of GGT5 mRNA
[Beclomethasone results in increased activity of GGT5 protein] which results in increased metabolism of Leukotriene C4
CTD PMID:11447392 NCBI chr20:13,043,255...13,071,523 JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases metabolic processing ISO HSD11B2 protein results in increased metabolism of Beclomethasone CTD PMID:16549198 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Beclomethasone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:9150321 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 decreases secretion ISO Beclomethasone results in decreased secretion of IL10 protein CTD PMID:9819297 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 multiple interactions
increases activity
ISO Beclomethasone inhibits the reaction [IL13 protein results in increased expression of CCL11 protein]; Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 mRNA]; Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 protein]
Beclomethasone inhibits the reaction [OVAL protein results in increased expression of IL13 protein]
Beclomethasone results in increased activity of IL13 protein
CTD PMID:17988555 PMID:29986831 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases secretion
decreases expression
ISO Beclomethasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]; Beclomethasone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Beclomethasone results in decreased secretion of IL1B protein
Beclomethasone results in decreased expression of IL1B protein
CTD PMID:7545059 PMID:9176529 PMID:9371735 PMID:10460758 PMID:15337628 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression ISO Beclomethasone results in decreased expression of IL1RN protein CTD PMID:11015126 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression ISO Beclomethasone results in decreased expression of IL2RA protein CTD PMID:8111605 PMID:9314351 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il3 interleukin 3 multiple interactions ISO Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL3 mRNA]; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL3 protein] CTD PMID:11167953 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
ISO Albuterol promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]; Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]
Beclomethasone results in decreased expression of IL4 protein
CTD PMID:7988651 PMID:18076728 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions
decreases expression
ISO Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL5 mRNA]; Beclomethasone inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]
Beclomethasone results in decreased expression of IL5 protein
CTD PMID:7988651 PMID:10813552 PMID:11167953 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 mRNA]; Beclomethasone inhibits the reaction [IL13 protein results in increased expression of IL6 protein] CTD PMID:17988555 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ltf lactotransferrin multiple interactions
decreases secretion
ISO Beclomethasone inhibits the reaction [methylcholine results in increased secretion of LTF protein]
Beclomethasone results in decreased secretion of LTF protein
CTD PMID:11112886 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin increases response to substance ISO MEFV mutant form results in increased susceptibility to Beclomethasone CTD PMID:20828792 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein] CTD PMID:10455257 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]
Beclomethasone results in decreased expression of MMP9 protein
CTD PMID:10452757 PMID:10455257 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO Beclomethasone results in decreased expression of NOS2 protein CTD PMID:12668791 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Beclomethasone results in increased activity of NR1I2 protein CTD PMID:21068194 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects localization
increases expression
affects binding
multiple interactions
increases activity
ISO
EXP
Beclomethasone affects the localization of NR3C1 protein
Beclomethasone results in increased expression of NR3C1 mRNA
Beclomethasone binds to NR3C1 protein
[Beclomethasone co-treated with Albuterol] affects the localization of NR3C1 protein; [Beclomethasone co-treated with Formoterol Fumarate] affects the localization of NR3C1 protein; Beclomethasone affects the localization of and results in increased activity of NR3C1 protein; Beclomethasone binds to and results in increased activity of NR3C1 protein
Beclomethasone results in increased activity of NR3C1 protein
CTD PMID:16814 PMID:2207292 PMID:15362971 PMID:15679717 PMID:15860753 More... NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases activity ISO Beclomethasone results in increased activity of NR3C2 protein CTD PMID:15362971 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Pla1a phospholipase A1 member A multiple interactions ISO Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA1A mRNA] CTD PMID:20573295 NCBI chr11:62,320,117...62,357,779
Ensembl chr11:62,320,493...62,357,779
JBrowse link
G Pla2g4a phospholipase A2 group IVA decreases activity
multiple interactions
ISO Beclomethasone results in decreased activity of PLA2G4A protein
Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]
CTD PMID:15337628 PMID:20573295 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A multiple interactions EXP Beclomethasone inhibits the reaction [Acetylcholine results in increased phosphorylation of PPP1R14A protein] CTD PMID:18577381 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP Beclomethasone inhibits the reaction [[[Antigens, Bacterial co-treated with Allergens] results in increased expression of and results in increased activity of RHOA protein] which results in increased susceptibility to Acetylcholine]; Beclomethasone inhibits the reaction [[Antigens, Bacterial co-treated with Allergens] results in increased expression of and results in increased activity of RHOA protein]; Beclomethasone inhibits the reaction [[Antigens, Bacterial co-treated with Allergens] results in increased expression of RHOA mRNA] CTD PMID:18391481 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rnase2 ribonuclease A family member 2 decreases expression ISO Beclomethasone results in decreased expression of RNASE2 protein CTD PMID:12166584 NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479
JBrowse link
G Rnase3 ribonuclease A family member 3 multiple interactions
decreases expression
ISO [Salmeterol Xinafoate co-treated with Beclomethasone] affects the reaction [Allergens results in increased expression of RNASE3 protein]; Beclomethasone affects the reaction [Allergens results in increased expression of RNASE3 protein]
Beclomethasone results in decreased expression of RNASE3 protein
CTD PMID:1443864 PMID:10513351 PMID:10573242 PMID:12166584 PMID:12587966 More... NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790
JBrowse link
G Sele selectin E multiple interactions ISO Beclomethasone inhibits the reaction [IL1B protein results in increased expression of SELE mRNA] CTD PMID:9371735 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Beclomethasone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions ISO Albuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]]; Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]; Formoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of THY1 protein]] CTD PMID:18076728 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Beclomethasone results in increased expression of TIMP1 protein CTD PMID:10452757 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases secretion
ISO Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Beclomethasone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]
Beclomethasone results in decreased secretion of TNF protein
CTD PMID:8937731 PMID:9150321 PMID:9819297 PMID:10100995 PMID:10903220 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Beclomethasone inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:10100995 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Beclomethasone results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        anti-inflammatory agent 15841
          anti-inflammatory drug 13634
            beclomethasone 58
              beclomethasone dipropionate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      ketone 16957
                                        oxo steroid 10282
                                          3-oxo steroid 9887
                                            3-oxo-Delta(4) steroid 9122
                                              progesterone 2717
                                                Delta(1)-progesterone 238
                                                  prednisolone 232
                                                    beclomethasone 58
                                                      beclomethasone dipropionate 0
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