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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:BQ 485
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Accession:CHEBI:2966 term browser browse the term
Definition:A peptide that has formula C35H44N6O5.
Synonyms:related_synonym: Formula=C35H44N6O5;   InChI=1S/C35H44N6O5/c1-22(2)17-29(40-35(46)41-15-9-3-4-10-16-41)32(42)38-30(18-23-20-36-27-13-7-5-11-25(23)27)33(43)39-31(34(44)45)19-24-21-37-28-14-8-6-12-26(24)28/h5-8,11-14,20-22,29-31,36-37H,3-4,9-10,15-19H2,1-2H3,(H,38,42)(H,39,43)(H,40,46)(H,44,45)/t29-,30+,31+/m0/s1;   InChIKey=ZBJNAHVLKNFOPP-OJDZSJEKSA-N;   Perhydroazepino-N-carbonyl-L-Leu-D-Trp-D-Trp;   SMILES=CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O
 xref: CAS:141594-26-5;   KEGG:C11362
 xref_mesh: MESH:C083116


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BQ 485 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [BQ 485 binds to and results in decreased activity of EDNRA protein] which results in decreased expression of BCL2 protein CTD PMID:14736733 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP BQ 485 inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:16391241 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [BQ 485 binds to and results in decreased activity of EDNRA protein] which results in decreased expression of BCL2 protein CTD PMID:14736733 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19765
    chemical entity 19763
      group 19727
        organic group 18856
          amino-acid residue 9550
            peptide 9549
              BQ 485 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19765
    subatomic particle 19763
      composite particle 19763
        hadron 19763
          baryon 19763
            nucleon 19763
              atomic nucleus 19763
                atom 19763
                  main group element atom 19712
                    p-block element atom 19712
                      carbon group element atom 19658
                        carbon atom 19654
                          organic molecular entity 19654
                            organic group 18856
                              organic divalent group 18842
                                organodiyl group 18842
                                  carbonyl group 18807
                                    carbonyl compound 18807
                                      carboxylic acid 18523
                                        carboacyl group 17654
                                          univalent carboacyl group 17654
                                            carbamoyl group 17496
                                              carboxamide 17496
                                                peptide 9549
                                                  BQ 485 3
paths to the root