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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkyl sulfate
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Accession:CHEBI:29281 term browser browse the term
Synonyms:related_synonym: alkyl sulfates
 alt_id: CHEBI:13810;   CHEBI:22325;   CHEBI:2583
 cyclic_relationship: is_conjugate_acid_of CHEBI:83414


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diethyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO diethyl sulfate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO diethyl sulfate results in increased expression of BAX protein CTD PMID:23830811 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO diethyl sulfate results in decreased expression of BCL2 protein CTD PMID:23830811 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression
ISO diethyl sulfate results in increased cleavage of CASP3 protein
diethyl sulfate results in increased expression of CASP3 protein modified form
CTD PMID:23830811 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccna2 cyclin A2 affects expression ISO diethyl sulfate affects the expression of CCNA2 protein CTD PMID:23887207 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 affects expression ISO diethyl sulfate affects the expression of CCNB1 protein CTD PMID:23887207 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdk2 cyclin dependent kinase 2 affects phosphorylation ISO diethyl sulfate affects the phosphorylation of CDK2 protein CTD PMID:23887207 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO diethyl sulfate affects the expression of CDK4 protein CTD PMID:23887207 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression
increases expression
ISO diethyl sulfate results in decreased expression of CHEK1 protein modified form
diethyl sulfate results in increased expression of CHEK1 protein modified form
CTD PMID:23830811 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 decreases expression
increases expression
ISO diethyl sulfate results in decreased expression of CHEK2 protein modified form
diethyl sulfate results in increased expression of CHEK2 protein modified form
CTD PMID:23830811 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO diethyl sulfate results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO diethyl sulfate results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO diethyl sulfate results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ins2 insulin 2 multiple interactions ISO diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; diethyl sulfate inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO diethyl sulfate results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression
ISO diethyl sulfate results in decreased expression of TP53 protein
diethyl sulfate results in increased expression of TP53 protein
CTD PMID:23830811 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
dimethyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 decreases expression ISO dimethyl sulfate results in decreased expression of DNMT1 protein CTD PMID:11912126 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO dimethyl sulfate inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA] CTD PMID:20888885 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases alkylation ISO dimethyl sulfate results in increased alkylation of MGMT protein CTD PMID:8823159 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases response to substance ISO MPG protein results in increased susceptibility to dimethyl sulfate CTD PMID:15299078 NCBI chr10:15,661,768...15,667,995
Ensembl chr10:15,661,608...15,668,022
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO dimethyl sulfate results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
dodecyl hydrogen sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
EXP capsazepine inhibits the reaction [dodecyl sulfate results in increased activity of TRPV1 protein] CTD PMID:19540328 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      chemical role 19248
        catalyst 8048
          sulfuric acid 8009
            sulfuric acid derivative 8009
              organic sulfate 1933
                alkyl sulfate 23
                  (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                  (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                  (4R)-4,8-dimethylnonyl hydrogen sulfate 0
                  11-sulfooxy-9,10-dihydrojasmonic acid 0
                  12-sulfooxy-9,10-dihydrojasmonic acid 0
                  2,6-dimethylheptyl hydrogen sulfate + 0
                  2-butyloctyl hydrogen sulfate 0
                  2-ethylhexyl sulfate 0
                  4-Hydroxy-5-(3'-hydroxyphenyl)-valeric acid-3'-O-sulphate 0
                  4-Hydroxy-5-(phenyl)-valeric acid-O-sulphate 0
                  7-methyloctyl hydrogen sulfate 0
                  decyl hydrogen sulfate 0
                  diethyl sulfate 18
                  dimethyl sulfate 5
                  dodecyl hydrogen sulfate 1
                  glycosmisic acid sulfate 0
                  methyl sulfate 0
                  octyl hydrogen sulfate 0
                  poly(vinyl sulfate) 0
                  tetradecyl sulfonic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      chalcogen 19360
                        oxygen atom 19321
                          oxygen molecular entity 19321
                            hydroxides 19066
                              oxoacid 18192
                                chalcogen oxoacid 11479
                                  sulfur oxoacid 11082
                                    sulfuric acid 8009
                                      sulfuric acid derivative 8009
                                        sulfates 8006
                                          organic sulfate 1933
                                            alkyl sulfate 23
                                              (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                              (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                              (4R)-4,8-dimethylnonyl hydrogen sulfate 0
                                              11-sulfooxy-9,10-dihydrojasmonic acid 0
                                              12-sulfooxy-9,10-dihydrojasmonic acid 0
                                              2,6-dimethylheptyl hydrogen sulfate + 0
                                              2-butyloctyl hydrogen sulfate 0
                                              2-ethylhexyl sulfate 0
                                              4-Hydroxy-5-(3'-hydroxyphenyl)-valeric acid-3'-O-sulphate 0
                                              4-Hydroxy-5-(phenyl)-valeric acid-O-sulphate 0
                                              7-methyloctyl hydrogen sulfate 0
                                              decyl hydrogen sulfate 0
                                              diethyl sulfate 18
                                              dimethyl sulfate 5
                                              dodecyl hydrogen sulfate 1
                                              glycosmisic acid sulfate 0
                                              methyl sulfate 0
                                              octyl hydrogen sulfate 0
                                              poly(vinyl sulfate) 0
                                              tetradecyl sulfonic acid 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.