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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:manganese(2+)
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Accession:CHEBI:29035 term browser browse the term
Definition:A divalent metal cation in which the metal is manganese.
Synonyms:exact_synonym: manganese(2+) ion;   manganese(II) cation
 related_synonym: Formula=Mn;   InChI=1S/Mn/q+2;   InChIKey=WAEMQWOKJMHJLA-UHFFFAOYSA-N;   MANGANESE (II) ION;   Mn(2+);   Mn(II);   Mn2+;   SMILES=[Mn++];   manganese(II);   manganese, ion (Mn2+);   manganous ion
 alt_id: CHEBI:21435;   CHEBI:25156;   CHEBI:49749
 xref: CAS:16397-91-4;   Gmelin:6858
 xref_mesh: MESH:D008345
 xref: PDBeChem:MN


show annotations for term's descendants           Sort by:
manganese(II) sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression EXP manganese sulfate results in increased expression of CXCL2 mRNA CTD PMID:11708899 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP manganese sulfate results in decreased expression of GLUL mRNA; manganese sulfate results in decreased expression of GLUL protein CTD PMID:16943606 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression EXP manganese sulfate results in increased expression of HSPA4 mRNA CTD PMID:26097037 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of IL6 protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:15601679 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mt1 metallothionein 1 decreases expression EXP manganese sulfate results in decreased expression of MT1A mRNA CTD PMID:12387356 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression EXP manganese sulfate results in decreased expression of NOS1 mRNA CTD PMID:16476481 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP manganese sulfate results in decreased expression of SLC1A3 mRNA CTD PMID:12387356 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP manganese sulfate results in decreased expression of TGFB1 mRNA CTD PMID:16476481 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase decreases expression EXP manganese sulfate results in decreased expression of TH mRNA CTD PMID:16943606 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of TNF protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:15601679 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      biological role 19891
        biochemical role 19598
          cofactor 16592
            manganese(2+) 10
              manganese(II) sulfate + 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  metal atom 17870
                    transition element atom 17227
                      d-block element atom 17222
                        manganese group element atom 2100
                          manganese atom 2100
                            manganese molecular entity 2100
                              elemental manganese 452
                                manganese cation 10
                                  manganese(2+) 10
                                    manganese(II) sulfate + 10
paths to the root