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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:teicoplanin
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Accession:CHEBI:29687 term browser browse the term
Definition:A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis.
Synonyms:related_synonym: Targocid;   antibiotic 8327A;   teicoplanina;   teicoplanine;   teicoplaninum
 xref: CAS:61036-62-2;   DrugBank:DB06149;   KEGG:C15820;   KEGG:D02142
 xref_mesh: MESH:D017334
 xref: PMID:1416858;   PMID:24506456;   PMID:24693468;   PMID:25190719;   PMID:25218156;   PMID:25224001;   PMID:25358800;   PMID:25616054;   PMID:25726436;   Reaxys:8196734;   Wikipedia:Teicoplanin


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teicoplanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsl cathepsin L decreases activity ISO Teicoplanin results in decreased activity of CTSL protein CTD PMID:26953343 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Teicoplanin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:165,966,128...165,982,327 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        antimicrobial agent 17383
          teicoplanin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic group 18537
                              organic divalent group 18528
                                organodiyl group 18528
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18113
                                        carboacyl group 17377
                                          univalent carboacyl group 17377
                                            carbamoyl group 17164
                                              carboxamide 17164
                                                peptide 9399
                                                  glycopeptide 1492
                                                    teicoplanin A3-1 2
                                                      teicoplanin A2 2
                                                        teicoplanin A2-1 2
                                                          teicoplanin 2
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