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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alkyl sulfate
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Accession:CHEBI:29281 term browser browse the term
Synonyms:related_synonym: alkyl sulfates
 alt_id: CHEBI:13810;   CHEBI:22325;   CHEBI:2583
 cyclic_relationship: is_conjugate_acid_of CHEBI:83414


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diethyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO diethyl sulfate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO diethyl sulfate results in increased expression of BAX protein CTD PMID:23830811 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO diethyl sulfate results in decreased expression of BCL2 protein CTD PMID:23830811 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression		 ISO diethyl sulfate results in increased cleavage of CASP3 protein
diethyl sulfate results in increased expression of CASP3 protein modified form		 CTD PMID:23830811 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccna2 cyclin A2 affects expression ISO diethyl sulfate affects the expression of CCNA2 protein CTD PMID:23887207 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 affects expression ISO diethyl sulfate affects the expression of CCNB1 protein CTD PMID:23887207 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdk2 cyclin dependent kinase 2 affects phosphorylation ISO diethyl sulfate affects the phosphorylation of CDK2 protein CTD PMID:23887207 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO diethyl sulfate affects the expression of CDK4 protein CTD PMID:23887207 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Chek1 checkpoint kinase 1 decreases expression
increases expression		 ISO diethyl sulfate results in decreased expression of CHEK1 protein modified form
diethyl sulfate results in increased expression of CHEK1 protein modified form		 CTD PMID:23830811 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 decreases expression
increases expression		 ISO diethyl sulfate results in decreased expression of CHEK2 protein modified form
diethyl sulfate results in increased expression of CHEK2 protein modified form		 CTD PMID:23830811 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO diethyl sulfate results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO diethyl sulfate results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO diethyl sulfate results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO diethyl sulfate results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression		 ISO diethyl sulfate results in decreased expression of TP53 protein
diethyl sulfate results in increased expression of TP53 protein		 CTD PMID:23830811 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
dimethyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 decreases expression ISO dimethyl sulfate results in decreased expression of DNMT1 protein CTD PMID:11912126 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO dimethyl sulfate inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA] CTD PMID:20888885 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases alkylation ISO dimethyl sulfate results in increased alkylation of MGMT protein CTD PMID:8823159 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases response to substance ISO MPG protein results in increased susceptibility to dimethyl sulfate CTD PMID:15299078 NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO dimethyl sulfate results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
dodecyl hydrogen sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity		 EXP capsazepine inhibits the reaction [dodecyl sulfate results in increased activity of TRPV1 protein] CTD PMID:19540328 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      chemical role 19422
        catalyst 8293
          sulfuric acid 8242
            sulfuric acid derivative 8242
              organic sulfate 2274
                alkyl sulfate 23
                  (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                  (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                  (2Z)-2-[(sulfooxy)methyl]but-2-enoic acid 0
                  (4R)-4,8-dimethylnonyl hydrogen sulfate 0
                  11-sulfooxy-9,10-dihydrojasmonic acid 0
                  12-sulfooxy-9,10-dihydrojasmonic acid 0
                  2,6-dimethylheptyl hydrogen sulfate + 0
                  2-(sulfooxy)pentanoic acid 0
                  2-[(sulfooxy)methyl]butanoic acid 0
                  2-butyloctyl hydrogen sulfate 0
                  2-ethylhexyl sulfate 0
                  3-Sulfooxybutanoic acid 0
                  3-methyl-4-(sulfooxy)but-2-enoic acid 0
                  4-(sulfooxy)butanoic acid 0
                  4-Hydroxy-5-(3'-hydroxyphenyl)-valeric acid-3'-O-sulphate 0
                  4-Hydroxy-5-(phenyl)-valeric acid-O-sulphate 0
                  5-(3-methoxyphenyl)-4-(sulfooxy)pentanoic acid 0
                  5-(sulfooxy)pentanoic acid 0
                  7-methyloctyl hydrogen sulfate 0
                  SCHEMBL9567921 0
                  decyl hydrogen sulfate 0
                  diethyl sulfate 18
                  dimethyl sulfate 5
                  dodecyl hydrogen sulfate 1
                  glycosmisic acid sulfate 0
                  methyl sulfate 0
                  octyl hydrogen sulfate 0
                  poly(vinyl sulfate) 0
                  tetradecyl sulfonic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      chalcogen 19515
                        oxygen atom 19520
                          oxygen molecular entity 19490
                            hydroxides 19300
                              oxoacid 18725
                                chalcogen oxoacid 13752
                                  sulfur oxoacid 13540
                                    sulfuric acid 8242
                                      sulfuric acid derivative 8242
                                        sulfates 8237
                                          organic sulfate 2274
                                            alkyl sulfate 23
                                              (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                              (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                              (2Z)-2-[(sulfooxy)methyl]but-2-enoic acid 0
                                              (4R)-4,8-dimethylnonyl hydrogen sulfate 0
                                              11-sulfooxy-9,10-dihydrojasmonic acid 0
                                              12-sulfooxy-9,10-dihydrojasmonic acid 0
                                              2,6-dimethylheptyl hydrogen sulfate + 0
                                              2-(sulfooxy)pentanoic acid 0
                                              2-[(sulfooxy)methyl]butanoic acid 0
                                              2-butyloctyl hydrogen sulfate 0
                                              2-ethylhexyl sulfate 0
                                              3-Sulfooxybutanoic acid 0
                                              3-methyl-4-(sulfooxy)but-2-enoic acid 0
                                              4-(sulfooxy)butanoic acid 0
                                              4-Hydroxy-5-(3'-hydroxyphenyl)-valeric acid-3'-O-sulphate 0
                                              4-Hydroxy-5-(phenyl)-valeric acid-O-sulphate 0
                                              5-(3-methoxyphenyl)-4-(sulfooxy)pentanoic acid 0
                                              5-(sulfooxy)pentanoic acid 0
                                              7-methyloctyl hydrogen sulfate 0
                                              SCHEMBL9567921 0
                                              decyl hydrogen sulfate 0
                                              diethyl sulfate 18
                                              dimethyl sulfate 5
                                              dodecyl hydrogen sulfate 1
                                              glycosmisic acid sulfate 0
                                              methyl sulfate 0
                                              octyl hydrogen sulfate 0
                                              poly(vinyl sulfate) 0
                                              tetradecyl sulfonic acid 0
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