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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:gold atom
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Accession:CHEBI:29287 term browser browse the term
Definition:A copper group element atom that has formula Au.
Synonyms:related_synonym: 79Au;   Au;   Formula=Au;   Gold;   InChI=1S/Au;   InChIKey=PCHJSUWPFVWCPO-UHFFFAOYSA-N;   SMILES=[Au];   aurum;   or;   oro
 xref: CAS:7440-57-5
 xref_mesh: MESH:D006046
 xref: WebElements:Au



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gold atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of AASS mRNA CTD PMID:28433809 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA CTD PMID:28433809 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ABCC1 mRNA CTD PMID:28433809 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ABL1 mRNA CTD PMID:28433809 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ACADS mRNA CTD PMID:28433809 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ACADVL mRNA CTD PMID:28433809 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Aco1 aconitase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of ACO1 mRNA CTD PMID:28433809 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 decreases expression
multiple interactions
ISO Gold analog results in decreased expression of ACO2 protein
[Polyethyleneimine binds to Gold] which results in increased expression of ACO2 mRNA
CTD PMID:24780912 PMID:28433809 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ACOX1 mRNA CTD PMID:19695318 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acp1 acid phosphatase 1 decreases expression ISO Gold results in decreased expression of ACP1 mRNA CTD PMID:25523186 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
JBrowse link
G Acvr1c activin A receptor type 1C decreases expression ISO Gold results in decreased expression of ACVR1C mRNA CTD PMID:25523186 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 increases expression ISO Gold results in increased expression of ADAM28 mRNA CTD PMID:29705079 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression ISO Gold results in decreased expression of ADH5 mRNA CTD PMID:25523186 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ADIPOR2 mRNA CTD PMID:19695318 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of ADRA1B mRNA CTD PMID:19695318 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of ADRB2 mRNA CTD PMID:19695318 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Gold results in increased expression of AIFM1 protein CTD PMID:25462594 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 decreases expression ISO Gold results in decreased expression of AIMP1 mRNA CTD PMID:25523186 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Gold results in decreased expression of AK3 mRNA CTD PMID:25523186 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Akap13 A-kinase anchoring protein 13 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of AKAP13 mRNA CTD PMID:19695318 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Gold results in increased expression of AKR1B10 mRNA CTD PMID:29705079 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Gold results in increased expression of AKR1C2 mRNA CTD PMID:29705079 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Gold results in increased expression of AKR1C3 mRNA CTD PMID:29705079 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of AKT1 protein CTD PMID:27470402 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions ISO ALB protein results in increased uptake of [Polyethylene Glycols binds to Gold]; ALB protein results in increased uptake of [Polyethyleneimine binds to Gold]; ALB protein results in increased uptake of [Thioctic Acid binds to Gold] CTD PMID:28433809 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Anxa5 annexin A5 increases expression ISO Gold analog results in increased expression of ANXA5 protein CTD PMID:24780912 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein CTD PMID:27470402 PMID:28433809 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of APOA4 mRNA CTD PMID:19695318 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO Gold analog results in decreased expression of APRT protein CTD PMID:24780912 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Aqp4 aquaporin 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of AQP4 mRNA CTD PMID:28433809 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 decreases expression ISO Gold results in decreased expression of ARL1 mRNA CTD PMID:25523186 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B decreases expression ISO Gold results in decreased expression of ARL5B mRNA CTD PMID:25523186 NCBI chr17:77,955,749...77,983,745
Ensembl chr17:77,955,818...77,979,854
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ARNTL mRNA CTD PMID:19695318 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arsg arylsulfatase G multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ARSG mRNA CTD PMID:19695318 NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
JBrowse link
G Atf1 activating transcription factor 1 decreases expression ISO Gold results in decreased expression of ATF1 mRNA CTD PMID:25523186 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ATF4 mRNA CTD PMID:28433809 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases cleavage ISO Gold analog results in increased cleavage of ATF6 protein CTD PMID:26551149 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase decreases expression ISO Gold analog results in decreased expression of ATIC protein CTD PMID:24780912 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atl2 atlastin GTPase 2 decreases expression ISO Gold results in decreased expression of ATL2 mRNA CTD PMID:25523186 NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ATP2B1 mRNA CTD PMID:19695318 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions ISO Gold analog results in increased expression of and results in decreased phosphorylation of ATP5B protein CTD PMID:24780912 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of BACE1 mRNA CTD PMID:19695318 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in increased expression of BAD protein CTD PMID:27470402 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of BAIAP2 mRNA CTD PMID:19695318 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Gold results in increased expression of BAK1 mRNA CTD PMID:22178767 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of BAX protein; [Gold analog co-treated with Platinum] results in increased expression of BAX mRNA; [Polyethyleneimine binds to Gold] which results in decreased expression of BAX mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of BAX protein
[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of BAX protein
Gold results in increased expression of BAX mRNA
CTD PMID:21621595 PMID:22178767 PMID:25846798 PMID:27470402 PMID:27836789 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor decreases expression ISO Gold results in decreased expression of BCAS2 mRNA CTD PMID:25523186 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP
[Gold analog co-treated with Platinum] results in decreased expression of BCL2 mRNA; [Quercetin analog co-treated with Gold analog] results in decreased expression of BCL2 protein
[Gold binds to NKCT1 protein, Naja kaouthia] which results in decreased expression of BCL2 protein
CTD PMID:25846798 PMID:27470402 PMID:27836789 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of BCL2L1 mRNA CTD PMID:28433809 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Gold results in decreased expression of BIRC2 mRNA CTD PMID:25523186 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Gold results in decreased expression of BIRC3 mRNA CTD PMID:25523186 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger decreases expression ISO Gold results in decreased expression of BMI1 mRNA CTD PMID:25523186 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of BRCA1 mRNA CTD PMID:28433809 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of BRCA2 mRNA CTD PMID:28433809 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Bves blood vessel epicardial substance increases expression ISO Gold results in increased expression of BVES mRNA CTD PMID:29705079 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
JBrowse link
G C1d C1D nuclear receptor corepressor decreases expression ISO Gold results in decreased expression of C1D mRNA CTD PMID:25523186 NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
JBrowse link
G C3 complement C3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of C3 mRNA CTD PMID:28433809 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Ca13 carbonic anhydrase 13 decreases expression ISO Gold results in decreased expression of CA13 mRNA CTD PMID:25523186 NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 decreases expression ISO Gold results in decreased expression of CAPZA2 mRNA CTD PMID:25523186 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of CASP1 mRNA CTD PMID:28433809 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression
ISO
EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP3 mRNA; [Polyethyleneimine binds to Gold] which results in increased expression of CASP3 mRNA; [Quercetin analog co-treated with Gold analog] results in increased cleavage of CASP3 protein; [Quercetin analog co-treated with Gold analog] results in increased expression of and results in increased activity of CASP3 protein; Dexamethasone promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]
[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP3 protein
Gold analog results in increased cleavage of CASP3 protein
Gold results in increased expression of CASP3 mRNA
CTD PMID:19760634 PMID:21621595 PMID:22178767 PMID:25846798 PMID:26551149 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases cleavage ISO Gold analog results in increased cleavage of CASP4 protein CTD PMID:26551149 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 increases cleavage ISO Gold analog results in increased cleavage of CASP7 protein CTD PMID:26551149 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression ISO Gold results in increased expression of CASP8 mRNA CTD PMID:22178767 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO
EXP
[Gold analog co-treated with Platinum] results in increased activity of CASP9 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP9 mRNA
Gold analog results in increased cleavage of CASP9 protein
[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP9 protein
CTD PMID:25846798 PMID:26551149 PMID:27836789 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein] CTD PMID:27836789 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Gold results in decreased expression of CBX3 mRNA CTD PMID:25523186 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CCL2 protein
Gold results in increased secretion of CCL2 protein
CTD PMID:22155353 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CCL5 protein
Gold results in increased secretion of CCL5 protein
CTD PMID:22155353 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CCL7 protein
Gold results in increased secretion of CCL7 protein
CTD PMID:22155353 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased expression of CCND1 protein CTD PMID:27470402 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO Gold analog results in decreased expression of CCT5 protein CTD PMID:24780912 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CD40 mRNA CTD PMID:28433809 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cda cytidine deaminase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of CDA mRNA CTD PMID:19695318 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
increases expression
ISO Gold results in decreased expression of CDK1 mRNA
Gold results in increased expression of CDK1 mRNA
CTD PMID:25523186 PMID:29705079 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CDK7 mRNA CTD PMID:19695318 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Gold binds to Dimethyldithiocarbamate] which results in increased expression of CDKN1B protein CTD PMID:17079469 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2aip CDKN2A interacting protein decreases expression ISO Gold results in decreased expression of CDKN2AIP mRNA CTD PMID:25523186 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 decreases expression ISO Gold results in decreased expression of CGRRF1 mRNA CTD PMID:25523186 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CHEK1 mRNA CTD PMID:28433809 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression ISO Gold results in decreased expression of CHORDC1 mRNA CTD PMID:25523186 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 decreases expression ISO Gold results in decreased expression of CISD1 mRNA CTD PMID:25523186 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Cldn12 claudin 12 decreases expression ISO Gold results in decreased expression of CLDN12 mRNA CTD PMID:25523186 NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO Gold results in decreased expression of CNBP mRNA CTD PMID:25523186 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 decreases expression ISO Gold results in decreased expression of CNOT7 mRNA CTD PMID:25523186 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Gold analog results in increased expression of COL1A1 protein CTD PMID:24780912 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of COL1A2 mRNA CTD PMID:19695318 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of COL3A1 mRNA CTD PMID:19695318 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Commd8 COMM domain containing 8 decreases expression ISO Gold results in decreased expression of COMMD8 mRNA CTD PMID:25523186 NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617
JBrowse link
G Cox11 cytochrome c oxidase copper chaperone COX11 decreases expression ISO Gold results in decreased expression of COX11 mRNA CTD PMID:25523186 NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO Gold results in decreased expression of COX17 mRNA CTD PMID:25523186 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CPT1A mRNA CTD PMID:28433809 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CPT2 mRNA CTD PMID:28433809 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CSF2 protein
Gold results in increased secretion of CSF2 protein
CTD PMID:22155353 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 increases secretion
multiple interactions
ISO Gold results in increased secretion of CSF3 protein
[Gold co-treated with Silicon Dioxide] results in increased secretion of CSF3 protein
CTD PMID:22155353 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Ctcf CCCTC-binding factor multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of CTCF mRNA CTD PMID:19695318 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Cux1 cut-like homeobox 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of CUX1 mRNA CTD PMID:19695318 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion
multiple interactions
ISO Gold results in increased secretion of CXCL10 protein
[Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL10 protein
CTD PMID:22155353 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases secretion
ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL2 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL2 protein
Gold results in increased secretion of CXCL2 protein
CTD PMID:19695318 PMID:22155353 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL1 mRNA CTD PMID:19695318 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of CYCS protein CTD PMID:21621595 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
ISO Gold analog results in increased activity of CYP1A1 protein
[Polyethyleneimine binds to Gold] which results in decreased expression of CYP1A1 mRNA
CTD PMID:20193702 PMID:28433809 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO Gold results in increased expression of CYP24A1 mRNA CTD PMID:29705079 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CYP2D6 mRNA CTD PMID:28433809 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyth1 cytohesin 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CYTH1 mRNA CTD PMID:19695318 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
JBrowse link
G Dcp2 decapping mRNA 2 decreases expression ISO Gold results in decreased expression of DCP2 mRNA CTD PMID:25523186 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Ddc dopa decarboxylase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of DDC mRNA CTD PMID:19695318 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of DDIT3 mRNA CTD PMID:28433809 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of DDIT4 mRNA CTD PMID:19695318 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Defb1 defensin beta 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DEFB1 mRNA CTD PMID:28433809 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of DHCR24 mRNA
[Polyethyleneimine binds to Gold] which results in decreased expression of DHCR24 mRNA
CTD PMID:19695318 PMID:28433809 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dnah14 dynein axonemal heavy chain 14 decreases expression ISO Gold results in decreased expression of DNAH14 mRNA CTD PMID:25523186 NCBI chr13:93,322,653...93,540,706 JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of DNAJA3 mRNA CTD PMID:28433809 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 decreases expression ISO Gold results in decreased expression of DNAJB14 mRNA CTD PMID:25523186 NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 decreases expression ISO Gold results in decreased expression of DNAJB6 mRNA CTD PMID:25523186 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression ISO Gold results in decreased expression of DNAJB9 mRNA CTD PMID:25523186 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 decreases expression ISO Gold results in decreased expression of DNAJC10 mRNA CTD PMID:25523186 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Gold results in decreased expression of DNAJC19 mRNA CTD PMID:25523186 NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
JBrowse link
G Dnajc21 DnaJ heat shock protein family (Hsp40) member C21 decreases expression ISO Gold results in decreased expression of DNAJC21 mRNA CTD PMID:25523186 NCBI chr 2:59,419,505...59,446,743
Ensembl chr 2:59,419,510...59,446,752
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DNAJC5 mRNA CTD PMID:28433809 NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP Gold inhibits the reaction [3-N-methylspiperone binds to DRD3 protein] CTD PMID:10215675 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions EXP Gold inhibits the reaction [3-N-methylspiperone binds to DRD4 protein] CTD PMID:10215675 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dsc2 desmocollin 2 increases expression ISO Gold results in increased expression of DSC2 mRNA CTD PMID:29705079 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Dsg2 desmoglein 2 increases expression ISO Gold results in increased expression of DSG2 mRNA CTD PMID:29705079 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DUOX1 mRNA CTD PMID:28433809 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DUOX2 mRNA CTD PMID:28433809 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of DUSP1 mRNA CTD PMID:19695318 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO Gold results in decreased expression of DUSP11 mRNA CTD PMID:25523186 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression ISO Gold results in decreased expression of DUT mRNA CTD PMID:25523186 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Dzip3 DAZ interacting zinc finger protein 3 decreases expression ISO Gold results in decreased expression of DZIP3 mRNA CTD PMID:25523186 NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of EDEM3 mRNA CTD PMID:28433809 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Eea1 early endosome antigen 1 decreases expression ISO Gold results in decreased expression of EEA1 mRNA CTD PMID:25523186 NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta decreases expression ISO Gold analog results in decreased expression of EEF1D protein CTD PMID:24780912 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression ISO Gold analog results in decreased expression of EEF2 protein CTD PMID:24780912 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]] CTD PMID:27634460 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of EID1 mRNA CTD PMID:19695318 NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked decreases expression ISO Gold results in decreased expression of EIF1AX mRNA CTD PMID:25523186 NCBI chr  X:35,498,698...35,513,402
Ensembl chr  X:35,498,517...35,513,335
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO Gold analog results in increased phosphorylation of EIF2AK3 protein CTD PMID:26551149 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Gold results in decreased expression of EIF4A2 mRNA CTD PMID:25523186 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein CTD PMID:27470402 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein CTD PMID:27470402 NCBI chr18:28,263,089...28,268,033 JBrowse link
G Eif5b eukaryotic translation initiation factor 5B multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of EIF5B mRNA CTD PMID:28433809 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
JBrowse link
G Eno1 enolase 1 multiple interactions ISO Gold analog results in decreased expression of and results in increased phosphorylation of ENO1 protein CTD PMID:24780912 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Polyethyleneimine binds to Gold] which results in decreased expression of EP300 mRNA; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]] CTD PMID:27634460 PMID:28433809 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epgn epithelial mitogen increases expression ISO Gold results in increased expression of EPGN mRNA CTD PMID:29705079 NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of EPHA1 mRNA CTD PMID:19695318 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ERCC2 mRNA CTD PMID:28433809 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Gold analog results in increased phosphorylation of ERN1 protein CTD PMID:26551149 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Gold results in increased expression of ERO1A mRNA CTD PMID:29705079 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Gold results in decreased expression of ESCO2 mRNA CTD PMID:25523186 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Evi5 ecotropic viral integration site 5 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of EVI5 mRNA CTD PMID:19695318 NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
JBrowse link
G Evx1 even-skipped homeobox 1 increases expression ISO Gold results in increased expression of EVX1 mRNA CTD PMID:25523186
G Fancl FA complementation group L decreases expression ISO Gold results in decreased expression of FANCL mRNA CTD PMID:25523186 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of FAS mRNA CTD PMID:28433809 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of FGF1 mRNA CTD PMID:19695318 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of FH mRNA CTD PMID:28433809 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 increases phosphorylation
decreases expression
ISO Gold analog results in increased phosphorylation of FKBP9 protein
Gold analog results in decreased expression of FKBP9 protein
CTD PMID:24780912 NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of FMO5 mRNA CTD PMID:28433809 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Gold co-treated with Silicon Dioxide] results in increased expression of FOS mRNA
Gold results in increased expression of FOS mRNA
CTD PMID:22155353 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Gold results in increased expression of FTH1 mRNA CTD PMID:29705079 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO Gold results in increased expression of FYB mRNA CTD PMID:29705079 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Fzd4 frizzled class receptor 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of FZD4 mRNA CTD PMID:19695318 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase decreases expression ISO Gold results in decreased expression of G2E3 mRNA CTD PMID:25523186 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO Gold results in decreased expression of GALNT1 mRNA CTD PMID:25523186 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of GANC mRNA CTD PMID:19695318 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO Gold analog results in decreased expression of GAPDH protein CTD PMID:24780912 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gca grancalcin decreases expression ISO Gold results in decreased expression of GCA mRNA CTD PMID:25523186 NCBI chr 3:47,297,320...47,328,581
Ensembl chr 3:47,297,383...47,328,581
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of GCDH mRNA CTD PMID:28433809 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
G Gmps guanine monophosphate synthase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of GMPS mRNA CTD PMID:19695318 NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
JBrowse link
G Gng10 G protein subunit gamma 10 decreases expression ISO Gold results in decreased expression of GNG10 mRNA CTD PMID:25523186 NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression ISO Gold analog results in decreased expression of GOT2 protein CTD PMID:24780912 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpr182 G protein-coupled receptor 182 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of GPR182 mRNA CTD PMID:19695318 NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]; [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein]
[Polyethyleneimine binds to Gold] which results in decreased expression of GPT mRNA
CTD PMID:27836789 PMID:28433809 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Gold results in increased expression of GPX2 mRNA CTD PMID:25523186 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsn gelsolin decreases expression
increases degradation
ISO Gold analog results in decreased expression of GSN protein
Gold analog results in increased degradation of GSN protein
CTD PMID:24780912 PMID:26551149 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gstm4 glutathione S-transferase mu 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of GSTM4 mRNA CTD PMID:28433809 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Hat1 histone acetyltransferase 1 decreases expression ISO Gold results in decreased expression of HAT1 mRNA CTD PMID:25523186 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO [Polyethylene Glycols binds to Gold] which results in increased expression of HAVCR1 protein; [Polyethyleneimine binds to Gold] which results in increased expression of HAVCR1 protein; [Thioctic Acid binds to Gold] which results in increased expression of HAVCR1 protein CTD PMID:28433809 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 increases expression ISO Gold results in increased expression of HCAR2 mRNA CTD PMID:29705079 NCBI chr12:32,726,334...32,727,416
Ensembl chr12:32,726,184...32,728,504
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Gold results in decreased expression of HMGB2 mRNA CTD PMID:25523186 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Gold results in increased expression of HMOX1 mRNA CTD PMID:25523186 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression ISO Gold results in decreased expression of HPRT1 mRNA CTD PMID:25523186 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsbp1 heat shock factor binding protein 1 decreases expression ISO Gold results in decreased expression of HSBP1 mRNA CTD PMID:25523186 NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of HSF1 mRNA CTD PMID:28433809 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of HSP90AB1 mRNA CTD PMID:19695318 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 decreases expression ISO Gold results in decreased expression of HSPA13 mRNA CTD PMID:25523186 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1A mRNA CTD PMID:28433809
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1B mRNA CTD PMID:28433809 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPA4 mRNA CTD PMID:19695318 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO Gold analog results in increased expression of HSPA8 protein CTD PMID:24780912 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of HSPA9 mRNA CTD PMID:19695318 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPB1 mRNA
[Polyethyleneimine binds to Gold] which results in decreased expression of HSPB1 mRNA
CTD PMID:19695318 PMID:28433809 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of HSPD1 mRNA CTD PMID:28433809 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Gold results in increased expression of HTATIP2 mRNA CTD PMID:29705079 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 decreases expression ISO Gold results in decreased expression of HTATSF1 mRNA CTD PMID:25523186 NCBI chr  X:134,935,426...134,949,607
Ensembl chr  X:134,935,426...134,949,607
JBrowse link
G Hyou1 hypoxia up-regulated 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of HYOU1 mRNA CTD PMID:19695318 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO Gold analog results in decreased expression of and results in increased phosphorylation of IDH1 protein CTD PMID:24780912 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of IDH3G mRNA CTD PMID:28433809 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Gold results in increased expression of IFNGR1 mRNA CTD PMID:29705079 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Gold inhibits the reaction [IGF1 protein binds to IGF1R protein]; Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions ISO Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Gold results in decreased expression of IKZF2 mRNA CTD PMID:25523186 NCBI chr 9:71,042,440...71,191,296
Ensembl chr 9:71,042,440...71,190,867
JBrowse link
G Il10 interleukin 10 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of IL10 protein
Gold results in increased secretion of IL10 protein
CTD PMID:22155353 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein
Gold results in increased secretion of IL1A protein
CTD PMID:22155353 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of IL1B mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1B protein
Gold results in increased secretion of IL1B protein
CTD PMID:19695318 PMID:22155353 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of IL6 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL6 protein
[Polyethylene Glycols binds to Gold] which results in increased expression of IL6 protein; [Polyethyleneimine binds to Gold] which results in increased expression of IL6 protein; [Thioctic Acid binds to Gold] which results in increased expression of IL6 protein
Gold results in increased secretion of IL6 protein
CTD PMID:19695318 PMID:22155353 PMID:28433809 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of IL6RA mRNA CTD PMID:19695318 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Impa1 inositol monophosphatase 1 decreases expression ISO Gold results in decreased expression of IMPA1 mRNA CTD PMID:25523186 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression ISO Gold results in decreased expression of IPMK mRNA CTD PMID:25523186 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of IQGAP2 mRNA CTD PMID:19695318 NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of JAK2 protein CTD PMID:27470402 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]] CTD PMID:27634460 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jup junction plakoglobin decreases expression ISO Gold analog results in decreased expression of JUP protein CTD PMID:24780912 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Kin Kin17 DNA and RNA binding protein decreases expression ISO Gold results in decreased expression of KIN mRNA CTD PMID:25523186 NCBI chr17:68,413,483...68,431,392
Ensembl chr17:68,413,486...68,423,845
JBrowse link
G Kitlg KIT ligand decreases expression ISO Gold results in decreased expression of KITLG mRNA CTD PMID:25523186 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Krr1 KRR1, small subunit processome component homolog decreases expression ISO Gold results in decreased expression of KRR1 mRNA CTD PMID:25523186 NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
JBrowse link
G Kynu kynureninase increases expression ISO Gold results in increased expression of KYNU mRNA CTD PMID:29705079 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Lacc1 laccase domain containing 1 increases expression ISO Gold results in increased expression of LACC1 mRNA CTD PMID:29705079 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545
JBrowse link
G Lactb2 lactamase, beta 2 decreases expression ISO Gold results in decreased expression of LACTB2 mRNA CTD PMID:25523186 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429
JBrowse link
G Larp1b La ribonucleoprotein 1B decreases expression ISO Gold results in decreased expression of LARP1B mRNA CTD PMID:25523186 NCBI chr 2:123,936,074...123,969,254
Ensembl chr 2:123,935,983...123,968,896
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of LIF protein
Gold results in increased secretion of LIF protein
CTD PMID:22155353 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lig4 DNA ligase 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which affects the expression of LIG4 mRNA CTD PMID:28433809 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Lima1 LIM domain and actin binding 1 decreases expression ISO Gold results in decreased expression of LIMA1 mRNA CTD PMID:25523186 NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Lman1 lectin, mannose-binding, 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of LMAN1 mRNA CTD PMID:19695318 NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
JBrowse link
G Lmna lamin A/C multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of LMNA mRNA CTD PMID:28433809 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lmnb1 lamin B1 increases degradation ISO Gold analog results in increased degradation of LMNB1 protein CTD PMID:26551149 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G LOC108348302 zinc finger protein 709-like decreases expression ISO Gold results in decreased expression of ZNF124 mRNA CTD PMID:25523186 NCBI chr16:19,643,587...19,654,567
Ensembl chr16:19,641,609...19,674,971
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of LPGAT1 mRNA CTD PMID:19695318 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Lratd1 LRAT domain containing 1 increases expression ISO Gold results in increased expression of LRATD1 mRNA CTD PMID:25523186 NCBI chr 6:36,916,969...36,922,143
Ensembl chr 6:36,913,469...36,922,319
JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Gold results in decreased expression of LSM5 mRNA CTD PMID:25523186 NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165
JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Gold results in decreased expression of LSM6 mRNA CTD PMID:25523186 NCBI chr19:29,098,254...29,112,858
Ensembl chr19:29,098,214...29,118,682
JBrowse link
G Lss lanosterol synthase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of LSS mRNA CTD PMID:28433809 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Gold results in decreased expression of MAD2L1 mRNA CTD PMID:25523186 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO Gold results in increased expression of MAP1B mRNA CTD PMID:29705079 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]] CTD PMID:27634460 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 decreases expression ISO Gold results in decreased expression of MBNL2 mRNA CTD PMID:25523186 NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mdh1b malate dehydrogenase 1B multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of MDH1B mRNA CTD PMID:28433809 NCBI chr 9:65,120,370...65,168,008
Ensembl chr 9:65,119,029...65,167,933
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of MECR mRNA CTD PMID:19695318 NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin increases expression ISO Gold results in increased expression of MEFV mRNA CTD PMID:25523186 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
JBrowse link
G Metap2 methionyl aminopeptidase 2 decreases expression ISO Gold results in decreased expression of METAP2 mRNA CTD PMID:25523186 NCBI chr 7:28,412,771...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of MKI67 mRNA CTD PMID:28433809 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmgt1 membrane magnesium transporter 1 decreases expression ISO Gold results in decreased expression of MMGT1 mRNA CTD PMID:25523186 NCBI chr  X:134,408,463...134,420,798
Ensembl chr  X:134,408,466...134,420,729
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Gold results in increased expression of MMP3 mRNA CTD PMID:24022940 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]] CTD PMID:27634460 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase decreases expression ISO Gold results in decreased expression of MNAT1 mRNA CTD PMID:25523186 NCBI chr 6:91,814,703...91,971,945
Ensembl chr 6:91,814,749...91,970,744
JBrowse link
G Mob1b MOB kinase activator 1B decreases expression ISO Gold results in decreased expression of MOB1B mRNA CTD PMID:25523186 NCBI chr14:19,333,058...19,365,845
Ensembl chr14:19,332,459...19,365,845
JBrowse link
G Mob4 MOB family member 4, phocein decreases expression ISO Gold results in decreased expression of MOB4 mRNA CTD PMID:25523186 NCBI chr 9:56,617,374...56,641,336
Ensembl chr 9:56,617,368...56,641,329
JBrowse link
G Morc3 MORC family CW-type zinc finger 3 decreases expression ISO Gold results in decreased expression of MORC3 mRNA CTD PMID:25523186 NCBI chr11:33,151,906...33,194,646
Ensembl chr11:33,152,025...33,194,646
JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 decreases expression ISO Gold results in decreased expression of MRPL3 mRNA CTD PMID:25523186 NCBI chr 8:105,670,184...105,693,544
Ensembl chr 8:105,670,184...105,693,544
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 decreases expression ISO Gold results in decreased expression of MRPS6 mRNA CTD PMID:25523186 NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Gold results in increased expression of MT2A mRNA CTD PMID:25523186 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mthfr methylenetetrahydrofolate reductase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of MTHFR mRNA CTD PMID:19695318 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtmr6 myotubularin related protein 6 decreases expression ISO Gold results in decreased expression of MTMR6 mRNA CTD PMID:25523186 NCBI chr15:34,419,868...34,457,863
Ensembl chr15:34,419,903...34,457,861
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of MTOR protein CTD PMID:27470402 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression ISO Gold results in increased expression of MTSS1 mRNA CTD PMID:29705079 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of MTTP mRNA CTD PMID:28433809 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of MYCL mRNA CTD PMID:19695318 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
JBrowse link
G Mynn myoneurin decreases expression ISO Gold results in decreased expression of MYNN mRNA CTD PMID:25523186 NCBI chr 2:112,779,654...112,797,188
Ensembl chr 2:112,779,657...112,796,397
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D decreases expression ISO Gold results in decreased expression of NAPEPLD mRNA CTD PMID:25523186 NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of NCEH1 mRNA CTD PMID:19695318 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO Gold results in increased activity of NFE2L2 promoter CTD PMID:21643505 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbid NFKB inhibitor delta multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of NFKBID mRNA CTD PMID:19695318 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Nfkbiz NFKB inhibitor zeta multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of NFKBIZ mRNA CTD PMID:19695318 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nipbl NIPBL, cohesin loading factor multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of NIPBL mRNA CTD PMID:19695318 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO Gold results in increased expression of NOS2 protein CTD PMID:24022940 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of NPLOC4 mRNA CTD PMID:28433809 NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913
JBrowse link
G Npm1 nucleophosmin 1 decreases expression ISO Gold results in decreased expression of NPM1 mRNA CTD PMID:25523186 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO [Polyethyleneimine binds to Gold] which results in increased expression of NQO1 mRNA
Gold results in increased expression of NQO1 mRNA
CTD PMID:28433809 PMID:29705079 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of NR4A1 mRNA CTD PMID:19695318 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression ISO Gold results in increased expression of NRCAM mRNA CTD PMID:29705079 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO Gold results in increased expression of NRIP1 mRNA CTD PMID:29705079 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Ntn4 netrin 4 increases expression ISO Gold results in increased expression of NTN4 mRNA CTD PMID:29705079 NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
JBrowse link
G Nucb1 nucleobindin 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of NUCB1 mRNA CTD PMID:28433809 NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
JBrowse link
G Nudt12 nudix hydrolase 12 decreases expression ISO Gold results in decreased expression of NUDT12 mRNA CTD PMID:25523186 NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039
JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of NUP210 mRNA CTD PMID:28433809 NCBI chr 4:123,511,559...123,609,874
Ensembl chr 4:123,511,559...123,609,874
JBrowse link
G Obi1 ORC ubiquitin ligase 1 decreases expression ISO Gold results in decreased expression of OBI1 mRNA CTD PMID:25523186 NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
JBrowse link
G Odr4 odr-4 GPCR localization factor homolog decreases expression ISO Gold results in decreased expression of ODR4 mRNA CTD PMID:25523186 NCBI chr13:62,369,109...62,424,287
Ensembl chr13:62,394,608...62,424,209
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of OGDH mRNA CTD PMID:28433809 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of OGG1 mRNA CTD PMID:28433809 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Orc4 origin recognition complex, subunit 4 decreases expression ISO Gold results in decreased expression of ORC4 mRNA CTD PMID:25523186 NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of OS9 mRNA CTD PMID:28433809 NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 increases expression ISO Gold results in increased expression of OSGIN1 mRNA CTD PMID:25523186 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Gold analog results in decreased expression of P4HB protein CTD PMID:24780912 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Organogold Compounds promotes the reaction [Gold binds to PARP1 protein] CTD PMID:21370912 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcbp1 poly(rC) binding protein 1 decreases expression ISO Gold analog results in decreased expression of PCBP1 protein CTD PMID:24780912 NCBI chr 4:118,972,698...118,974,722
Ensembl chr 4:118,972,661...118,976,500
JBrowse link
G Pcgf5 polycomb group ring finger 5 decreases expression ISO Gold results in decreased expression of PCGF5 mRNA CTD PMID:25523186 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315
JBrowse link
G Pcgf6 polycomb group ring finger 6 decreases expression ISO Gold results in decreased expression of PCGF6 mRNA CTD PMID:25523186 NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
JBrowse link
G Pde4b phosphodiesterase 4B multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of PDE4B mRNA CTD PMID:19695318 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Per3 period circadian regulator 3 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of PER3 mRNA CTD PMID:19695318 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A decreases expression ISO Gold results in decreased expression of PIGA mRNA CTD PMID:25523186 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804
JBrowse link
G Pigf phosphatidylinositol glycan anchor biosynthesis, class F decreases expression ISO Gold results in decreased expression of PIGF mRNA CTD PMID:25523186 NCBI chr 6:7,589,528...7,617,721
Ensembl chr 6:7,589,570...7,639,675
JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K decreases expression ISO Gold results in decreased expression of PIGK mRNA CTD PMID:25523186 NCBI chr 2:241,630,021...241,715,493
Ensembl chr 2:241,630,053...241,716,134
JBrowse link
G Pigy phosphatidylinositol glycan anchor biosynthesis, class Y decreases expression ISO Gold results in decreased expression of PIGY mRNA CTD PMID:25523186 NCBI chr 8:20,689,621...20,691,863
Ensembl chr 8:20,689,502...20,692,585
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of PIK3R1 mRNA CTD PMID:19695318 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pkm pyruvate kinase M1/2 decreases expression ISO Gold analog results in decreased expression of PKM protein CTD PMID:24780912 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pla2g6 phospholipase A2 group VI multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of PLA2G6 mRNA CTD PMID:19695318 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plekhf2 pleckstrin homology and FYVE domain containing 2 decreases expression ISO Gold results in decreased expression of PLEKHF2 mRNA CTD PMID:25523186 NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
JBrowse link
G Plin3 perilipin 3 increases expression ISO Gold analog results in increased expression of PLIN3 protein CTD PMID:24780912 NCBI chr 9:1,111,178...1,123,117 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of PMAIP1 mRNA CTD PMID:19695318 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Polk DNA polymerase kappa decreases expression ISO Gold results in decreased expression of POLK mRNA CTD PMID:25523186 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313
JBrowse link
G Polr2k RNA polymerase II, I and III subunit K decreases expression ISO Gold results in decreased expression of POLR2K mRNA CTD PMID:25523186 NCBI chr 7:67,347,118...67,359,466
Ensembl chr 7:67,356,113...67,357,668
JBrowse link
G Popdc3 popeye domain containing 3 increases expression ISO Gold results in increased expression of POPDC3 mRNA CTD PMID:29705079 NCBI chr20:48,772,382...48,800,364
Ensembl chr20:48,772,462...48,800,593
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of POR mRNA CTD PMID:28433809 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression ISO Gold results in decreased expression of PPP1CB mRNA CTD PMID:25523186 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha decreases expression ISO Gold analog results in decreased expression of PPP2R1A protein CTD PMID:24780912 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of PPP2R5E mRNA CTD PMID:19695318 NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
JBrowse link
G Prdx1 peroxiredoxin 1 decreases expression ISO Gold analog results in decreased expression of PRDX1 protein CTD PMID:24780912 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prrc2a proline-rich coiled-coil 2A multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of PRRC2A mRNA CTD PMID:19695318 NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO Gold analog results in decreased expression of PSAT1 protein CTD PMID:24780912 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 decreases expression ISO Gold results in decreased expression of PSMD14 mRNA CTD PMID:25523186 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
JBrowse link
G Ptbp2 polypyrimidine tract binding protein 2 decreases expression ISO Gold results in decreased expression of PTBP2 mRNA CTD PMID:25523186 NCBI chr 2:207,812,659...207,874,019
Ensembl chr 2:207,812,920...207,873,506
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Gold results in increased expression of PTGR1 mRNA CTD PMID:29705079 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression ISO Gold results in decreased expression of PTGR2 mRNA CTD PMID:25523186 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO [Gold co-treated with Silicon Dioxide] results in increased expression of PTGS2 mRNA
[Polyethyleneimine binds to Gold] which results in decreased expression of PTGS2 mRNA
Gold results in increased expression of PTGS2 mRNA
CTD PMID:22155353 PMID:28433809 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Gold results in decreased expression of PTS mRNA CTD PMID:25523186 NCBI chr 8:50,870,838...50,877,878
Ensembl chr 8:50,870,841...50,877,869
JBrowse link
G Pvr PVR cell adhesion molecule multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of PVR mRNA CTD PMID:28433809 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Rab11a RAB11a, member RAS oncogene family decreases expression ISO Gold results in decreased expression of RAB11A mRNA CTD PMID:25523186 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Rab18 RAB18, member RAS oncogene family decreases expression ISO Gold results in decreased expression of RAB18 mRNA CTD PMID:25523186 NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta decreases expression ISO Gold results in decreased expression of RABGGTB mRNA CTD PMID:25523186 NCBI chr 2:242,844,758...242,850,022
Ensembl chr 2:242,844,762...242,851,050
JBrowse link
G Rad51b RAD51 paralog B multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of RAD51B mRNA CTD PMID:19695318 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
JBrowse link
G Rai14 retinoic acid induced 14 increases expression ISO Gold results in increased expression of RAI14 mRNA CTD PMID:29705079 NCBI chr 2:59,546,284...59,682,687
Ensembl chr 2:59,546,284...59,681,971
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of RB1CC1 mRNA CTD PMID:19695318 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Rbm12 RNA binding motif protein 12 decreases expression ISO Gold results in decreased expression of RBM12 mRNA CTD PMID:25523186 NCBI chr 3:144,587,548...144,629,950
Ensembl chr 3:144,611,623...144,629,915
JBrowse link
G Rbp1 retinol binding protein 1 increases expression ISO Gold results in increased expression of RBP1 mRNA CTD PMID:29705079 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 decreases expression ISO Gold results in decreased expression of RC3H1 mRNA CTD PMID:25523186 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein] CTD PMID:27634460 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rfk riboflavin kinase decreases expression ISO Gold results in decreased expression of RFK mRNA CTD PMID:25523186 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
JBrowse link
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression ISO Gold results in decreased expression of C11ORF54 mRNA CTD PMID:25523186 NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
JBrowse link
G Rhou ras homolog family member U multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of RHOU mRNA CTD PMID:19695318 NCBI chr19:51,641,408...51,651,249 JBrowse link
G Rnf11 ring finger protein 11 decreases expression ISO Gold results in decreased expression of RNF11 mRNA CTD PMID:25523186
G Rnf13 ring finger protein 13 decreases expression ISO Gold results in decreased expression of RNF13 mRNA CTD PMID:25523186 NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801
JBrowse link
G Rnf138 ring finger protein 138 decreases expression ISO Gold results in decreased expression of RNF138 mRNA CTD PMID:25523186 NCBI chr18:12,291,557...12,315,931 JBrowse link
G Rnf149 ring finger protein 149 decreases expression ISO Gold results in decreased expression of RNF149 mRNA CTD PMID:25523186 NCBI chr 9:41,826,825...41,854,381
Ensembl chr 9:41,830,233...41,854,279
JBrowse link
G Rnf2 ring finger protein 2 decreases expression ISO Gold results in decreased expression of RNF2 mRNA CTD PMID:25523186 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
JBrowse link
G Rnft1 ring finger protein, transmembrane 1 decreases expression ISO Gold results in decreased expression of RNFT1 mRNA CTD PMID:25523186 NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Gold results in decreased expression of RO60 mRNA CTD PMID:25523186 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
JBrowse link
G Rp2 RP2 activator of ARL3 GTPase decreases expression ISO Gold results in decreased expression of RP2 mRNA CTD PMID:25523186 NCBI chr  X:1,872,581...1,916,704
Ensembl chr  X:1,873,306...1,916,688
JBrowse link
G Rps27l ribosomal protein S27-like decreases expression ISO Gold results in decreased expression of RPS27L mRNA CTD PMID:25523186 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein CTD PMID:27470402 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rtn4 reticulon 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of RTN4 mRNA CTD PMID:19695318 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B decreases expression ISO Gold results in decreased expression of SAR1B mRNA CTD PMID:25523186 NCBI chr10:36,024,443...36,054,067
Ensembl chr10:36,024,382...36,054,066
JBrowse link
G Sarnp SAP domain containing ribonucleoprotein decreases expression ISO Gold results in decreased expression of SARNP mRNA CTD PMID:25523186 NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332
JBrowse link
G Scoc short coiled-coil protein decreases expression ISO Gold results in decreased expression of SCOC mRNA CTD PMID:25523186 NCBI chr19:24,659,651...24,689,236
Ensembl chr19:24,659,651...24,693,217
JBrowse link
G Scp2 sterol carrier protein 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of SCP2 mRNA CTD PMID:19695318 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component decreases expression ISO Gold results in decreased expression of SEC23A mRNA CTD PMID:25523186 NCBI chr 6:76,658,793...76,706,125
Ensembl chr 6:76,658,427...76,706,035
JBrowse link
G Sec24a SEC24 homolog A, COPII coat complex component decreases expression ISO Gold results in decreased expression of SEC24A mRNA CTD PMID:25523186 NCBI chr10:35,946,901...36,024,353
Ensembl chr10:35,947,031...36,024,353
JBrowse link
G Sel1l3 SEL1L family member 3 increases expression ISO Gold results in increased expression of SEL1L3 mRNA CTD PMID:29705079 NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
JBrowse link
G Selenot selenoprotein T decreases expression ISO Gold results in decreased expression of SELENOT mRNA CTD PMID:25523186 NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427
JBrowse link
G Septin8 septin 8 decreases expression ISO Gold analog results in decreased expression of SEPTIN8 protein CTD PMID:24780912 NCBI chr10:37,684,639...37,713,704
Ensembl chr10:37,684,639...37,713,174
JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of SERP1 mRNA CTD PMID:28433809 NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116
JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Gold results in increased expression of SERPINE1 mRNA CTD PMID:29705079 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinh1 serpin family H member 1 decreases expression ISO Gold analog results in decreased expression of SERPINH1 protein CTD PMID:24780912 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression ISO Gold results in increased expression of SH3KBP1 mRNA CTD PMID:29705079 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747
JBrowse link
G Slc25a24 solute carrier family 25 member 24 decreases expression ISO Gold analog results in decreased expression of SLC25A24 protein CTD PMID:24780912 NCBI chr 2:196,761,076...196,799,236
Ensembl chr 2:196,761,274...196,799,231
JBrowse link
G Slirp SRA stem-loop interacting RNA binding protein decreases expression ISO Gold results in decreased expression of C14ORF156 mRNA CTD PMID:25523186 NCBI chr 6:107,088,760...107,097,791
Ensembl chr 6:107,088,403...107,097,791
JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` decreases expression ISO Gold results in decreased expression of SMARCAD1 mRNA CTD PMID:25523186 NCBI chr 4:94,311,441...94,379,184
Ensembl chr 4:94,311,489...94,372,563
JBrowse link
G Smc4 structural maintenance of chromosomes 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC4 mRNA CTD PMID:19695318 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Smc6 structural maintenance of chromosomes 6 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC6 mRNA CTD PMID:19695318 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746
JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 decreases expression ISO Gold results in decreased expression of SNRPB2 mRNA CTD PMID:25523186 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
JBrowse link
G Snx6 sorting nexin 6 decreases expression ISO Gold results in decreased expression of SNX6 mRNA CTD PMID:25523186 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of SOD1 mRNA CTD PMID:19695318 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sp100 SP100 nuclear antigen decreases expression ISO Gold results in decreased expression of SP100 mRNA CTD PMID:25523186 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034
JBrowse link
G Sp3 Sp3 transcription factor decreases expression ISO Gold results in decreased expression of SP3 mRNA CTD PMID:25523186 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Spast spastin decreases expression ISO Gold results in decreased expression of SPAST mRNA CTD PMID:25523186 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
JBrowse link
G Spata2 spermatogenesis associated 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of SPATA2 mRNA CTD PMID:28433809 NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of SREBF1 mRNA CTD PMID:28433809 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srek1ip1 SREK1-interacting protein 1 decreases expression ISO Gold results in decreased expression of SREK1IP1 mRNA CTD PMID:25523186 NCBI chr 2:35,976,045...35,999,630 JBrowse link
G Srp9 signal recognition particle 9 decreases expression ISO Gold results in decreased expression of SRP9 mRNA CTD PMID:25523186 NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720
JBrowse link
G Srsf10 serine and arginine rich splicing factor 10 decreases expression ISO Gold results in decreased expression of SRSF10 mRNA CTD PMID:25523186 NCBI chr 5:148,088,765...148,102,964
Ensembl chr 5:148,088,823...148,101,768
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression ISO Gold results in decreased expression of SRSF3 mRNA CTD PMID:25523186 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 decreases expression ISO Gold results in decreased expression of SRSF7 mRNA CTD PMID:25523186 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
increases expression
ISO [Gold co-treated with Silicon Dioxide] results in increased expression of STAT1 mRNA
Gold results in increased expression of STAT1 mRNA
CTD PMID:22155353 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
multiple interactions
ISO Gold results in increased expression of STAT3 mRNA
[Gold co-treated with Silicon Dioxide] results in increased expression of STAT3 mRNA
CTD PMID:22155353 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stau2 staufen double-stranded RNA binding protein 2 decreases expression ISO Gold results in decreased expression of STAU2 mRNA CTD PMID:25523186 NCBI chr 5:2,840,801...3,084,451 JBrowse link
G Stbd1 starch binding domain 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of STBD1 mRNA CTD PMID:28433809 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
JBrowse link
G Steap1 STEAP family member 1 decreases expression ISO Gold results in decreased expression of STEAP1 mRNA CTD PMID:25523186 NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
JBrowse link
G Stk26 serine/threonine kinase 26 decreases expression ISO Gold results in decreased expression of STK26 mRNA CTD PMID:25523186 NCBI chr  X:130,310,855...130,375,677
Ensembl chr  X:130,310,885...130,374,291
JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta decreases expression ISO Gold results in decreased expression of SUCLA2 mRNA CTD PMID:25523186 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
JBrowse link
G Syvn1 synoviolin 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of SYVN1 mRNA CTD PMID:28433809 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 increases expression ISO Gold results in increased expression of TACSTD2 mRNA CTD PMID:29705079 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
G Tada1 transcriptional adaptor 1 decreases expression ISO Gold results in decreased expression of TADA1 mRNA CTD PMID:25523186 NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b decreases expression ISO Gold results in decreased expression of TAF9B mRNA CTD PMID:25523186 NCBI chr  X:71,289,290...71,300,142
Ensembl chr  X:71,289,290...71,300,604
JBrowse link
G Tbl1xr1 TBL1X receptor 1 decreases expression ISO Gold results in decreased expression of TBL1XR1 mRNA CTD PMID:25523186 NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055
JBrowse link
G Tcea1 transcription elongation factor A1 decreases expression ISO Gold results in decreased expression of TCEA1 mRNA CTD PMID:25523186 NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases expression ISO Gold results in decreased expression of TDO2 mRNA CTD PMID:25523186 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
G Tex30 testis expressed 30 decreases expression ISO Gold results in decreased expression of TEX30 mRNA CTD PMID:25523186 NCBI chr 9:46,242,748...46,252,273
Ensembl chr 9:46,242,748...46,252,249
JBrowse link
G Tfec transcription factor EC decreases expression ISO Gold results in decreased expression of TFEC mRNA CTD PMID:25523186 NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Gold results in increased expression of TFPI2 mRNA CTD PMID:29705079 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of TGFB1 mRNA CTD PMID:28433809 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thap1 THAP domain containing 1 decreases expression ISO Gold results in decreased expression of THAP1 mRNA CTD PMID:25523186 NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942
JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein decreases expression ISO Gold results in decreased expression of TIA1 mRNA CTD PMID:25523186 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586
JBrowse link
G Tkt transketolase decreases expression ISO Gold analog results in decreased expression of TKT protein CTD PMID:24780912 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tlk1 tousled-like kinase 1 increases expression ISO Gold results in increased expression of TLK1 mRNA CTD PMID:29705079 NCBI chr 3:55,520,559...55,627,580
Ensembl chr 3:55,503,358...55,691,968
JBrowse link
G Tlr2 toll-like receptor 2 increases expression
multiple interactions
ISO Gold results in increased expression of TLR2 mRNA
Gold promotes the reaction [SAA1 protein binds to TLR2 protein]
CTD PMID:29705079 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO Gold results in increased expression of TM4SF1 mRNA CTD PMID:29705079 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of TMED10 mRNA CTD PMID:19695318 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
ISO Gold results in increased secretion of TNF protein
[Gold co-treated with Silicon Dioxide] results in increased secretion of TNF protein
CTD PMID:22155353 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of TNFAIP3 mRNA CTD PMID:19695318 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfaip8l1 TNF alpha induced protein 8 like 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of TNFAIP8L1 mRNA CTD PMID:28433809 NCBI chr 9:988,587...999,342 JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of TNFRSF10A mRNA CTD PMID:28433809 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of TNFRSF1A mRNA CTD PMID:28433809 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Gold analog results in increased expression of TRP53 mRNA CTD PMID:22486372 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO Gold analog results in decreased expression of TPT1 protein CTD PMID:24780912 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
JBrowse link
G Trim23 tripartite motif-containing 23 decreases expression ISO Gold results in decreased expression of TRIM23 mRNA CTD PMID:25523186 NCBI chr 2:35,302,405...35,335,746
Ensembl chr 2:35,302,409...35,335,743
JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog decreases expression ISO Gold results in decreased expression of TRMT13 mRNA CTD PMID:25523186 NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843
JBrowse link
G Trub1 TruB pseudouridine synthase family member 1 decreases expression ISO Gold results in decreased expression of TRUB1 mRNA CTD PMID:25523186 NCBI chr 1:256,513,418...256,554,549
Ensembl chr 1:256,515,562...256,552,814
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO Gold analog results in decreased expression of TUBA1A protein CTD PMID:24780912 NCBI chr 7:130,113,214...130,116,880 JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Gold analog results in decreased expression of TUBB5 protein CTD PMID:24780912 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial multiple interactions ISO Gold analog results in decreased expression of and results in increased phosphorylation of TUFM protein CTD PMID:24780912 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
JBrowse link
G Txndc5 thioredoxin domain containing 5 multiple interactions ISO Gold analog results in decreased expression of and results in increased phosphorylation of TXNDC5 protein CTD PMID:24780912 NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity
increases expression
EXP
ISO
Gold results in decreased activity of TXNRD1 protein
Gold results in increased expression of TXNRD1 mRNA
CTD PMID:16510263 PMID:20851179 PMID:29705079 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of TXNRD2 mRNA CTD PMID:28433809 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Uap1l1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 decreases expression ISO Gold analog results in decreased expression of UAP1L1 protein CTD PMID:24780912 NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 decreases expression ISO Gold results in decreased expression of UBA2 mRNA CTD PMID:25523186 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682
JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H increases expression ISO Gold results in increased expression of UBE2H mRNA CTD PMID:29705079 NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression ISO Gold results in decreased expression of UBE2N mRNA CTD PMID:25523186 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W decreases expression ISO Gold results in decreased expression of UBE2W mRNA CTD PMID:25523186 NCBI chr 5:2,690,742...2,754,491 JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of UCP2 mRNA CTD PMID:28433809 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 increases expression
decreases expression
ISO Gold results in increased expression of UIMC1 mRNA
Gold results in decreased expression of UIMC1 mRNA
CTD PMID:29705079 NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799
JBrowse link
G Upp2 uridine phosphorylase 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of UPP2 mRNA CTD PMID:19695318 NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
JBrowse link
G Usp1 ubiquitin specific peptidase 1 decreases expression ISO Gold results in decreased expression of USP1 mRNA CTD PMID:25523186 NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
JBrowse link
G Usp15 ubiquitin specific peptidase 15 decreases expression ISO Gold results in decreased expression of USP15 mRNA CTD PMID:25523186 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
JBrowse link
G Usp16 ubiquitin specific peptidase 16 decreases expression ISO Gold results in decreased expression of USP16 mRNA CTD PMID:25523186 NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539
JBrowse link
G Usp33 ubiquitin specific peptidase 33 decreases expression ISO Gold results in decreased expression of USP33 mRNA CTD PMID:25523186 NCBI chr 2:241,283,209...241,328,479
Ensembl chr 2:241,292,985...241,328,479
JBrowse link
G Usp5 ubiquitin specific peptidase 5 decreases expression ISO Gold analog results in decreased expression of USP5 protein CTD PMID:24780912 NCBI chr 4:157,619,643...157,634,711
Ensembl chr 4:157,619,643...157,634,711
JBrowse link
G Vcl vinculin decreases expression ISO Gold analog results in decreased expression of VCL protein CTD PMID:24780912 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Vim vimentin increases degradation ISO Gold analog results in increased degradation of VIM protein CTD PMID:26551149 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wbp4 WW domain binding protein 4 decreases expression ISO Gold results in decreased expression of WBP4 mRNA CTD PMID:25523186 NCBI chr15:54,862,700...54,890,668
Ensembl chr15:54,862,843...54,890,647
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of WEE1 mRNA CTD PMID:19695318 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of XPA mRNA CTD PMID:28433809 NCBI chr 5:60,431,673...60,476,438
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
G Yod1 YOD1 deubiquitinase decreases expression ISO Gold results in decreased expression of YOD1 mRNA CTD PMID:25523186 NCBI chr13:42,175,313...42,177,030
Ensembl chr13:42,174,820...42,177,205
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of YWHAG mRNA CTD PMID:19695318 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Zbtb21 zinc finger and BTB domain containing 21 decreases expression ISO Gold results in decreased expression of ZBTB21 mRNA CTD PMID:25523186 NCBI chr11:37,311,860...37,327,040
Ensembl chr11:37,312,378...37,326,996
JBrowse link
G Zbtb41 zinc finger and BTB domain containing 41 decreases expression ISO Gold results in decreased expression of ZBTB41 mRNA CTD PMID:25523186 NCBI chr13:51,042,948...51,065,768
Ensembl chr13:51,042,948...51,065,768
JBrowse link
G Zc3h15 zinc finger CCCH-type containing 15 decreases expression ISO Gold results in decreased expression of ZC3H15 mRNA CTD PMID:25523186 NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333
JBrowse link
G Zcchc10 zinc finger CCHC-type containing 10 decreases expression ISO Gold results in decreased expression of ZCCHC10 mRNA CTD PMID:25523186 NCBI chr10:37,470,628...37,481,027 JBrowse link
G Zcchc9 zinc finger CCHC-type containing 9 decreases expression ISO Gold results in decreased expression of ZCCHC9 mRNA CTD PMID:25523186 NCBI chr 2:23,038,156...23,048,249
Ensembl chr 2:23,038,317...23,048,217
JBrowse link
G Zcrb1 zinc finger CCHC-type and RNA binding motif containing 1 decreases expression ISO Gold results in decreased expression of ZCRB1 mRNA CTD PMID:25523186 NCBI chr 7:124,525,227...124,538,564
Ensembl chr 7:124,524,870...124,571,261
JBrowse link
G Zdhhc17 zinc finger DHHC-type palmitoyltransferase 17 decreases expression ISO Gold results in decreased expression of ZDHHC17 mRNA CTD PMID:25523186 NCBI chr 7:46,369,963...46,433,691
Ensembl chr 7:46,369,988...46,433,764
JBrowse link
G Zdhhc20 zinc finger DHHC-type palmitoyltransferase 20 decreases expression ISO Gold results in decreased expression of ZDHHC20 mRNA CTD PMID:25523186 NCBI chr15:31,980,057...32,039,006
Ensembl chr15:31,983,155...32,038,989
JBrowse link
G Zfand1 zinc finger AN1-type containing 1 decreases expression ISO Gold results in decreased expression of ZFAND1 mRNA CTD PMID:25523186 NCBI chr 2:91,444,431...91,457,518
Ensembl chr 2:91,444,508...91,453,246
JBrowse link
G Zfand6 zinc finger AN1-type containing 6 decreases expression ISO Gold results in decreased expression of ZFAND6 mRNA CTD PMID:25523186 NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
JBrowse link
G Zfp277 zinc finger protein 277 decreases expression ISO Gold results in decreased expression of ZNF277 mRNA CTD PMID:25523186 NCBI chr 6:57,383,944...57,512,785
Ensembl chr 6:57,383,951...57,512,765
JBrowse link
G Zfp422 zinc finger protein 422 decreases expression ISO Gold results in decreased expression of ZNF22 mRNA CTD PMID:25523186 NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257
JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 decreases expression ISO Gold results in decreased expression of ZFYVE16 mRNA CTD PMID:25523186 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 decreases expression ISO Gold results in decreased expression of ZMPSTE24 mRNA CTD PMID:25523186 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110
JBrowse link
G Zranb2 zinc finger RANBP2-type containing 2 decreases expression ISO Gold results in decreased expression of ZRANB2 mRNA CTD PMID:25523186 NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942
JBrowse link
G Zup1 zinc finger containing ubiquitin peptidase 1 decreases expression ISO Gold results in decreased expression of ZUP1 mRNA CTD PMID:25523186 NCBI chr20:30,785,226...30,815,377
Ensembl chr20:30,785,227...30,815,306
JBrowse link
auranofin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Auranofin analog binds to ALB protein CTD PMID:16791640 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases response to substance
ISO [BAX co-treated with BAK1] results in increased susceptibility to Auranofin; BAK1 mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
BAK1 results in increased susceptibility to Auranofin
CTD PMID:18789312 PMID:21172426 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases response to substance
ISO [BAX co-treated with BAK1] results in increased susceptibility to Auranofin; BAX mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
BAX results in increased susceptibility to Auranofin
CTD PMID:18789312 PMID:21172426 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO BCL2 protein inhibits the reaction [Auranofin results in increased activity of CASP3 protein] CTD PMID:18789312 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
Auranofin promotes the reaction [TNF protein results in increased activity of CASP3 protein]; Auranofin results in decreased expression of and results in increased cleavage of CASP3 protein; BCL2 protein inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
BAK1 mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]; BAX mutant form inhibits the reaction [Auranofin results in increased activity of CASP3 protein]
CTD PMID:15159275 PMID:15191400 PMID:18789312 PMID:20542334 PMID:21699084 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Auranofin results in decreased expression of and results in increased cleavage of CASP8 protein CTD PMID:20542334 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Auranofin results in decreased expression of and results in increased cleavage of CASP9 protein CTD PMID:20542334 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Auranofin results in increased expression of CDKN1A protein CTD PMID:20542334 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions ISO [Auranofin co-treated with Tretinoin] results in increased expression of CEBPE protein CTD PMID:15159275 NCBI chr15:28,169,885...28,171,283
Ensembl chr15:28,169,704...28,171,814
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; Auranofin inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein]
Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein]
CTD PMID:10820281 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO [Peptidoglycan co-treated with Lipopolysaccharides] promotes the reaction [Auranofin results in increased expression of GPX1 protein]; Auranofin promotes the reaction [[Lipopolysaccharides co-treated with Peptidoglycan] results in increased expression of GPX1 protein] CTD PMID:21355852 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Auranofin results in increased expression of HMOX1 mRNA
Auranofin results in increased expression of HMOX1 mRNA; Auranofin results in increased expression of HMOX1 protein
CTD PMID:22008538 PMID:23942037 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Auranofin inhibits the reaction [IL1B protein affects the localization of RELA protein]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:10594346 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of IL6ST protein; [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein; [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein CTD PMID:20542334 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of IL6ST protein CTD PMID:20542334 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Auranofin inhibits the reaction [lipopolysaccharide A results in increased degradation of IRAK1 protein] CTD PMID:17034761 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO Auranofin inhibits the reaction [lipopolysaccharide A results in increased activity of IRF3 protein]; Auranofin inhibits the reaction [lipopolysaccharide A results in increased phosphorylation of IRF3 protein]; Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein]; Auranofin inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [Auranofin co-treated with Tretinoin] results in increased expression of ITGAM protein CTD PMID:15159275 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [Auranofin co-treated with IL6 protein] results in decreased phosphorylation of JAK2 protein CTD PMID:20542334 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
decreases expression
ISO [Auranofin co-treated with SN50 peptide] results in decreased expression of MCL1 protein
Auranofin results in decreased expression of MCL1 protein
CTD PMID:20542334 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Auranofin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:10820281 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Auranofin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:10820281 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
increases cleavage
ISO Auranofin results in decreased activity of PARP1 protein
Auranofin results in increased cleavage of PARP1 protein
CTD PMID:15159275 PMID:21370912 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ppif peptidylprolyl isomerase F increases oxidation
multiple interactions
ISO
EXP
Auranofin results in increased oxidation of PPIF protein
Auranofin inhibits the reaction [[NADP co-treated with TXNRD1 protein] results in increased activity of PPIF protein]; Cyclosporine promotes the reaction [Auranofin results in increased oxidation of PPIF protein]
CTD PMID:26975474 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Prdx3 peroxiredoxin 3 increases oxidation
multiple interactions
ISO
EXP
Auranofin results in increased oxidation of PRDX3 protein
Cyclosporine promotes the reaction [Auranofin results in increased oxidation of PRDX3 protein]
Auranofin promotes the reaction [[Lipopolysaccharides co-treated with Peptidoglycan] results in increased expression of PRDX3 protein]
CTD PMID:18789312 PMID:21355852 PMID:26975474 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [lipopolysaccharide A co-treated with Auranofin] results in decreased expression of PTGS2 protein
Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Auranofin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
CTD PMID:10594346 PMID:17034761 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Auranofin results in decreased phosphorylation of RB1 protein CTD PMID:20542334 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Auranofin inhibits the reaction [IL1B protein affects the localization of RELA protein] CTD PMID:10594346 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RT1-Ba RT1 class II, locus Ba increases response to substance ISO HLA-DQA1 gene polymorphism results in increased susceptibility to Auranofin CTD PMID:11436868 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases response to substance ISO HLA-DRB1 gene polymorphism results in increased susceptibility to Auranofin CTD PMID:11436868 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Auranofin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
multiple interactions
ISO Auranofin results in decreased expression of STAT3 protein modified form
[Auranofin co-treated with IL6 protein] results in decreased phosphorylation of STAT3 protein
CTD PMID:20542334 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO Auranofin inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 multiple interactions ISO Auranofin inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein] CTD PMID:17034761 NCBI chr 9:1,102,559...1,115,573 JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Auranofin inhibits the reaction [lipopolysaccharide A promotes the reaction [TLR4 protein binds to TLR4 protein]] CTD PMID:17034761 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Auranofin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Auranofin promotes the reaction [TNF protein results in increased activity of CASP3 protein]
Auranofin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
CTD PMID:10820281 PMID:18789312 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txn1 thioredoxin 1 increases oxidation ISO Auranofin results in increased oxidation of TXN protein CTD PMID:26975474 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txn2 thioredoxin 2 increases oxidation
multiple interactions
ISO
EXP
Auranofin results in increased oxidation of TXN2 protein
Cyclosporine promotes the reaction [Auranofin results in increased oxidation of TXN2 protein]
CTD PMID:26975474 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity
increases oxidation
increases expression
ISO
EXP
Auranofin inhibits the reaction [Sodium Selenite results in increased activity of TXNRD1 protein]; Auranofin promotes the reaction [Sodium Selenite results in increased expression of TXNRD1 mRNA]; potassium tellurate(IV) promotes the reaction [Auranofin results in increased oxidation of TXNRD1 protein]; Sodium Selenite promotes the reaction [Auranofin results in increased oxidation of TXNRD1 protein]
Auranofin inhibits the reaction [[NADP co-treated with TXNRD1 protein] results in increased activity of PPIF protein]; Auranofin inhibits the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides]
Auranofin results in decreased activity of TXNRD1 protein
Auranofin results in increased expression of TXNRD1 mRNA
CTD PMID:16510263 PMID:18405881 PMID:18789312 PMID:19486940 PMID:20457604 More... NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions
decreases activity
ISO
EXP
Auranofin inhibits the reaction [Sodium Selenite results in increased activity of TXNRD2 protein]; Auranofin promotes the reaction [Sodium Selenite results in decreased expression of TXNRD2 mRNA]
Auranofin results in decreased activity of TXNRD2 protein
CTD PMID:15458826 PMID:19486940 PMID:21172426 PMID:21355852 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
gold nanoparticle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor decreases secretion EXP Topical GNP decreases secretion of Tnf protein in aqeous humor RGD PMID:23150627 RGD:7815044 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
gold(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of AASS mRNA CTD PMID:28433809 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA CTD PMID:28433809 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ABCC1 mRNA CTD PMID:28433809 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ABL1 mRNA CTD PMID:28433809 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ACADS mRNA CTD PMID:28433809 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ACADVL mRNA CTD PMID:28433809 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Aco1 aconitase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of ACO1 mRNA CTD PMID:28433809 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 decreases expression
multiple interactions
ISO Gold analog results in decreased expression of ACO2 protein
[Polyethyleneimine binds to Gold] which results in increased expression of ACO2 mRNA
CTD PMID:24780912 PMID:28433809 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ACOX1 mRNA CTD PMID:19695318 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acp1 acid phosphatase 1 decreases expression ISO Gold results in decreased expression of ACP1 mRNA CTD PMID:25523186 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
JBrowse link
G Acvr1c activin A receptor type 1C decreases expression ISO Gold results in decreased expression of ACVR1C mRNA CTD PMID:25523186 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 increases expression ISO Gold results in increased expression of ADAM28 mRNA CTD PMID:29705079 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide decreases expression ISO Gold results in decreased expression of ADH5 mRNA CTD PMID:25523186 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ADIPOR2 mRNA CTD PMID:19695318 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of ADRA1B mRNA CTD PMID:19695318 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of ADRB2 mRNA CTD PMID:19695318 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Gold results in increased expression of AIFM1 protein CTD PMID:25462594 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 decreases expression ISO Gold results in decreased expression of AIMP1 mRNA CTD PMID:25523186 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Gold results in decreased expression of AK3 mRNA CTD PMID:25523186 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Akap13 A-kinase anchoring protein 13 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of AKAP13 mRNA CTD PMID:19695318 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Gold results in increased expression of AKR1B10 mRNA CTD PMID:29705079 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Gold results in increased expression of AKR1C2 mRNA CTD PMID:29705079 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Gold results in increased expression of AKR1C3 mRNA CTD PMID:29705079 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of AKT1 protein CTD PMID:27470402 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions ISO ALB protein results in increased uptake of [Polyethylene Glycols binds to Gold]; ALB protein results in increased uptake of [Polyethyleneimine binds to Gold]; ALB protein results in increased uptake of [Thioctic Acid binds to Gold] CTD PMID:28433809 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Anxa5 annexin A5 increases expression ISO Gold analog results in increased expression of ANXA5 protein CTD PMID:24780912 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 protein CTD PMID:27470402 PMID:28433809 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of APOA4 mRNA CTD PMID:19695318 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO Gold analog results in decreased expression of APRT protein CTD PMID:24780912 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Aqp4 aquaporin 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of AQP4 mRNA CTD PMID:28433809 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 decreases expression ISO Gold results in decreased expression of ARL1 mRNA CTD PMID:25523186 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B decreases expression ISO Gold results in decreased expression of ARL5B mRNA CTD PMID:25523186 NCBI chr17:77,955,749...77,983,745
Ensembl chr17:77,955,818...77,979,854
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ARNTL mRNA CTD PMID:19695318 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arsg arylsulfatase G multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ARSG mRNA CTD PMID:19695318 NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
JBrowse link
G Atf1 activating transcription factor 1 decreases expression ISO Gold results in decreased expression of ATF1 mRNA CTD PMID:25523186 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ATF4 mRNA CTD PMID:28433809 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 increases cleavage ISO Gold analog results in increased cleavage of ATF6 protein CTD PMID:26551149 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase decreases expression ISO Gold analog results in decreased expression of ATIC protein CTD PMID:24780912 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atl2 atlastin GTPase 2 decreases expression ISO Gold results in decreased expression of ATL2 mRNA CTD PMID:25523186 NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of ATP2B1 mRNA CTD PMID:19695318 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta multiple interactions ISO Gold analog results in increased expression of and results in decreased phosphorylation of ATP5B protein CTD PMID:24780912 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of BACE1 mRNA CTD PMID:19695318 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in increased expression of BAD protein CTD PMID:27470402 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of BAIAP2 mRNA CTD PMID:19695318 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Gold results in increased expression of BAK1 mRNA CTD PMID:22178767 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of BAX protein; [Gold analog co-treated with Platinum] results in increased expression of BAX mRNA; [Polyethyleneimine binds to Gold] which results in decreased expression of BAX mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of BAX protein
[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of BAX protein
Gold results in increased expression of BAX mRNA
CTD PMID:21621595 PMID:22178767 PMID:25846798 PMID:27470402 PMID:27836789 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor decreases expression ISO Gold results in decreased expression of BCAS2 mRNA CTD PMID:25523186 NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP
[Gold analog co-treated with Platinum] results in decreased expression of BCL2 mRNA; [Quercetin analog co-treated with Gold analog] results in decreased expression of BCL2 protein
[Gold binds to NKCT1 protein, Naja kaouthia] which results in decreased expression of BCL2 protein
CTD PMID:25846798 PMID:27470402 PMID:27836789 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of BCL2L1 mRNA CTD PMID:28433809 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Gold results in decreased expression of BIRC2 mRNA CTD PMID:25523186 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Gold results in decreased expression of BIRC3 mRNA CTD PMID:25523186 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger decreases expression ISO Gold results in decreased expression of BMI1 mRNA CTD PMID:25523186 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of BRCA1 mRNA CTD PMID:28433809 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of BRCA2 mRNA CTD PMID:28433809 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Bves blood vessel epicardial substance increases expression ISO Gold results in increased expression of BVES mRNA CTD PMID:29705079 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
JBrowse link
G C1d C1D nuclear receptor corepressor decreases expression ISO Gold results in decreased expression of C1D mRNA CTD PMID:25523186 NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852
JBrowse link
G C3 complement C3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of C3 mRNA CTD PMID:28433809 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Ca13 carbonic anhydrase 13 decreases expression ISO Gold results in decreased expression of CA13 mRNA CTD PMID:25523186 NCBI chr 2:86,928,401...86,959,525
Ensembl chr 2:86,928,383...86,959,525
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 decreases expression ISO Gold results in decreased expression of CAPZA2 mRNA CTD PMID:25523186 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of CASP1 mRNA CTD PMID:28433809 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression
ISO
EXP
[[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased activity of CASP3 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP3 mRNA; [Polyethyleneimine binds to Gold] which results in increased expression of CASP3 mRNA; [Quercetin analog co-treated with Gold analog] results in increased cleavage of CASP3 protein; [Quercetin analog co-treated with Gold analog] results in increased expression of and results in increased activity of CASP3 protein; Dexamethasone promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]
[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP3 protein
Gold analog results in increased cleavage of CASP3 protein
Gold results in increased expression of CASP3 mRNA
CTD PMID:19760634 PMID:21621595 PMID:22178767 PMID:25846798 PMID:26551149 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases cleavage ISO Gold analog results in increased cleavage of CASP4 protein CTD PMID:26551149 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 increases cleavage ISO Gold analog results in increased cleavage of CASP7 protein CTD PMID:26551149 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression ISO Gold results in increased expression of CASP8 mRNA CTD PMID:22178767 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO
EXP
[Gold analog co-treated with Platinum] results in increased activity of CASP9 protein; [Gold analog co-treated with Platinum] results in increased expression of CASP9 mRNA
[Gold binds to NKCT1 protein, Naja kaouthia] which results in increased expression of CASP9 protein
Gold analog results in increased cleavage of CASP9 protein
CTD PMID:25846798 PMID:26551149 PMID:27836789 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein] CTD PMID:27836789 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Gold results in decreased expression of CBX3 mRNA CTD PMID:25523186 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CCL2 protein
Gold results in increased secretion of CCL2 protein
CTD PMID:22155353 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CCL5 protein
Gold results in increased secretion of CCL5 protein
CTD PMID:22155353 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CCL7 protein
Gold results in increased secretion of CCL7 protein
CTD PMID:22155353 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased expression of CCND1 protein CTD PMID:27470402 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO Gold analog results in decreased expression of CCT5 protein CTD PMID:24780912 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CD40 mRNA CTD PMID:28433809 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cda cytidine deaminase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of CDA mRNA CTD PMID:19695318 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
increases expression
ISO Gold results in decreased expression of CDK1 mRNA
Gold results in increased expression of CDK1 mRNA
CTD PMID:25523186 PMID:29705079 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CDK7 mRNA CTD PMID:19695318 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Gold binds to Dimethyldithiocarbamate] which results in increased expression of CDKN1B protein CTD PMID:17079469 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2aip CDKN2A interacting protein decreases expression ISO Gold results in decreased expression of CDKN2AIP mRNA CTD PMID:25523186 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 decreases expression ISO Gold results in decreased expression of CGRRF1 mRNA CTD PMID:25523186 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CHEK1 mRNA CTD PMID:28433809 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 decreases expression ISO Gold results in decreased expression of CHORDC1 mRNA CTD PMID:25523186 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 decreases expression ISO Gold results in decreased expression of CISD1 mRNA CTD PMID:25523186 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Cldn12 claudin 12 decreases expression ISO Gold results in decreased expression of CLDN12 mRNA CTD PMID:25523186 NCBI chr 4:28,522,659...28,533,647
Ensembl chr 4:28,522,678...28,533,801
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO Gold results in decreased expression of CNBP mRNA CTD PMID:25523186 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 decreases expression ISO Gold results in decreased expression of CNOT7 mRNA CTD PMID:25523186 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Gold analog results in increased expression of COL1A1 protein CTD PMID:24780912 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of COL1A2 mRNA CTD PMID:19695318 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of COL3A1 mRNA CTD PMID:19695318 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Commd8 COMM domain containing 8 decreases expression ISO Gold results in decreased expression of COMMD8 mRNA CTD PMID:25523186 NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617
JBrowse link
G Cox11 cytochrome c oxidase copper chaperone COX11 decreases expression ISO Gold results in decreased expression of COX11 mRNA CTD PMID:25523186 NCBI chr10:75,458,735...75,465,322
Ensembl chr10:75,458,749...75,465,322
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO Gold results in decreased expression of COX17 mRNA CTD PMID:25523186 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CPT1A mRNA CTD PMID:28433809 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CPT2 mRNA CTD PMID:28433809 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of CSF2 protein
Gold results in increased secretion of CSF2 protein
CTD PMID:22155353 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 increases secretion
multiple interactions
ISO Gold results in increased secretion of CSF3 protein
[Gold co-treated with Silicon Dioxide] results in increased secretion of CSF3 protein
CTD PMID:22155353 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Ctcf CCCTC-binding factor multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of CTCF mRNA CTD PMID:19695318 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Cux1 cut-like homeobox 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of CUX1 mRNA CTD PMID:19695318 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion
multiple interactions
ISO Gold results in increased secretion of CXCL10 protein
[Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL10 protein
CTD PMID:22155353 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases secretion
ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL2 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL2 protein
Gold results in increased secretion of CXCL2 protein
CTD PMID:19695318 PMID:22155353 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CXCL1 mRNA CTD PMID:19695318 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [[Gold results in decreased abundance of Glutathione] which results in increased abundance of Hydrogen Peroxide] which affects the localization of CYCS protein CTD PMID:21621595 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
ISO Gold analog results in increased activity of CYP1A1 protein
[Polyethyleneimine binds to Gold] which results in decreased expression of CYP1A1 mRNA
CTD PMID:20193702 PMID:28433809 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO Gold results in increased expression of CYP24A1 mRNA CTD PMID:29705079 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of CYP2D6 mRNA CTD PMID:28433809 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyth1 cytohesin 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of CYTH1 mRNA CTD PMID:19695318 NCBI chr10:103,402,727...103,485,826
Ensembl chr10:103,366,145...103,485,760
JBrowse link
G Dcp2 decapping mRNA 2 decreases expression ISO Gold results in decreased expression of DCP2 mRNA CTD PMID:25523186 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Ddc dopa decarboxylase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of DDC mRNA CTD PMID:19695318 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of DDIT3 mRNA CTD PMID:28433809 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of DDIT4 mRNA CTD PMID:19695318 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Defb1 defensin beta 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DEFB1 mRNA CTD PMID:28433809 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of DHCR24 mRNA
[Polyethyleneimine binds to Gold] which results in decreased expression of DHCR24 mRNA
CTD PMID:19695318 PMID:28433809 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dnah14 dynein axonemal heavy chain 14 decreases expression ISO Gold results in decreased expression of DNAH14 mRNA CTD PMID:25523186 NCBI chr13:93,322,653...93,540,706 JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of DNAJA3 mRNA CTD PMID:28433809 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 decreases expression ISO Gold results in decreased expression of DNAJB14 mRNA CTD PMID:25523186 NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 decreases expression ISO Gold results in decreased expression of DNAJB6 mRNA CTD PMID:25523186 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 decreases expression ISO Gold results in decreased expression of DNAJB9 mRNA CTD PMID:25523186 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 decreases expression ISO Gold results in decreased expression of DNAJC10 mRNA CTD PMID:25523186 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression ISO Gold results in decreased expression of DNAJC19 mRNA CTD PMID:25523186 NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
JBrowse link
G Dnajc21 DnaJ heat shock protein family (Hsp40) member C21 decreases expression ISO Gold results in decreased expression of DNAJC21 mRNA CTD PMID:25523186 NCBI chr 2:59,419,505...59,446,743
Ensembl chr 2:59,419,510...59,446,752
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DNAJC5 mRNA CTD PMID:28433809 NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP Gold inhibits the reaction [3-N-methylspiperone binds to DRD3 protein] CTD PMID:10215675 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions EXP Gold inhibits the reaction [3-N-methylspiperone binds to DRD4 protein] CTD PMID:10215675 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dsc2 desmocollin 2 increases expression ISO Gold results in increased expression of DSC2 mRNA CTD PMID:29705079 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Dsg2 desmoglein 2 increases expression ISO Gold results in increased expression of DSG2 mRNA CTD PMID:29705079 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Duox1 dual oxidase 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DUOX1 mRNA CTD PMID:28433809 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of DUOX2 mRNA CTD PMID:28433809 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of DUSP1 mRNA CTD PMID:19695318 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp11 dual specificity phosphatase 11 decreases expression ISO Gold results in decreased expression of DUSP11 mRNA CTD PMID:25523186 NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression ISO Gold results in decreased expression of DUT mRNA CTD PMID:25523186 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Dzip3 DAZ interacting zinc finger protein 3 decreases expression ISO Gold results in decreased expression of DZIP3 mRNA CTD PMID:25523186 NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of EDEM3 mRNA CTD PMID:28433809 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
JBrowse link
G Eea1 early endosome antigen 1 decreases expression ISO Gold results in decreased expression of EEA1 mRNA CTD PMID:25523186 NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta decreases expression ISO Gold analog results in decreased expression of EEF1D protein CTD PMID:24780912 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression ISO Gold analog results in decreased expression of EEF2 protein CTD PMID:24780912 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]; [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of RELA protein]; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]]; MAP2K1 inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of JUN protein]] CTD PMID:27634460 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of EID1 mRNA CTD PMID:19695318 NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked decreases expression ISO Gold results in decreased expression of EIF1AX mRNA CTD PMID:25523186 NCBI chr  X:35,498,698...35,513,402
Ensembl chr  X:35,498,517...35,513,335
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO Gold analog results in increased phosphorylation of EIF2AK3 protein CTD PMID:26551149 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Gold results in decreased expression of EIF4A2 mRNA CTD PMID:25523186 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in decreased expression of EIF4E protein CTD PMID:27470402 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 multiple interactions ISO [Quercetin analog co-treated with Gold analog] results in increased expression of EIF4EBP3 protein CTD PMID:27470402 NCBI chr18:28,263,089...28,268,033 JBrowse link
G Eif5b eukaryotic translation initiation factor 5B multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of EIF5B mRNA CTD PMID:28433809 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
JBrowse link
G Eno1 enolase 1 multiple interactions ISO Gold analog results in decreased expression of and results in increased phosphorylation of ENO1 protein CTD PMID:24780912 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased acetylation of and results in increased stability of EP300 protein]; [Polyethyleneimine binds to Gold] which results in decreased expression of EP300 mRNA; EP300 protein inhibits the reaction [[Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased expression of MMP9 protein]] CTD PMID:27634460 PMID:28433809 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epgn epithelial mitogen increases expression ISO Gold results in increased expression of EPGN mRNA CTD PMID:29705079 NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of EPHA1 mRNA CTD PMID:19695318 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of ERCC2 mRNA CTD PMID:28433809 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Gold analog results in increased phosphorylation of ERN1 protein CTD PMID:26551149 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Gold results in increased expression of ERO1A mRNA CTD PMID:29705079 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Gold results in decreased expression of ESCO2 mRNA CTD PMID:25523186 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Evi5 ecotropic viral integration site 5 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of EVI5 mRNA CTD PMID:19695318 NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678
JBrowse link
G Evx1 even-skipped homeobox 1 increases expression ISO Gold results in increased expression of EVX1 mRNA CTD PMID:25523186
G Fancl FA complementation group L decreases expression ISO Gold results in decreased expression of FANCL mRNA CTD PMID:25523186 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of FAS mRNA CTD PMID:28433809 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of FGF1 mRNA CTD PMID:19695318 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of FH mRNA CTD PMID:28433809 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 increases phosphorylation
decreases expression
ISO Gold analog results in increased phosphorylation of FKBP9 protein
Gold analog results in decreased expression of FKBP9 protein
CTD PMID:24780912 NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of FMO5 mRNA CTD PMID:28433809 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Gold co-treated with Silicon Dioxide] results in increased expression of FOS mRNA
Gold results in increased expression of FOS mRNA
CTD PMID:22155353 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Gold results in increased expression of FTH1 mRNA CTD PMID:29705079 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO Gold results in increased expression of FYB mRNA CTD PMID:29705079 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Fzd4 frizzled class receptor 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of FZD4 mRNA CTD PMID:19695318 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase decreases expression ISO Gold results in decreased expression of G2E3 mRNA CTD PMID:25523186 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO Gold results in decreased expression of GALNT1 mRNA CTD PMID:25523186 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of GANC mRNA CTD PMID:19695318 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO Gold analog results in decreased expression of GAPDH protein CTD PMID:24780912 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gca grancalcin decreases expression ISO Gold results in decreased expression of GCA mRNA CTD PMID:25523186 NCBI chr 3:47,297,320...47,328,581
Ensembl chr 3:47,297,383...47,328,581
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of GCDH mRNA CTD PMID:28433809 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
G Gmps guanine monophosphate synthase multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of GMPS mRNA CTD PMID:19695318 NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
JBrowse link
G Gng10 G protein subunit gamma 10 decreases expression ISO Gold results in decreased expression of GNG10 mRNA CTD PMID:25523186 NCBI chr 5:73,856,124...73,863,017
Ensembl chr 5:73,856,164...73,863,012
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression ISO Gold analog results in decreased expression of GOT2 protein CTD PMID:24780912 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpr182 G protein-coupled receptor 182 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of GPR182 mRNA CTD PMID:19695318 NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased activity of GPT protein]; [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in increased expression of GPT protein]
[Polyethyleneimine binds to Gold] which results in decreased expression of GPT mRNA
CTD PMID:27836789 PMID:28433809 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO Gold results in increased expression of GPX2 mRNA CTD PMID:25523186 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsn gelsolin decreases expression
increases degradation
ISO Gold analog results in decreased expression of GSN protein
Gold analog results in increased degradation of GSN protein
CTD PMID:24780912 PMID:26551149 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gstm4 glutathione S-transferase mu 4 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of GSTM4 mRNA CTD PMID:28433809 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Hat1 histone acetyltransferase 1 decreases expression ISO Gold results in decreased expression of HAT1 mRNA CTD PMID:25523186 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO [Polyethylene Glycols binds to Gold] which results in increased expression of HAVCR1 protein; [Polyethyleneimine binds to Gold] which results in increased expression of HAVCR1 protein; [Thioctic Acid binds to Gold] which results in increased expression of HAVCR1 protein CTD PMID:28433809 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 increases expression ISO Gold results in increased expression of HCAR2 mRNA CTD PMID:29705079 NCBI chr12:32,726,334...32,727,416
Ensembl chr12:32,726,184...32,728,504
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Gold results in decreased expression of HMGB2 mRNA CTD PMID:25523186 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Gold results in increased expression of HMOX1 mRNA CTD PMID:25523186 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression ISO Gold results in decreased expression of HPRT1 mRNA CTD PMID:25523186 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsbp1 heat shock factor binding protein 1 decreases expression ISO Gold results in decreased expression of HSBP1 mRNA CTD PMID:25523186 NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of HSF1 mRNA CTD PMID:28433809 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of HSP90AB1 mRNA CTD PMID:19695318 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 decreases expression ISO Gold results in decreased expression of HSPA13 mRNA CTD PMID:25523186 NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1A mRNA CTD PMID:28433809
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Polyethyleneimine binds to Gold] which results in decreased expression of HSPA1B mRNA CTD PMID:28433809 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPA4 mRNA CTD PMID:19695318 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO Gold analog results in increased expression of HSPA8 protein CTD PMID:24780912 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of HSPA9 mRNA CTD PMID:19695318 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in decreased expression of HSPB1 mRNA
[Polyethyleneimine binds to Gold] which results in decreased expression of HSPB1 mRNA
CTD PMID:19695318 PMID:28433809 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of HSPD1 mRNA CTD PMID:28433809 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Gold results in increased expression of HTATIP2 mRNA CTD PMID:29705079 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 decreases expression ISO Gold results in decreased expression of HTATSF1 mRNA CTD PMID:25523186 NCBI chr  X:134,935,426...134,949,607
Ensembl chr  X:134,935,426...134,949,607
JBrowse link
G Hyou1 hypoxia up-regulated 1 multiple interactions ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of HYOU1 mRNA CTD PMID:19695318 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO Gold analog results in decreased expression of and results in increased phosphorylation of IDH1 protein CTD PMID:24780912 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Polyethyleneimine binds to Gold] which results in increased expression of IDH3G mRNA CTD PMID:28433809 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Gold results in increased expression of IFNGR1 mRNA CTD PMID:29705079 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO Gold inhibits the reaction [IGF1 protein binds to IGF1R protein]; Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions ISO Gold inhibits the reaction [IGF2 protein binds to IGF1R protein] CTD PMID:9648927 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Gold results in decreased expression of IKZF2 mRNA CTD PMID:25523186 NCBI chr 9:71,042,440...71,191,296
Ensembl chr 9:71,042,440...71,190,867
JBrowse link
G Il10 interleukin 10 multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of IL10 protein
Gold results in increased secretion of IL10 protein
CTD PMID:22155353 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases secretion
ISO [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1A protein
Gold results in increased secretion of IL1A protein
CTD PMID:22155353 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of IL1B mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL1B protein
Gold results in increased secretion of IL1B protein
CTD PMID:19695318 PMID:22155353 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
ISO [Gold co-treated with Polyethylene Glycols] results in increased expression of IL6 mRNA; [Gold co-treated with Silicon Dioxide] results in increased secretion of IL6 protein
[Polyethylene Glycols binds to Gold] which results in increased expression of IL6 protein; [Polyethyleneimine binds to Gold] which results in increased expression of IL6 protein; [Thioctic Acid binds to Gold] which results in increased expression of IL6 protein
Gold results in increased secretion of IL6 protein
CTD PMID:19695318 PMID:22155353 PMID:28433809 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178