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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hexane
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Accession:CHEBI:29021 term browser browse the term
Definition:An unbranched alkane containing six carbon atoms.
Synonyms:related_synonym: CH3-[CH2]4-CH3;   Formula=C6H14;   Hexan;   InChI=1S/C6H14/c1-3-5-6-4-2/h3-6H2,1-2H3;   InChIKey=VLKZOEOYAKHREP-UHFFFAOYSA-N;   SMILES=CCCCCC;   n-Hexane
 alt_id: CHEBI:10606;   CHEBI:24566;   CHEBI:24568;   CHEBI:43148
 xref: Beilstein:1730733;   CAS:110-54-3;   DrugBank:DB02764;   Gmelin:1985;   HMDB:HMDB0029600;   KEGG:C11271;   LIPID_MAPS_instance:LMFA11000007
 xref_mesh: MESH:C026385
 xref: PDBeChem:HEX;   PMID:11292478;   PMID:11684179;   PMID:11886809;   PMID:15325316;   PMID:18231777;   PMID:19229957;   PMID:19384711;   PMID:23452516;   PMID:23567114;   PMID:23620851;   PMID:23740543;   PMID:23822317;   PMID:23931182;   PMID:7612176;   Reaxys:1730733;   Wikipedia:Hexane


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hexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in decreased expression of ADRB1 mRNA CTD PMID:30503853 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in decreased expression of ADRB2 mRNA CTD PMID:30503853 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B increases expression EXP n-hexane results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 increases expression EXP n-hexane results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412 		JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 increases expression EXP n-hexane results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 increases expression EXP n-hexane results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated decreases methylation ISO n-hexane results in decreased methylation of ALPL promoter CTD PMID:23740543 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G AREG amphiregulin decreases methylation ISO n-hexane results in decreased methylation of AREG promoter CTD PMID:23740543 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ARHGAP45 Rho GTPase activating protein 45 increases methylation ISO n-hexane results in increased methylation of ARHGAP45 promoter CTD PMID:23740543 NCBI chr19:1,065,959...1,086,628
Ensembl chr19:1,065,923...1,086,628 		JBrowse link
G ATL2 atlastin GTPase 2 decreases methylation ISO n-hexane results in decreased methylation of ATL2 promoter CTD PMID:23740543 NCBI chr 2:38,293,954...38,378,584
Ensembl chr 2:38,293,954...38,377,285 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression ISO n-hexane metabolite results in increased expression of BAX protein CTD PMID:17492505 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression ISO n-hexane metabolite results in increased expression of BCL2 protein CTD PMID:17492505 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCLAF1 BCL2 associated transcription factor 1 decreases methylation ISO n-hexane results in decreased methylation of BCLAF1 promoter CTD PMID:23740543 NCBI chr 6:136,256,627...136,289,846
Ensembl chr 6:136,256,627...136,289,851 		JBrowse link
G C19orf44 chromosome 19 open reading frame 44 increases methylation ISO n-hexane results in increased methylation of C16H19ORF44 promoter CTD PMID:23740543 NCBI chr19:16,496,394...16,521,352
Ensembl chr19:16,496,394...16,521,352 		JBrowse link
G CALR3 calreticulin 3 increases methylation ISO n-hexane results in increased methylation of CALR3 promoter CTD PMID:23740543 NCBI chr19:16,479,061...16,496,167
Ensembl chr19:16,479,061...16,496,167 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 decreases methylation ISO n-hexane results in decreased methylation of CAP1 promoter CTD PMID:23740543 NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649 		JBrowse link
G CASP3 caspase 3 increases expression ISO n-hexane metabolite results in increased expression of CASP3 protein CTD PMID:17492505 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CCNK cyclin K decreases methylation ISO n-hexane results in decreased methylation of CCNK promoter CTD PMID:23740543 NCBI chr14:99,481,409...99,512,440
Ensembl chr14:99,481,169...99,535,044 		JBrowse link
G CFAP20 cilia and flagella associated protein 20 decreases methylation ISO n-hexane results in decreased methylation of CFAP20 promoter CTD PMID:23740543 NCBI chr16:58,113,592...58,129,381
Ensembl chr16:58,113,592...58,129,381 		JBrowse link
G CHIC2 cysteine rich hydrophobic domain 2 decreases methylation ISO n-hexane results in decreased methylation of CHIC2 promoter CTD PMID:23740543 NCBI chr 4:54,009,789...54,091,879
Ensembl chr 4:54,009,789...54,064,605 		JBrowse link
G CHMP2A charged multivesicular body protein 2A decreases methylation ISO n-hexane results in decreased methylation of CHMP2A promoter CTD PMID:23740543 NCBI chr19:58,551,566...58,555,105
Ensembl chr19:58,551,452...58,555,105 		JBrowse link
G CLCN2 chloride voltage-gated channel 2 decreases methylation ISO n-hexane results in decreased methylation of CLCN2 promoter CTD PMID:23740543 NCBI chr 3:184,346,185...184,361,605
Ensembl chr 3:184,346,185...184,361,650 		JBrowse link
G COPRS coordinator of PRMT5 and differentiation stimulator decreases methylation ISO n-hexane results in decreased methylation of COPRS promoter CTD PMID:23740543 NCBI chr17:31,851,871...31,859,244
Ensembl chr17:31,851,871...31,859,291 		JBrowse link
G COPZ2 COPI coat complex subunit zeta 2 decreases methylation ISO n-hexane results in decreased methylation of COPZ2 promoter CTD PMID:23740543 NCBI chr17:48,026,167...48,048,053
Ensembl chr17:48,026,167...48,038,030 		JBrowse link
G CRPPA CDP-L-ribitol pyrophosphorylase A decreases methylation ISO n-hexane results in decreased methylation of CRPPA promoter CTD PMID:23740543 NCBI chr 7:16,087,525...16,421,538
Ensembl chr 7:16,087,525...16,502,504 		JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 increases methylation ISO n-hexane results in increased methylation of CSPG4 promoter CTD PMID:23740543 NCBI chr15:75,674,322...75,713,466
Ensembl chr15:75,674,322...75,712,848 		JBrowse link
G CTHRC1 collagen triple helix repeat containing 1 decreases methylation ISO n-hexane results in decreased methylation of CTHRC1 promoter CTD PMID:23740543 NCBI chr 8:103,371,538...103,382,989
Ensembl chr 8:103,371,538...103,382,989 		JBrowse link
G CUL4A cullin 4A decreases methylation ISO n-hexane results in decreased methylation of CUL4A promoter CTD PMID:23740543 NCBI chr13:113,208,193...113,267,108
Ensembl chr13:113,208,193...113,267,108 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in increased expression of CXCL8 mRNA CTD PMID:30503853 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 affects expression
affects methylation		 ISO n-hexane affects the expression of CYP11A1 mRNA; n-hexane affects the expression of CYP11A1 protein
n-hexane affects the methylation of CYP11A1 promoter		 CTD PMID:26410608 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 affects expression
affects methylation		 ISO n-hexane affects the expression of CYP17A1 mRNA; n-hexane affects the expression of CYP17A1 protein
n-hexane affects the methylation of CYP17A1 promoter		 CTD PMID:26410608 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases hydroxylation
multiple interactions		 ISO CYP1A1 protein results in increased hydroxylation of n-hexane
diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein]; n-hexane results in increased expression of and results in increased activity of CYP1A1 protein		 CTD PMID:16484137 PMID:28115069 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases hydroxylation
multiple interactions		 ISO CYP1A2 protein results in increased hydroxylation of n-hexane
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein]; n-hexane results in increased expression of and results in increased activity of CYP1A2 protein		 CTD PMID:16484137 PMID:28115069 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases hydroxylation EXP CYP2B1 protein results in increased hydroxylation of n-hexane; CYP2B6 protein results in increased hydroxylation of n-hexane CTD PMID:16484137 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects response to substance
multiple interactions
increases metabolic processing
increases hydroxylation		 EXP
ISO		 CYP2E1 gene polymorphism affects the susceptibility to n-hexane
diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]; n-hexane results in increased expression of and results in increased activity of CYP2E1 protein
CYP2E1 protein results in increased metabolism of n-hexane
CYP2E1 protein results in increased hydroxylation of n-hexane		 CTD PMID:11201664 PMID:16484137 PMID:28115069 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DIP2C disco interacting protein 2 homolog C decreases methylation ISO n-hexane results in decreased methylation of DIP2C promoter CTD PMID:23740543 NCBI chr10:274,201...689,668
Ensembl chr10:274,201...689,668 		JBrowse link
G DNMT1 DNA methyltransferase 1 decreases methylation ISO n-hexane results in decreased methylation of DNMT1 promoter CTD PMID:23740543 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha decreases methylation ISO n-hexane results in decreased methylation of DNMT3A promoter CTD PMID:23740543 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNTTIP1 deoxynucleotidyltransferase terminal interacting protein 1 decreases methylation ISO n-hexane results in decreased methylation of DNTTIP1 promoter CTD PMID:23740543 NCBI chr20:45,791,954...45,811,418
Ensembl chr20:45,791,954...45,811,427 		JBrowse link
G DRD5 dopamine receptor D5 decreases methylation ISO n-hexane results in decreased methylation of DRD5 promoter CTD PMID:23740543 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G E2F3 E2F transcription factor 3 decreases methylation ISO n-hexane results in decreased methylation of E2F3 promoter CTD PMID:23740543 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714 		JBrowse link
G EPN3 epsin 3 decreases methylation ISO n-hexane results in decreased methylation of EPN3 promoter CTD PMID:23740543 NCBI chr17:50,532,735...50,543,750
Ensembl chr17:50,532,682...50,543,750 		JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase increases methylation ISO n-hexane results in increased methylation of FAM20A promoter CTD PMID:23740543 NCBI chr17:68,535,116...68,601,367
Ensembl chr17:68,535,113...68,601,367 		JBrowse link
G FECH ferrochelatase increases expression EXP n-hexane results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732 		JBrowse link
G FGFBP1 fibroblast growth factor binding protein 1 decreases methylation ISO n-hexane results in decreased methylation of FGFBP1 promoter CTD PMID:23740543 NCBI chr 4:15,935,577...15,938,740
Ensembl chr 4:15,935,577...15,938,740 		JBrowse link
G FJX1 four-jointed box kinase 1 decreases methylation ISO n-hexane results in decreased methylation of FJX1 promoter CTD PMID:23740543 NCBI chr11:35,618,460...35,620,865
Ensembl chr11:35,618,460...35,620,865 		JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 decreases methylation ISO n-hexane results in decreased methylation of FMO3 promoter CTD PMID:23740543 NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819 		JBrowse link
G FOXI1 forkhead box I1 decreases methylation ISO n-hexane results in decreased methylation of FOXI1 promoter CTD PMID:23740543 NCBI chr 5:170,105,897...170,109,737
Ensembl chr 5:170,105,897...170,109,734 		JBrowse link
G FTL ferritin light chain increases expression EXP n-hexane results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases expression EXP n-hexane results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 decreases methylation ISO n-hexane results in decreased methylation of GALNT17 promoter CTD PMID:23740543 NCBI chr 7:71,132,144...71,713,599
Ensembl chr 7:71,132,144...71,713,600 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit increases expression EXP n-hexane results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression EXP n-hexane results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GLRX2 glutaredoxin 2 decreases methylation ISO n-hexane results in decreased methylation of GLRX2 promoter CTD PMID:23740543 NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114 		JBrowse link
G GNA14 G protein subunit alpha 14 decreases methylation ISO n-hexane results in decreased methylation of GNA14 promoter CTD PMID:23740543 NCBI chr 9:77,423,079...77,648,322
Ensembl chr 9:77,423,079...77,648,322 		JBrowse link
G GNAQ G protein subunit alpha q decreases methylation ISO n-hexane results in decreased methylation of GNAQ promoter CTD PMID:23740543 NCBI chr 9:77,716,097...78,031,811
Ensembl chr 9:77,716,097...78,031,811 		JBrowse link
G GOSR1 golgi SNAP receptor complex member 1 decreases methylation ISO n-hexane results in decreased methylation of GOSR1 promoter CTD PMID:23740543 NCBI chr17:30,477,408...30,527,592
Ensembl chr17:30,477,362...30,527,592 		JBrowse link
G GRM6 glutamate metabotropic receptor 6 decreases methylation ISO n-hexane results in decreased methylation of GRM6 promoter CTD PMID:23740543 NCBI chr 5:178,978,327...178,995,320
Ensembl chr 5:178,977,587...178,996,206 		JBrowse link
G GSR glutathione-disulfide reductase increases expression EXP n-hexane results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions		 EXP n-hexane results in increased expression of HMOX1 mRNA
[Particulate Matter co-treated with n-hexane] results in increased expression of HMOX1 mRNA		 CTD PMID:20566472 PMID:30503853 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HOOK1 hook microtubule tethering protein 1 decreases methylation ISO n-hexane results in decreased methylation of HOOK1 promoter CTD PMID:23740543 NCBI chr 1:59,814,949...59,876,322
Ensembl chr 1:59,814,786...59,876,322 		JBrowse link
G HP1BP3 heterochromatin protein 1 binding protein 3 decreases methylation ISO n-hexane results in decreased methylation of HP1BP3 promoter CTD PMID:23740543 NCBI chr 1:20,740,266...20,787,307
Ensembl chr 1:20,740,266...20,787,323 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA; carazolol promotes the reaction [[Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA] CTD PMID:30503853 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in increased expression of IL1B mRNA CTD PMID:30503853 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 increases expression ISO n-hexane results in increased expression of IL6 protein CTD PMID:23353815 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ING2 inhibitor of growth family member 2 decreases methylation ISO n-hexane results in decreased methylation of ING2 promoter CTD PMID:23740543 NCBI chr 4:183,505,058...183,512,429
Ensembl chr 4:183,505,058...183,512,429 		JBrowse link
G KCNK1 potassium two pore domain channel subfamily K member 1 increases methylation ISO n-hexane results in increased methylation of KCNK1 promoter CTD PMID:23740543 NCBI chr 1:233,614,106...233,672,514
Ensembl chr 1:233,614,106...233,672,514 		JBrowse link
G KHDRBS1 KH RNA binding domain containing, signal transduction associated 1 decreases methylation ISO n-hexane results in decreased methylation of KHDRBS1 promoter CTD PMID:23740543 NCBI chr 1:32,013,868...32,060,850
Ensembl chr 1:32,013,868...32,060,850 		JBrowse link
G KIAA1143 KIAA1143 increases methylation ISO n-hexane results in increased methylation of RGD1311745 promoter CTD PMID:23740543 NCBI chr 3:44,748,744...44,761,619
Ensembl chr 3:44,737,661...44,761,619 		JBrowse link
G KIF15 kinesin family member 15 increases methylation ISO n-hexane results in increased methylation of KIF15 promoter CTD PMID:23740543 NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376 		JBrowse link
G KLHL21 kelch like family member 21 decreases methylation ISO n-hexane results in decreased methylation of KLHL21 promoter CTD PMID:23740543 NCBI chr 1:6,590,724...6,602,869
Ensembl chr 1:6,590,724...6,614,607 		JBrowse link
G KRT84 keratin 84 decreases methylation ISO n-hexane results in decreased methylation of KRT84 promoter CTD PMID:23740543 NCBI chr12:52,377,812...52,386,977
Ensembl chr12:52,377,812...52,385,652 		JBrowse link
G LETM2 leucine zipper and EF-hand containing transmembrane protein 2 decreases methylation ISO n-hexane results in decreased methylation of LETM2 promoter CTD PMID:23740543 NCBI chr 8:38,382,431...38,409,527
Ensembl chr 8:38,386,207...38,409,527 		JBrowse link
G LOXL4 lysyl oxidase like 4 increases methylation ISO n-hexane results in increased methylation of LOXL4 promoter CTD PMID:23740543 NCBI chr10:98,247,690...98,268,194
Ensembl chr10:98,247,690...98,268,194 		JBrowse link
G LRFN1 leucine rich repeat and fibronectin type III domain containing 1 increases methylation ISO n-hexane results in increased methylation of LRFN1 promoter CTD PMID:23740543 NCBI chr19:39,306,566...39,320,863
Ensembl chr19:39,306,566...39,320,863 		JBrowse link
G LRFN3 leucine rich repeat and fibronectin type III domain containing 3 decreases methylation ISO n-hexane results in decreased methylation of LRFN3 promoter CTD PMID:23740543 NCBI chr19:35,936,374...35,946,624
Ensembl chr19:35,935,358...35,946,624 		JBrowse link
G MAFG MAF bZIP transcription factor G increases expression EXP n-hexane results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735 		JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 increases methylation ISO n-hexane results in increased methylation of MAGI2 promoter CTD PMID:23740543 NCBI chr 7:78,017,055...79,453,667
Ensembl chr 7:78,017,055...79,453,667 		JBrowse link
G MARCHF8 membrane associated ring-CH-type finger 8 decreases methylation ISO n-hexane results in decreased methylation of MARCHF8 promoter CTD PMID:23740543 NCBI chr10:45,454,585...45,594,907
Ensembl chr10:45,454,585...45,594,906 		JBrowse link
G MAU2 MAU2 sister chromatid cohesion factor decreases methylation ISO n-hexane results in decreased methylation of MAU2 promoter CTD PMID:23740543 NCBI chr19:19,320,829...19,358,754
Ensembl chr19:19,320,829...19,358,754 		JBrowse link
G MDK midkine decreases methylation ISO n-hexane results in decreased methylation of MDK promoter CTD PMID:23740543 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837 		JBrowse link
G ME1 malic enzyme 1 increases expression EXP n-hexane results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MEI1 meiotic double-stranded break formation protein 1 decreases methylation ISO n-hexane results in decreased methylation of MEI1 promoter CTD PMID:23740543 NCBI chr22:41,699,503...41,799,454
Ensembl chr22:41,699,503...41,799,456 		JBrowse link
G MFAP2 microfibril associated protein 2 decreases methylation ISO n-hexane results in decreased methylation of MFAP2 promoter CTD PMID:23740543 NCBI chr 1:16,974,502...16,981,583
Ensembl chr 1:16,974,502...16,980,632 		JBrowse link
G MIP major intrinsic protein of lens fiber increases methylation ISO n-hexane results in increased methylation of MIP promoter CTD PMID:23740543 NCBI chr12:56,449,502...56,456,553
Ensembl chr12:56,449,502...56,469,166 		JBrowse link
G MPPED2 metallophosphoesterase domain containing 2 decreases methylation ISO n-hexane results in decreased methylation of MPPED2 promoter CTD PMID:23740543 NCBI chr11:30,384,079...30,586,993
Ensembl chr11:30,384,493...30,586,872 		JBrowse link
G NDUFB4 NADH:ubiquinone oxidoreductase subunit B4 decreases methylation ISO n-hexane results in decreased methylation of NDUFB4 promoter CTD PMID:23740543 NCBI chr 3:120,596,336...120,602,507
Ensembl chr 3:120,596,328...120,602,507 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 decreases methylation ISO n-hexane results in decreased methylation of NDUFB8 promoter CTD PMID:23740543 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000 		JBrowse link
G NFATC2IP nuclear factor of activated T cells 2 interacting protein increases methylation ISO n-hexane results in increased methylation of NFATC2IP promoter CTD PMID:23740543 NCBI chr16:28,950,937...28,967,092
Ensembl chr16:28,950,807...28,967,092 		JBrowse link
G NPEPL1 aminopeptidase like 1 increases methylation ISO n-hexane results in increased methylation of NPEPL1 promoter CTD PMID:23740543 NCBI chr20:58,689,131...58,715,844
Ensembl chr20:58,689,131...58,719,238 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression EXP n-hexane results in increased expression of NQO1 mRNA CTD PMID:20566472 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G ODC1 ornithine decarboxylase 1 decreases methylation ISO n-hexane results in decreased methylation of ODC1 promoter CTD PMID:23740543 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G PCID2 PCI domain containing 2 decreases methylation ISO n-hexane results in decreased methylation of PCID2 promoter CTD PMID:23740543 NCBI chr13:113,165,002...113,208,669
Ensembl chr13:113,177,536...113,208,715 		JBrowse link
G PGD phosphogluconate dehydrogenase increases expression EXP n-hexane results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511 		JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 decreases methylation ISO n-hexane results in decreased methylation of PHLDA1 promoter CTD PMID:23740543 NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776 		JBrowse link
G POGLUT3 protein O-glucosyltransferase 3 decreases methylation ISO n-hexane results in decreased methylation of POGLUT3 promoter CTD PMID:23740543 NCBI chr11:108,472,116...108,498,384
Ensembl chr11:108,472,112...108,498,405 		JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta decreases methylation ISO n-hexane results in decreased methylation of PPP1CB promoter CTD PMID:23740543 NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940 		JBrowse link
G PROK2 prokineticin 2 decreases methylation ISO n-hexane results in decreased methylation of PROK2 promoter CTD PMID:23740543 NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206 		JBrowse link
G PRPF19 pre-mRNA processing factor 19 decreases methylation ISO n-hexane results in decreased methylation of PRPF19 promoter CTD PMID:23740543 NCBI chr11:60,890,547...60,906,585
Ensembl chr11:60,890,547...60,906,585 		JBrowse link
G PRPS2 phosphoribosyl pyrophosphate synthetase 2 decreases methylation ISO n-hexane results in decreased methylation of PRPS2 promoter CTD PMID:23740543 NCBI chr  X:12,791,412...12,824,222
Ensembl chr  X:12,791,355...12,824,222 		JBrowse link
G PTGR1 prostaglandin reductase 1 increases expression EXP n-hexane results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in increased expression of PTGS2 mRNA CTD PMID:30503853 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RAB5B RAB5B, member RAS oncogene family decreases methylation ISO n-hexane results in decreased methylation of RAB5B promoter CTD PMID:23740543 NCBI chr12:55,973,949...55,996,683
Ensembl chr12:55,973,913...55,996,683 		JBrowse link
G RABL6 RAB, member RAS oncogene family like 6 decreases methylation ISO n-hexane results in decreased methylation of RABL6 promoter CTD PMID:23740543 NCBI chr 9:136,807,948...136,841,187
Ensembl chr 9:136,807,943...136,841,187 		JBrowse link
G RALY RALY heterogeneous nuclear ribonucleoprotein decreases methylation ISO n-hexane results in decreased methylation of RALY promoter CTD PMID:23740543 NCBI chr20:33,993,911...34,084,884
Ensembl chr20:33,993,646...34,108,308 		JBrowse link
G REEP1 receptor accessory protein 1 decreases methylation ISO n-hexane results in decreased methylation of REEP1 promoter CTD PMID:23740543 NCBI chr 2:86,213,993...86,338,083
Ensembl chr 2:86,213,993...86,338,083 		JBrowse link
G RP2 RP2 activator of ARL3 GTPase decreases methylation ISO n-hexane results in decreased methylation of RP2 promoter CTD PMID:23740543 NCBI chr  X:46,837,043...46,882,358
Ensembl chr  X:46,837,043...46,882,358 		JBrowse link
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog increases methylation ISO n-hexane results in increased methylation of RPRM promoter CTD PMID:23740543 NCBI chr 2:153,477,338...153,478,762
Ensembl chr 2:153,477,338...153,478,762 		JBrowse link
G RPS6KA5 ribosomal protein S6 kinase A5 decreases methylation ISO n-hexane results in decreased methylation of RPS6KA5 promoter CTD PMID:23740543 NCBI chr14:90,847,861...91,060,641
Ensembl chr14:90,847,861...91,060,641 		JBrowse link
G SAXO5 stabilizer of axonemal microtubules 5 decreases methylation ISO n-hexane results in decreased methylation of SAXO5 promoter CTD PMID:23740543 NCBI chr19:7,497,548...7,508,450
Ensembl chr19:7,492,976...7,508,450 		JBrowse link
G SELENOV selenoprotein V decreases methylation ISO n-hexane results in decreased methylation of SELENOV promoter CTD PMID:23740543 NCBI chr19:39,515,113...39,520,686
Ensembl chr19:39,515,139...39,520,675 		JBrowse link
G SEMA5B semaphorin 5B decreases methylation ISO n-hexane results in decreased methylation of SEMA5B promoter CTD PMID:23740543 NCBI chr 3:122,909,082...123,028,605
Ensembl chr 3:122,909,082...123,028,605 		JBrowse link
G SERPINB2 serpin family B member 2 multiple interactions EXP [Particulate Matter co-treated with n-hexane] results in increased expression of SERPINB2 mRNA CTD PMID:30503853 NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888 		JBrowse link
G SIDT2 SID1 transmembrane family member 2 decreases methylation ISO n-hexane results in decreased methylation of SIDT2 promoter CTD PMID:23740543 NCBI chr11:117,178,743...117,197,442
Ensembl chr11:117,178,736...117,197,445 		JBrowse link
G SIPA1L3 signal induced proliferation associated 1 like 3 decreases methylation ISO n-hexane results in decreased methylation of SIPA1L3 promoter CTD PMID:23740543 NCBI chr19:37,907,208...38,208,369
Ensembl chr19:37,907,208...38,208,369 		JBrowse link
G SLC27A3 solute carrier family 27 member 3 decreases methylation ISO n-hexane results in decreased methylation of SLC27A3 promoter CTD PMID:23740543 NCBI chr 1:153,775,407...153,780,157
Ensembl chr 1:153,774,354...153,780,157 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 increases expression ISO n-hexane results in increased expression of SLC39A14 mRNA CTD PMID:23353815 NCBI chr 8:22,367,278...22,434,129
Ensembl chr 8:22,367,278...22,434,129 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 decreases expression ISO n-hexane results in decreased expression of SLC40A1 mRNA CTD PMID:23353815 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758 		JBrowse link
G SLC47A1 solute carrier family 47 member 1 decreases methylation ISO n-hexane results in decreased methylation of SLC47A1 promoter CTD PMID:23740543 NCBI chr17:19,533,854...19,579,034
Ensembl chr17:19,495,385...19,579,034 		JBrowse link
G SLC52A3 solute carrier family 52 member 3 decreases methylation ISO n-hexane results in decreased methylation of SLC52A3 promoter CTD PMID:23740543 NCBI chr20:760,080...780,033
Ensembl chr20:760,080...776,015 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 decreases methylation ISO n-hexane results in decreased methylation of SLC7A5 promoter CTD PMID:23740543 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507 		JBrowse link
G SLCO4C1 solute carrier organic anion transporter family member 4C1 decreases methylation ISO n-hexane results in decreased methylation of SLCO4C1 promoter CTD PMID:23740543 NCBI chr 5:102,233,986...102,296,284
Ensembl chr 5:102,233,986...102,296,284 		JBrowse link
G SRXN1 sulfiredoxin 1 increases expression EXP n-hexane results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200 		JBrowse link
G STAR steroidogenic acute regulatory protein affects expression
affects methylation		 ISO n-hexane affects the expression of STAR mRNA; n-hexane affects the expression of STAR protein
n-hexane affects the methylation of STAR promoter		 CTD PMID:26410608 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G SUGP1 SURP and G-patch domain containing 1 decreases methylation ISO n-hexane results in decreased methylation of SUGP1 promoter CTD PMID:23740543 NCBI chr19:19,276,033...19,320,509
Ensembl chr19:19,276,018...19,320,509 		JBrowse link
G SYNGR1 synaptogyrin 1 decreases methylation ISO n-hexane results in decreased methylation of SYNGR1 promoter CTD PMID:23740543 NCBI chr22:39,349,991...39,385,575
Ensembl chr22:39,349,925...39,385,575 		JBrowse link
G TACSTD2 tumor associated calcium signal transducer 2 increases methylation ISO n-hexane results in increased methylation of TACSTD2 promoter CTD PMID:23740543 NCBI chr 1:58,575,433...58,577,252
Ensembl chr 1:58,575,433...58,577,252 		JBrowse link
G TBCB tubulin folding cofactor B increases methylation ISO n-hexane results in increased methylation of TBCB promoter CTD PMID:23740543 NCBI chr19:36,114,967...36,125,941
Ensembl chr19:36,114,289...36,125,947 		JBrowse link
G TMEM14C transmembrane protein 14C decreases methylation ISO n-hexane results in decreased methylation of TMEM14C promoter CTD PMID:23740543 NCBI chr 6:10,723,070...10,731,127
Ensembl chr 6:10,722,915...10,731,129 		JBrowse link
G TSPYL4 TSPY like 4 decreases methylation ISO n-hexane results in decreased methylation of TSPYL4 promoter CTD PMID:23740543 NCBI chr 6:116,249,964...116,254,075
Ensembl chr 6:116,249,964...116,254,075 		JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP n-hexane results in increased expression of TXNRD1 mRNA CTD PMID:20566472 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
G USP11 ubiquitin specific peptidase 11 increases methylation ISO n-hexane results in increased methylation of USP11 promoter CTD PMID:23740543 NCBI chr  X:47,233,009...47,248,328
Ensembl chr  X:47,232,866...47,248,328 		JBrowse link
G VEGFC vascular endothelial growth factor C decreases methylation ISO n-hexane results in decreased methylation of VEGFC promoter CTD PMID:23740543 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
G VIM vimentin multiple interactions EXP n-hexane metabolite promotes the reaction [VIM protein binds to VIM protein] CTD PMID:6361548 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VSTM4 V-set and transmembrane domain containing 4 decreases methylation ISO n-hexane results in decreased methylation of VSTM4 promoter CTD PMID:23740543 NCBI chr10:49,014,236...49,115,522
Ensembl chr10:49,014,236...49,115,522 		JBrowse link
G WWP1 WW domain containing E3 ubiquitin protein ligase 1 decreases methylation ISO n-hexane results in decreased methylation of WWP1 promoter CTD PMID:23740543 NCBI chr 8:86,342,547...86,468,503
Ensembl chr 8:86,342,547...86,478,420 		JBrowse link
G ZNF593 zinc finger protein 593 increases methylation ISO n-hexane results in increased methylation of ZFP593 promoter CTD PMID:23740543 NCBI chr 1:26,169,908...26,170,873
Ensembl chr 1:26,169,908...26,170,873 		JBrowse link
G ZPR1 ZPR1 zinc finger decreases methylation ISO n-hexane results in decreased methylation of ZPR1 promoter CTD PMID:23740543 NCBI chr11:116,773,799...116,788,023
Ensembl chr11:116,773,799...116,788,039 		JBrowse link
2,5-hexanedione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 increases expression ISO 2,5-hexanedione results in increased expression of ABI2 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 2:203,328,394...203,432,169
Ensembl chr 2:203,328,280...203,447,728 		JBrowse link
G ACO2 aconitase 2 increases expression ISO 2,5-hexanedione results in increased expression of ACO2 protein CTD PMID:19033394 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions
increases expression		 ISO Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of AIF1 protein] CTD PMID:32522579 PMID:32860822 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases expression
decreases phosphorylation		 ISO 2,5-hexanedione results in increased expression of AKT1 mRNA
2,5-hexanedione results in decreased phosphorylation of AKT1 protein		 CTD PMID:33197454 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B decreases expression ISO 2,5-hexanedione results in decreased expression of ALOX15B mRNA CTD PMID:22952946 NCBI chr17:8,039,059...8,049,134
Ensembl chr17:8,039,034...8,049,134 		JBrowse link
G ANGPTL4 angiopoietin like 4 affects expression ISO 2,5-hexanedione affects the expression of ANGPTL4 mRNA CTD PMID:20616210 NCBI chr19:8,364,155...8,374,370
Ensembl chr19:8,363,289...8,374,370 		JBrowse link
G ARG1 arginase 1 decreases expression
multiple interactions		 ISO 2,5-hexanedione results in decreased expression of ARG1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of ARG1 mRNA]		 CTD PMID:32522579 PMID:32860822 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP
ISO		 2,5-hexanedione results in increased expression of BAX mRNA; 2,5-hexanedione results in increased expression of BAX protein CTD PMID:17492505 PMID:21901545 PMID:22337490 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
decreases expression		 ISO
EXP		 2,5-hexanedione results in increased expression of BCL2 protein
2,5-hexanedione results in decreased expression of BCL2 mRNA
2,5-hexanedione results in decreased expression of BCL2 mRNA; 2,5-hexanedione results in decreased expression of BCL2 protein		 CTD PMID:17492505 PMID:21901545 PMID:22337490 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L14 BCL2 like 14 increases expression ISO 2,5-hexanedione results in increased expression of BCL2L14 mRNA CTD PMID:22952946 NCBI chr12:12,049,861...12,099,695
Ensembl chr12:12,049,844...12,211,084 		JBrowse link
G BDNF brain derived neurotrophic factor decreases expression ISO 2,5-hexanedione results in decreased expression of BDNF protein CTD PMID:31760062 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BFAR bifunctional apoptosis regulator increases expression ISO 2,5-hexanedione results in increased expression of BFAR mRNA CTD PMID:22952946 NCBI chr16:14,632,951...14,669,236
Ensembl chr16:14,632,931...14,669,236 		JBrowse link
G CASP1 caspase 1 multiple interactions
increases expression
increases cleavage		 ISO Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of CASP1 protein]
2,5-hexanedione results in increased expression of CASP1 mRNA		 CTD PMID:32522579 PMID:32860822 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 increases expression EXP
ISO		 2,5-hexanedione results in increased expression of CASP3 mRNA; 2,5-hexanedione results in increased expression of CASP3 protein alternative form CTD PMID:17492505 PMID:21901545 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 decreases expression ISO 2,5-hexanedione results in decreased expression of CASP8 protein CTD PMID:33197454 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CCDC171 coiled-coil domain containing 171 increases expression ISO 2,5-hexanedione results in increased expression of CCDC171 mRNA CTD PMID:22952946 NCBI chr 9:15,552,885...16,108,926
Ensembl chr 9:15,553,043...16,061,663 		JBrowse link
G CCDC191 coiled-coil domain containing 191 increases expression ISO 2,5-hexanedione results in increased expression of CCDC191 mRNA CTD PMID:22952946 NCBI chr 3:113,964,137...114,056,613
Ensembl chr 3:113,964,137...114,056,594 		JBrowse link
G CDIN1 CDAN1 interacting nuclease 1 increases expression ISO 2,5-hexanedione results in increased expression of CDIN1 mRNA CTD PMID:22952946 NCBI chr15:36,579,626...36,810,244
Ensembl chr15:36,579,626...36,810,248 		JBrowse link
G CEP112 centrosomal protein 112 increases expression ISO 2,5-hexanedione results in increased expression of CEP112 mRNA CTD PMID:22952946 NCBI chr17:65,635,537...66,192,133
Ensembl chr17:65,635,537...66,192,133 		JBrowse link
G CFAP221 cilia and flagella associated protein 221 increases expression ISO 2,5-hexanedione results in increased expression of CFAP221 mRNA CTD PMID:22952946 NCBI chr 2:119,544,449...119,660,323
Ensembl chr 2:119,544,432...119,662,251 		JBrowse link
G CKMT1B creatine kinase, mitochondrial 1B increases expression ISO 2,5-hexanedione results in increased expression of CKMT1B protein CTD PMID:19033394 NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901
Ensembl chr15:43,593,054...43,604,901 		JBrowse link
G CLCA2 chloride channel accessory 2 multiple interactions ISO [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA CTD PMID:22382377 NCBI chr 1:86,424,171...86,456,553
Ensembl chr 1:86,424,171...86,456,553 		JBrowse link
G CLU clusterin decreases expression
increases expression		 ISO 2,5-hexanedione results in decreased expression of CLU mRNA
2,5-hexanedione results in increased expression of CLU mRNA		 CTD PMID:22952946 PMID:27466211 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CTXN1 cortexin 1 increases expression ISO 2,5-hexanedione results in increased expression of CTXN1 mRNA CTD PMID:22952946 NCBI chr19:7,924,491...7,926,135
Ensembl chr19:7,924,491...7,926,135 		JBrowse link
G DCN decorin increases expression ISO 2,5-hexanedione results in increased expression of DCN mRNA CTD PMID:22952946 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DENND1A DENN domain containing 1A increases expression ISO 2,5-hexanedione results in increased expression of DENND1A mRNA CTD PMID:22952946 NCBI chr 9:123,379,658...123,930,126
Ensembl chr 9:123,379,654...123,930,152 		JBrowse link
G DICER1 dicer 1, ribonuclease III increases expression ISO 2,5-hexanedione results in increased expression of DICER1 mRNA CTD PMID:33197454 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DNAAF11 dynein axonemal assembly factor 11 increases expression ISO 2,5-hexanedione results in increased expression of DNAAF11 mRNA CTD PMID:22952946 NCBI chr 8:132,570,416...132,702,913
Ensembl chr 8:132,570,416...132,675,592 		JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO 2,5-hexanedione results in increased expression of DNAJB4 mRNA CTD PMID:22952946 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964 		JBrowse link
G DPP7 dipeptidyl peptidase 7 multiple interactions ISO [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA CTD PMID:22382377 NCBI chr 9:137,110,546...137,118,306
Ensembl chr 9:137,110,542...137,118,309 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 decreases expression ISO 2,5-hexanedione results in decreased expression of DPYSL2 protein CTD PMID:19033394 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178 		JBrowse link
G EGFR epidermal growth factor receptor increases expression ISO 2,5-hexanedione results in increased expression of EGFR mRNA CTD PMID:16141653 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ERC1 ELKS/RAB6-interacting/CAST family member 1 increases expression ISO 2,5-hexanedione results in increased expression of ERC1 mRNA CTD PMID:22952946 NCBI chr12:989,959...1,495,933
Ensembl chr12:990,509...1,495,933 		JBrowse link
G FASLG Fas ligand increases expression ISO 2,5-hexanedione results in increased expression of FASLG mRNA CTD PMID:22337490 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FASN fatty acid synthase decreases expression ISO 2,5-hexanedione results in decreased expression of FASN protein CTD PMID:19033394 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FCER1G Fc epsilon receptor Ig increases expression ISO 2,5-hexanedione results in increased expression of FCER1G mRNA CTD PMID:22952946 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699 		JBrowse link
G FOXO3 forkhead box O3 increases phosphorylation
decreases expression		 ISO 2,5-hexanedione results in increased phosphorylation of FOXO3 protein
2,5-hexanedione results in decreased expression of FOXO3 mRNA		 CTD PMID:33197454 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression ISO 2,5-hexanedione results in increased expression of GADD45 mRNA CTD PMID:16141653 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GAS2 growth arrest specific 2 increases expression ISO 2,5-hexanedione results in increased expression of GAS2 mRNA CTD PMID:22952946 NCBI chr11:22,626,002...22,813,055
Ensembl chr11:22,625,509...22,813,001 		JBrowse link
G GFAP glial fibrillary acidic protein decreases expression
increases expression		 ISO 2,5-hexanedione results in decreased expression of GFAP protein
2,5-hexanedione results in increased expression of GFAP protein		 CTD PMID:19033394 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GHSR growth hormone secretagogue receptor affects expression ISO 2,5-hexanedione affects the expression of GHSR mRNA CTD PMID:20616210 NCBI chr 3:172,443,291...172,448,456
Ensembl chr 3:172,443,291...172,448,456 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 increases expression ISO 2,5-hexanedione results in increased expression of GLUD1 protein CTD PMID:19033394 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843 		JBrowse link
G GSDMD gasdermin D increases cleavage
multiple interactions		 ISO 2,5-hexanedione results in increased cleavage of GSDMD protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of GSDMD protein]		 CTD PMID:32522579 PMID:32860822 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta decreases expression ISO 2,5-hexanedione results in decreased expression of GSK3B protein CTD PMID:31760062 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSN gelsolin decreases expression ISO 2,5-hexanedione results in decreased expression of GSN protein CTD PMID:19033394 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843 		JBrowse link
G GSTM5 glutathione S-transferase mu 5 decreases expression ISO 2,5-hexanedione results in decreased expression of GSTM5 protein CTD PMID:19033394 NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,780...109,775,428 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases expression ISO 2,5-hexanedione results in decreased expression of GSTP1 mRNA CTD PMID:16141653 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HDGFL1 HDGF like 1 decreases expression ISO 2,5-hexanedione results in decreased expression of HDGFL1 mRNA CTD PMID:22952946 NCBI chr 6:22,569,566...22,571,666
Ensembl chr 6:22,569,566...22,571,666 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression ISO 2,5-hexanedione results in increased expression of HSPA1B mRNA CTD PMID:16141653 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G IER3 immediate early response 3 affects expression ISO 2,5-hexanedione affects the expression of IER3 mRNA CTD PMID:20616210 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G IFT81 intraflagellar transport 81 increases expression ISO 2,5-hexanedione results in increased expression of IFT81 mRNA CTD PMID:22952946 NCBI chr12:110,124,357...110,218,793
Ensembl chr12:110,124,335...110,218,793 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 decreases expression ISO 2,5-hexanedione results in decreased expression of IGFBP3 mRNA CTD PMID:16141653 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions		 ISO 2,5-hexanedione results in increased expression of IL1B mRNA; 2,5-hexanedione results in increased expression of IL1B protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of IL1B protein]		 CTD PMID:16141653 PMID:32522579 PMID:32860822 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G INA internexin neuronal intermediate filament protein alpha decreases expression ISO 2,5-hexanedione results in decreased expression of INA protein CTD PMID:19033394 NCBI chr10:103,277,138...103,290,346
Ensembl chr10:103,277,138...103,290,346 		JBrowse link
G ITGAM integrin subunit alpha M increases expression
multiple interactions		 ISO 2,5-hexanedione results in increased expression of ITGAM protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of ITGAM protein]		 CTD PMID:19464574 PMID:32522579 PMID:32860822 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITGB1 integrin subunit beta 1 decreases expression ISO 2,5-hexanedione results in decreased expression of ITGB1 mRNA CTD PMID:16141653 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G KIAA0930 KIAA0930 increases expression ISO 2,5-hexanedione results in increased expression of KIAA0930 mRNA CTD PMID:22952946 NCBI chr22:45,192,244...45,240,894
Ensembl chr22:45,192,244...45,240,894 		JBrowse link
G KIAA1328 KIAA1328 increases expression ISO 2,5-hexanedione results in increased expression of KIAA1328 mRNA CTD PMID:22952946 NCBI chr18:36,829,127...37,232,172
Ensembl chr18:36,829,106...37,232,172 		JBrowse link
G KIF6 kinesin family member 6 increases expression ISO 2,5-hexanedione results in increased expression of KIF6 mRNA CTD PMID:22952946 NCBI chr 6:39,329,990...39,725,408
Ensembl chr 6:39,329,990...39,725,408 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase decreases expression
multiple interactions		 ISO 2,5-hexanedione results in decreased expression of KIT protein
resveratrol inhibits the reaction [2,5-hexanedione results in decreased expression of KIT protein]		 CTD PMID:17725299 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G LOXL1 lysyl oxidase like 1 increases expression
multiple interactions		 ISO 2,5-hexanedione results in increased expression of LOXL1 protein
2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA		 CTD PMID:22382377 NCBI chr15:73,926,462...73,952,136
Ensembl chr15:73,925,989...73,952,137 		JBrowse link
G LRRC69 leucine rich repeat containing 69 increases expression ISO 2,5-hexanedione results in increased expression of LRRC69 mRNA CTD PMID:22952946 NCBI chr 8:91,102,619...91,219,257
Ensembl chr 8:91,101,832...91,219,257 		JBrowse link
G LYZ lysozyme decreases expression
increases expression		 ISO 2,5-hexanedione results in decreased expression of LYZ2 mRNA
2,5-hexanedione results in increased expression of LYZ2 mRNA		 CTD PMID:22952946 NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234 		JBrowse link
G MACROD1 mono-ADP ribosylhydrolase 1 increases expression
multiple interactions		 ISO 2,5-hexanedione results in increased expression of MACROD1 mRNA
[carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA		 CTD PMID:22382377 NCBI chr11:63,998,558...64,166,113
Ensembl chr11:63,998,558...64,166,113 		JBrowse link
G MAP1A microtubule associated protein 1A decreases expression ISO 2,5-hexanedione results in decreased expression of MAP1A protein CTD PMID:20554699 NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620 		JBrowse link
G MAP1B microtubule associated protein 1B decreases expression ISO 2,5-hexanedione results in decreased expression of MAP1B protein; 2,5-hexanedione results in decreased expression of MAP1B protein modified form CTD PMID:20554699 PMID:31760062 NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565 		JBrowse link
G MAP2 microtubule associated protein 2 decreases expression ISO 2,5-hexanedione results in decreased expression of MAP2 protein modified form CTD PMID:20554699 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO 2,5-hexanedione results in increased expression of MAP3K1 protein CTD PMID:31760062 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152 		JBrowse link
G MAPT microtubule associated protein tau decreases expression ISO 2,5-hexanedione results in decreased expression of MAPT protein modified form CTD PMID:20554699 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MBP myelin basic protein multiple interactions
decreases expression		 ISO Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MBP protein] CTD PMID:32522579 PMID:32860822 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683 		JBrowse link
G MDH1 malate dehydrogenase 1 increases expression ISO 2,5-hexanedione results in increased expression of MDH1 protein CTD PMID:19033394 NCBI chr 2:63,588,963...63,607,197
Ensembl chr 2:63,588,609...63,607,197 		JBrowse link
G MFAP3L microfibril associated protein 3 like increases expression ISO 2,5-hexanedione results in increased expression of MFAP3L mRNA CTD PMID:22952946 NCBI chr 4:169,986,602...170,027,277
Ensembl chr 4:169,986,597...170,033,031 		JBrowse link
G MIR10B microRNA 10b increases expression ISO 2,5-hexanedione results in increased expression of MIR10B mRNA CTD PMID:31760062 NCBI chr 2:176,150,303...176,150,412
Ensembl chr 2:176,150,303...176,150,412 		JBrowse link
G MIR1224 microRNA 1224 increases expression ISO 2,5-hexanedione results in increased expression of MIR1224 mRNA CTD PMID:31760062 NCBI chr 3:184,241,405...184,241,489
Ensembl chr 3:184,241,405...184,241,489 		JBrowse link
G MIR125A microRNA 125a increases expression
decreases expression		 ISO 2,5-hexanedione results in increased expression of MIR125A mRNA
2,5-hexanedione results in decreased expression of MIR125A mRNA		 CTD PMID:31760062 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MIR130B microRNA 130b decreases expression ISO 2,5-hexanedione results in decreased expression of MIR130B mRNA CTD PMID:31760062 NCBI chr22:21,653,304...21,653,385
Ensembl chr22:21,653,304...21,653,385 		JBrowse link
G MIR134 microRNA 134 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR134 mRNA CTD PMID:31760062 NCBI chr14:101,054,687...101,054,759
Ensembl chr14:101,054,687...101,054,759 		JBrowse link
G MIR155 microRNA 155 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR155 mRNA CTD PMID:31760062 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR183 microRNA 183 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR183 mRNA CTD PMID:31760062 NCBI chr 7:129,774,905...129,775,014
Ensembl chr 7:129,774,905...129,775,014 		JBrowse link
G MIR193A microRNA 193a decreases expression ISO 2,5-hexanedione results in decreased expression of MIR193A mRNA CTD PMID:31760062 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR194-2 microRNA 194-2 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR194-2 mRNA CTD PMID:31760062 NCBI chr11:64,891,355...64,891,439
Ensembl chr11:64,891,355...64,891,439 		JBrowse link
G MIR196A1 microRNA 196a-1 increases expression ISO 2,5-hexanedione results in increased expression of MIR196C mRNA CTD PMID:31760062 NCBI chr17:48,632,490...48,632,559
Ensembl chr17:48,632,490...48,632,559 		JBrowse link
G MIR196A2 microRNA 196a-2 increases expression ISO 2,5-hexanedione results in increased expression of MIR196A mRNA CTD PMID:31760062 NCBI chr12:53,991,738...53,991,847
Ensembl chr12:53,991,738...53,991,847 		JBrowse link
G MIR199A2 microRNA 199a-2 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR199A-2 mRNA; 2,5-hexanedione results in decreased expression of MIR199A2 mRNA CTD PMID:31760062 NCBI chr 1:172,144,535...172,144,644
Ensembl chr 1:172,144,535...172,144,644 		JBrowse link
G MIR200C microRNA 200c decreases expression ISO 2,5-hexanedione results in decreased expression of MIR200C mRNA CTD PMID:31760062 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766 		JBrowse link
G MIR202 microRNA 202 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR202 mRNA CTD PMID:31760062 NCBI chr10:133,247,511...133,247,620
Ensembl chr10:133,247,511...133,247,620 		JBrowse link
G MIR206 microRNA 206 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR206 mRNA CTD PMID:31760062 NCBI chr 6:52,144,349...52,144,434
Ensembl chr 6:52,144,349...52,144,434 		JBrowse link
G MIR208A microRNA 208a increases expression ISO 2,5-hexanedione results in increased expression of MIR208A mRNA CTD PMID:31760062 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666 		JBrowse link
G MIR20A microRNA 20a decreases expression ISO 2,5-hexanedione results in decreased expression of MIR20A mRNA CTD PMID:31760062 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR21 microRNA 21 increases expression
decreases expression		 ISO 2,5-hexanedione results in increased expression of MIR21 mRNA
2,5-hexanedione results in decreased expression of MIR21 mRNA		 CTD PMID:31760062 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR212 microRNA 212 increases expression ISO 2,5-hexanedione results in increased expression of MIR212 mRNA CTD PMID:31760062 NCBI chr17:2,050,271...2,050,380
Ensembl chr17:2,050,271...2,050,380 		JBrowse link
G MIR214 microRNA 214 increases expression ISO 2,5-hexanedione results in increased expression of MIR214 mRNA CTD PMID:33197454 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MIR22 microRNA 22 increases expression ISO 2,5-hexanedione results in increased expression of MIR22 mRNA CTD PMID:31760062 NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987 		JBrowse link
G MIR223 microRNA 223 increases expression ISO 2,5-hexanedione results in increased expression of MIR223 mRNA CTD PMID:31760062 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR224 microRNA 224 increases expression ISO 2,5-hexanedione results in increased expression of MIR224 mRNA CTD PMID:31760062 NCBI chr  X:151,958,578...151,958,658
Ensembl chr  X:151,958,578...151,958,658 		JBrowse link
G MIR27A microRNA 27a decreases expression ISO 2,5-hexanedione results in decreased expression of MIR27A mRNA CTD PMID:31760062 NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517 		JBrowse link
G MIR27B microRNA 27b increases expression ISO 2,5-hexanedione results in increased expression of MIR27B mRNA CTD PMID:31760062 NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541 		JBrowse link
G MIR300 microRNA 300 increases expression ISO 2,5-hexanedione results in increased expression of MIR300 mRNA CTD PMID:31760062 NCBI chr14:101,041,363...101,041,445
Ensembl chr14:101,041,363...101,041,445 		JBrowse link
G MIR30A microRNA 30a increases expression ISO 2,5-hexanedione results in increased expression of MIR30A mRNA CTD PMID:31760062 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621 		JBrowse link
G MIR32 microRNA 32 increases expression ISO 2,5-hexanedione results in increased expression of MIR32 mRNA CTD PMID:31760062 NCBI chr 9:109,046,229...109,046,298
Ensembl chr 9:109,046,229...109,046,298 		JBrowse link
G MIR320A microRNA 320a increases expression ISO 2,5-hexanedione results in increased expression of MIR320A mRNA CTD PMID:31760062 NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043 		JBrowse link
G MIR323A microRNA 323a decreases expression ISO 2,5-hexanedione results in decreased expression of MIR323 mRNA CTD PMID:31760062 NCBI chr14:101,025,732...101,025,817
Ensembl chr14:101,025,732...101,025,817 		JBrowse link
G MIR326 microRNA 326 increases expression ISO 2,5-hexanedione results in increased expression of MIR326 mRNA CTD PMID:31760062 NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186 		JBrowse link
G MIR330 microRNA 330 increases expression ISO 2,5-hexanedione results in increased expression of MIR330 mRNA CTD PMID:31760062 NCBI chr19:45,638,994...45,639,087
Ensembl chr19:45,638,994...45,639,087 		JBrowse link
G MIR331 microRNA 331 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR331 mRNA CTD PMID:31760062 NCBI chr12:95,308,420...95,308,513
Ensembl chr12:95,308,420...95,308,513 		JBrowse link
G MIR339 microRNA 339 increases expression ISO 2,5-hexanedione results in increased expression of MIR339 mRNA CTD PMID:31760062 NCBI chr 7:1,022,933...1,023,026
Ensembl chr 7:1,022,933...1,023,026 		JBrowse link
G MIR33A microRNA 33a increases expression ISO 2,5-hexanedione results in increased expression of MIR33 mRNA CTD PMID:31760062 NCBI chr22:41,900,944...41,901,012
Ensembl chr22:41,900,944...41,901,012 		JBrowse link
G MIR345 microRNA 345 increases expression ISO 2,5-hexanedione results in increased expression of MIR345 mRNA CTD PMID:31760062 NCBI chr14:100,307,859...100,307,956
Ensembl chr14:100,307,859...100,307,956 		JBrowse link
G MIR370 microRNA 370 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR370 mRNA CTD PMID:31760062 NCBI chr14:100,911,139...100,911,213
Ensembl chr14:100,911,139...100,911,213 		JBrowse link
G MIR375 microRNA 375 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR375 mRNA CTD PMID:31760062 NCBI chr 2:219,001,645...219,001,708
Ensembl chr 2:219,001,645...219,001,708 		JBrowse link
G MIR412 microRNA 412 increases expression ISO 2,5-hexanedione results in increased expression of MIR412 mRNA CTD PMID:31760062 NCBI chr14:101,065,447...101,065,537
Ensembl chr14:101,065,447...101,065,537 		JBrowse link
G MIR423 microRNA 423 increases expression ISO 2,5-hexanedione results in increased expression of MIR423 mRNA CTD PMID:31760062 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172 		JBrowse link
G MIR433 microRNA 433 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR433 mRNA CTD PMID:31760062 NCBI chr14:100,881,886...100,881,978
Ensembl chr14:100,881,886...100,881,978 		JBrowse link
G MIR450A1 microRNA 450a-1 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR450A1 mRNA CTD PMID:31760062 NCBI chr  X:134,540,341...134,540,431
Ensembl chr  X:134,540,341...134,540,431 		JBrowse link
G MIR487B microRNA 487b increases expression ISO 2,5-hexanedione results in increased expression of MIR487B mRNA CTD PMID:31760062 NCBI chr14:101,046,455...101,046,538
Ensembl chr14:101,046,455...101,046,538 		JBrowse link
G MIR488 microRNA 488 increases expression ISO 2,5-hexanedione results in increased expression of MIR488 mRNA CTD PMID:31760062 NCBI chr 1:177,029,363...177,029,445
Ensembl chr 1:177,029,363...177,029,445 		JBrowse link
G MIR497 microRNA 497 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR497 mRNA CTD PMID:31760062 NCBI chr17:7,017,911...7,018,022
Ensembl chr17:7,017,911...7,018,022 		JBrowse link
G MIR503 microRNA 503 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR503 mRNA CTD PMID:31760062 NCBI chr  X:134,546,328...134,546,398
Ensembl chr  X:134,546,328...134,546,398 		JBrowse link
G MIR541 microRNA 541 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR541 mRNA CTD PMID:31760062 NCBI chr14:101,064,495...101,064,578
Ensembl chr14:101,064,495...101,064,578 		JBrowse link
G MIR542 microRNA 542 increases expression ISO 2,5-hexanedione results in increased expression of MIR542 mRNA CTD PMID:31760062 NCBI chr  X:134,541,341...134,541,437
Ensembl chr  X:134,541,341...134,541,437 		JBrowse link
G MIR551B microRNA 551b decreases expression ISO 2,5-hexanedione results in decreased expression of MIR551B mRNA CTD PMID:31760062 NCBI chr 3:168,551,854...168,551,949
Ensembl chr 3:168,551,854...168,551,949 		JBrowse link
G MIR582 microRNA 582 increases expression ISO 2,5-hexanedione results in increased expression of MIR582 mRNA CTD PMID:31760062 NCBI chr 5:59,703,606...59,703,703
Ensembl chr 5:59,703,606...59,703,703 		JBrowse link
G MIR652 microRNA 652 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR652 mRNA CTD PMID:31760062 NCBI chr  X:110,055,329...110,055,426
Ensembl chr  X:110,055,329...110,055,426 		JBrowse link
G MIR653 microRNA 653 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR653 mRNA CTD PMID:31760062 NCBI chr 7:93,482,760...93,482,855
Ensembl chr 7:93,482,760...93,482,855 		JBrowse link
G MIR665 microRNA 665 increases expression ISO 2,5-hexanedione results in increased expression of MIR665 mRNA CTD PMID:31760062 NCBI chr14:100,875,033...100,875,104
Ensembl chr14:100,875,033...100,875,104 		JBrowse link
G MIR675 microRNA 675 increases expression ISO 2,5-hexanedione results in increased expression of MIR675 mRNA CTD PMID:31760062 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831 		JBrowse link
G MIR7-2 microRNA 7-2 increases expression ISO 2,5-hexanedione results in increased expression of MIR8 mRNA CTD PMID:31760062 NCBI chr15:88,611,825...88,611,934
Ensembl chr15:88,611,825...88,611,934 		JBrowse link
G MIR760 microRNA 760 decreases expression ISO 2,5-hexanedione results in decreased expression of MIR760 mRNA CTD PMID:31760062 NCBI chr 1:93,846,832...93,846,911
Ensembl chr 1:93,846,832...93,846,911 		JBrowse link
G MIR770 microRNA 770 increases expression ISO 2,5-hexanedione results in increased expression of MIR770 mRNA CTD PMID:31760062 NCBI chr14:100,852,390...100,852,487
Ensembl chr14:100,852,390...100,852,487 		JBrowse link
G MIR873 microRNA 873 increases expression ISO 2,5-hexanedione results in increased expression of MIR873 mRNA CTD PMID:31760062 NCBI chr 9:28,888,879...28,888,955
Ensembl chr 9:28,888,879...28,888,955 		JBrowse link
G MIR877 microRNA 877 increases expression ISO 2,5-hexanedione results in increased expression of MIR877 mRNA CTD PMID:31760062 NCBI chr 6:30,584,332...30,584,417
Ensembl chr 6:30,584,332...30,584,417 		JBrowse link
G MIRLET7B microRNA let-7b increases expression ISO 2,5-hexanedione results in increased expression of MIRLET7B mRNA CTD PMID:31760062 NCBI chr22:46,113,686...46,113,768
Ensembl chr22:46,113,686...46,113,768 		JBrowse link
G MIRLET7F1 microRNA let-7f-1 decreases expression ISO 2,5-hexanedione results in decreased expression of MIRLET7F1 mRNA CTD PMID:31760062 NCBI chr 9:94,176,347...94,176,433
Ensembl chr 9:94,176,347...94,176,433 		JBrowse link
G MIRLET7I microRNA let-7i increases expression ISO 2,5-hexanedione results in increased expression of MIRLET7I mRNA CTD PMID:31760062 NCBI chr12:62,603,686...62,603,769
Ensembl chr12:62,603,686...62,603,769 		JBrowse link
G MRC1 mannose receptor C-type 1 decreases expression
multiple interactions		 ISO 2,5-hexanedione results in decreased expression of MRC1 mRNA
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MRC1 mRNA]		 CTD PMID:32522579 PMID:32860822 NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164 		JBrowse link
G MTM1 myotubularin 1 increases expression ISO 2,5-hexanedione results in increased expression of MTM1 mRNA CTD PMID:22952946 NCBI chr  X:150,562,653...150,673,143
Ensembl chr  X:150,568,417...150,673,143 		JBrowse link
G NAPA NSF attachment protein alpha decreases expression ISO 2,5-hexanedione results in decreased expression of NAPA protein CTD PMID:19033394 NCBI chr19:47,484,530...47,515,063
Ensembl chr19:47,487,637...47,515,091 		JBrowse link
G NDUFA10 NADH:ubiquinone oxidoreductase subunit A10 increases expression
decreases expression		 ISO 2,5-hexanedione results in increased expression of NDUFA10 protein
2,5-hexanedione results in decreased expression of NDUFA10 protein		 CTD PMID:19033394 NCBI chr 2:239,892,442...240,025,342
Ensembl chr 2:239,892,450...240,025,743 		JBrowse link
G NEFH neurofilament heavy chain decreases expression ISO 2,5-hexanedione results in decreased expression of NEFH protein CTD PMID:19033394 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NEFL neurofilament light chain decreases expression
multiple interactions		 ISO 2,5-hexanedione results in decreased expression of NEFL protein
Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of NEFL protein]		 CTD PMID:19033394 PMID:32522579 PMID:32860822 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NEFM neurofilament medium chain decreases expression ISO 2,5-hexanedione results in decreased expression of NEFM protein CTD PMID:19033394 NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 increases expression
multiple interactions		 ISO 2,5-hexanedione results in increased expression of NLRP3 mRNA; 2,5-hexanedione results in increased expression of NLRP3 protein
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NLRP3 protein]		 CTD PMID:32522579 PMID:32860822 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NOS2 mRNA] CTD PMID:32522579 PMID:32860822 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO 2,5-hexanedione results in decreased expression of NSF protein CTD PMID:19033394 NCBI chr17:46,590,669...46,757,464
Ensembl chr17:46,590,669...46,757,679 		JBrowse link
G NUPR2 nuclear protein 2, transcriptional regulator increases expression ISO 2,5-hexanedione results in increased expression of NUPR2 mRNA CTD PMID:22952946 NCBI chr 7:56,114,681...56,116,417
Ensembl chr 7:56,114,681...56,116,417 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 decreases expression ISO 2,5-hexanedione results in decreased expression of PDIA3 protein CTD PMID:19033394 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PDLIM3 PDZ and LIM domain 3 decreases expression ISO 2,5-hexanedione results in decreased expression of PDLIM3 protein CTD PMID:19033394 NCBI chr 4:185,500,660...185,535,507
Ensembl chr 4:185,500,660...185,535,507 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 increases expression ISO 2,5-hexanedione results in increased expression of PGAM1 protein CTD PMID:19033394 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 increases expression ISO 2,5-hexanedione results in increased expression of PHOSPHO1 mRNA CTD PMID:22952946 NCBI chr17:49,223,366...49,230,787
Ensembl chr17:49,223,366...49,230,787 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha decreases expression ISO 2,5-hexanedione results in decreased expression of PIK3CA mRNA CTD PMID:33197454 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO 2,5-hexanedione results in decreased expression of PIK3R1 protein CTD PMID:33197454 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO 2,5-hexanedione results in increased expression of PIM1 mRNA CTD PMID:22952946 NCBI chr 6:37,170,152...37,175,428
Ensembl chr 6:37,170,152...37,175,428 		JBrowse link
G PKM pyruvate kinase M1/2 increases expression ISO 2,5-hexanedione results in increased expression of PKM protein CTD PMID:19033394 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G POU2F1 POU class 2 homeobox 1 increases expression ISO 2,5-hexanedione results in increased expression of POU2F1 mRNA CTD PMID:22952946 NCBI chr 1:167,220,885...167,427,345
Ensembl chr 1:167,220,876...167,427,345 		JBrowse link
G PRKCSH PRKCSH beta subunit of glucosidase II decreases expression ISO 2,5-hexanedione results in decreased expression of PRKCSH protein CTD PMID:19033394 NCBI chr19:11,435,635...11,450,968
Ensembl chr19:11,435,284...11,450,968 		JBrowse link
G PTGDS prostaglandin D2 synthase increases expression ISO 2,5-hexanedione results in increased expression of PTGDS mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G PYCARD PYD and CARD domain containing increases expression ISO 2,5-hexanedione results in increased expression of PYCARD mRNA; 2,5-hexanedione results in increased expression of PYCARD protein CTD PMID:32860822 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G PYGB glycogen phosphorylase B decreases expression ISO 2,5-hexanedione results in decreased expression of PYGB protein CTD PMID:19033394 NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012 		JBrowse link
G PYGM glycogen phosphorylase, muscle associated decreases expression ISO 2,5-hexanedione results in decreased expression of PYGM protein CTD PMID:19033394 NCBI chr11:64,746,389...64,760,715
Ensembl chr11:64,746,389...64,759,974 		JBrowse link
G RALGAPA2 Ral GTPase activating protein catalytic subunit alpha 2 increases expression ISO 2,5-hexanedione results in increased expression of RALGAPA2 mRNA CTD PMID:22952946 NCBI chr20:20,389,530...20,712,644
Ensembl chr20:20,389,530...20,712,644 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2,5-hexanedione results in decreased expression of and affects the localization of RELA protein CTD PMID:22337490 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RTKN2 rhotekin 2 increases expression ISO 2,5-hexanedione results in increased expression of RTKN2 mRNA CTD PMID:22952946 NCBI chr10:62,183,900...62,268,844
Ensembl chr10:62,183,035...62,268,844 		JBrowse link
G S100Z S100 calcium binding protein Z increases expression ISO 2,5-hexanedione results in increased expression of S100Z mRNA CTD PMID:22952946 NCBI chr 5:76,850,014...76,952,953
Ensembl chr 5:76,850,001...76,921,650 		JBrowse link
G SCLT1 sodium channel and clathrin linker 1 increases expression ISO 2,5-hexanedione results in increased expression of SCLT1 mRNA CTD PMID:22952946 NCBI chr 4:128,873,241...129,093,539
Ensembl chr 4:128,864,921...129,093,600 		JBrowse link
G SEPTIN8 septin 8 decreases expression ISO 2,5-hexanedione results in decreased expression of SEPTIN8 protein CTD PMID:19033394 NCBI chr 5:132,750,819...132,780,083
Ensembl chr 5:132,750,819...132,807,241 		JBrowse link
G SH2D4A SH2 domain containing 4A decreases expression ISO 2,5-hexanedione results in decreased expression of SH2D4A mRNA CTD PMID:22952946 NCBI chr 8:19,313,693...19,396,218
Ensembl chr 8:19,313,693...19,396,218 		JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 multiple interactions ISO [carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 NCBI chr22:50,672,823...50,733,212
Ensembl chr22:50,674,415...50,733,212 		JBrowse link
G SIL1 SIL1 nucleotide exchange factor increases expression ISO 2,5-hexanedione results in increased expression of SIL1 mRNA CTD PMID:22952946 NCBI chr 5:138,946,724...139,198,368
Ensembl chr 5:138,946,724...139,293,557 		JBrowse link
G SLC10A7 solute carrier family 10 member 7 increases expression ISO 2,5-hexanedione results in increased expression of SLC10A7 mRNA CTD PMID:22952946 NCBI chr 4:146,253,981...146,521,940
Ensembl chr 4:146,253,975...146,522,372 		JBrowse link
G SLTM SAFB like transcription modulator increases expression ISO 2,5-hexanedione results in increased expression of SLTM mRNA CTD PMID:22952946 NCBI chr15:58,879,050...58,933,679
Ensembl chr15:58,879,050...58,933,679 		JBrowse link
G SOD3 superoxide dismutase 3 increases expression ISO 2,5-hexanedione results in increased expression of SOD3 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G SPPL3 signal peptide peptidase like 3 increases expression ISO 2,5-hexanedione results in increased expression of SPPL3 mRNA CTD PMID:22952946 NCBI chr12:120,762,510...120,904,358
Ensembl chr12:120,762,510...120,904,358 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 decreases expression ISO 2,5-hexanedione results in decreased expression of SPTAN1 protein CTD PMID:19033394 NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662 		JBrowse link
G STMN1 stathmin 1 decreases expression ISO 2,5-hexanedione results in decreased expression of STMN1 mRNA CTD PMID:22952946 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991 		JBrowse link
G STRBP spermatid perinuclear RNA binding protein increases expression ISO 2,5-hexanedione results in increased expression of STRBP mRNA CTD PMID:22952946 NCBI chr 9:123,109,494...123,268,586
Ensembl chr 9:123,109,500...123,268,586 		JBrowse link
G STYXL1 serine/threonine/tyrosine interacting like 1 increases expression ISO 2,5-hexanedione results in increased expression of STYXL1 mRNA CTD PMID:22952946 NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 increases expression ISO 2,5-hexanedione results in increased expression of TAX1BP1 mRNA CTD PMID:22952946 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TBC1D5 TBC1 domain family member 5 increases expression ISO 2,5-hexanedione results in increased expression of TBC1D5 mRNA CTD PMID:22952946 NCBI chr 3:17,157,162...17,742,631
Ensembl chr 3:17,157,162...18,444,817 		JBrowse link
G TMEM192 transmembrane protein 192 increases expression ISO 2,5-hexanedione results in increased expression of TMEM192 mRNA CTD PMID:22952946 NCBI chr 4:165,070,608...165,112,860
Ensembl chr 4:165,070,608...165,208,549 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases expression		 ISO Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of TNF mRNA] CTD PMID:32522579 PMID:32860822 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TPI1 triosephosphate isomerase 1 increases expression ISO 2,5-hexanedione results in increased expression of TPI1 mRNA; 2,5-hexanedione results in increased expression of TPI1 protein CTD PMID:19033394 PMID:22952946 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 increases expression ISO 2,5-hexanedione results in increased expression of UBA1 protein CTD PMID:19033394 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128 		JBrowse link
G UBN2 ubinuclein 2 increases expression ISO 2,5-hexanedione results in increased expression of UBN2 mRNA CTD PMID:22952946 NCBI chr 7:139,231,237...139,330,428
Ensembl chr 7:139,230,356...139,308,236 		JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 decreases expression ISO 2,5-hexanedione results in decreased expression of UQCRC2 mRNA CTD PMID:22952946 NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660 		JBrowse link
G VIM vimentin multiple interactions EXP 2,5-hexanedione promotes the reaction [VIM protein binds to VIM protein] CTD PMID:6361548 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G XIAP X-linked inhibitor of apoptosis decreases expression ISO 2,5-hexanedione results in decreased expression of XIAP mRNA CTD PMID:22337490 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
G ZNF169 zinc finger protein 169 decreases expression ISO 2,5-hexanedione results in decreased expression of ZFP169 protein CTD PMID:19033394 NCBI chr 9:94,259,298...94,301,829
Ensembl chr 9:94,259,298...94,301,829 		JBrowse link
G ZNF407 zinc finger protein 407 increases expression ISO 2,5-hexanedione results in increased expression of ZFP407 mRNA CTD PMID:22952946 NCBI chr18:74,597,870...75,065,671
Ensembl chr18:74,597,870...75,065,671 		JBrowse link
hexanal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC018630.2 PRH1-PRR4 readthrough increases methylation EXP n-hexanal results in increased methylation of PRH1-PRR4 gene CTD PMID:30002397 NCBI chr12:10,845,849...11,171,625
Ensembl chr12:10,845,849...11,171,600 		JBrowse link
G ACOT9 acyl-CoA thioesterase 9 increases methylation EXP n-hexanal results in increased methylation of ACOT9 gene CTD PMID:30002397 NCBI chr  X:23,701,055...23,743,276
Ensembl chr  X:23,701,055...23,766,475 		JBrowse link
G ADGRE2 adhesion G protein-coupled receptor E2 increases expression EXP n-hexanal results in increased expression of ADGRE2 mRNA CTD PMID:25014914 NCBI chr19:14,724,171...14,778,560
Ensembl chr19:14,732,392...14,778,560 		JBrowse link
G ADH6 alcohol dehydrogenase 6 (class V) affects expression ISO n-hexanal affects the expression of ADH6 mRNA CTD PMID:26880647 NCBI chr 4:99,202,639...99,219,246
Ensembl chr 4:99,202,638...99,219,537 		JBrowse link
G AIRE autoimmune regulator increases methylation EXP n-hexanal results in increased methylation of AIRE gene CTD PMID:30002397 NCBI chr21:44,285,876...44,298,648
Ensembl chr21:44,285,838...44,298,648 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B affects reduction
increases reduction		 EXP AKR1B1 protein affects the reduction of n-hexanal; AKR1B1 protein affects the reduction of n-hexanal analog
AKR1B1 protein results in increased reduction of n-hexanal		 CTD PMID:9890881 PMID:11306073 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 decreases response to substance ISO AKR7A5 protein results in decreased susceptibility to n-hexanal CTD PMID:24590062 NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,303,965...19,312,144 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 increases oxidation EXP ALDH1A1 protein results in increased oxidation of n-hexanal CTD PMID:23220587 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 increases oxidation ISO ALDH1A2 protein results in increased oxidation of n-hexanal CTD PMID:23220587 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member affects metabolic processing EXP ALDH2 protein polymorphism affects the metabolism of n-hexanal CTD PMID:11744614 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 affects metabolic processing
decreases response to substance		 EXP ALDH3A1 protein affects the metabolism of n-hexanal
ALDH3A1 protein results in decreased susceptibility to n-hexanal		 CTD PMID:11306050 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G ALDH3B1 aldehyde dehydrogenase 3 family member B1 affects binding
decreases response to substance		 EXP n-hexanal binds to ALDH3B1 protein
ALDH3B1 protein results in decreased susceptibility to n-hexanal		 CTD PMID:20699116 NCBI chr11:68,008,547...68,029,276
Ensembl chr11:68,008,578...68,029,282 		JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 decreases response to substance EXP ALDH7A1 protein results in decreased susceptibility to n-hexanal CTD PMID:21338592 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362 		JBrowse link
G B3GALT4 beta-1,3-galactosyltransferase 4 decreases expression EXP n-hexanal results in decreased expression of B3GALT4 mRNA CTD PMID:25014914 NCBI chr 6:33,277,123...33,278,825
Ensembl chr 6:33,277,123...33,284,832 		JBrowse link
G BMP10 bone morphogenetic protein 10 increases methylation EXP n-hexanal results in increased methylation of BMP10 gene CTD PMID:30002397 NCBI chr 2:68,860,909...68,871,397
Ensembl chr 2:68,860,909...68,871,397 		JBrowse link
G C9orf57 chromosome 9 open reading frame 57 decreases methylation EXP n-hexanal results in decreased methylation of C9ORF57 gene CTD PMID:30002397 NCBI chr 9:72,051,376...72,060,613
Ensembl chr 9:72,051,376...72,072,721 		JBrowse link
G CA9 carbonic anhydrase 9 decreases expression EXP n-hexanal results in decreased expression of CA9 mRNA CTD PMID:25014914 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159 		JBrowse link
G CCL13 C-C motif chemokine ligand 13 affects expression ISO n-hexanal affects the expression of CCL12 mRNA CTD PMID:26880647 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610 		JBrowse link
G CCNA1 cyclin A1 increases methylation EXP n-hexanal results in increased methylation of CCNA1 gene CTD PMID:30002397 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCNB1IP1 cyclin B1 interacting protein 1 increases methylation EXP n-hexanal results in increased methylation of CCNB1IP1 gene CTD PMID:30002397 NCBI chr14:20,311,370...20,333,279
Ensembl chr14:20,311,368...20,333,312 		JBrowse link
G CD163L1 CD163 molecule like 1 increases methylation EXP n-hexanal results in increased methylation of CD163L1 gene CTD PMID:30002397 NCBI chr12:7,318,768...7,444,153
Ensembl chr12:7,346,685...7,479,897 		JBrowse link
G CEBPD CCAAT enhancer binding protein delta affects expression ISO n-hexanal affects the expression of CEBPD mRNA CTD PMID:26880647 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164 		JBrowse link
G CEP85 centrosomal protein 85 increases methylation EXP n-hexanal results in increased methylation of CEP85 gene CTD PMID:30002397 NCBI chr 1:26,234,200...26,278,808
Ensembl chr 1:26,234,200...26,278,808 		JBrowse link
G CHD3 chromodomain helicase DNA binding protein 3 increases methylation EXP n-hexanal results in increased methylation of CHD3 gene CTD PMID:30002397 NCBI chr17:7,884,796...7,912,755
Ensembl chr17:7,884,796...7,912,760 		JBrowse link
G CHGA chromogranin A increases expression ISO n-hexanal results in increased expression of CHGA mRNA CTD PMID:26403475 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285 		JBrowse link
G COX17 cytochrome c oxidase copper chaperone COX17 increases methylation EXP n-hexanal results in increased methylation of COX17 gene CTD PMID:30002397 NCBI chr 3:119,663,975...119,677,406
Ensembl chr 3:119,654,513...119,677,454 		JBrowse link
G CSNK1A1P1 casein kinase 1 alpha 1 pseudogene 1 increases methylation EXP n-hexanal results in increased methylation of CSNK1A1P1 gene CTD PMID:30002397 NCBI chr15:36,799,100...36,818,506
Ensembl chr15:36,817,133...36,818,113 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 affects secretion EXP n-hexanal affects the secretion of CXCL8 protein CTD PMID:28947239 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression EXP n-hexanal results in increased expression of CYP1A1 mRNA CTD PMID:25014914 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 affects expression ISO n-hexanal affects the expression of DDIT4 mRNA CTD PMID:26880647 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DHRS9 dehydrogenase/reductase 9 increases expression EXP n-hexanal results in increased expression of DHRS9 mRNA CTD PMID:25014914 NCBI chr 2:169,067,077...169,096,167
Ensembl chr 2:169,064,789...169,096,167 		JBrowse link
G DNAAF2 dynein axonemal assembly factor 2 increases methylation EXP n-hexanal results in increased methylation of DNAAF2 gene CTD PMID:30002397 NCBI chr14:49,625,174...49,635,244
Ensembl chr14:49,625,174...49,635,244 		JBrowse link
G GJA9-MYCBP GJA9-MYCBP readthrough increases methylation EXP n-hexanal results in increased methylation of GJA9-MYCBP gene CTD PMID:30002397 NCBI chr 1:38,862,490...38,881,626 JBrowse link
G H2BC6 H2B clustered histone 6 increases methylation EXP n-hexanal results in increased methylation of H2BC6 gene CTD PMID:30002397 NCBI chr 6:26,183,761...26,184,230
Ensembl chr 6:26,172,059...26,184,655 		JBrowse link
G HMOX1 heme oxygenase 1 decreases expression EXP n-hexanal results in decreased expression of HMOX1 mRNA CTD PMID:28947239 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSD17B11 hydroxysteroid 17-beta dehydrogenase 11 increases methylation EXP n-hexanal results in increased methylation of HSD17B11 gene CTD PMID:30002397 NCBI chr 4:87,336,515...87,391,188
Ensembl chr 4:87,336,515...87,391,188 		JBrowse link
G JCHAIN joining chain of multimeric IgA and IgM increases methylation EXP n-hexanal results in increased methylation of JCHAIN gene CTD PMID:30002397 NCBI chr 4:70,655,541...70,666,508
Ensembl chr 4:70,655,541...70,681,817 		JBrowse link
G KCNF1 potassium voltage-gated channel modifier subfamily F member 1 increases methylation EXP n-hexanal results in increased methylation of KCNF1 gene CTD PMID:30002397 NCBI chr 2:10,911,934...10,914,225
Ensembl chr 2:10,911,934...10,914,225 		JBrowse link
G KIF7 kinesin family member 7 increases methylation EXP n-hexanal results in increased methylation of KIF7 gene CTD PMID:30002397 NCBI chr15:89,617,309...89,663,049
Ensembl chr15:89,608,789...89,663,086 		JBrowse link
G KLF2 KLF transcription factor 2 affects expression ISO n-hexanal affects the expression of KLF2 mRNA CTD PMID:26880647 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685 		JBrowse link
G LHFPL3 LHFPL tetraspan subfamily member 3 increases methylation EXP n-hexanal results in increased methylation of LHFPL3 gene CTD PMID:30002397 NCBI chr 7:104,328,603...104,908,561
Ensembl chr 7:104,328,603...104,908,561 		JBrowse link
G LRRC74A leucine rich repeat containing 74A increases methylation EXP n-hexanal results in increased methylation of LRRC74A gene CTD PMID:30002397 NCBI chr14:76,826,408...76,870,304
Ensembl chr14:76,826,372...76,870,304 		JBrowse link
G MFN1 mitofusin 1 increases methylation EXP n-hexanal results in increased methylation of MFN1 gene CTD PMID:30002397 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MIR101-1 microRNA 101-1 decreases expression ISO n-hexanal results in decreased expression of MIR101A mRNA CTD PMID:26403475 NCBI chr 1:65,058,434...65,058,508
Ensembl chr 1:65,058,434...65,058,508 		JBrowse link
G MIR1224 microRNA 1224 decreases expression ISO n-hexanal results in decreased expression of MIR1224 mRNA CTD PMID:26403475 NCBI chr 3:184,241,405...184,241,489
Ensembl chr 3:184,241,405...184,241,489 		JBrowse link
G MIR1249 microRNA 1249 decreases expression ISO n-hexanal results in decreased expression of MIR1249 mRNA CTD PMID:26403475 NCBI chr22:45,200,954...45,201,019
Ensembl chr22:45,200,954...45,201,019 		JBrowse link
G MIR128-1 microRNA 128-1 increases methylation EXP n-hexanal results in increased methylation of MIR128-1 gene CTD PMID:30002397 NCBI chr 2:135,665,397...135,665,478
Ensembl chr 2:135,665,397...135,665,478 		JBrowse link
G MIR1306 microRNA 1306 decreases expression ISO n-hexanal results in decreased expression of MIR1306 mRNA CTD PMID:26403475 NCBI chr22:20,086,058...20,086,142
Ensembl chr22:20,086,058...20,086,142 		JBrowse link
G MIR132 microRNA 132 increases expression ISO n-hexanal results in increased expression of MIR132 mRNA CTD PMID:26403475 NCBI chr17:2,049,908...2,050,008
Ensembl chr17:2,049,908...2,050,008 		JBrowse link
G MIR133A2 microRNA 133a-2 decreases expression ISO n-hexanal results in decreased expression of MIR3582 mRNA CTD PMID:26403475 NCBI chr20:62,564,912...62,565,013
Ensembl chr20:62,564,912...62,565,013 		JBrowse link
G MIR136 microRNA 136 decreases expression ISO n-hexanal results in decreased expression of MIR136 mRNA CTD PMID:26403475 NCBI chr14:100,884,702...100,884,783
Ensembl chr14:100,884,702...100,884,783 		JBrowse link
G MIR145 microRNA 145 decreases expression ISO n-hexanal results in decreased expression of MIR145 mRNA CTD PMID:26403475 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR153-2 microRNA 153-2 decreases expression ISO n-hexanal results in decreased expression of MIR153 mRNA CTD PMID:26403475 NCBI chr 7:157,574,336...157,574,422
Ensembl chr 7:157,574,336...157,574,422 		JBrowse link
G MIR181B1 microRNA 181b-1 decreases expression ISO n-hexanal results in decreased expression of MIR181B1 mRNA CTD PMID:26403475 NCBI chr 1:198,858,873...198,858,982
Ensembl chr 1:198,858,873...198,858,982 		JBrowse link
G MIR184 microRNA 184 decreases expression ISO n-hexanal results in decreased expression of MIR184 mRNA CTD PMID:26403475 NCBI chr15:79,209,788...79,209,871
Ensembl chr15:79,209,788...79,209,871 		JBrowse link
G MIR188 microRNA 188 decreases expression ISO n-hexanal results in decreased expression of MIR188 mRNA CTD PMID:26403475 NCBI chr  X:50,003,503...50,003,588
Ensembl chr  X:50,003,503...50,003,588 		JBrowse link
G MIR190A microRNA 190a decreases expression ISO n-hexanal results in decreased expression of MIR190 mRNA CTD PMID:26403475 NCBI chr15:62,823,957...62,824,041
Ensembl chr15:62,823,957...62,824,041 		JBrowse link
G MIR193A microRNA 193a decreases expression ISO n-hexanal results in decreased expression of MIR193A mRNA CTD PMID:26403475 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR200A microRNA 200a decreases expression ISO n-hexanal results in decreased expression of MIR200A mRNA CTD PMID:26403475 NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952 		JBrowse link
G MIR217 microRNA 217 decreases expression ISO n-hexanal results in decreased expression of MIR217 mRNA CTD PMID:26403475 NCBI chr 2:55,982,967...55,983,076
Ensembl chr 2:55,982,967...55,983,076 		JBrowse link
G MIR221 microRNA 221 decreases expression ISO n-hexanal results in decreased expression of MIR221 mRNA CTD PMID:26403475 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G MIR224 microRNA 224 decreases expression ISO n-hexanal results in decreased expression of MIR224 mRNA CTD PMID:26403475 NCBI chr  X:151,958,578...151,958,658
Ensembl chr  X:151,958,578...151,958,658 		JBrowse link
G MIR299 microRNA 299 decreases expression ISO n-hexanal results in decreased expression of MIR299 mRNA CTD PMID:26403475 NCBI chr14:101,023,794...101,023,856
Ensembl chr14:101,023,794...101,023,856 		JBrowse link
G MIR29B2 microRNA 29b-2 decreases expression ISO n-hexanal results in decreased expression of MIR29B2 mRNA CTD PMID:26403475 NCBI chr 1:207,802,443...207,802,523
Ensembl chr 1:207,802,443...207,802,523 		JBrowse link
G MIR326 microRNA 326 decreases expression ISO n-hexanal results in decreased expression of MIR326 mRNA CTD PMID:26403475 NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186 		JBrowse link
G MIR337 microRNA 337 decreases expression ISO n-hexanal results in decreased expression of MIR337 mRNA CTD PMID:26403475 NCBI chr14:100,874,493...100,874,585
Ensembl chr14:100,874,493...100,874,585 		JBrowse link
G MIR381 microRNA 381 decreases expression ISO n-hexanal results in decreased expression of MIR381 mRNA CTD PMID:26403475 NCBI chr14:101,045,920...101,045,994
Ensembl chr14:101,045,920...101,045,994 		JBrowse link
G MIR411 microRNA 411 decreases expression ISO n-hexanal results in decreased expression of MIR411 mRNA CTD PMID:26403475 NCBI chr14:101,023,325...101,023,420
Ensembl chr14:101,023,325...101,023,420 		JBrowse link
G MIR425 microRNA 425 decreases expression ISO n-hexanal results in decreased expression of MIR425 mRNA CTD PMID:26403475 NCBI chr 3:49,020,148...49,020,234
Ensembl chr 3:49,020,148...49,020,234 		JBrowse link
G MIR431 microRNA 431 decreases expression ISO n-hexanal results in decreased expression of MIR431 mRNA CTD PMID:26403475 NCBI chr14:100,881,007...100,881,120
Ensembl chr14:100,881,007...100,881,120 		JBrowse link
G MIR433 microRNA 433 decreases expression ISO n-hexanal results in decreased expression of MIR433 mRNA CTD PMID:26403475 NCBI chr14:100,881,886...100,881,978
Ensembl chr14:100,881,886...100,881,978 		JBrowse link
G MIR513C microRNA 513c decreases expression ISO n-hexanal results in decreased expression of MIR3585 mRNA CTD PMID:26403475 NCBI chr  X:147,189,704...147,189,787
Ensembl chr  X:147,189,704...147,189,787 		JBrowse link
G MIR541 microRNA 541 decreases expression ISO n-hexanal results in decreased expression of MIR541 mRNA CTD PMID:26403475 NCBI chr14:101,064,495...101,064,578
Ensembl chr14:101,064,495...101,064,578 		JBrowse link
G MIR583 microRNA 583 increases methylation EXP n-hexanal results in increased methylation of MIR583 gene CTD PMID:30002397 NCBI chr 5:96,079,138...96,079,212
Ensembl chr 5:96,079,138...96,079,212 		JBrowse link
G MIR7-3 microRNA 7-3 decreases expression ISO n-hexanal results in decreased expression of MIR7B mRNA CTD PMID:26403475 NCBI chr19:4,770,670...4,770,779
Ensembl chr19:4,770,670...4,770,779 		JBrowse link
G MIRLET7F1 microRNA let-7f-1 decreases expression ISO n-hexanal results in decreased expression of MIRLET7F-1 mRNA CTD PMID:26403475 NCBI chr 9:94,176,347...94,176,433
Ensembl chr 9:94,176,347...94,176,433 		JBrowse link
G MMP9 matrix metallopeptidase 9 increases secretion EXP n-hexanal results in increased secretion of MMP9 protein CTD PMID:28947239 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MRPS18A mitochondrial ribosomal protein S18A increases methylation EXP n-hexanal results in increased methylation of MRPS18A gene CTD PMID:30002397 NCBI chr 6:43,671,202...43,687,791
Ensembl chr 6:43,671,202...43,687,791 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP n-hexanal results in decreased expression of MYC mRNA CTD PMID:12921975 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYT1 myelin transcription factor 1 increases methylation EXP n-hexanal results in increased methylation of MYT1 gene CTD PMID:30002397 NCBI chr20:64,164,452...64,242,253
Ensembl chr20:64,102,394...64,242,253 		JBrowse link
G NCOR1P1 NCOR1 pseudogene 1 increases methylation EXP n-hexanal results in increased methylation of NCOR1P1 gene CTD PMID:30002397 NCBI chr20:26,103,416...26,114,041
Ensembl chr20:26,103,416...26,114,028
Ensembl chr20:26,103,416...26,114,028 		JBrowse link
G NFXL1 nuclear transcription factor, X-box binding like 1 increases methylation EXP n-hexanal results in increased methylation of NFXL1 gene CTD PMID:30002397 NCBI chr 4:47,847,233...47,914,667
Ensembl chr 4:47,847,233...47,914,667 		JBrowse link
G NMBR neuromedin B receptor increases methylation EXP n-hexanal results in increased methylation of NMBR gene CTD PMID:30002397 NCBI chr 6:142,074,484...142,147,122
Ensembl chr 6:142,058,330...142,147,122 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex increases methylation EXP n-hexanal results in increased methylation of NUF2 gene CTD PMID:30002397 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764 		JBrowse link
G OR10Z1 olfactory receptor family 10 subfamily Z member 1 increases methylation EXP n-hexanal results in increased methylation of OR10Z1 gene CTD PMID:30002397 NCBI chr 1:158,605,268...158,612,514
Ensembl chr 1:158,605,268...158,612,514 		JBrowse link
G PCDHA10 protocadherin alpha 10 increases methylation EXP n-hexanal results in increased methylation of PCDHA10 gene CTD PMID:30002397 NCBI chr 5:140,855,897...141,012,347
Ensembl chr 5:140,855,883...141,012,347 		JBrowse link
G PCDHA9 protocadherin alpha 9 increases methylation EXP n-hexanal results in increased methylation of PCDHA9 gene CTD PMID:30002397 NCBI chr 5:140,847,772...141,012,347
Ensembl chr 5:140,847,772...141,012,347 		JBrowse link
G PDE4A phosphodiesterase 4A increases methylation EXP n-hexanal results in increased methylation of PDE4A gene CTD PMID:30002397 NCBI chr19:10,416,773...10,469,631
Ensembl chr19:10,416,773...10,469,630 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 increases methylation EXP n-hexanal results in increased methylation of PEX2 gene CTD PMID:30002397 NCBI chr 8:76,980,258...77,001,044
Ensembl chr 8:76,980,258...77,001,044 		JBrowse link
G PHACTR1 phosphatase and actin regulator 1 increases methylation EXP n-hexanal results in increased methylation of PHACTR1 gene CTD PMID:30002397 NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446 		JBrowse link
G PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha increases methylation EXP n-hexanal results in increased methylation of PIK3C2A gene CTD PMID:30002397 NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986 		JBrowse link
G PLPPR5 phospholipid phosphatase related 5 increases methylation EXP n-hexanal results in increased methylation of PLPPR5 gene CTD PMID:30002397 NCBI chr 1:98,890,245...99,005,786
Ensembl chr 1:98,890,245...99,227,929 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta increases methylation EXP n-hexanal results in increased methylation of PRKACB gene CTD PMID:30002397 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G REG1A regenerating family member 1 alpha increases methylation EXP n-hexanal results in increased methylation of REG1A gene CTD PMID:30002397 NCBI chr 2:79,120,488...79,123,409
Ensembl chr 2:79,120,362...79,123,409 		JBrowse link
G RPA4 replication protein A4 increases methylation EXP n-hexanal results in increased methylation of RPA4 gene CTD PMID:30002397 NCBI chr  X:96,883,908...96,885,467
Ensembl chr  X:96,883,908...96,885,467 		JBrowse link
G SCARNA3 small Cajal body-specific RNA 3 decreases expression ISO n-hexanal results in decreased expression of SCARNA3 mRNA CTD PMID:26403475 NCBI chr 1:175,968,397...175,968,540
Ensembl chr 1:175,968,398...175,968,540 		JBrowse link
G SLC39A5 solute carrier family 39 member 5 decreases expression EXP n-hexanal results in decreased expression of SLC39A5 mRNA CTD PMID:25014914 NCBI chr12:56,230,051...56,237,846
Ensembl chr12:56,230,049...56,237,846 		JBrowse link
G SLK STE20 like kinase increases methylation EXP n-hexanal results in increased methylation of SLK gene CTD PMID:30002397 NCBI chr10:103,967,140...104,029,233
Ensembl chr10:103,967,140...104,029,233 		JBrowse link
G SNCA synuclein alpha increases methylation EXP n-hexanal results in increased methylation of SNCA gene CTD PMID:30002397 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SNORA58 small nucleolar RNA, H/ACA box 58 decreases expression ISO n-hexanal results in decreased expression of SNORA58 mRNA CTD PMID:26403475 NCBI chr 3:131,478,998...131,479,233
Ensembl chr 3:131,479,097...131,479,233 		JBrowse link
G SPINK4 serine peptidase inhibitor Kazal type 4 increases methylation EXP n-hexanal results in increased methylation of SPINK4 gene CTD PMID:30002397 NCBI chr 9:33,240,167...33,248,567
Ensembl chr 9:33,218,365...33,248,567 		JBrowse link
G STPG4 sperm-tail PG-rich repeat containing 4 increases methylation EXP n-hexanal results in increased methylation of STPG4 gene CTD PMID:30002397 NCBI chr 2:47,086,991...47,155,308
Ensembl chr 2:47,045,538...47,155,308 		JBrowse link
G TDRKH tudor and KH domain containing increases methylation EXP n-hexanal results in increased methylation of TDRKH gene CTD PMID:30002397 NCBI chr 1:151,766,486...151,790,534
Ensembl chr 1:151,770,107...151,791,416 		JBrowse link
G THUMPD3 THUMP domain containing 3 increases methylation EXP n-hexanal results in increased methylation of THUMPD3 gene CTD PMID:30002397 NCBI chr 3:9,363,054...9,386,791
Ensembl chr 3:9,362,971...9,386,791 		JBrowse link
G TNF tumor necrosis factor increases expression EXP n-hexanal results in increased expression of TNF mRNA CTD PMID:28947239 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 decreases expression EXP n-hexanal results in decreased expression of TP53 mRNA CTD PMID:12921975 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TRIM27 tripartite motif containing 27 increases methylation EXP n-hexanal results in increased methylation of TRIM27 gene CTD PMID:30002397 NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988 		JBrowse link
G TTTY5 testis expressed transcript, Y-linked 5 increases methylation EXP n-hexanal results in increased methylation of TTTY5 gene CTD PMID:30002397 NCBI chr  Y:22,296,798...22,298,876
Ensembl chr  Y:22,296,798...22,298,876 		JBrowse link
G UBXN4 UBX domain protein 4 increases methylation EXP n-hexanal results in increased methylation of UBXN4 gene CTD PMID:30002397 NCBI chr 2:135,741,855...135,785,056
Ensembl chr 2:135,741,734...135,785,056 		JBrowse link
G UGT2B10 UDP glucuronosyltransferase family 2 member B10 increases methylation EXP n-hexanal results in increased methylation of UGT2B10 gene CTD PMID:30002397 NCBI chr 4:68,815,994...68,832,023
Ensembl chr 4:68,815,994...68,832,023 		JBrowse link
G WDR75 WD repeat domain 75 increases methylation EXP n-hexanal results in increased methylation of WDR75 gene CTD PMID:30002397 NCBI chr 2:189,441,474...189,475,552
Ensembl chr 2:189,441,446...189,475,552 		JBrowse link
G ZFHX2 zinc finger homeobox 2 increases methylation EXP n-hexanal results in increased methylation of ZFHX2 gene CTD PMID:30002397 NCBI chr14:23,520,857...23,555,952
Ensembl chr14:23,520,857...23,556,192 		JBrowse link
G ZNF525 zinc finger protein 525 increases methylation EXP n-hexanal results in increased methylation of ZNF525 gene CTD PMID:30002397 NCBI chr19:53,365,705...53,386,590
Ensembl chr19:53,365,693...53,392,217 		JBrowse link
hexane-1,6-diamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRL3 adhesion G protein-coupled receptor L3 increases abundance EXP ADGRL3 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr 4:61,200,326...62,078,335
Ensembl chr 4:61,200,326...62,078,335 		JBrowse link
G MPO myeloperoxidase multiple interactions EXP [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]] CTD PMID:34085520 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G SCARA5 scavenger receptor class A member 5 increases abundance EXP SCARA5 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr 8:27,869,883...27,992,673
Ensembl chr 8:27,869,883...27,992,673 		JBrowse link
monohexyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 increases activity EXP mono-n-hexyl phthalate results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha affects binding EXP mono-n-hexyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta affects binding EXP mono-n-hexyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma affects binding EXP mono-n-hexyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      biological role 25929
        aetiopathogenetic role 24592
          neurotoxin 20811
            hexane 429
              1-iminohexane-2,3,4,5-tetrol 0
              1-isothiocyanato-6-(methylsulfanyl)hexane 0
              1-nitrohexane 0
              2,3,5-trimethylhexane 0
              2,4-dimethylhexane 0
              2,5-hexanedione 188
              2-hexanamine 0
              3-hexanone 0
              3-mercaptohexanol + 0
              3-methoxy-3-methylhexane 0
              5-iminohexane-1,2,3,4,6-pentol 0
              7-(methylthio)heptanonitrile oxide 0
              hexanal 113
              hexane-1,6-diamine + 3
              hexane-1,6-diol + 0
              hexane-2,5-diol + 0
              hexanol + 4
              hexyl group 0
              perfluorohexane 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    main group molecular entity 25834
                      s-block molecular entity 25166
                        hydrogen molecular entity 24765
                          hydrides 22965
                            organic hydride 21924
                              organic fundamental parent 21924
                                hydrocarbon 21350
                                  alkane 15196
                                    hexane 429
                                      1-iminohexane-2,3,4,5-tetrol 0
                                      1-isothiocyanato-6-(methylsulfanyl)hexane 0
                                      1-nitrohexane 0
                                      2,3,5-trimethylhexane 0
                                      2,4-dimethylhexane 0
                                      2,5-hexanedione 188
                                      2-hexanamine 0
                                      3-hexanone 0
                                      3-mercaptohexanol + 0
                                      3-methoxy-3-methylhexane 0
                                      5-iminohexane-1,2,3,4,6-pentol 0
                                      7-(methylthio)heptanonitrile oxide 0
                                      hexanal 113
                                      hexane-1,6-diamine + 3
                                      hexane-1,6-diol + 0
                                      hexane-2,5-diol + 0
                                      hexanol + 4
                                      hexyl group 0
                                      perfluorohexane 0
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